{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T09:55:21Z","timestamp":1771667721999,"version":"3.50.1"},"reference-count":36,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T00:00:00Z","timestamp":1698364800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"research Grant from statutory funding for young researchers\u2014doctoral students","award":["SDUM-GB19\/03\/21"],"award-info":[{"award-number":["SDUM-GB19\/03\/21"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biology"],"abstract":"<jats:p>The existing literature does not address the question of the seasonal impact on pregnancy in Central-Eastern Europe; therefore, this study was designed to investigate the seasonal variation in gestational diabetes mellitus (GDM) based on a recent Polish sample. The data of 30,205 newborns from singleton pregnancies and their mothers, including the date and gestational age of birth, neonatal sex and weight, maternal age and parity, mode of delivery, ethnicity, and a detailed list of comorbidities (including GDM), were retrospectively analysed. The prevalence of GDM was significantly (p &lt; 0.0001) lower in spring (14.71%) than in the other seasons (16.78%). A higher incidence of GDM was observed for mothers who underwent an oral glucose tolerance test from June to August compared to those who were tested from December to February (17.34% vs. 14.75%, p &lt; 0.0001). Similarly, there were significant differences between seasons with higher and lower insolation. The regression analysis revealed that seasonal patterns were significantly associated with the prevalence of GDM. In conclusion, this large retrospective cohort study demonstrated seasonal changes in GDM risk. The observed seasonal patterns may equally refer to mothers of babies born at term and prematurely. Further research concerning GDM risk and other seasonal and gender associations is warranted.<\/jats:p>","DOI":"10.3390\/biology12111376","type":"journal-article","created":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T09:42:52Z","timestamp":1698399772000},"page":"1376","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Seasonal Pattern in Gestational Diabetes Mellitus in Poland: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6554-8761","authenticated-orcid":false,"given":"Marek J.","family":"Walkowiak","sequence":"first","affiliation":[{"name":"Department of Reproduction, Poznan University of Medical Sciences, Polna Str. 33, 60-535 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0257-6180","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"Jamka","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Str. 27\/33, 60-572 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2862-7687","authenticated-orcid":false,"given":"Marcin Piotr","family":"Walkowiak","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Poznan University of Medical Sciences, \u015awi\u0119cickiego Str. 6, 60-781 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2885-9792","authenticated-orcid":false,"given":"Pawe\u0142","family":"Gutaj","sequence":"additional","affiliation":[{"name":"Department of Reproduction, Poznan University of Medical Sciences, Polna Str. 33, 60-535 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5492-8651","authenticated-orcid":false,"given":"Ewa","family":"Wender-O\u017cegowska","sequence":"additional","affiliation":[{"name":"Department of Reproduction, Poznan University of Medical Sciences, Polna Str. 33, 60-535 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1007\/s11136-019-02348-w","article-title":"Birth Weight and Quality of Life in Midlife: A 50-Year Follow-up Study of 2079 Individuals in Denmark","volume":"29","author":"Hegelund","year":"2020","journal-title":"Qual. Life Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/obr.12239","article-title":"Obesity and Vitamin D Deficiency: A Systematic Review and Meta-Analysis","volume":"16","author":"Costa","year":"2015","journal-title":"Obes. Rev."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.numecd.2011.11.001","article-title":"Can Vitamin D Deficiency Cause Diabetes and Cardiovascular Diseases? Present Evidence and Future Perspectives","volume":"22","author":"Muscogiuri","year":"2012","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s00592-014-0564-4","article-title":"Lower Vitamin D Levels at First Trimester Are Associated with Higher Risk of Developing Gestational Diabetes Mellitus","volume":"51","author":"Lacroix","year":"2014","journal-title":"Acta Diabetol."