{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:14:25Z","timestamp":1788909265315,"version":"build-2803163510"},"reference-count":317,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T00:00:00Z","timestamp":1689120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Kathleen Lonsdale Institute for Human Health Research, Maynooth University","award":["SFI-12\/RI\/2346\/3"],"award-info":[{"award-number":["SFI-12\/RI\/2346\/3"]}]},{"name":"Science Foundation Ireland","award":["SFI-12\/RI\/2346\/3"],"award-info":[{"award-number":["SFI-12\/RI\/2346\/3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomolecules"],"abstract":"<jats:p>The progressive degeneration of the skeletal musculature in Duchenne muscular dystrophy is accompanied by reactive myofibrosis, fat substitution, and chronic inflammation. Fibrotic changes and reduced tissue elasticity correlate with the loss in motor function in this X-chromosomal disorder. Thus, although dystrophinopathies are due to primary abnormalities in the DMD gene causing the almost-complete absence of the cytoskeletal Dp427-M isoform of dystrophin in voluntary muscles, the excessive accumulation of extracellular matrix proteins presents a key histopathological hallmark of muscular dystrophy. Animal model research has been instrumental in the characterization of dystrophic muscles and has contributed to a better understanding of the complex pathogenesis of dystrophinopathies, the discovery of new disease biomarkers, and the testing of novel therapeutic strategies. In this article, we review how mass-spectrometry-based proteomics can be used to study changes in key components of the endomysium, perimysium, and epimysium, such as collagens, proteoglycans, matricellular proteins, and adhesion receptors. The mdx-4cv mouse diaphragm displays severe myofibrosis, making it an ideal model system for large-scale surveys of systematic alterations in the matrisome of dystrophic fibers. Novel biomarkers of myofibrosis can now be tested for their appropriateness in the preclinical and clinical setting as diagnostic, pharmacodynamic, prognostic, and\/or therapeutic monitoring indicators.<\/jats:p>","DOI":"10.3390\/biom13071108","type":"journal-article","created":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T01:43:22Z","timestamp":1689212602000},"page":"1108","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Extracellular Matrix Proteomics: The mdx-4cv Mouse Diaphragm as a Surrogate for Studying Myofibrosis in Dystrophinopathy"],"prefix":"10.3390","volume":"13","author":[{"given":"Paul","family":"Dowling","sequence":"first","affiliation":[{"name":"Department of Biology, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Co. Kildare, Ireland"},{"name":"Kathleen Lonsdale Institute for Human Health Research, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Co. Kildare, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Gargan","sequence":"additional","affiliation":[{"name":"Department of Biology, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Co. Kildare, Ireland"},{"name":"Kathleen Lonsdale Institute for Human Health Research, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Co. Kildare, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margit","family":"Zweyer","sequence":"additional","affiliation":[{"name":"Department of Neonatology and Paediatric Intensive Care, Children\u2019s Hospital, German Center for Neurodegenerative Diseases, University of Bonn, D53127 Bonn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0923-7090","authenticated-orcid":false,"given":"Dieter","family":"Swandulla","sequence":"additional","affiliation":[{"name":"Institute of Physiology, Medical Faculty, University of Bonn, D53115 Bonn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6266-4510","authenticated-orcid":false,"given":"Kay","family":"Ohlendieck","sequence":"additional","affiliation":[{"name":"Department of Biology, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Co. Kildare, Ireland"},{"name":"Kathleen Lonsdale Institute for Human Health Research, Maynooth University, National University of Ireland, W23 F2H6 Maynooth, Co. Kildare, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s42826-022-00128-1","article-title":"Role of animal models in biomedical research: A review","volume":"38","author":"Mukherjee","year":"2022","journal-title":"Lab. Anim. Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41572-021-00248-3","article-title":"Duchenne muscular dystrophy","volume":"7","author":"Duan","year":"2021","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1242\/dmm.018424","article-title":"Animal models of Duchenne muscular dystrophy: From basic mechanisms to gene therapy","volume":"8","author":"McGreevy","year":"2015","journal-title":"Dis. Model. Mech."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"C409","DOI":"10.1152\/ajpcell.00212.2021","article-title":"Murine models of Duchenne muscular dystrophy: Is there a best model?","volume":"321","author":"Swiderski","year":"2021","journal-title":"Am. J. Physiol.-Cell Physiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.nmd.2022.04.005","article-title":"Pig models for Duchenne muscular dystrophy\u2014From disease mechanisms to validation of new diagnostic and therapeutic concepts","volume":"32","author":"Stirm","year":"2022","journal-title":"Neuromuscul. Disord."