{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:00:07Z","timestamp":1789988407803,"version":"4.0.1"},"reference-count":151,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biology"],"abstract":"<jats:p>Cochliomyia hominivorax, the main etiological agent of traumatic myiasis in the New World, continues to have significant health and economic impacts due to its effects on animal health, livestock production and public health in affected regions. Although conventional control strategies, including the Sterile Insect Technique and chemical insecticides, have substantially reduced its distribution, concerns regarding insecticide resistance, environmental impacts, and recent re-emergence events underscore the need for sustainable alternative control approaches. This review summarizes current advances in the use of EOs and plant-derived bioactive compounds for the management of myiasis-causing flies, with particular emphasis on C. hominivorax, and discusses the emerging role of nanocarrier-based delivery systems in enhancing their biological performance. EOs and their major constituents exhibit larvicidal, ovicidal, adulticidal, repellent, and oviposition-deterrent effects through multiple mechanisms that disrupt essential physiological and developmental processes in insects. Several EOs have shown promising activity against C. hominivorax larvae; however, their practical application is often limited by their high volatility, low aqueous solubility, and physicochemical instability. Nanodelivery systems, including nanoemulsions, polymeric nanoparticles, and solid lipid nanoparticles, offer effective strategies to improve the stability, bioavailability, controlled release, and overall efficacy of plant-derived bioactive compounds. Current evidence indicates that nanodelivery systems enhance the stability and insecticidal efficacy of EOs while reducing the concentrations required to achieve biological activity, supporting their potential for the prevention and treatment of C. hominivorax myiasis. Nevertheless, further in vivo and field studies are required to validate their practical application.<\/jats:p>","DOI":"10.3390\/biology15181654","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T09:01:38Z","timestamp":1789981298000},"page":"1654","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Green Management Strategies for Cochliomyia hominivorax Myiasis: Potential of Essential Oils and Nanodelivery Systems"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0797-9605","authenticated-orcid":false,"given":"Romario","family":"Garc\u00eda-Ponce","sequence":"first","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Gral. Escobedo 66054, NL, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 P.","family":"Villarreal-Villarreal","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Gral. Escobedo 66054, NL, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas J.","family":"Hern\u00e1ndez Escare\u00f1o","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Gral. Escobedo 66054, NL, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0256-536X","authenticated-orcid":false,"given":"Nancy N.","family":"Espinosa-Carranza","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Biol\u00f3gicas, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, San Nicol\u00e1s de los Garza 66455, NL, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6886-4724","authenticated-orcid":false,"given":"Michel St\u00e9phane","family":"Heya","sequence":"additional","affiliation":[{"name":"Facultad de Salud Publica y Nutrici\u00f3n, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Monterrey 64460, NL, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2010-6123","authenticated-orcid":false,"given":"Karla L.","family":"Silva-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Instituto Tecnol\u00f3gico Superior de Tantoyuca, Tecnol\u00f3gico Nacional de M\u00e9xico, Tantoyuca 92100, VER, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4941-9123","authenticated-orcid":false,"given":"Jos\u00e9 A.","family":"Rosado-Aguilar","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Yucatan, M\u00e9rida 97000, YUC, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Hern\u00e1ndez-Vidal","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, Gral. Escobedo 66054, NL, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s13071-020-04499-z","article-title":"New World Screwworm (Cochliomyia hominivorax) Myiasis in Feral Swine of Uruguay: One Health and Transboundary Disease Implications","volume":"14","author":"Altuna","year":"2021","journal-title":"Parasites Vectors"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1111\/tbed.13113","article-title":"Epidemiological Analysis of the New World Screwworm (Cochliomyia hominivorax) in Ecuador","volume":"66","author":"Arciniegas","year":"2019","journal-title":"Transbound. Emerg. Dis."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/eea.12607","article-title":"Review of Research Advances in the Screwworm Eradication Program over the Past 25 Years","volume":"164","author":"Scott","year":"2017","journal-title":"Entomol. Exp. Appl."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/vms3.370","article-title":"Cutaneous Myiasis in Cats and Dogs: Cases, Predisposing Conditions and Risk Factors","volume":"7","author":"Pezzi","year":"2021","journal-title":"Vet. Med. Sci."},{"key":"ref_5","first-page":"101220","article-title":"Estimation the Reinvasion of New World Screwworm (Cochliomyia hominivorax) in Central America: The Role of Animal Movement in Disease Dispersal and Control Measures","volume":"59","year":"2025","journal-title":"Vet. Parasitol. Reg. Stud. Rep."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Vargas-Ter\u00e1n, M., Spradbery, J.P., Hofmann, H.C., and Tweddle, N.E. (2020). Impact of Screwworm Eradication Programmes Using the Sterile Insect Technique. Sterile Insect Tech, CRC Press.","DOI":"10.1201\/9781003035572-29"},{"key":"ref_7","first-page":"e974","article-title":"Historical Perspective and New Avenues to Control the Myiasis-Causing Cochliomyia hominivorax Fly in Uruguay","volume":"25","author":"Fresia","year":"2021","journal-title":"Agrociencia Urug."