{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T19:18:15Z","timestamp":1787944695114,"version":"build-2784847793"},"reference-count":100,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National High-Level Hospital Clinical Research Funding","award":["2025-PUMCH-C-002"],"award-info":[{"award-number":["2025-PUMCH-C-002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioengineering"],"abstract":"<jats:p>Wearable technologies are reshaping gait rehabilitation by shifting assessment and therapy from intermittent, clinic-based observation to continuous, data-driven, and adaptive care. This narrative review synthesizes the biomechanical basis of gait instability, the architecture and classification of wearable rehabilitation systems, and the clinical evidence for motion sensors, smart insoles, biofeedback devices, robotic and orthotic wearables, neuromodulatory systems, immersive platforms, and artificial intelligence (AI)-enabled closed-loop interventions. Its main contribution is an integrated framework that links AI, digital biomarkers, device components, adaptive control, and translational implementation, rather than treating wearable rehabilitation as a device-only or disease-specific topic. Current evidence indicates that these technologies can improve gait speed, symmetry, balance, endurance, fall-risk monitoring, and dual-task performance in neurological, musculoskeletal, frailty-related, and aging populations. However, the field is still limited by heterogeneous protocols, small samples, limited longitudinal validation, insufficient device standardization, usability barriers, cybersecurity concerns, uncertain reimbursement, and restricted interoperability with healthcare systems. Future progress will depend on multimodal sensor fusion, explainable and federated AI, digital twins, adaptive wearable robotics, tele-rehabilitation pathways, and large-scale pragmatic trials that validate effectiveness in real-world rehabilitation settings.<\/jats:p>","DOI":"10.3390\/bioengineering13091002","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T18:33:52Z","timestamp":1787942032000},"page":"1002","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Wearable Technologies for Gait Instability Rehabilitation: Mechanisms, Clinical Evidence, and Future Directions"],"prefix":"10.3390","volume":"13","author":[{"given":"Lijin","family":"Liu","sequence":"first","affiliation":[{"name":"Stem Cell Facility, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100007, China"},{"name":"State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100007, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changfa","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Beijing Jishuitan Hospital, Capital Medical University, Beijing 102208, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongyin","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100007, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100007, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihua","family":"Li","sequence":"additional","affiliation":[{"name":"Stem Cell Facility, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100007, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Infrastructures for Translational Medicine (PUMCH), Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100007, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihong","family":"Wu","sequence":"additional","affiliation":[{"name":"Stem Cell Facility, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100007, China"},{"name":"State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100007, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.amjmed.2017.11.051","article-title":"Gait Disorders","volume":"131","author":"Baker","year":"2017","journal-title":"Am. 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