{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:35:26Z","timestamp":1787585726649,"version":"build-2736575974"},"reference-count":58,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T00:00:00Z","timestamp":1787356800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>The Myval balloon-expandable transcatheter heart valve was developed for transcatheter aortic valve implantation, but its broad 20\u201332 mm size matrix and controlled deployment have prompted use in non-aortic landing zones. This narrative review critically synthesizes Myval-specific case reports, case series, and observational cohorts, together with relevant platform-level evidence, addressing device design, anatomical selection, imaging, procedural strategy, clinical outcomes, and evidence gaps. Reported applications include mitral valve-in-valve, valve-in-ring, and valve-in-mitral annular calcification; tricuspid valve-in-valve and valve-in-ring; and pulmonary implantation in conduits, surgical bioprostheses, and selected native or patched right ventricular outflow tracts. Outcomes appear most predictable within circular stented surgical bioprostheses, whereas non-circular rings, severe mitral annular calcification, and compliant or aneurysmal outflow tracts present greater risks of inadequate anchoring, paravalvular regurgitation, embolization, frame deformation, left ventricular outflow tract obstruction, and coronary compression. Intermediate and extra-large diameters increase the available nominal sizing options; however, no clinical evidence demonstrates that this reduces embolization, paravalvular regurgitation, residual gradients, or reintervention. The available data document procedural feasibility in anatomically selected patients but are predominantly observational, with limited independent adjudication and follow-up. These procedures are generally off-label and should remain individualized Heart Team decisions; prospective multicenter studies are required to define comparative safety, antithrombotic management, durability, and lifetime reintervention strategies.<\/jats:p>","DOI":"10.3390\/bioengineering13090957","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T14:49:34Z","timestamp":1787582974000},"page":"957","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Myval Beyond the Aortic Valve: Device\u2013Anatomy Interaction, Procedural Strategy, and Clinical Evidence in Mitral, Tricuspid, and Pulmonary Positions"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7155-9907","authenticated-orcid":false,"given":"Georgios E.","family":"Papadopoulos","sequence":"first","affiliation":[{"name":"2nd Cardiology Department, Interbalkan Medical Center, 57001 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4444-3781","authenticated-orcid":false,"given":"Ilias","family":"Ninios","sequence":"additional","affiliation":[{"name":"2nd Cardiology Department, Interbalkan Medical Center, 57001 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3080-5729","authenticated-orcid":false,"given":"Sotirios","family":"Evangelou","sequence":"additional","affiliation":[{"name":"2nd Cardiology Department, Interbalkan Medical Center, 57001 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apostolia","family":"Marvaki","sequence":"additional","affiliation":[{"name":"2nd Cardiology Department, Interbalkan Medical Center, 57001 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5600-7454","authenticated-orcid":false,"given":"Maria","family":"Kalaitzoglou","sequence":"additional","affiliation":[{"name":"2nd Cardiology Department, Interbalkan Medical Center, 57001 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Ioannides","sequence":"additional","affiliation":[{"name":"2nd Cardiology Department, Interbalkan Medical Center, 57001 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7406-5427","authenticated-orcid":false,"given":"Grigorios","family":"Giamouzis","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Thessaly, 41110 Larissa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0390-7172","authenticated-orcid":false,"given":"Vlasis","family":"Ninios","sequence":"additional","affiliation":[{"name":"2nd Cardiology Department, Interbalkan Medical Center, 57001 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/eurheartj\/ehaa554","article-title":"2020 ESC Guidelines for the management of adult congenital heart disease","volume":"42","author":"Baumgartner","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"4635","DOI":"10.1093\/eurheartj\/ehaf194","article-title":"2025 ESC\/EACTS Guidelines for the management of valvular heart