},{"key":"ref_8","first-page":"92","article-title":"Insectos y \u00c1caros de Mayor Importancia en la Producci\u00f3n Bovina Nacional. An\u00e1lisis del Impacto de la Miasis Por Cochliomyia hominivorax Sobre la Producci\u00f3n Ganadera en Argentina","volume":"2","author":"Signorini","year":"2022","journal-title":"Rev. IDIA"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1590\/S1984-29612014042","article-title":"Reavalia\u00e7\u00e3o do Potencial Impacto Econ\u00f4mico de Parasitos de Bovinos No Brasil","volume":"23","author":"Grisi","year":"2014","journal-title":"Rev. Bras. Parasitol. Vet."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Rodriguez-Vivas, R.I., Cutolo, A.A., Barros, A.T.M.d., Cuore, U.D., Molento, M.B., L\u00f3pez-Osorio, S., Rodrigues, D.S., Spina, M., Borges, F.A., and Lopes, W.D.Z. (2026). Management Practices for the Control of Haematobia irritans, Dermatobia hominis, and Cochliomyia hominivorax in Cattle Across Latin America: A Sustainable, Collective Approach. Pathogens, 15.","DOI":"10.3390\/pathogens15020177"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1749-6632.2000.tb05289.x","article-title":"Screwworm Eradication in the Americas","volume":"916","author":"Wyss","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_12","first-page":"e94039","article-title":"The New World Screwworm in the United States: A Narrative Review Anchored to the 2025 Travel-Associated Human Case","volume":"17","author":"Hailu","year":"2025","journal-title":"Cureus"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1365-2915.2008.00788.x","article-title":"Molecular Characterization of Esterase E3 Gene Associated with Organophosphorus Insecticide Resistance in the New World Screwworm Fly, Cochliomyia hominivorax","volume":"23","author":"Carvalho","year":"2009","journal-title":"Med. Vet. Entomol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.vetpar.2010.02.029","article-title":"Changes in the Frequency of the G137D and W251S Mutations in the Carboxylesterase E3 Gene of Cochliomyia hominivorax (Diptera: Calliphoridae) Populations from Uruguay","volume":"170","author":"Limia","year":"2010","journal-title":"Vet. Parasitol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.vetpar.2010.11.017","article-title":"Acetylcholinesterase CDNA Sequencing and Identification of Mutations Associated with Organophosphate Resistance in Cochliomyia hominivorax (Diptera: Calliphoridae)","volume":"177","year":"2011","journal-title":"Vet. Parasitol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"110384","DOI":"10.1016\/j.vetpar.2024.110384","article-title":"Failure of Doramectin and Ivermectin in Preventing Cochliomyia hominivorax Myiasis in a Subtropical Region: A Pharmacokinetic-Pharmacodynamic Study","volume":"334","author":"Muchiut","year":"2025","journal-title":"Vet. Parasitol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"100410","DOI":"10.1016\/j.emcon.2024.100410","article-title":"A Comprehensive Review on Environmental and Human Health Impacts of Chemical Pesticide Usage","volume":"11","author":"Zhou","year":"2025","journal-title":"Emerg. Contam."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"117432","DOI":"10.1016\/j.envres.2023.117432","article-title":"Present Status of Insecticide Impacts and Eco-Friendly Approaches for Remediation\u2014A Review","volume":"240","author":"Barathi","year":"2024","journal-title":"Environ. Res."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Ansari, M.S., Moraiet, M.A., and Ahmad, S. (2014). Insecticides: Impact on the Environment and Human Health. Environmental Deterioration and Human Health, Springer.","DOI":"10.1007\/978-94-007-7890-0_6"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2174\/157019312800604733","article-title":"Natural Product Pesticides: Their Development, Delivery and Use Against Insect Vectors","volume":"9","author":"Mann","year":"2012","journal-title":"Mini. Rev. Org. Chem."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1080\/09670874.2022.2046889","article-title":"Rosmarinus officinalis as a Natural Insecticide: A Review","volume":"70","author":"Jahanian","year":"2024","journal-title":"Int. J. Pest Manag."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/07352680802053908","article-title":"Phytochemicals and Insect Control: An Antifeedant Approach","volume":"27","author":"Koul","year":"2008","journal-title":"Crit. Rev. Plant Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.sajb.2016.03.010","article-title":"Plant Extracts to Control Ticks of Veterinary and Medical Importance: A Review","volume":"105","author":"Adenubi","year":"2016","journal-title":"S. Afr. J. Bot."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Gutierrez-Rodriguez, S.M., Cordova-Guerreo, I., Diaz-Rubio, L., Davila-Barboza, J.A., Rodriguez-Sanchez, I.P., Lopez-Monroy, B., Galindo-Rodriguez, S.A., and Flores, A.E. (2026). Oviposition Deterrent and Larvicidal Activity of Salvia munzii Essential Oil Against Susceptible and Insecticide-Resistant Aedes aegypti. Trop. Med. Infect. Dis., 11.","DOI":"10.3390\/tropicalmed11050134"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Senthil-Nathan, S. (2020). A Review of Resistance Mechanisms of Synthetic Insecticides and Botanicals, Phytochemicals, and Essential Oils as Alternative Larvicidal Agents Against Mosquitoes. Front. Physiol., 10.","DOI":"10.3389\/fphys.2019.01591"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s00436-024-08118-z","article-title":"Chemical Composition of Four Essential Oils and Their Adulticidal, Repellence, and Field Oviposition Deterrence Activities against Culex pipiens L. (Diptera: Culicidae)","volume":"123","author":"Farag","year":"2024","journal-title":"Parasitol. Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.indcrop.2014.09.052","article-title":"Activities of Apiaceae Essential Oils and Volatile Compounds on Hatchability, Development, Reproduction and Nutrition of Pseudaletia unipuncta (Lepidoptera: Noctuidae)","volume":"63","author":"Sousa","year":"2015","journal-title":"Ind. Crops Prod."