{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:15:07Z","timestamp":1789679707256,"version":"4.0.1"},"reference-count":67,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biology"],"abstract":"<jats:p>The aim of this systematic review and meta-analysis was to analyze and compare the survival rate and prosthetic and sinus complications of zygomatic dental implants for the rehabilitation of the atrophic edentulous maxilla. Materials and methods: We conducted a systematic literature review and meta-analysis, based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, of clinical studies that evaluated the survival rate and prosthetic and sinus complications of zygomatic dental implants for the rehabilitation of the atrophic edentulous maxilla. Four databases were consulted during the literature search: Pubmed\u2013Medline, Scopus, Embase, and Web of Science. After eliminating duplicate articles and applying the inclusion criteria, 46 articles were selected for the qualitative analysis and 32 for the quantitative analysis. Results: Four randomized controlled trials, 19 prospective clinical studies, 20 retrospective studies, and 3 case series were included in the meta-analysis. Conventional dental implants failure (n = 3549) were seen in 2.89% (IC-95% 1.83\u20133.96%), while zygomatic dental implants failure (n = 1895) were seen in 0.69% (IC-95% 0.21\u20131.16%). The measure of the effect size used was the Odds Ratio, which was estimated at 2.05 with a confidence interval of 95% between 1.22 and 3.44 (z test = 2.73; p-value = 0.006). The failure risk of conventional dental implants is 2.1 times higher than that of zygomatic dental implants. Slight heterogeneity was determined in the meta-analysis between 23 combined studies (Q test = 32.4; p-value = 0.070; I2 = 32.1%). Prosthetic complications were recorded in 4.9% (IC-95% 2.7\u20137.3%) and mild heterogeneity was observed in a meta-analysis of 28 combined studies (Q test = 88.2; p-value = 0.001; I2 = 69.4%). Sinus complications were seen in 4.7% (IC-95% 2.8\u20136.5%) and mild heterogeneity was observed in a meta-analysis of 32 combined studies (Q test = 75.3; p-value = 0.001; I2 = 58.8%). Conclusions: The high survival rate and low prosthetic and sinus complications related to zygomatic dental implants suggest the use of zygomatic dental implants for the rehabilitation of the atrophic edentulous maxilla.<\/jats:p>","DOI":"10.3390\/biology10070601","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T10:52:46Z","timestamp":1624963966000},"page":"601","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Survival Rate and Prosthetic and Sinus Complications of Zygomatic Dental Implants for the Rehabilitation of the Atrophic Edentulous Maxilla: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"10","author":[{"given":"David","family":"Guti\u00e9rrez Mu\u00f1oz","sequence":"first","affiliation":[{"name":"Department of Implant Surgery, Faculty of Health Sciences, Alfonso X el Sabio University, 28691 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Obrador Aldover","sequence":"additional","affiliation":[{"name":"Department of Implant Surgery, Faculty of Health Sciences, Alfonso X el Sabio University, 28691 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1lvaro","family":"Zubizarreta-Macho","sequence":"additional","affiliation":[{"name":"Department of Implant Surgery, Faculty of Health Sciences, Alfonso X el Sabio University, 28691 Madrid, Spain"},{"name":"Department of Surgery, Faculty of Medicine and Dentistry, University of Salamanca, 37008 Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9ctor","family":"Gonz\u00e1lez Men\u00e9ndez","sequence":"additional","affiliation":[{"name":"Department of Implant Surgery, Faculty of Health Sciences, Alfonso X el Sabio University, 28691 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Lorrio Castro","sequence":"additional","affiliation":[{"name":"Department of Implant Surgery, Faculty of Health Sciences, Alfonso X el Sabio University, 28691 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Pe\u00f1arrocha-Oltra","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3952-7681","authenticated-orcid":false,"given":"Jos\u00e9 Mar\u00eda","family":"Montiel-Company","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sof\u00eda","family":"Hern\u00e1ndez Montero","sequence":"additional","affiliation":[{"name":"Department of Implant Surgery, Faculty of Health Sciences, Alfonso X el Sabio University, 28691 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/cid.12007","article-title":"The long-term use of zygomatic implants: A 10-year clinical and radiographic report","volume":"16","author":"Aparicio","year":"2014","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1054\/ijom.2001.0197","article-title":"Bone graft remodelling and implant success rate in the treatment of the severely resorbed maxilla: A 5-year longitudinal study","volume":"31","author":"Nystrom","year":"2002","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijom.2008.10.009","article-title":"Reconstruction of the atrophic maxilla with interpositional bone grafting\/Le Fort I osteotomy and endosteal implants: A 11\u201316 year follow-up","volume":"38","author":"Nilson","year":"2009","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/0278-2391(94)90283-6","article-title":"Varying treatment strategies for reconstruction of maxillary atrophy with implants: Results in 98 patients","volume":"52","author":"Jensen","year":"1994","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_5","first-page":"571","article-title":"Le