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1002\/jcsm.13103","article-title":"Cellular interplay in skeletal muscle regeneration and wasting: Insights from animal models","volume":"14","author":"Henrot","year":"2023","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/nrd4467","article-title":"Muscle wasting in disease: Molecular mechanisms and promising therapies","volume":"14","author":"Cohen","year":"2015","journal-title":"Nat. Rev. Drug Discov."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/s41586-020-2938-9","article-title":"Fibrosis: From mechanisms to medicines","volume":"587","author":"Henderson","year":"2020","journal-title":"Nature"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Antar, S.A., Ashour, N.A., Marawan, M.E., and Al-Karmalawy, A.A. (2023). Fibrosis: Types, Effects, Markers, Mechanisms for Disease Progression, and Its Relation with Oxidative Stress, Immunity, and Inflammation. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24044004"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s00441-018-2955-2","article-title":"Skeletal muscle fibrosis: An overview","volume":"375","author":"Mahdy","year":"2019","journal-title":"Cell Tissue Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.matbio.2018.01.014","article-title":"Regulation of fibrosis in muscular dystrophy","volume":"68\u201369","author":"Smith","year":"2018","journal-title":"Matrix Biol."},{"key":"ref_12","first-page":"348","article-title":"Collagen VI disorders: Insights on form and function in the extracellular matrix and beyond","volume":"71\u201372","author":"Bateman","year":"2018","journal-title":"Matrix Biol."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Zanotti, S., Magri, F., Salani, S., Napoli, L., Ripolone, M., Ronchi, D., Fortunato, F., Ciscato, P., Velardo, D., and D\u2019Angelo, M.G. (2023). Extracellular Matrix Disorganization and Sarcolemmal Alterations in COL6-Related Myopathy Patients with New Variants of COL6 Genes. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24065551"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"633","DOI":"10.3233\/JND-200577","article-title":"Clinical and Molecular Spectrum Associated with COL6A3 c.7447A>G p.(Lys2483Glu) Variant: Elucidating its Role in Collagen VI-related Myopathies","volume":"8","author":"Donkervoort","year":"2021","journal-title":"J. Neuromuscul. Dis."},{"key":"ref_15","first-page":"184","article-title":"The role of fibrosis in Duchenne muscular dystrophy","volume":"31","author":"Klingler","year":"2012","journal-title":"Acta Myol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"965631","DOI":"10.1155\/2014\/965631","article-title":"Understanding the process of fibrosis in Duchenne muscular dystrophy","volume":"2014","author":"Kharraz","year":"2014","journal-title":"Biomed. Res. Int."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00292-017-0265-1","article-title":"Molecular pathogenesis of Duchenne muscular dystrophy-related fibrosis","volume":"38","author":"Ohlendieck","year":"2017","journal-title":"Pathologe"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"3879","DOI":"10.1111\/febs.15466","article-title":"The discovery of dystrophin, the protein product of the Duchenne muscular dystrophy gene","volume":"287","author":"Hoffman","year":"2020","journal-title":"FEBS J."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1007\/s00424-021-02623-1","article-title":"Complexity of skeletal muscle degeneration: Multi-systems pathophysiology and organ crosstalk in dystrophinopathy","volume":"473","author":"Ohlendieck","year":"2021","journal-title":"Pfl\u00fcgers Arch."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Dowling, P., Gargan, S., Murphy, S., Zweyer, M., Sabir, H., Swandulla, D., and Ohlendieck, K. (2021). The Dystrophin Node as Integrator of Cytoskeletal Organization, Lateral Force Transmission, Fiber Stability and Cellular Signaling in Skeletal Muscle. Proteomes, 9.","DOI":"10.3390\/proteomes9010009"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1038\/s42003-022-03980-y","article-title":"The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction","volume":"5","author":"Wilson","year":"2022","journal-title":"Commun. Biol."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Zab\u0142ocka, B., G\u00f3recki, D.C., and Zab\u0142ocki, K. (2021). Disrupted Calcium Homeostasis in Duchenne Muscular Dystrophy: A Common Mechanism behind Diverse Consequences. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms222011040"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"e2200003","DOI":"10.1002\/pmic.202200003","article-title":"Proteomic profiling of impaired excitation-contraction coupling and abnormal calcium handling in muscular dystrophy","volume":"22","author":"Dowling","year":"2022","journal-title":"Proteomics"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Dubinin, M.V., and Belosludtsev, K.N. (2023). Ion Channels of the Sarcolemma and Intracellular Organelles in Duchenne Muscular Dystrophy: A Role in the Dysregulation of Ion Homeostasis and a Possible Target for Therapy. