{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T05:59:40Z","timestamp":1782280780258,"version":"3.54.5"},"reference-count":394,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T00:00:00Z","timestamp":1643932800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biology"],"abstract":"<jats:p>This review outlines the health benefits associated with the regular consumption of tomatoes and tomato products. The first section provides a detailed account of the horticultural techniques that can impact the quality of the fruit and its nutritional properties, including water availability, light intensity, temperature, and growing media. The next section provides information on the components of tomato that are likely to contribute to its health effects. The review then details some of the health benefits associated with tomato consumption, including anticancer properties, cardiovascular and neurodegenerative diseases and skin health. This review also discusses the impact tomatoes can have on the gut microbiome and associated health benefits, including reducing the risk of inflammatory bowel diseases. Other health benefits of eating tomatoes are also discussed in relation to effects on diabetes, the immune response, exercise recovery, and fertility. Finally, this review also addresses the negative effects that can occur as a result of overconsumption of tomato products and lycopene supplements.<\/jats:p>","DOI":"10.3390\/biology11020239","type":"journal-article","created":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T11:35:17Z","timestamp":1643974517000},"page":"239","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":240,"title":["Tomatoes: An Extensive Review of the Associated Health Impacts of Tomatoes and Factors That Can Affect Their Cultivation"],"prefix":"10.3390","volume":"11","author":[{"given":"Edward J.","family":"Collins","sequence":"first","affiliation":[{"name":"IBBS, School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2DT, UK"},{"name":"Faculty of Creative and Cultural Industries, School of Art, Design and Performance, University of Portsmouth, Portsmouth PO1 2UP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cressida","family":"Bowyer","sequence":"additional","affiliation":[{"name":"Faculty of Creative and Cultural Industries, School of Art, Design and Performance, University of Portsmouth, Portsmouth PO1 2UP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Tsouza","sequence":"additional","affiliation":[{"name":"IBBS, School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2DT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mridula","family":"Chopra","sequence":"additional","affiliation":[{"name":"IBBS, School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2DT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,4]]},"reference":[{"key":"ref_1","first-page":"33","article-title":"Tomato-A Natural Medicine and Its Health Benefits","volume":"1","author":"Bhowmik","year":"2012","journal-title":"J. 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