disease","volume":"46","author":"Praz","year":"2025","journal-title":"Eur. Heart J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jacc.2023.10.014","article-title":"Cardiac Reoperation or Transcatheter Mitral Valve Replacement for Patients with Failed Mitral Prostheses","volume":"83","author":"Ueyama","year":"2024","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1016\/j.jcin.2023.06.041","article-title":"5-Year Prospective Evaluation of Mitral Valve-in-Valve, Valve-in-Ring, and Valve-in-MAC Outcomes: MITRAL Trial Final Results","volume":"16","author":"Guerrero","year":"2023","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1093\/eurheartj\/ehy590","article-title":"Outcomes of transcatheter mitral valve replacement for degenerated bioprostheses, failed annuloplasty rings, and mitral annular calcification","volume":"40","author":"Yoon","year":"2019","journal-title":"Eur. Heart J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1093\/eurheartj\/ehad663","article-title":"Outcomes of transcatheter pulmonary SAPIEN 3 valve implantation: An international registry","volume":"45","author":"Bentham","year":"2024","journal-title":"Eur. Heart J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1161\/CIRCULATIONAHA.115.019353","article-title":"Transcatheter Tricuspid Valve-in-Valve Implantation for the Treatment of Dysfunctional Surgical Bioprosthetic Valves: An International, Multicenter Registry Study","volume":"133","author":"McElhinney","year":"2016","journal-title":"Circulation"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"96","DOI":"10.21037\/acs-2019-mv-169","article-title":"Mitral valve-in-valve and valve-in-ring: Tips, tricks, and outcomes","volume":"10","author":"Pirelli","year":"2021","journal-title":"Ann. Cardiothorac. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"421","DOI":"10.4244\/EIJ-D-19-00413","article-title":"First-in-human evaluation of a novel balloon-expandable transcatheter heart valve in patients with severe symptomatic native aortic stenosis: The MyVal-1 study","volume":"16","author":"Sharma","year":"2020","journal-title":"EuroIntervention"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1016\/S0140-6736(24)00821-3","article-title":"LANDMARK comparison of early outcomes of newer-generation Myval transcatheter heart valve series with contemporary valves (Sapien and Evolut) in real-world individuals with severe symptomatic native aortic stenosis: A randomised non-inferiority trial","volume":"403","author":"Baumbach","year":"2024","journal-title":"Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/S0140-6736(25)00106-0","article-title":"SAPIEN 3 versus Myval transcatheter heart valves for transcatheter aortic valve implantation (COMPARE-TAVI 1): A multicenter, randomised, non-inferiority trial","volume":"405","author":"Terkelsen","year":"2025","journal-title":"Lancet"},{"key":"ref_12","first-page":"1364","article-title":"Performance of the 32\u2009mm Myval transcatheter heart valve for treatment of aortic stenosis in patients with extremely large aortic annuli in real-world scenario: First global, multicenter experience","volume":"102","author":"Holzamer","year":"2023","journal-title":"Catheter. Cardiovasc. Interv."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Blasco-Turri\u00f3n, S., Serrador-Frutos, A., Jose, J., Sengotuvelu, G., Seth, A., Aldana, V.G., S\u00e1nchez-Luna, J.P., Gonzalez-Guti\u00e9rrez, J.C., Garc\u00eda-G\u00f3mez, M., and G\u00f3mez-Herrero, J. (2022). Transcatheter Mitral Valve-in-Valve Implantation with the Balloon-Expandable Myval Device. J. Clin. Med., 11.","DOI":"10.3390\/jcm11175210"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.carrev.2020.11.018","article-title":"Transcatheter Valve-in-Valve Implantation with a Novel Balloon-Expandable Device in Patients with Bioprosthetic Heart Valve Failure: A Case Series","volume":"28","author":"Ielasi","year":"2021","journal-title":"Cardiovasc. Revasc. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ijcard.2023.01.017","article-title":"Transcatheter valve-in-valve or valve-in-ring implantation with a novel balloon-expandable device in patients with bioprosthetic left side heart valves failure: 1-year follow-up from a multicenter experience","volume":"376","author":"Moscarella","year":"2023","journal-title":"Int. J. Cardiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.hlc.2023.11.011","article-title":"Clinical Outcomes Following Transcatheter Mitral Valve-in-Valve Replacement Using a Meril Myval Transcatheter Heart Valve","volume":"33","author":"Sankardas","year":"2024","journal-title":"Heart Lung Circ."