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Al-Ajlan, A., Al-Musharaf, S., Fouda, M.A., Krishnaswamy, S., Wani, K., Aljohani, N.J., Al-Serehi, A., Sheshah, E., Alshingetti, N.M., and Turkistani, I.Z. (2018). Lower Vitamin D Levels in Saudi Pregnant Women Are Associated with Higher Risk of Developing GDM. BMC Pregnancy Childbirth, 18.","DOI":"10.1186\/s12884-018-1723-3"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"182.e1","DOI":"10.1016\/j.ajog.2012.05.022","article-title":"Vitamin D Deficiency in Pregnancy and Gestational Diabetes Mellitus","volume":"207","author":"Burris","year":"2012","journal-title":"Am. J. Obs. Gynecol."},{"key":"ref_7","first-page":"128","article-title":"Gestational Diabetes Mellitus in Plymouth, U.K.: Prevalence, Seasonal Variation and Associated Factors","volume":"51","author":"Janghorbani","year":"2006","journal-title":"J. Reprod. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/j.1464-5491.1995.tb00543.x","article-title":"Is There a Seasonal Variation in the Incidence of Gestational Diabetes?","volume":"12","author":"Moses","year":"1995","journal-title":"Diabet. Med."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Shen, E.X., Moses, R.G., Oats, J.J.N., Lowe, J., and McIntyre, H.D. (2019). Seasonality, Temperature and Pregnancy Oral Glucose Tolerance Test Results in Australia. BMC Pregnancy Childbirth, 19.","DOI":"10.1186\/s12884-019-2413-5"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"180214","DOI":"10.1038\/sdata.2018.214","article-title":"Present and Future K\u00f6ppen-Geiger Climate Classification Maps at 1-Km Resolution","volume":"5","author":"Beck","year":"2018","journal-title":"Sci. Data"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"International Association of Diabetes and Pregnancy Study Groups Consensus Panel, Metzger, B.E., Gabbe, S.G., Persson, B., Buchanan, T.A., Catalano, P.A., Damm, P., Dyer, A.R., de Leiva, A., and Hod, M. (2010). International Association of Diabetes and Pregnancy Study Groups Recommendations on the Diagnosis and Classification of Hyperglycemia in Pregnancy. Diabetes Care, 33, 676\u2013682.","DOI":"10.2337\/dc09-1848"},{"key":"ref_12","first-page":"215","article-title":"Standardy Polskiego Towarzystwa Ginekolog\u00f3w i Polo\u017cnik\u00f3w Post\u0119powania u Kobiet z Cukrzyc\u0105","volume":"2","author":"Celewicz","year":"2017","journal-title":"Ginekol. I Perinatol. Prakt."},{"key":"ref_13","unstructured":"(2023, September 01). Ordinance of Minister of Health of 16 August 2018. On the Organizational Standard of Perinatal Care, (In Polish)."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e700","DOI":"10.20883\/medical.e700","article-title":"Publication Ethics of Human Studies in the Light of the Declaration of Helsinki\u2014A Mini-Review","volume":"91","author":"Guzik","year":"2022","journal-title":"J. Med. Sci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/BF00292547","article-title":"Oral Glucose Tolerance and Ambient Temperature in Non-Diabetic Subjects","volume":"30","author":"Akanji","year":"1987","journal-title":"Diabetologia"},{"key":"ref_16","first-page":"283","article-title":"The Effect of Ambient Temperature on Glucose Tolerance and Its Implications for the Tropics","volume":"43","author":"Akanji","year":"1991","journal-title":"Trop. Geogr. Med."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(94)91711-6","article-title":"Variation in Glucose Tolerance with Ambient Temperature","volume":"344","author":"Schmidt","year":"1994","journal-title":"Lancet"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12940-020-00668-w","article-title":"Climate Factors and Gestational Diabetes Mellitus Risk\u2014A Systematic Review","volume":"19","author":"Preston","year":"2020","journal-title":"Environ. Health"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"55915","DOI":"10.1007\/s11356-021-16230-1","article-title":"Systematic Review and Meta-Analysis on the Association between Seasonal Variation and Gestational Diabetes Mellitus","volume":"28","author":"Khoshhali","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/dme.14236","article-title":"Seasonal Variations in Incidence and Maternal-Fetal Outcomes of Gestational Diabetes","volume":"37","author":"Meek","year":"2020","journal-title":"Diabet. Med."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"140994","DOI":"10.1016\/j.scitotenv.2020.140994","article-title":"Relationship between Environmental Temperature and the Diagnosis and Treatment of Gestational Diabetes Mellitus: An Observational Retrospective Study","volume":"744","author":"Morcillo","year":"2020","journal-title":"Sci. Total Environ."