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24032229"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"299rv4","DOI":"10.1126\/scitranslmed.aaa7322","article-title":"Immune-mediated pathology in Duchenne muscular dystrophy","volume":"7","author":"Rosenberg","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.semcdb.2016.09.013","article-title":"Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications","volume":"64","author":"Serrano","year":"2017","journal-title":"Semin. Cell Dev. Biol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/cphy.c170052","article-title":"Immunobiology of Inherited Muscular Dystrophies","volume":"8","author":"Tidball","year":"2018","journal-title":"Compr. Physiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"102332","DOI":"10.1016\/j.coph.2022.102332","article-title":"Update on anti-fibrotic pharmacotherapies in skeletal muscle disease","volume":"68","author":"Muraine","year":"2023","journal-title":"Curr. Opin. Pharmacol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/978-1-0716-1382-5_24","article-title":"Mouse Models of Muscle Fibrosis","volume":"2299","author":"Serrano","year":"2021","journal-title":"Methods Mol. Biol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/jmor.21088","article-title":"Diversity of extracellular matrix morphology in vertebrate skeletal muscle","volume":"281","author":"Sleboda","year":"2020","journal-title":"J. Morphol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3389\/fphys.2020.00495","article-title":"The Structure and Role of Intramuscular Connective Tissue in Muscle Function","volume":"11","author":"Purslow","year":"2020","journal-title":"Front. Physiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1056523","DOI":"10.3389\/fcell.2022.1056523","article-title":"Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche","volume":"10","author":"Liu","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.33594\/000000196","article-title":"Control of Muscle Fibro-Adipogenic Progenitors by Myogenic Lineage is Altered in Aging and Duchenne Muscular Dystrophy","volume":"53","author":"Moratal","year":"2019","journal-title":"Cell. Physiol. Biochem."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"210110","DOI":"10.1098\/rsob.210110","article-title":"Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases","volume":"11","author":"Molina","year":"2021","journal-title":"Open Biol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"6484","DOI":"10.1111\/febs.16080","article-title":"Signaling pathways regulating the fate of fibro\/adipogenic progenitors (FAPs) in skeletal muscle regeneration and disease","volume":"289","author":"Giuliani","year":"2022","journal-title":"FEBS J."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1093\/hmg\/5.8.1149","article-title":"Differential expression of dystrophin isoforms in strains of mdx mice with different mutations","volume":"5","author":"Im","year":"1996","journal-title":"Hum. Mol. Genet."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/pmic.201500158","article-title":"Pathoproteomic profiling of the skeletal muscle matrisome in dystrophinopathy associated myofibrosis","volume":"16","author":"Holland","year":"2016","journal-title":"Proteomics"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1073\/pnas.81.4.1189","article-title":"X chromosome-linked muscular dystrophy (mdx) in the mouse","volume":"81","author":"Bulfield","year":"1984","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF00687043","article-title":"Skeletal muscle pathology in X chromosome-linked muscular dystrophy (mdx) mouse","volume":"69","author":"Tanabe","year":"1986","journal-title":"Acta Neuropathol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"4177","DOI":"10.1111\/febs.12267","article-title":"The mdx mouse model as a surrogate for Duchenne muscular dystrophy","volume":"280","author":"Partridge","year":"2013","journal-title":"FEBS J."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1073\/pnas.86.4.1292","article-title":"Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice","volume":"86","author":"Chapman","year":"1989","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0960-8966(01)00301-7","article-title":"DMD(mdx3Cv) and DMD(mdx4Cv) dystrophin mutations in mice: Rapid polymerase chain reaction genotyping","volume":"12","year":"2002","journal-title":"Neuromuscul. Disord."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1002\/mus.21700","article-title":"Sequencing protocols to genotype mdx, mdx(4cv), and mdx(5cv) mice","volume":"42","author":"Banks","year":"2010","journal-title":"Muscle Nerve"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/mus.21873","article-title":"Genotyping mdx, mdx3cv, and mdx4cv mice by primer competition polymerase chain reaction","volume":"43","author":"Shin","year":"2011","journal-title":"Muscle Nerve"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1203\/00006450-199207000-00025","article-title":"The frequency of revertants in mdx mouse genetic models for Duchenne muscular dystrophy","volume":"32","author":"Danko","year":"1992","journal-title":"Pediatr. Res."