Fort I osteotomy with interpositional bone grafts and implants for rehabilitation of the severely resorbed maxilla: A 2-stage procedure","volume":"14","author":"Kahnberg","year":"1999","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_6","first-page":"303","article-title":"Implant treatment in edentulous maxillae: A 5-year follow-up report on patients with different degrees of jaw resorption","volume":"10","author":"Jemt","year":"1995","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1708-8208.2005.tb00060.x","article-title":"Evaluation of 31 zygomatic implants and 74 regular dental implants used in 16 patients for prosthetic reconstruction of the atrophic maxilla with cross-arch fixed bridges","volume":"7","author":"Becktor","year":"2005","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/jre.12860","article-title":"Analysis of galectin-3 levels as a source of coronary heart disease risk during periodontitis","volume":"56","author":"Isola","year":"2021","journal-title":"J. Periodontal Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/cid.12694","article-title":"Use of IL-1 \u03b2, IL-6, TNF-\u03b1, and MMP-8 biomarkers to distinguish peri-implant diseases: A systematic review and meta-analysis","volume":"21","author":"Ghassib","year":"2019","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_10","first-page":"937","article-title":"Immediate function with the zygomatic implant: A graftless solution for the patient with mild to advanced atrophy of the maxilla","volume":"21","author":"Bedrossian","year":"2006","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_11","first-page":"141","article-title":"Clinical outcome of 42 patients treated with 81 immediately loaded zygomatic implants: A 12-to-42 month retrospective study","volume":"1","author":"Malevez","year":"2008","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1708-8208.2007.00046.x","article-title":"The establishment of a protocol for the total rehabilitation of atrophic maxillae employing four zygomatic fixtures in an immediate loading system: A 30-month clinical and radiographic follow-up","volume":"9","author":"Duarte","year":"2007","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/S0022-3913(08)60237-1","article-title":"A new approach to rehabilitate the severely atrophic maxilla using extramaxillary anchored implants in immediate function: A pilot study","volume":"100","author":"Lopes","year":"2008","journal-title":"J. Prosthet. Dent."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/j.1600-0757.2008.00259.x","article-title":"The use of zygomatic implants for prosthetic rehabilitation of the severely resorbed maxilla","volume":"47","author":"Aparicio","year":"2008","journal-title":"Periodontology 2000"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1046\/j.1600-0501.2003.00985.x","article-title":"Clinical outcome of 103 consecutive zygomatic implants: A 6\u201348 months follow-up study","volume":"15","author":"Malevez","year":"2004","journal-title":"Clin. Oral Implants Res."},{"key":"ref_16","first-page":"323","article-title":"Immediate function of four zygomatic implants: A 1-year report of a prospective study","volume":"3","author":"Davo","year":"2010","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s11739-009-0323-7","article-title":"Measuring the impact of evidence: The Cochrane systematic review of organized stroke care","volume":"4","author":"Liberati","year":"2009","journal-title":"Intern. Emerg. Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: Is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Control. Clin. Trials"},{"key":"ref_19","first-page":"145","article-title":"Immediately loaded zygomatic implants vs conventional dental implants in augmented atrophic maxillae: 1-year post-loading results from a multicentre randomised controlled trial","volume":"11","author":"Felice","year":"2018","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_20","first-page":"147","article-title":"Conventional drills vs. piezoelectric surgery preparation for placement of four immediately loaded zygomatic oncology implants in edentulous maxillae: Results from 1-year split-mouth randomised controlled trial","volume":"10","author":"Esposito","year":"2017","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_21","first-page":"11","article-title":"Immediately loaded zygomatic implants vs conventional dental implants in augmented atrophic maxillae: 4 months post-loading results from a multicentre randomised controlled trial","volume":"11","author":"Esposito","year":"2018","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"862","DOI":"10.11607\/jomi.3706","article-title":"Inferior Meatal Antrostomy as a Prophylactic Maneuver to Prevent Sinusitis After Zygomatic Implant Placement Using the Intrasinusal Technique","volume":"30","year":"2015","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1016\/j.ijom.2017.05.023","article-title":"Immediate full-arch rehabilitation of the severely atrophic maxilla supported by zygomatic implants: A prospective clinical study with minimum follow-up of 6 years","volume":"46","author":"Agliardi","year":"2017","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_24","first-page":"421","article-title":"A study of 25 zygomatic dental implants with 11 to 49 months\u2019 follow-up after loading","volume":"21","author":"Ahlgren","year":"2006","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1708-8208.2008.00130.x","article-title":"Extrasinus zygomatic implants: Three year experience from a new surgical approach for patients with pronounced buccal concavities in