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"136747","DOI":"10.1016\/j.scitotenv.2020.136747","article-title":"A Population-Based Study on the Prevalence of Gestational Diabetes Mellitus in Association with Temperature in Taiwan","volume":"714","author":"Su","year":"2020","journal-title":"Sci. Total Environ."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1007\/s00592-019-01354-1","article-title":"Temporal Trends without Seasonal Effects on Gestational Diabetes Incidence Relate to Reductions in Indices of Insulin Secretion: The Cambridge Baby Growth Study","volume":"56","author":"Petry","year":"2019","journal-title":"Acta Diabetol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1007\/s00125-018-4710-3","article-title":"Impact of Daily Incremental Change in Environmental Temperature on Beta Cell Function and the Risk of Gestational Diabetes in Pregnant Women","volume":"61","author":"Retnakaran","year":"2018","journal-title":"Diabetologia"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1530\/EJE-17-0730","article-title":"The Impact of Environmental Temperature on the Diagnosis of Gestational Diabetes Mellitus","volume":"178","author":"Vasileiou","year":"2018","journal-title":"Eur. J. Endocrinol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"246","DOI":"10.2174\/1871530317666170808155526","article-title":"Impact of Seasonality on Gestational Diabetes Mellitus","volume":"17","author":"Chiefari","year":"2017","journal-title":"Endocr. Metab. Immune Disord. Drug Targets"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"E682","DOI":"10.1503\/cmaj.160839","article-title":"Influence of Environmental Temperature on Risk of Gestational Diabetes","volume":"189","author":"Booth","year":"2017","journal-title":"CMAJ"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"8905474","DOI":"10.1155\/2016\/8905474","article-title":"Seasonal Pattern in the Diagnosis of Gestational Diabetes Mellitus in Southern Sweden","volume":"2016","author":"Katsarou","year":"2016","journal-title":"J. Diabetes Res."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.diabres.2018.11.020","article-title":"Pregnant Women May Be Sweeter in the Summer: Seasonal Changes in Glucose Challenge Tests Results. A Popular Based Study","volume":"147","author":"Wainstock","year":"2019","journal-title":"Diabetes Res. Clin. Pr."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.2337\/dc16-0451","article-title":"Seasonal Changes in the Prevalence of Gestational Diabetes Mellitus","volume":"39","author":"Moses","year":"2016","journal-title":"Diabetes Care"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"e000286","DOI":"10.1136\/bmjdrc-2016-000286","article-title":"Seasonality of Gestational Diabetes Mellitus: A South Australian Population Study","volume":"4","author":"Verburg","year":"2016","journal-title":"BMJ Open Diabetes Res. Care"},{"key":"ref_32","unstructured":"World Health Organization, and Federation, I.D. (2006). Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycaemia: Report of a WHO\/IDF Consultation, World Health Organization."},{"key":"ref_33","unstructured":"World Health Organization (1999). Definition, Diagnosis and Classification of Diabetes Mellitus and Its Complications: Report of a WHO Consultation. Part 1, Diagnosis and Classification of Diabetes Mellitus, World Health Organization."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"112","DOI":"10.5694\/j.1326-5377.1991.tb142140.x","article-title":"The Diagnosis of Gestational Diabetes. Ad Hoc Working Party","volume":"155","author":"Martin","year":"1991","journal-title":"Med. J. Aust."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/0002-9378(82)90349-0","article-title":"Criteria for Screening Tests for Gestational Diabetes","volume":"144","author":"Carpenter","year":"1982","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"e063725","DOI":"10.1136\/bmjopen-2022-063725","article-title":"Seasonal Variation in Gestational Diabetes Mellitus among Women in Norway: A National Population-Based Study","volume":"13","author":"Stalheim","year":"2023","journal-title":"BMJ Open"}],"container-title":["Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-7737\/12\/11\/1376\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:12:48Z","timestamp":1760130768000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-7737\/12\/11\/1376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,27]]},"references-count":36,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2023,11]]}},"alternative-id":["biology12111376"],"URL":"https:\/\/doi.org\/10.3390\/biology12111376","relation":{},"ISSN":["2079-7737"],"issn-type":[{"value":"2079-7737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,27]]}}}