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1590\/s1984-296120180015","article-title":"In Vitro Efficacy of Essential Oils with Different Concentrations of 1,8-Cineole against Rhipicephalus (Boophilus) microplus","volume":"27","author":"Canuto","year":"2018","journal-title":"Rev. Bras. Parasitol. Veterin\u00e1ria"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1510186","DOI":"10.1155\/joch\/1510186","article-title":"Bin Biomimetic and Synthetic Advances in Natural Pesticides: Balancing Efficiency and Environmental Safety","volume":"2025","author":"Imran","year":"2025","journal-title":"J. Chem."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Vlaiculescu, A., and Varrone, C. (2022). Sustainable and Eco-Friendly Alternatives to Reduce the Use of Pesticides. Pesticides in the Natural Environment, Elsevier.","DOI":"10.1016\/B978-0-323-90489-6.00014-8"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/ejss.12755","article-title":"How Green Alternatives to Chemical Pesticides Are Environmentally Friendly and More Efficient","volume":"70","author":"Huang","year":"2019","journal-title":"Eur. J. Soil Sci."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Souto, A.L., Sylvestre, M., T\u00f6lke, E.D., Tavares, J.F., Barbosa-Filho, J.M., and Cebri\u00e1n-Torrej\u00f3n, G. (2021). Plant-Derived Pesticides as an Alternative to Pest Management and Sustainable Agricultural Production: Prospects, Applications and Challenges. Molecules, 26.","DOI":"10.3390\/molecules26164835"},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Kaspute, G., Ivaskiene, T., Ramanavicius, A., Ramanavicius, S., and Prentice, U. (2025). Terpenes and Essential Oils in Pharmaceutics: Applications as Therapeutic Agents and Penetration Enhancers with Advanced Delivery Systems for Improved Stability and Bioavailability. Pharmaceutics, 17.","DOI":"10.3390\/pharmaceutics17060793"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s10311-020-01142-2","article-title":"Nanoemulsions of Essential Oils to Improve Solubility, Stability and Permeability: A Review","volume":"19","author":"Barradas","year":"2020","journal-title":"Environ. Chem. Lett."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00425-025-04788-w","article-title":"Enhancing Essential Oils: Advanced Extraction, Sustainability, and Nanotechnology for Optimal Use","volume":"262","author":"Kaspute","year":"2025","journal-title":"Planta"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"110506","DOI":"10.1016\/j.vetpar.2025.110506","article-title":"Nanocarriers of Natural and Synthetic Ixodicides, New Alternatives against Rhipicephalus microplus (Acari: Ixodidae): A Review","volume":"337","author":"Vidal","year":"2025","journal-title":"Vet. Parasitol."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Kumar, A., Singh, P., Gupta, V., and Prakash, B. (2020). Application of Nanotechnology to Boost the Functional and Preservative Properties of Essential Oils. Functional and Preservative Properties of Phytochemicals, Academic Press.","DOI":"10.1016\/B978-0-12-818593-3.00008-7"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"630","DOI":"10.2174\/1573413719666230718122527","article-title":"Recent Advances in the Nanotechnology-Based Applications of Essential Oils","volume":"20","author":"Zhang","year":"2023","journal-title":"Curr. Nanosci."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1080\/17425247.2016.1182487","article-title":"Plant Extracts: From Encapsulation to Application","volume":"13","author":"Zafar","year":"2016","journal-title":"Expert Opin. Drug Deliv."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Lammari, N., Louaer, O., Meniai, A.H., and Elaissari, A. (2020). Encapsulation of Essential Oils via Nanoprecipitation Process: Overview, Progress, Challenges and Prospects. Pharmaceutics, 12.","DOI":"10.3390\/pharmaceutics12050431"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Bayraktar, O., Erdogan, I., K\u00f6se, M.D., and Kalmaz, G. (2017). Nanocarriers for Plant-Derived Natural Compounds. Nanostructures for Antimicrobial Therapy, Elsevier.","DOI":"10.1016\/B978-0-323-46152-8.00017-2"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Dias, G.F., Vieira, A.C.F., Paiva-Santos, A.C., Veiga, F., and Costa, G. (Phytochem. Rev., 2026). Plant-Derived Bioactive Compounds in Nanocarrier Systems for Dermatological Applications, Phytochem. Rev., in press.","DOI":"10.1007\/s11101-026-10249-3"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"4251091","DOI":"10.1155\/ijbm\/4251091","article-title":"Topical Delivery Systems for Plant-Derived Antimicrobial Agents: A Review of Current Advances","volume":"2025","author":"Hashempur","year":"2025","journal-title":"Int. J. Biomater."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"135","DOI":"10.4155\/tde-2023-0116","article-title":"Lipid-Based Nanocarriers for Enhanced Delivery of Plant-Derived Bioactive Molecules: A Comprehensive Review","volume":"15","author":"Kothapalli","year":"2024","journal-title":"Ther. Deliv."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Ranjbar, S., Emamjomeh, A., Sharifi, F., Zarepour, A., Aghaabbasi, K., Dehshahri, A., Sepahvand, A.M., Zarrabi, A., Beyzaei, H., and Zahedi, M.M. (2023). Lipid-Based Delivery Systems for Flavonoids and Flavonolignans: Liposomes, Nanoemulsions, and Solid Lipid Nanoparticles. Pharmaceutics, 15.","DOI":"10.3390\/pharmaceutics15071944"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Bidyarani, N., Jaiswal, J., and Kumar, U. (2023). Botanicals-Based Nanoformulations for the Management of Insect-Pests. Nanophytopathology, CRC Press.","DOI":"10.1201\/9781003344513-13"},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-Ponce, R., Flores-Suarez, A.E., Hern\u00e1ndez-Escare\u00f1o, J.J., Vidal, G.H., Villarreal, J.P.V., and Garc\u00eda, L.H.D. (2025). Phytotherapeutic Alternatives: New Nanotechnology-Based Approaches to Tick Control. Natural Alternatives and Nanotechnology Applied to the One Health Approach, Springer.","DOI":"10.1007\/978-3-032-03675-9_9"},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Luneja, R.L., and Mkindi, A.G. (2025). Advances in Botanical-Based Nanoformulations for Sustainable Cotton Insect Pest Management in Developing Countries. Front. Agron., 7.","DOI":"10.3389\/fagro.2025.1558395"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10340-024-01846-2","article-title":"Innovative Formulation Strategies for Botanical- and Essential Oil-Based Insecticides","volume":"98","author":"Sarmah","year":"2024","journal-title":"J. Pest Sci."