},{"key":"ref_17","first-page":"433","article-title":"Transcatheter Mitral Valve Replacement in Mitral Annular Calcification Using the Novel Myval Valve: Contribution to the Growing Worldwide Experience","volume":"54","author":"Mirzamidinov","year":"2026","journal-title":"Turk. Kardiyol. Dern. Ars."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Nasso, G., Goffredo, G., Pignatelli, A., Marchese, A., Fiore, F., Valenzano, A., Errico, G., Schinco, G., Bonifazi, R., and Loizzo, T. (2026). Case Report: The hybrid cable technique in transcatheter mitral valve implantation with Myval THV-Technical insights from three high-risk cases. Front. Cardiovasc. Med., 13.","DOI":"10.3389\/fcvm.2026.1682730"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"363","DOI":"10.33963\/KP.a2022.0013","article-title":"Transcatheter treatment tricuspid regurgitation by valve-in-ring implantation with a novel balloon-expandable Myval\u00ae THV","volume":"80","author":"Ayhan","year":"2022","journal-title":"Kardiol. Pol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e435","DOI":"10.1016\/j.athoracsur.2021.03.014","article-title":"Transcatheter Tricuspid Valve-in-Valve Implantation with a Novel Balloon Expandable Myval THV","volume":"112","author":"Ayhan","year":"2021","journal-title":"Ann. Thorac. Surg."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Mussayev, A., Alimbayev, S., Tanaliev, N., Kuanyshbek, A., Marat, A., Lesbekov, T., Raissov, Y., Sadykova, A., Kamila, A.K., and Mukarov, M. (2023). Case report: Transcatheter tricuspid valve-in-valve implantation using novel balloon-expandable aortic valve with 1 year follow-up. Front. Cardiovasc. Med., 10.","DOI":"10.3389\/fcvm.2023.1152280"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"ytac131","DOI":"10.1093\/ehjcr\/ytac131","article-title":"Two case reports of transcatheter valve-in-valve implantation of Sapien 3 and MyVal in degenerated biological tricuspid prosthesis valves","volume":"6","author":"Jensen","year":"2022","journal-title":"Eur. Heart J. Case Rep."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1007\/s00246-023-03398-1","article-title":"Multicenter Experience for Early and Mid-Term Outcome of MyVal Transcatheter Pulmonary Valve Implantation","volume":"45","author":"Erdem","year":"2024","journal-title":"Pediatr. Cardiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1017\/S1047951121004650","article-title":"First experiences with Myval Transcatheter Heart Valve System in the treatment of severe pulmonary regurgitation in native right ventricular outflow tract and conduit dysfunction","volume":"32","author":"Odemis","year":"2022","journal-title":"Cardiol. Young"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"293","DOI":"10.4103\/apc.apc_242_20","article-title":"Early multicenter experience of a new balloon expandable MyVal transcatheter heart valve in dysfunctional stenosed right ventricular outflow tract conduits","volume":"14","author":"Sivaprakasam","year":"2021","journal-title":"Ann. Pediatr. Cardiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1017\/S1047951125100590","article-title":"Early outcomes of Myval\u2122 Octacor transcatheter pulmonary valve implantation in dysfunctional right ventricular outflow tract conduits and pulmonary valve bioprostheses: A single-center UK experience","volume":"35","author":"Badawy","year":"2025","journal-title":"Cardiol. Young"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e70598","DOI":"10.1002\/hsr2.70598","article-title":"Percutaneous Pulmonary Valve Implantation In Native Right Ventricular Outflow Tract Using Myval\u2122 Without Pre-Stenting","volume":"8","author":"Manica","year":"2025","journal-title":"Health Sci. Rep."},{"key":"ref_28","first-page":"447","article-title":"The novel balloon-expandable Myval transcatheter heart valve: Systematic review of aortic, mitral, tricuspid and pulmonary indications","volume":"78","author":"Serrador","year":"2025","journal-title":"Rev. Esp. Cardiol. (Engl. Ed.)"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ijcard.2021.06.029","article-title":"Operator preference and determinants of size selection when additional intermediate-size aortic transcatheter heart valves are made available","volume":"338","author":"Kawashima","year":"2021","journal-title":"Int. J. Cardiol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jcin.2023.11.011","article-title":"Technical Aspects for Transcatheter Aortic Valve Replacement with the Novel Balloon-Expandable Myval Octacor","volume":"17","author":"Ielasi","year":"2024","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ijcard.2023.04.003","article-title":"Angiographic quantification of aortic regurgitation following myval octacor implantation; independent core lab adjudication","volume":"382","author":"Elkoumy","year":"2023","journal-title":"Int. J. Cardiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.carrev.2024.01.016","article-title":"Safety and effectiveness of the novel Myval Octacor transcatheter heart valve in severe, symptomatic aortic valve stenosis\u2014A real-world Indian experience (The OCTACOR India Study)","volume":"63","author":"Jose","year":"2024","journal-title":"Cardiovasc. Revasc. Med."