{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T16:03:36Z","timestamp":1782230616074,"version":"3.54.5"},"reference-count":30,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T00:00:00Z","timestamp":1668643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Key Supporting Scientific Research Projects of Beijing Road Medical Sector, General Hospital of Xinjiang Military Region","award":["2022jzbjl16"],"award-info":[{"award-number":["2022jzbjl16"]}]},{"name":"Key Supporting Scientific Research Projects of Beijing Road Medical Sector, General Hospital of Xinjiang Military Region","award":["82102390"],"award-info":[{"award-number":["82102390"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2022jzbjl16"],"award-info":[{"award-number":["2022jzbjl16"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82102390"],"award-info":[{"award-number":["82102390"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomolecules"],"abstract":"<jats:p>Rickettsiales (Rickettsia spp., Ehrlichia spp., and Anaplasma spp., etc.) are generally recognized as potentially emerging tick-borne pathogens. However, some bacteria and areas in China remain uninvestigated. In this study, we collected 113 ticks from mammals in Guizhou Province, Southwest China, and screened for the Rickettsiales bacteria. Subsequently, two spotted fever group Rickettsia species and one Candidatus Lariskella sp. were detected and characterized. \u201cCandidatus Rickettsia jingxinensis\u201d was detected in Rhipicephalus microplus (1\/1), Haemaphysalis flava (1\/3, 33.33%), Haemaphysalis kitaokai (1\/3), and Ixodes sinensis (4\/101, 3.96%), whereas Rickettsia monacensis was positive in H. flava (1\/3), H. kitaokai (2\/3), and I. sinensis ticks (74\/101, 73.27%). At least two variants\/sub-genotypes were identified in the R. monacensis isolates, and the strikingly high prevalence of R. monacensis may suggest a risk of human infection. Unexpectedly, a Candidatus Lariskella sp. belonging to the family Candidatus Midichloriaceae was detected from Ixodes ovatus (1\/4) and I. sinensis (10\/101, 9.90%). The gltA and groEL gene sequences were successfully obtained, and they show the highest (74.63\u201374.89% and 73.31%) similarities to \u201cCandidatus Midichloria mitochondrii\u201d, respectively. Herein, we name the species \u201cCandidatus Lariskella guizhouensis\u201d. These may be the first recovered gltA and groEL sequences of the genus Candidatus Lariskella.<\/jats:p>","DOI":"10.3390\/biom12111701","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T03:35:23Z","timestamp":1668742523000},"page":"1701","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Prevalence of Spotted Fever Group Rickettsia and Candidatus Lariskella in Multiple Tick Species from Guizhou Province, China"],"prefix":"10.3390","volume":"12","author":[{"given":"Miao","family":"Lu","sequence":"first","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping District, Beijing 102206, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Meng","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai\u2019an 271016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Wang","sequence":"additional","affiliation":[{"name":"The Military General Hospital of Xinjiang PLA, Urumqi 830000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhua","family":"Tian","sequence":"additional","affiliation":[{"name":"Wuhan Center for Disease Control and Prevention, Wuhan 430024, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangpeng","family":"Tang","sequence":"additional","affiliation":[{"name":"Guizhou Center for Disease Control and Prevention, Guiyang 550004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0419-1508","authenticated-orcid":false,"given":"Wen","family":"Wang","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping District, Beijing 102206, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Li","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai\u2019an 271016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyao","family":"Li","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai\u2019an 271016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9887-6665","authenticated-orcid":false,"given":"Xiaoyu","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai\u2019an 271016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6971-4541","authenticated-orcid":false,"given":"Yue","family":"Sun","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai\u2019an 271016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyu","family":"Duan","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai\u2019an 271016, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xincheng","family":"Qin","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping District, Beijing 102206, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Li","sequence":"additional","affiliation":[{"name":"National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping District, Beijing 102206, China"},{"name":"Tianjin Key Laboratory of Food and Biotechnology, Tianjin University of Commerce, Beichen District, Tianjin 300134, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3389\/fcimb.2017.00298","article-title":"Emerging tick-borne viruses in the twenty-first century","volume":"7","author":"Mansfield","year":"2017","journal-title":"Front. 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