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Page, M.J., McKenzie, J.E., Bossuyt, P.M., Boutron, I., Hoffmann, T.C., Mulrow, C.D., Shamseer, L., Tetzlaff, J.M., Akl, E.A., and Brennan, S.E. (2021). The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews. PLoS Med., 18.","DOI":"10.1371\/journal.pmed.1003583"},{"key":"ref_51","first-page":"1400","article-title":"Problem\u00e1tica del gusano barrenador del ganado, Cochliomyia hominivorax (Coquerel, 1858) en Colombia","volume":"13","author":"Forero","year":"2008","journal-title":"Rev. MVZ Cordoba"},{"key":"ref_52","first-page":"69","article-title":"Miasis Por Cochliomyia hominivorax","volume":"2018","author":"Castells","year":"2018","journal-title":"XLVI Jorn. Urug. Buiat."},{"key":"ref_53","unstructured":"World Organisation for Animal Health (2019). Miasis Por Cochliomyia hominvorax y Miasis por Chrysomya bezziana. Manual Terrestre de la OIE 2019, World Organisation for Animal Health."},{"key":"ref_54","unstructured":"World Organisation for Animal Health (2026, June 16). Miasis por Cochliomyia hominivorax\u2014OMSA\u2014Organizaci\u00f3n Mundial de Sanidad Animal. Available online: https:\/\/www.woah.org\/es\/enfermedad\/miasis-por-cochliomyia-hominivorax\/."},{"key":"ref_55","unstructured":"World Health Organization (WHO) (2026, June 16). Miasis por Larvas de Cochliomyia hominivorax\u2014OPS\/OMS, Organizaci\u00f3n Panamericana de La Salud. Available online: https:\/\/www.paho.org\/es\/temas\/miasis-por-larvas-cochliomyia-hominivorax."},{"key":"ref_56","unstructured":"Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA) (2026, June 16). Miasis por Gusano Barrenador. Available online: https:\/\/www.gob.mx\/senasica\/documentos\/miasis-por-gusano-barrenador?state=published."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Akhoundi, M., Mathieu, A., Hannachi, W., Nasrallah, J., Quezel, G., Blaizot, R., Blanchet, D., Ben Romdhane, H., Epelboin, L., and Izri, A. (2023). Morphological and Molecular Characterizations of Cochliomyia hominivorax (Diptera: Calliphoridae) Larvae Responsible for Wound Myiasis in French Guiana. Diagnostics, 13.","DOI":"10.3390\/diagnostics13152575"},{"key":"ref_58","unstructured":"Center for Food Security & Public Health (2026, June 16). Myiasis Caused by Old and New World Screwworms. Available online: https:\/\/www.cfsph.iastate.edu\/Factsheets\/pdfs\/screwworm_myiasis.pdf."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-Coronado, P.L., Rosales Mart\u00ednez, F., Zarate Trivi\u00f1o, D., Monroy Hernandez, R., Torres Ram\u00edrez, J.C., Mendez-Zamora, G., Hern\u00e1ndez Mart\u00ednez, S.P., Kawas, J.R., Rodr\u00edguez Padilla, C., and Ramos Zayas, Y. (2026). Natural Occurrence of Cochliomyia hominivorax Myiasis in Surgically Treated Cattle under Different Macrocyclic Lactone Regimens: Implications for Animal Welfare and Surveillance. Front. Anim. Sci., 7.","DOI":"10.3389\/fanim.2026.1839332"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.vetpar.2006.04.010","article-title":"A Survey of Mutations in the Cochliomyia hominivorax (Diptera: Calliphoridae) Esterase E3 Gene Associated with Organophosphate Resistance and the Molecular Identification of Mutant Alleles","volume":"140","author":"Torres","year":"2006","journal-title":"Vet. Parasitol."},{"key":"ref_61","unstructured":"(2026, June 16). Food and Drug Administration Resistencia Antiparasitaria. FDA, Available online: https:\/\/www.fda.gov\/animal-veterinary\/safety-health\/resistencia-antiparasitaria."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Rants\u2019o, T.A., Koekemoer, L.L., Panayides, J.L., and van Zyl, R.L. (2022). Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review. Molecules, 27.","DOI":"10.3390\/molecules27207026"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Dhifi, W., Bellili, S., Jazi, S., Bahloul, N., and Mnif, W. (2016). Essential Oils\u2019 Chemical Characterization and Investigation of Some Biological Activities: A Critical Review. Medicines, 3.","DOI":"10.3390\/medicines3040025"},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Abbas, M.G., Haris, A., Binyameen, M., Nazir, A., Moz\u016bratis, R., and Azeem, M. (2022). Chemical Composition, Larvicidal and Repellent Activities of Wild Plant Essential Oils against Aedes aegypti. Biology, 12.","DOI":"10.3390\/biology12010008"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"de Sousa dos Santos, E.L.V., Cruz, J.N., da Costa, G.V., de S\u00e1, E.M.F., da Silva, A.K.P., Fernandes, C.P., de Faria Mota Oliveira, A.E.M., Duarte, J.L., Bezerra, R.M., and Tavares, J.F. (2024). Essential Oil of Ocimum basilicum against Aedes aegypti and Culex quinquefasciatus: Larvicidal Activity of a Nanoemulsion and In Silico Study. Separations, 11.","DOI":"10.3390\/separations11040097"},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Hern\u00e1ndez-Dom\u00ednguez, J.M., Gonz\u00e1lez-Gardu\u00f1o, R., Castro-Saines, E., Lagunes-Quintanilla, R., Rodr\u00edguez-Vivas, R.I., Olmedo-Ju\u00e1rez, A., Cortes-Morales, J.A., and Le\u00f3n-Gonz\u00e1lez, C.Y. (2026). Acaricidal Effect of Essential Oils in the Control of Rhipicephalus microplus and Amblyomma mixtum Larvae in Mexico. Pathogens, 15.","DOI":"10.3390\/pathogens15040403"},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Selles, S.M.A., Kouidri, M., Gonz\u00e1lez, M.G., Gonz\u00e1lez, J., S\u00e1nchez, M., Gonz\u00e1lez-Coloma, A., Sanchis, J., Elhachimi, L., Sonia Olmeda, A., and Tercero, J.M. (2021). Acaricidal and Repellent Effects of Essential Oils against Ticks: A Review. Pathogens, 10.","DOI":"10.3390\/pathogens10111379"},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Jankowska, M., Rogalska, J., Wyszkowska, J., and Stankiewicz, M. (2017). Molecular Targets for