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"101924","DOI":"10.1016\/j.ijcha.2026.101924","article-title":"Myval Octacor and Octapro Trans-Catheter Heart Valves in Patients with Severe Pure Non Calcified Native Aortic Regurgitation","volume":"64","author":"Ielasi","year":"2026","journal-title":"IJC Heart Vasc."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s10439-016-1738-8","article-title":"Transcatheter Valve Underexpansion Limits Leaflet Durability: Implications for Valve-in-Valve Procedures","volume":"45","author":"Martin","year":"2017","journal-title":"Ann. Biomed. Eng."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jcin.2013.10.012","article-title":"Effect of valve design on the stent internal diameter of a bioprosthetic valve: A concept of true internal diameter and its implications for the valve-in-valve procedure","volume":"7","author":"Bapat","year":"2014","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1016\/j.jcmg.2020.03.013","article-title":"A Cardiac Computed Tomography-Based Score to Categorize Mitral Annular Calcification Severity and Predict Valve Embolization","volume":"13","author":"Guerrero","year":"2020","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jcct.2023.06.005","article-title":"Technical recommendations for computed tomography guidance of intervention in the right ventricular outflow tract: Native RVOT, conduits and bioprosthetic valves: A white paper of the Society of Cardiovascular Computed Tomography (SCCT), Congenital Heart Surgeons\u2019 Society (CHSS), and Society for Cardiovascular Angiography & Interventions (SCAI)","volume":"18","author":"Han","year":"2024","journal-title":"J. Cardiovasc. Comput. Tomogr."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.jcmg.2016.01.005","article-title":"Predicting LVOT Obstruction in Transcatheter Mitral Valve Implantation: Concept of the Neo-LVOT","volume":"10","author":"Blanke","year":"2017","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jcin.2018.12.001","article-title":"Predictors of Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Replacement","volume":"12","author":"Yoon","year":"2019","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1001\/jamacardio.2020.2974","article-title":"One-Year Outcomes of Mitral Valve-in-Valve Using the SAPIEN 3 Transcatheter Heart Valve","volume":"5","author":"Whisenant","year":"2020","journal-title":"JAMA Cardiol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.jcin.2024.02.012","article-title":"Contemporary 1-Year Outcomes of Mitral Valve-in-Ring with Balloon-Expandable Aortic Transcatheter Valves in the U.S","volume":"17","author":"Guerrero","year":"2024","journal-title":"JACC Cardiovasc Interv."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"363","DOI":"10.5152\/AnatolJCardiol.2021.159","article-title":"Tip-to-base LAMPOON to prevent left ventricular outflow tract obstruction in a valve-in-ring transcatheter mitral valve replacement: First LAMPOON procedure in Turkey and first LAMPOON case for transseptal Myval\u2122 implantation","volume":"25","author":"Isravilov","year":"2021","journal-title":"Anatol. J. Cardiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"e886","DOI":"10.4244\/EIJ-D-24-01083","article-title":"Balloon-assisted translocation of the anterior mitral leaflet to facilitate native mitral replacement","volume":"21","author":"Ninios","year":"2025","journal-title":"EuroIntervention"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1016\/j.jacc.2019.02.076","article-title":"Anterior Leaflet Laceration to Prevent Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Replacement","volume":"73","author":"Khan","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1017\/S1047951125000186","article-title":"Transcatheter tricuspid valve-in-valve implantation in a pediatric patient: A case report","volume":"35","author":"Aykan","year":"2025","journal-title":"Cardiol. Young"},{"key":"ref_46","first-page":"e61059","article-title":"Paravalvular Leak Closure