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Gutpell, K.M., Hrinivich, W.T., and Hoffman, L.M. (2015). Skeletal muscle fibrosis in the mdx\/utrn+\/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0117306"},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Giovarelli, M., Arnaboldi, F., Zecchini, S., Cornaghi, L.B., Nava, A., Sommariva, M., Clementi, E.G.I., and Gagliano, N. (2022). Characterisation of Progressive Skeletal Muscle Fibrosis in the Mdx Mouse Model of Duchenne Muscular Dystrophy: An In Vivo and In Vitro Study. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23158735"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s10735-022-10109-2","article-title":"Duchenne muscular dystrophy progression induced by downhill running is accompanied by increased endomysial fibrosis and oxidative damage DNA in muscle of mdx mice","volume":"54","author":"Lazzarin","year":"2023","journal-title":"J. Mol. Histol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/352536a0","article-title":"The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy","volume":"352","author":"Stedman","year":"1991","journal-title":"Nature"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1152\/japplphysiol.00248.2021","article-title":"Diaphragm muscle fibrosis involves changes in collagen organization with mechanical implications in Duchenne muscular dystrophy","volume":"132","author":"Sahani","year":"2022","journal-title":"J. Appl. Physiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"100131","DOI":"10.1016\/j.mbplus.2023.100131","article-title":"The extracellular matrix of dystrophic mouse diaphragm accounts for the majority of its passive stiffness and is resistant to collagenase digestion","volume":"18","author":"Wohlgemuth","year":"2023","journal-title":"Matrix Biol. Plus."},{"key":"ref_52","first-page":"101","article-title":"Histopathology of Duchenne muscular dystrophy in correlation with changes in proteomic biomarkers","volume":"37","author":"Zweyer","year":"2022","journal-title":"Histol. Histopathol."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Dubuisson, N., Versele, R., Planchon, C., Selvais, C.M., Noel, L., Abou-Samra, M., and Davis-L\u00f3pez de Carrizosa, M.A. (2022). Histological Methods to Assess Skeletal Muscle Degeneration and Regeneration in Duchenne Muscular Dystrophy. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms232416080"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1097\/NEN.0b013e3181aa31c2","article-title":"Endomysial fibrosis in Duchenne muscular dystrophy: A marker of poor outcome associated with macrophage alternative activation","volume":"68","author":"Desguerre","year":"2009","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Gargan, S., Dowling, P., Zweyer, M., Henry, M., Meleady, P., Swandulla, D., and Ohlendieck, K. (2022). Proteomic Identification of Markers of Membrane Repair, Regeneration and Fibrosis in the Aged and Dystrophic Diaphragm. Life, 12.","DOI":"10.3390\/life12111679"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"100062","DOI":"10.1016\/j.mcpro.2021.100062","article-title":"Reflections on the HUPO Human Proteome Project, the Flagship Project of the Human Proteome Organization, at 10 Years","volume":"20","author":"Omenn","year":"2021","journal-title":"Mol. Cell. Proteom."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1021\/acs.jproteome.2c00498","article-title":"The 2022 Report on the Human Proteome from the HUPO Human Proteome Project","volume":"22","author":"Omenn","year":"2022","journal-title":"J. Proteome Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1038\/nature13319","article-title":"Mass-spectrometry-based draft of the human proteome","volume":"509","author":"Wilhelm","year":"2014","journal-title":"Nature"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/nature13302","article-title":"A draft map of the human proteome","volume":"509","author":"Kim","year":"2014","journal-title":"Nature"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"5301","DOI":"10.1038\/s41467-020-19045-9","article-title":"A high-stringency blueprint of the human proteome","volume":"11","author":"Adhikari","year":"2020","journal-title":"Nat. Commun."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1074\/mcp.M700304-MCP200","article-title":"Characterization of the human skeletal muscle proteome by one-dimensional gel electrophoresis and HPLC-ESI-MS\/MS","volume":"7","author":"Yi","year":"2008","journal-title":"Mol. Cell. Proteom."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.1021\/pr800873q","article-title":"Characterization of human skeletal muscle biopsy samples using shotgun proteomics","volume":"8","author":"Parker","year":"2009","journal-title":"J. Proteome Res."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1080\/14789450.2017.1364996","article-title":"Mapping the human skeletal muscle proteome: Progress and potential","volume":"14","author":"Capitanio","year":"2017","journal-title":"Expert Rev. Proteom."