Components of Essential Oils in the Insect Nervous System\u2014A Review. Molecules, 23.","DOI":"10.3390\/molecules23010034"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.3390\/agriengineering6020068","article-title":"An Overview of the Mechanisms of Action and Administration Technologies of the Essential Oils Used as Green Insecticides","volume":"6","author":"Popescu","year":"2024","journal-title":"AgriEngineering"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"110020","DOI":"10.1016\/j.vetpar.2023.110020","article-title":"Larvicidal Activity in Vitro of Essential Oils against Cochliomyia hominivorax","volume":"322","author":"Medeiros","year":"2023","journal-title":"Vet. Parasitol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.exppara.2016.05.010","article-title":"Ethnobotanical Knowledge on Botanical Repellents Employed in the African Region against Mosquito Vectors\u2014A Review","volume":"167","author":"Pavela","year":"2016","journal-title":"Exp. Parasitol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.vetpar.2009.11.022","article-title":"Acaricidal Activity of Extracts from Petiveria alliacea (Phytolaccaceae) against the Cattle Tick, Rhipicephalus (Boophilus) microplus (Acari: Ixodidae)","volume":"168","year":"2010","journal-title":"Vet. Parasitol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"18918","DOI":"10.1007\/s11356-021-12841-w","article-title":"Essential Oils and Their Bioactive Compounds as Eco-Friendly Novel Green Pesticides for Management of Storage Insect Pests: Prospects and Retrospects","volume":"28","author":"Chaudhari","year":"2021","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Gupta, I., Singh, R., Muthusamy, S., Sharma, M., Grewal, K., Singh, H.P., and Batish, D.R. (2023). Plant Essential Oils as Biopesticides: Applications, Mechanisms, Innovations, and Constraints. Plants, 12.","DOI":"10.3390\/plants12162916"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1080\/09670874.2021.1982067","article-title":"Monoterpenes: Chemistry, Insecticidal Activity against Stored Product Insects and Modes of Action\u2014A Review","volume":"70","author":"Abdelgaleil","year":"2024","journal-title":"Int. J. Pest Manag."},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Yap, P.S.X., Yusoff, K., Lim, S.H.E., Chong, C.M., and Lai, K.S. (2021). Membrane Disruption Properties of Essential Oils\u2014A Double-Edged Sword?. Processes, 9.","DOI":"10.3390\/pr9040595"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s42690-020-00272-y","article-title":"Impact of Essential Oils on Musca domestica Larvae: Oxidative Stress and Antioxidant Responses","volume":"41","author":"Chintalchere","year":"2020","journal-title":"Int. J. Trop. Insect Sci."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"6860271","DOI":"10.1155\/2018\/6860271","article-title":"Essential Oils as Repellents against Arthropods","volume":"2018","author":"Lee","year":"2018","journal-title":"BioMed Res. Int."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.biortech.2009.07.048","article-title":"Repellent Activity of Essential Oils: A Review","volume":"101","author":"Nerio","year":"2010","journal-title":"Bioresour. Technol."},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Ayll\u00f3n-Guti\u00e9rrez, R., D\u00edaz-Rubio, L., Monta\u00f1o-Soto, M., Haro-V\u00e1zquez Mdel, P., and C\u00f3rdova-Guerrero, I. (2024). Applications of Plant Essential Oils in Pest Control and Their Encapsulation for Controlled Release: A Review. Agriculture, 14.","DOI":"10.3390\/agriculture14101766"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"100601","DOI":"10.1016\/j.coesh.2025.100601","article-title":"Selective Actions of Plant-Based Biorational Insecticides: Molecular Mechanisms and Reduced Risks to Non-Target Organisms","volume":"44","author":"Costa","year":"2025","journal-title":"Curr. Opin. Environ. Sci. Health"},{"key":"ref_82","doi-asserted-by":"crossref","unstructured":"Zhu, Y., Wu, T., Hu, Q., He, W., Zheng, Y., Xie, Y., Rao, Q., and Liu, X. (2024). Plant Essential Oils: Dual Action of Toxicity and Egg-Laying Inhibition on Tetranychus urticae (Acari: Tetranychidae), Unveiling Their Potential as Botanical Pesticides. Plants, 13.","DOI":"10.3390\/plants13060763"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1007\/s41348-022-00592-w","article-title":"Insecticidal and Oviposition Deterrent Effects of Five Medicinal Plant Extracts on the Diamondback Moth","volume":"129","author":"Afiunizadeh","year":"2022","journal-title":"J. Plant Dis. Prot."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1080\/07924259.2022.2073277","article-title":"Developmental Inhibitory Effect of the Syzygium aromaticum Essential Oil on the Postembryonic Stages of a Polyphagous Pest, Pericallia ricini (Lepidoptera: Arctiidae)","volume":"66","author":"Sahu","year":"2022","journal-title":"Invertebr. Reprod. Dev."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"24291","DOI":"10.1038\/s41598-021-03819-2","article-title":"Impact of Cymbopogon flexuosus (Poaceae) Essential Oil and Primary Components on the Eclosion and Larval Development of Aedes aegypti","volume":"11","author":"Serrano","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.pestbp.2018.10.002","article-title":"Insecticide Activity of Curcuma longa (Leaves) Essential Oil and Its Major Compound \u03b1-Phellandrene against Lucilia cuprina Larvae (Diptera: Calliphoridae): Histological and Ultrastructural Biomarkers Assessment","volume":"153","author":"Chaaban","year":"2019","journal-title":"Pestic. Biochem. Physiol."},{"key":"ref_87","first-page":"2047","article-title":"Cymbopogon citratus Essential Oil-Induced Ultrastructural & Morphological Changes in the Midgut, Cuticle & Haller\u2019s Organ of the Tick Haemaphysalis longicornis (Acari: Ixodidae)","volume":"25","author":"Agwunobi","year":"2020","journal-title":"Syst. Appl. Acarol."