After Transcatheter Tricuspid Valve-in-Ring Implantation: A Case Report","volume":"16","author":"Assaad","year":"2024","journal-title":"Cureus"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.jacc.2018.10.051","article-title":"Mid-Term Valve-Related Outcomes After Transcatheter Tricuspid Valve-in-Valve or Valve-in-Ring Replacement","volume":"73","author":"McElhinney","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"ytaf351","DOI":"10.1093\/ehjcr\/ytaf351","article-title":"Life-threatening pulmonary artery rupture during transcatheter tricuspid valve-in-ring implantation: Case report and management strategies","volume":"9","author":"Sadikoglu","year":"2025","journal-title":"Eur. Heart J. Case Rep."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"105920","DOI":"10.1016\/j.jaccas.2025.105920","article-title":"Transcatheter Valve-In-Valve Implantation in Patients with Fluoroscopically Invisible Tricuspid Valve Prostheses","volume":"30","author":"Farandzha","year":"2025","journal-title":"JACC Case Rep."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"281","DOI":"10.4103\/apc.apc_166_24","article-title":"Transcatheter pulmonary valve implantation with custom-made 35-mm Myval\u2122 transcatheter heart valve","volume":"17","author":"Ramakrishnan","year":"2024","journal-title":"Ann. Pediatr. Cardiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"108879","DOI":"10.1016\/j.jaccas.2026.108879","article-title":"Feasibility of 35-mm Balloon-Expandable Transcatheter Pulmonary Valve Implantation in Extra-Large Native Right Ventricular Outflow Tracts","volume":"31","author":"Maddali","year":"2026","journal-title":"JACC Case Rep."},{"key":"ref_52","first-page":"E38","article-title":"Pulmonary percutaneous valve implantation in large native right ventricular outflow tract with 32\u2009mm Myval transcatheter heart valve","volume":"99","author":"Ballesteros","year":"2022","journal-title":"Catheter. Cardiovasc. Interv."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"ytad322","DOI":"10.1093\/ehjcr\/ytad322","article-title":"Pulmonary valve replacement in a large and tortuous right ventricle outflow tract with a 32 mm Myval valve under local anaesthesia: Challenges and technical considerations: A case report","volume":"7","author":"Houeijeh","year":"2023","journal-title":"Eur. Heart J. Case Rep."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"3948","DOI":"10.1093\/eurheartj\/ehad193","article-title":"2023 ESC Guidelines for the management of endocarditis","volume":"44","author":"Delgado","year":"2023","journal-title":"Eur. Heart J."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"VARC-3 WRITING COMMITTEE, G\u00e9n\u00e9reux, P., Piazza, N., Alu, M.C., Nazif, T., Hahn, R.T., Pibarot, P., Bax, J.J., Leipsic, J.A., and Blanke, P. (2021). Valve Academic Research Consortium 3: Updated endpoint definitions for aortic valve clinical research. Eur. Heart J., 42, 1825\u20131857.","DOI":"10.1093\/eurheartj\/ehaa799"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"e010852","DOI":"10.1161\/CIRCINTERVENTIONS.121.010852","article-title":"Long-Term Outcomes After Melody Transcatheter Pulmonary Valve Replacement in the US Investigational Device Exemption Trial","volume":"15","author":"Jones","year":"2022","journal-title":"Circ. Cardiovasc. Interv."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"4508","DOI":"10.1093\/eurheartj\/ehad653","article-title":"Tricuspid Valve Academic Research Consortium Definitions for Tricuspid Regurgitation and Trial Endpoints","volume":"44","author":"Hahn","year":"2023","journal-title":"Eur. Heart J."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jacc.2015.05.049","article-title":"Clinical Trial Design Principles and Endpoint Definitions for Transcatheter Mitral Valve Repair and Replacement: Part 2: Endpoint Definitions: A Consensus Document From the Mitral Valve Academic Research Consortium","volume":"66","author":"Stone","year":"2015","journal-title":"J. Am. Coll. Cardiol."}],"container-title":["Bioengineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2306-5354\/13\/9\/957\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:13:56Z","timestamp":1787584436000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2306-5354\/13\/9\/957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,22]]},"references-count":58,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["bioengineering13090957"],"URL":"https:\/\/doi.org\/10.3390\/bioengineering13090957","relation":{},"ISSN":["2306-5354"],"issn-type":[{"value":"2306-5354","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,22]]}}}