the edentulous maxilla","volume":"12","author":"Aparicio","year":"2010","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1708-8208.2006.00009.x","article-title":"A prospective clinical study on titanium implants in the zygomatic arch for prosthetic rehabilitation of the atrophic edentulous maxilla with a follow-up of 6 months to 5 years","volume":"8","author":"Aparicio","year":"2006","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/prd.12038","article-title":"Zygomatic implants: Indications, techniques and outcomes, and the zygomatic success code","volume":"66","author":"Aparicio","year":"2014","journal-title":"Periodontology 2000"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"e77","DOI":"10.1111\/j.1708-8208.2008.00134.x","article-title":"Immediate\/Early loading of zygomatic implants: Clinical experiences after 2 to 5 years of follow-up","volume":"12","author":"Aparicio","year":"2010","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_29","first-page":"1213","article-title":"Rehabilitation of the edentulous maxilla with the zygoma concept: A 7-year prospective study","volume":"25","author":"Bedrossian","year":"2010","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_30","first-page":"861","article-title":"The zygomatic implant: Preliminary data on treatment of severely resorbed maxillae. A clinical report","volume":"17","author":"Bedrossian","year":"2002","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1080\/02844310310023918","article-title":"Zygoma fixture in the management of advanced atrophy of the maxilla: Technique and long-term results","volume":"38","author":"Nilsson","year":"2004","journal-title":"Scand. J. Plast. Reconstr. Surg. Hand Surg."},{"key":"ref_32","first-page":"232","article-title":"Surgical modifications to the Br\u00e5nemark zygomaticus protocol in the treatment of the severely resorbed maxilla: A clinical report","volume":"18","author":"Howes","year":"2003","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.joms.2004.06.030","article-title":"A clinical evaluation of the Zygoma fixture: One year of follow-up at 16 clinics","volume":"62","author":"Hirsch","year":"2004","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_34","first-page":"399","article-title":"Rehabilitation of severely resorbed maxillae with zygomatic implants: An evaluation of implant stability, tissue conditions, and patients\u2019 opinion before and after treatment","volume":"21","author":"Farzad","year":"2006","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1054\/ijom.2002.0337","article-title":"Image-based planning and clinical validation of zygoma and pterygoid implant placement in patients with severe bone atrophy using customized drill guides. Preliminary results from a prospective clinical follow-up study","volume":"32","author":"Vrielinck","year":"2003","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/j.ijom.2012.05.029","article-title":"Immediate occlusal loading of extrasinus zygomatic implants: A prospective cohort study with a follow-up period of 8 years","volume":"41","author":"Senna","year":"2012","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/cid.12047","article-title":"Zygomatic implants placed using the zygomatic anatomy-guided approach versus the classical technique: A proposed system to report rhinosinusitis diagnosis","volume":"16","author":"Aparicio","year":"2014","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1111\/cid.12517","article-title":"Three-year clinical prospective follow-up of extrasinus zygomatic implants for the rehabilitation of the atrophic maxilla","volume":"19","author":"Amorin","year":"2017","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"370","DOI":"10.4103\/1735-3327.218561","article-title":"Zygoma implants in oral rehabilitation: A review of 28 cases","volume":"14","author":"Agbara","year":"2017","journal-title":"Dent. Res. J."},{"key":"ref_40","first-page":"335","article-title":"A retrospective analysis of 110 zygomatic implants in a single-stage immediate loading protocol","volume":"24","author":"Balshi","year":"2009","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Dav\u00f3, R., Bankauskas, S., Laurincikas, R., Ko\u00e7yigit, I.D., and de Val, J.E.M.S. (2020). Clinical Performance of Zygomatic Implants\u2014Retrospective Multicenter Study. J. Clin. Med., 9.","DOI":"10.3390\/jcm9020480"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"S44","DOI":"10.1016\/S0022-3913(07)60007-9","article-title":"Immediate function in the atrophic maxilla using zygoma implants: A preliminary study","volume":"97","author":"Davo","year":"2007","journal-title":"J. Prosthet. Dent."},{"key":"ref_43","first-page":"115","article-title":"Zygomatic implants placed with a two-stage procedure: A 5-year retrospective study","volume":"2","year":"2009","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_44","first-page":"E363","article-title":"Rehabilitation of atrophic maxilla: A review of 101 zygomatic implants","volume":"13","year":"2008","journal-title":"Med. Oral Patol. Oral Cir. Bucal"},{"key":"ref_45","first-page":"267","article-title":"Five-year outcome of a retrospective cohort study on the rehabilitation of completely edentulous atrophic maxillae with immediately loaded zygomatic implants placed extra-maxillary","volume":"7","author":"Lopes","year":"2014","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_46","first-page":"37","article-title":"Three-year outcome of a retrospective cohort study on the rehabilitation of completely edentulous atrophic maxillae with immediately loaded extra-maxillary zygomatic implants","volume":"5","author":"Nobre","year":"2012","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_47","first-page":"426","article-title":"Treatment of atrophic maxilla with zygomatic implants in 29 consecutives patients","volume":"7","author":"Olate","year":"2014","journal-title":"Int. J. Clin. Exp. Med."