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1080\/01650424.2020.1871025","article-title":"Biochemical and Histopathological Effect of the Essential Oil of Citrus sinensis (L.) Osbeck on Larvae of Culex pipiens Linnaeus, 1758 (Diptera: Culicidae)","volume":"42","author":"Azmy","year":"2021","journal-title":"Aquat. Insects"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4103\/0019-5154.31924","article-title":"Larvicidal Efficacy of Essential Oil of Betel Leaf (Piper Betle) on the Larvae of the Old World Screwworm Fly, Chrysomya bezziana in Vitro","volume":"52","author":"Wardhana","year":"2007","journal-title":"Indian J. Dermatol."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/EJMP\/2017\/32078","article-title":"Chemical Composition of the Essential Oil of Tagetes minuta and Its Activity against Cochliomyia macellaria (Diptera: Calliphoridae)","volume":"18","author":"Chaaban","year":"2017","journal-title":"Eur. J. Med. Plants"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.exppara.2019.01.013","article-title":"Tissue Damage and Cytotoxic Effects of Tagetes minuta Essential Oil against Lucilia cuprina","volume":"198","author":"Chaaban","year":"2019","journal-title":"Exp. Parasitol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/10412905.2017.1423406","article-title":"Chemical Composition of Piper gaudichaudianum Essential Oil and Its Bioactivity against Lucilia cuprina (Diptera: Calliphoridae)","volume":"30","author":"Chaaban","year":"2018","journal-title":"J. Essent. Oil Res."},{"key":"ref_93","doi-asserted-by":"crossref","unstructured":"Bedini, S., Guarino, S., Echeverria, M.C., Flamini, G., Ascrizzi, R., Loni, A., and Conti, B. (2020). Allium sativum, Rosmarinus officinalis, and Salvia officinalis Essential Oils: A Spiced Shield against Blowflies. Insects, 11.","DOI":"10.3390\/insects11030143"},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Bedini, S., Flamini, G., Cosci, F., Ascrizzi, R., Echeverria, M.C., Gomez, E.V., Guidi, L., Landi, M., Lucchi, A., and Conti, B. (2019). Toxicity and Oviposition Deterrence of Essential Oils of Clinopodium nubigenum and Lavandula angustifolia against the Myiasis-Inducing Blowfly Lucilia sericata. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0212576"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1080\/07924259.2021.2016508","article-title":"Effect of Lantana camara Essential Oil on Embryogenesis and Postembryonic Development of the Blowfly, Chrysomya megacephala (Diptera: Calliphoridae) Following Egg Treatment","volume":"66","author":"Maddheshiya","year":"2022","journal-title":"Invertebr. Reprod. Dev."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/jvec.12310","article-title":"Potential of Essential Oils to Prevent Fly Strike and Their Effects on the Longevity of Adult Lucilia sericata","volume":"43","author":"Khater","year":"2018","journal-title":"J. Vector Ecol."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/ijd.13828","article-title":"Toxicity and Growth Inhibition Potential of Vetiver, Cinnamon, and Lavender Essential Oils and Their Blends against Larvae of the Sheep Blowfly, Lucilia sericata","volume":"57","author":"Khater","year":"2018","journal-title":"Int. J. Dermatol."},{"key":"ref_98","doi-asserted-by":"crossref","unstructured":"Bedini, S., Farina, P., Napoli, E., Flamini, G., Ascrizzi, R., Verzera, A., Conti, B., and Zappal\u00e0, L. (2021). Bioactivity of Different Chemotypes of Oregano Essential Oil against the Blowfly Calliphora vomitoria Vector of Foodborne Pathogens. Insects, 12.","DOI":"10.3390\/insects12010052"},{"key":"ref_99","first-page":"100024","article-title":"Evaluation of Essential Oils and Diluents against Chrysomya megacephala, an Important Mechanical Vector","volume":"3","author":"Ramos","year":"2023","journal-title":"J. Nat. Pestic. Res."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.indcrop.2019.02.030","article-title":"Essential Oil from Curcuma longa Leaves: Can an Overlooked by-Product from Turmeric Industry Be Effective for Myiasis Control?","volume":"132","author":"Chaaban","year":"2019","journal-title":"Ind. Crops Prod."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1080\/14786419.2017.1392947","article-title":"Insecticide Activity of Baccharis dracunculifolia Essential Oil against Cochliomyia macellaria (Diptera: Calliphoridae)","volume":"32","author":"Chaaban","year":"2018","journal-title":"Nat. Prod. Res."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1007\/s12639-015-0715-8","article-title":"Larvicidal Activity of Camphor and Lavender Oils against Sheep Blowfly, Lucilia sericata (Diptera: Calliphoridae)","volume":"40","author":"Shalaby","year":"2015","journal-title":"J. Parasit. Dis."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1365-4632.2010.04656.x","article-title":"Control of the Myiasis-Producing Fly, Lucilia sericata, with Egyptian Essential Oils","volume":"50","author":"Khater","year":"2011","journal-title":"Int. J. Dermatol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/s13071-017-2006-y","article-title":"Artemisia Spp. Essential Oils against the Disease-Carrying Blowfly Calliphora vomitoria","volume":"10","author":"Bedini","year":"2017","journal-title":"Parasites Vectors"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s00436-013-3688-5","article-title":"Bioactivities of Some Essential Oils against the Camel Nasal Botfly, Cephalopina titillator","volume":"113","author":"Khater","year":"2014","journal-title":"Parasitol. Res."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"080002","DOI":"10.1063\/5.0032223","article-title":"Benefits and Limitations in Using Biopesticides: A Review","volume":"2313","author":"Essiedu","year":"2020","journal-title":"AIP Conf. Proc."},{"key":"ref_107","doi-asserted-by":"crossref","unstructured":"Devrnja, N., Milutinovi\u0107, M., and Savi\u0107, J. (2022). When Scent Becomes a Weapon\u2014Plant Essential Oils as Potent Bioinsecticides. Sustainability, 14.","DOI":"10.3390\/su14116847"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.tplants.2016.10.005","article-title":"Essential Oils as Ecofriendly Biopesticides? Challenges and Constraints","volume":"21","author":"Pavela","year":"2016","journal-title":"Trends Plant Sci."},{"key":"ref_109","first-page":"679","article-title":"Application of Botanical Pesticides in Organic Agriculture Production: Potential and Challenges","volume":"59","author":"Toan","year":"2021","journal-title":"Vietnam J. Sci. Technol."