{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T08:37:56Z","timestamp":1762331876972,"version":"build-2065373602"},"reference-count":32,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biology"],"abstract":"<jats:p>Infertility is a major health problem affecting about 15% of couples worldwide. Male etiology is found in almost one-third of cases. This study identified the nature of the relationship between sperm DNA fragmentation (SDF), sperm chromatin condensation (SCC) and sperm parameters. In this study, 80 samples were analyzed using two methods: the TUNEL technique to assess sperm DNA quality and aniline blue coloration to determine the level of chromatic condensation of spermatozoa. In addition, to specify the standard sperm parameters, the spermogram and the spermocytogram were analyzed. The main results revealed a significant difference between SDF and motility and, similarly, between SCC, motility, and teratozoospermia macrocephaly types (p &lt; 0.0001, p &lt; 0.0001, respectively), but no differences between SCC, SDF, and the other sperm parameters (p &gt; 0.99).<\/jats:p>","DOI":"10.3390\/biology14111550","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T07:58:05Z","timestamp":1762329485000},"page":"1550","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Relationship Between Sperm Parameters and Indices of Chromatin Condensation and DNA Fragmentation in Semen"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3060-3507","authenticated-orcid":false,"given":"Othmane","family":"Adli","sequence":"first","affiliation":[{"name":"Laboratory of Sexual and Reproductive Health, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca 20250, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noureddine","family":"Louanjli","sequence":"additional","affiliation":[{"name":"Labomac IVF Centers and Clinical Laboratory Medicine, Casablanca 20100, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9287-0331","authenticated-orcid":false,"given":"Rachid","family":"Aboutaieb","sequence":"additional","affiliation":[{"name":"Laboratory of Sexual and Reproductive Health, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca 20250, Morocco"},{"name":"Department of Urology, Ibn Rochd University Hospital Center, Casablanca 20503, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"01057","DOI":"10.1051\/e3sconf\/202341201057","article-title":"Medically Assisted Procreation: A New Legal Framework to Overcome Infertility in Morocco in the Context of Energy Optimization","volume":"412","author":"Ghallam","year":"2023","journal-title":"E3S Web Conf."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3390\/reprodmed4030020","article-title":"Recent Developments in In Vitro Spermatogenesis and Future Directions","volume":"4","author":"Cho","year":"2023","journal-title":"Reprod. 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