},{"key":"ref_48","first-page":"665","article-title":"Restoration of the edentulous maxilla using extrasinus zygomatic implants combined with anterior conventional implants: A retrospective study","volume":"26","year":"2011","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.joms.2013.12.029","article-title":"Zygomatic implants for the management of the severely atrophied maxilla: A retrospective analysis of 244 implants","volume":"72","year":"2014","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_50","first-page":"645","article-title":"Rehabilitation of severely atrophic maxillae with fixed implant-supported prostheses using zygomatic implants placed using the sinus slot technique: Clinical report on a series of 21 patients","volume":"22","author":"Boronat","year":"2007","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.ijom.2010.01.009","article-title":"Rehabilitation of totally atrophied maxilla by means of four zygomatic implants and fixed prosthesis: A 6-40-month follow-up","volume":"39","author":"Malevez","year":"2010","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ijom.2013.08.012","article-title":"Treatment of the edentulous atrophic maxilla using zygomatic implants: Evaluation of survival rates over 5\u201310 years","volume":"43","author":"Yates","year":"2014","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Pe\u00f1arrocha-Diago, M., Bernabeu-Mira, J.C., Fern\u00e1ndez-Ru\u00edz, A., Aparicio, C., and Pe\u00f1arrocha-Oltra, D. (2020). Bone Regeneration and Soft Tissue Enhancement Around Zygomatic Implants: Retrospective Case Series. Materials, 13.","DOI":"10.3390\/ma13071577"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"377","DOI":"10.11607\/jomi.5136","article-title":"Retrospective Analysis of 129 Consecutive Zygomatic Implants Used to Rehabilitate Severely Resorbed Maxillae in a Two-Stage Protocol","volume":"32","author":"Sverzut","year":"2017","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.joms.2006.01.021","article-title":"Zygomatic implants\u2014Protocol for immediate occlusal loading: A preliminary report","volume":"64","author":"Chow","year":"2006","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_56","first-page":"308","article-title":"Immediate loading of maxillary fixed prostheses retained by zygomatic and conventional implants: 24-month preliminary data for a series of clinical case reports","volume":"23","author":"Mozzati","year":"2008","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_57","first-page":"788","article-title":"Zygomatic implants using the sinus slot technique: Clinical report of a patient series","volume":"20","author":"Uribe","year":"2005","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/clr.13435","article-title":"The accuracy of static vs. dynamic computer-assited implant surgery in single tooth space: A randomized controlled trial","volume":"30","author":"Kaewsiri","year":"2019","journal-title":"Clin. Oral Implants Res."},{"key":"ref_59","first-page":"9","article-title":"Navigation in implantology","volume":"20","author":"Herklotz","year":"2017","journal-title":"Int. J. Comput. Dent."},{"key":"ref_60","first-page":"305","article-title":"Accuracy in Computer-Aided Implant Surgery\u2014A review","volume":"21","author":"Widmann","year":"2006","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1532-849X.2006.00084.x","article-title":"Use of stereolithographic templates for surgical and prosthodontic implant planning and placement. Part II. A clinical report","volume":"15","author":"Lal","year":"2006","journal-title":"J. Prosthodont."},{"key":"ref_62","first-page":"76","article-title":"Accuracy and the role of experience in dynamic computer guided dental implant surgery: An in-vitro study","volume":"24","author":"Figueiredo","year":"2019","journal-title":"Med. Oral Patol. Oral Cir. Bucal"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1111\/clr.13346","article-title":"The accuracy of static computer-aided implant surgery: A systematic review and meta-analysis","volume":"16","author":"Tahmaseb","year":"2018","journal-title":"Clin. Oral Implants Res."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"205","DOI":"10.11607\/jomi.6966","article-title":"Accuracy of a Dynamic Dental Implant Navigation System in a Private Practice","volume":"34","author":"Stefanelli","year":"2019","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/j.1600-0501.2005.01153.x","article-title":"Accuracy of navigation-guided socket drilling before implant installation compared to the conventional free-hand method in a synthetic edentulous lower jaw model","volume":"16","author":"Hoffmann","year":"2005","journal-title":"Clin. Oral Implants Res."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.11607\/jomi.6585","article-title":"Accuracy of implant placement with a navigation system, a laboratory guide, and freehand drilling","volume":"33","author":"Chen","year":"2018","journal-title":"Int. J. Oral Maxillofac. Implants"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aanat.2019.04.005","article-title":"Advantages and disadvantages of implant navigation surgery. A systematic review","volume":"225","author":"Barootchi","year":"2019","journal-title":"Ann. 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