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1002\/anie.200802585","article-title":"Nanomedicine\u2014Challenge and Perspectives","volume":"48","author":"Riehemann","year":"2009","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_111","doi-asserted-by":"crossref","unstructured":"Yusuf, A., Almotairy, A.R.Z., Henidi, H., Alshehri, O.Y., and Aldughaim, M.S. (2023). Nanoparticles as Drug Delivery Systems: A Review of the Implication of Nanoparticles\u2019 Physicochemical Properties on Responses in Biological Systems. Polymers, 15.","DOI":"10.3390\/polym15071596"},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"Lagarrigue, P., Moncalvo, F., and Cellesi, F. (2022). Non-Spherical Polymeric Nanocarriers for Therapeutics: The Effect of Shape on Biological Systems and Drug Delivery Properties. Pharmaceutics, 15.","DOI":"10.3390\/pharmaceutics15010032"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"119722","DOI":"10.1016\/j.envres.2024.119722","article-title":"Prospects and Challenges of Nanopesticides in Advancing Pest Management for Sustainable Agricultural and Environmental Service","volume":"261","author":"Zainab","year":"2024","journal-title":"Environ. Res."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"26777","DOI":"10.1039\/D0RA03491F","article-title":"A Brief Review on Solid Lipid Nanoparticles: Part and Parcel of Contemporary Drug Delivery Systems","volume":"10","author":"Duan","year":"2020","journal-title":"RSC Adv."},{"key":"ref_115","first-page":"1","article-title":"An Update on Nanoemulsions Using Nanosized Liquid in Liquid Colloidal Systems","volume":"Volume 1","author":"Gupta","year":"2019","journal-title":"Nanoemulsions, Properties, Fabrications and Applications"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpharm.2006.10.021","article-title":"Nanoparticles\u2014A Historical Perspective","volume":"331","author":"Kreuter","year":"2007","journal-title":"Int. J. Pharm."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.ijpharm.2008.10.003","article-title":"Lipid Nanoparticles (SLN, NLC) in Cosmetic and Pharmaceutical Dermal Products","volume":"366","author":"Pardeike","year":"2009","journal-title":"Int. J. Pharm."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev-food-030216-025908","article-title":"Edible Nanoemulsions as Carriers of Active Ingredients: A Review","volume":"8","author":"McClements","year":"2017","journal-title":"Annu. Rev. Food Sci. Technol."},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Albuquerque, P.M., Azevedo, S.G., de Andrade, C.P., D\u2019Ambros, N.C.d.S., P\u00e9rez, M.T.M., and Manzato, L. (2022). Biotechnological Applications of Nanoencapsulated Essential Oils: A Review. Polymers, 14.","DOI":"10.3390\/polym14245495"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"102655","DOI":"10.1016\/j.cis.2022.102655","article-title":"Targeted Delivery and Controlled Released of Essential Oils Using Nanoencapsulation: A Review","volume":"303","author":"Weisany","year":"2022","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_121","doi-asserted-by":"crossref","unstructured":"Ojeda-Piedra, S.A., Zambrano-Zaragoza, M.L., Gonz\u00e1lez-Reza, R.M., Garc\u00eda-Betanzos, C.I., Real-Sandoval, S.A., and Quintanar-Guerrero, D. (2022). Nano-Encapsulated Essential Oils as a Preservation Strategy for Meat and Meat Products Storage. Molecules, 27.","DOI":"10.3390\/molecules27238187"},{"key":"ref_122","doi-asserted-by":"crossref","unstructured":"Villarreal-Villarreal, J.P., Garc\u00eda-P\u00e9rez, J.N., Hern\u00e1ndez Escare\u00f1o, J.J., Galindo Rodr\u00edguez, S.A., Heya, M.S., Hern\u00e1ndez Vidal, G., and Garc\u00eda-Ponce, R. (2025). In Vitro Larvicidal Efficacy of a Fipronil-Based Nanoixodicide Against Rhipicephalus microplus. Trop. Med. Infect. Dis., 10.","DOI":"10.3390\/tropicalmed10100284"},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.vetpar.2011.05.028","article-title":"Nanomedicine: Novel Approaches in Human and Veterinary Therapeutics","volume":"180","author":"Irache","year":"2011","journal-title":"Vet. Parasitol."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1007\/s11095-006-0284-8","article-title":"Nanotechnology: Intelligent Design to Treat Complex Disease","volume":"23","author":"Couvreur","year":"2006","journal-title":"Pharm. Res."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"119214","DOI":"10.1016\/j.ijpharm.2020.119214","article-title":"Advances and Challenges in Nanocarriers and Nanomedicines for Veterinary Application","volume":"580","author":"Carvalho","year":"2020","journal-title":"Int. J. Pharm."},{"key":"ref_126","doi-asserted-by":"crossref","unstructured":"Iacob, A.T., Lupascu, F.G., Apotrosoaei, M., Vasincu, I.M., Tauser, R.G., Lupascu, D., Giusca, S.E., Caruntu, I.D., and Profire, L. (2021). Recent Biomedical Approaches for Chitosan Based Materials as Drug Delivery Nanocarriers. Pharmaceutics, 13.","DOI":"10.3390\/pharmaceutics13040587"},{"key":"ref_127","doi-asserted-by":"crossref","unstructured":"Jawadi, Z., Yang, C., Haidar, Z.S., Santa Maria, P.L., and Massa, S. (2022). Bio-Inspired Muco-Adhesive Polymers for Drug Delivery Applications. Polymers, 14.","DOI":"10.3390\/polym14245459"},{"key":"ref_128","first-page":"2604","article-title":"Bioadhesive Nanoparticles as Potent Drug Delivery Carriers","volume":"30","author":"Senyigit","year":"2022","journal-title":"Curr. Med. Chem."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"4631","DOI":"10.2174\/0929867325666181101110050","article-title":"Nanocarriers: A Successful Tool to Increase Solubility, Stability and Optimise Bioefficacy of Natural Constituents","volume":"26","author":"Bilia","year":"2018","journal-title":"Curr. Med. Chem."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s13744-025-01290-6","article-title":"A Review on Novel Formulations and Delivery Systems of Botanical Insecticides for Enhanced Efficacy","volume":"54","author":"Kumar","year":"2025","journal-title":"Neotrop. Entomol."