{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:08:09Z","timestamp":1760234889085,"version":"build-2065373602"},"reference-count":70,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biology"],"abstract":"<jats:p>There are conflicting results existing regarding the association between dental status and metabolic syndrome (MetS). The present research analyzed the associations of the sum of the standard dental unit (SDU) scores of planned (SDU-P) and delivered (SDU-D) dental procedures per patient with MetS components, consequences, and related conditions. The SDU score of each dental procedure represents the time and complexity of the executed procedure. This cross-sectional study analyzed data from the Dental, Oral, Medical Epidemiological (DOME) repository, which includes comprehensive socio-demographic, medical, and dental databases of a nationally representative sample of 132,529 military personnel. Univariate analyses revealed that SDU-P had statistically significant positive associations with all systemic morbidities related to MetS, while the SDU-D exhibited positive associations with some of the systemic morbidities and with lower ORs. SDU-P and SDU-D were associated with worse scores of auxiliary examinations used in the assessment of MetS components. SDU-P retained significant positive associations in the multivariate analysis with impaired glucose tolerance (IGT) (OR = 7.40 (1.91\u201328.57)), deep vein thrombosis (DVT) (OR = 5.61 (1.53\u201320.83)), obstructive sleep apnea (OSA) (OR = 5.05 (2.40\u201310.63)), and fatty liver (OR = 1.82 (1.17\u20132.84)). In contrast, obesity was the only systemic parameter retaining a significant association with SDU-D following multivariate analysis (OR = 1.47 (1.23\u20131.76)). It can be concluded that SDU-P, but not SDU-D, is a better predictor of systemic morbidities related to MetS. In other words, MetS is associated with a higher dental treatment needs burden, rather than with dental treatments performed de facto. Dental and general health authorities should collaborate and share information and focus on reducing common health-related risk factors, such as smoking and sugar consumption, in particular among high-risk populations, such as immigrants and those with lower SES and rural locality.<\/jats:p>","DOI":"10.3390\/biology10070608","type":"journal-article","created":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T02:44:39Z","timestamp":1625107479000},"page":"608","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["\u201cDental Cluster\u201d Versus \u201cMetabolic Cluster\u201d: Analyzing the Associations of Planned and Delivered Dental Procedures with Metabolic Syndrome, Utilizing Data from the Dental, Oral, Medical Epidemiological (DOME) Cross-Sectional Record-Based Nationwide Study"],"prefix":"10.3390","volume":"10","author":[{"given":"Itzhak","family":"Abramovitz","sequence":"first","affiliation":[{"name":"Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel"},{"name":"Hadassah Medical Center, Department of Endodontics, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avraham","family":"Zini","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel"},{"name":"Hadassah Medical Center, Department of Community Dentistry, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Pribluda","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel"},{"name":"Hadassah Medical Center, Department of Endodontics, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4454-5032","authenticated-orcid":false,"given":"Ron","family":"Kedem","sequence":"additional","affiliation":[{"name":"Medical Information Department, General Surgeon Headquarter, Medical Corps, Israel Defense Forces, Tel-Hashomer 02149, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorit","family":"Zur","sequence":"additional","affiliation":[{"name":"Medical Information Department, General Surgeon Headquarter, Medical Corps, Israel Defense Forces, Tel-Hashomer 02149, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noam E.","family":"Protter","sequence":"additional","affiliation":[{"name":"Chief Dental Surgeon & Head of Forensic Unit, Medical Corps, Israel Defense Forces, Tel-Hashomer 02149, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9671-0047","authenticated-orcid":false,"given":"Galit","family":"Almoznino","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel"},{"name":"Hadassah Medical Center, Department of Endodontics, Jerusalem 91120, Israel"},{"name":"Hadassah Medical Center, Department of Oral Medicine, Sedation & Maxillofacial Imaging, Jerusalem 91120, Israel"},{"name":"Big Biomedical Data Research Laboratory, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","article-title":"Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity","volume":"120","author":"Alberti","year":"2009","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.2337\/diacare.28.11.2745","article-title":"Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S","volume":"28","author":"Ford","year":"2005","journal-title":"Diabetes Care"},{"key":"ref_3","unstructured":"(2021, February 15). 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