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1016\/j.biotechadv.2014.10.010","article-title":"Application of Nanotechnology for the Encapsulation of Botanical Insecticides for Sustainable Agriculture: Prospects and Promises","volume":"32","author":"Campos","year":"2014","journal-title":"Biotechnol. Adv."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/01480545.2018.1525393","article-title":"Nanoformulations and Their Mode of Action in Insects: A Review of Biological Interactions","volume":"44","author":"Shahzad","year":"2019","journal-title":"Drug Chem. Toxicol."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.aspen.2021.06.006","article-title":"Ovicidal, Larvicidal and Oviposition Repelling Action of a Nanoemulsion of Citronella Essential Oil (Cymbopogon winterianus) on Cochliomyia hominivorax (Diptera: Calliphoridae)","volume":"24","author":"Bricarello","year":"2021","journal-title":"J. Asia. Pac. Entomol."},{"key":"ref_134","first-page":"293","article-title":"Development of Baccharis dracunculifolia (Asteraceae) Essential Oil Nanoemulsion and Its Biological Activity on Pre-Pupae of Cochliomyia hominivorax (Diptera: Calliphoridae)","volume":"7","author":"Seugling","year":"2019","journal-title":"J. Pharm. Pharmacol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"6210","DOI":"10.1080\/14786419.2020.1837809","article-title":"Nanobiopesticides: Development and Inseticidal Activity of Nanoemulsions Containing Lemongrass or Eucalyptus Oils","volume":"35","author":"Velho","year":"2021","journal-title":"Nat. Prod. Res."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.17582\/journal.pjz\/20220418100455","article-title":"Insecticidal Efficacy of Geranium Oil Nanoemulsion and Synergism with Sesame Oil and Their Acetylcholinesterase Inhibition","volume":"56","author":"Aboelhadid","year":"2024","journal-title":"Pak. J. Zool."},{"key":"ref_137","first-page":"2983","article-title":"Low Dose of Nanocapsules Containing Eucalyptus Oil Has Beneficial Repellent Effect Against Horn Fly (Diptera: Muscidae)","volume":"111","author":"Galli","year":"2018","journal-title":"J. Econ. Entomol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/aen.12592","article-title":"Rosmarinus officinalis Essential Oil Incorporated into Nanoparticles as an Efficient Insecticide against Drosophila suzukii (Diptera: Drosophilidae)","volume":"61","author":"Caetano","year":"2022","journal-title":"Aust. Entomol."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1007\/s10340-025-01938-7","article-title":"Insecticidal Activity and Morphophysiological Disturbances of Terpenes and Phenylpropanoids Poly(\u03b5-Caprolactone) Nanoparticles in Drosophila suzukii and Selectivity to Palmistichus elaeisis","volume":"98","author":"Oliveira","year":"2025","journal-title":"J. Pest Sci."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"100062","DOI":"10.1016\/j.plana.2024.100062","article-title":"Interactions of Foliar Nanopesticides with Insect Cuticle Facilitated through Plant Cuticle: Effects of Surface Chemistry and Roughness-Topography-Texture","volume":"7","author":"Arcot","year":"2024","journal-title":"Plant Nano Biol."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1477-3155-12-5","article-title":"Engineered Nanoparticles Interacting with Cells: Size Matters","volume":"12","author":"Shang","year":"2014","journal-title":"J. Nanobiotechnol."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev-bioeng-071811-150124","article-title":"The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems","volume":"14","author":"Albanese","year":"2012","journal-title":"Annu. Rev. Biomed. Eng."},{"key":"ref_143","doi-asserted-by":"crossref","unstructured":"Valdivieso-Ugarte, M., Gomez-Llorente, C., Plaza-D\u00edaz, J., and Gil, \u00c1. (2019). Antimicrobial, Antioxidant, and Immunomodulatory Properties of Essential Oils: A Systematic Review. Nutrients, 11.","DOI":"10.3390\/nu11112786"},{"key":"ref_144","doi-asserted-by":"crossref","unstructured":"de Sousa, D.P., Damasceno, R.O.S., Amorati, R., Elshabrawy, H.A., de Castro, R.D., Bezerra, D.P., Nunes, V.R.V., Gomes, R.C., and Lima, T.C. (2023). Essential Oils: Chemistry and Pharmacological Activities. Biomolecules, 13.","DOI":"10.3390\/biom13071144"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"111586","DOI":"10.1016\/j.fct.2020.111586","article-title":"Oregano (Origanum vulgare L.) Essential Oil Provides Anti-Inflammatory Activity and Facilitates Wound Healing in a Human Keratinocytes Cell Model","volume":"144","author":"Avola","year":"2020","journal-title":"Food Chem. Toxicol."},{"key":"ref_146","doi-asserted-by":"crossref","unstructured":"Hallan, S.S., Ferrara, F., Cortesi, R., and Sguizzato, M. (2025). Potential of the Nano-Encapsulation of Antioxidant Molecules in Wound Healing Applications: An Innovative Strategy to Enhance the Bio-Profile. Molecules, 30.","DOI":"10.3390\/molecules30030641"},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/s40475-021-00233-6","article-title":"Myiasis and Tungiasis","volume":"8","author":"Palencia","year":"2021","journal-title":"Curr. Trop. Med. Rep."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1111\/ijd.15672","article-title":"Cutaneous Myiasis in Skin Cancer and Malignant Wounds: A Systematic Review","volume":"60","author":"Cuestas","year":"2021","journal-title":"Int. J. Dermatol."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.addr.2018.06.009","article-title":"Practical Guidelines for the Characterization and Quality Control of Pure Drug Nanoparticles and Nano-Cocrystals in the Pharmaceutical Industry","volume":"131","author":"Peltonen","year":"2018","journal-title":"Adv. Drug Deliv. Rev."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"93","DOI":"10.2217\/nnm-2018-0120","article-title":"Nanopharmaceuticals and Nanomedicines Currently on the Market: Challenges and Opportunities","volume":"14","author":"Farjadian","year":"2019","journal-title":"Nanomedicine"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1001\/amajethics.2019.347","article-title":"Regulating Nanomedicine at the Food and Drung Administration","volume":"21","author":"Paradise","year":"2019","journal-title":"AMA J. 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