},{"key":"ref_64","first-page":"239","article-title":"Fiber type diversity in skeletal muscle explored by mass spectrometry-based single fiber proteomics","volume":"35","author":"Schiaffino","year":"2020","journal-title":"Histol. Histopathol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s13395-021-00279-0","article-title":"Protein profile of fiber types in human skeletal muscle: A single-fiber proteomics study","volume":"11","author":"Murgia","year":"2021","journal-title":"Skelet. Muscle"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/978-1-0716-2831-7_20","article-title":"Identification of Subproteomic Markers for Skeletal Muscle Profiling","volume":"2596","author":"Dowling","year":"2023","journal-title":"Methods Mol. Biol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/bs.ctm.2015.06.001","article-title":"Applying Proteomics to Investigate Extracellular Matrix in Health and Disease","volume":"76","author":"Randles","year":"2015","journal-title":"Curr. Top. Membr."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1042\/EBC20190001","article-title":"Exploring the extracellular matrix in health and disease using proteomics","volume":"63","author":"Taha","year":"2019","journal-title":"Essays Biochem."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"100528","DOI":"10.1016\/j.mcpro.2023.100528","article-title":"Ten Years of Extracellular Matrix Proteomics: Accomplishments, Challenges, and Future Perspectives","volume":"22","author":"Naba","year":"2023","journal-title":"Mol. Cell. Proteom."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"a004903","DOI":"10.1101\/cshperspect.a004903","article-title":"Overview of the matrisome\u2014An inventory of extracellular matrix constituents and functions","volume":"4","author":"Hynes","year":"2012","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.matbio.2015.06.003","article-title":"The extracellular matrix: Tools and insights for the \u201comics\u201d era","volume":"49","author":"Naba","year":"2016","journal-title":"Matrix Biol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"D1136","DOI":"10.1093\/nar\/gkz849","article-title":"MatrisomeDB: The ECM-protein knowledge database","volume":"48","author":"Shao","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"D1519","DOI":"10.1093\/nar\/gkac1009","article-title":"MatrisomeDB 2.0: 2023 updates to the ECM-protein knowledge database","volume":"51","author":"Shao","year":"2023","journal-title":"Nucleic Acids Res."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"3979","DOI":"10.1042\/BCJ20160686","article-title":"Comparative proteomic assessment of matrisome enrichment methodologies","volume":"473","author":"Krasny","year":"2016","journal-title":"Biochem. J."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1080\/14789450.2021.1984885","article-title":"Advances in the proteomic profiling of the matrisome and adhesome","volume":"18","author":"Krasny","year":"2021","journal-title":"Expert Rev. Proteom."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"104397","DOI":"10.1016\/j.jprot.2021.104397","article-title":"Comparison of extracellular matrix enrichment protocols for the improved characterization of the skin matrisome by mass spectrometry","volume":"251","author":"Dussoyer","year":"2022","journal-title":"J. Proteom."},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Ercan, H., Resch, U., Hsu, F., Mitulovic, G., Bileck, A., Gerner, C., Yang, J.W., Geiger, M., Miller, I., and Zellner, M. (2023). A Practical and Analytical Comparative Study of Gel-Based Top-Down and Gel-Free Bottom-Up Proteomics Including Unbiased Proteoform Detection. Cells, 12.","DOI":"10.3390\/cells12050747"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jprot.2018.02.008","article-title":"Application of targeted mass spectrometry in bottom-up proteomics for systems biology research","volume":"189","author":"Manes","year":"2018","journal-title":"J. Proteom."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/978-1-0716-2831-7_2","article-title":"Top-Down Proteomics and Comparative 2D-DIGE Analysis","volume":"2596","author":"Ohlendieck","year":"2023","journal-title":"Methods Mol. Biol."},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Dowling, P., Gargan, S., Swandulla, D., and Ohlendieck, K. (2023). Fiber-Type Shifting in Sarcopenia of Old Age: Proteomic Profiling of the Contractile Apparatus of Skeletal Muscles. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24032415"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/s42003-023-04635-2","article-title":"Uncovering biology by single-cell proteomics","volume":"6","author":"Mansuri","year":"2023","journal-title":"Commun. Biol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1080\/14789450.2016.1209416","article-title":"Proteomic profiling of muscle fibre type shifting in neuromuscular diseases","volume":"13","author":"Dowling","year":"2016","journal-title":"Expert Rev. Proteom."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"4060","DOI":"10.1021\/acs.jproteome.7b00433","article-title":"Evaluation of FASP, SP3, and iST Protocols for Proteomic Sample Preparation in the Low Microgram Range","volume":"16","author":"Sielaff","year":"2017","journal-title":"J. Proteome Res."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"5674","DOI":"10.1021\/pr900748n","article-title":"Combination of FASP and StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome","volume":"8","author":"Zougman","year":"2009","journal-title":"J. Proteome Res."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"e2200070","DOI":"10.1002\/pmic.202200070","article-title":"Advances in proteomics sample preparation and enrichment for phosphorylation and glycosylation analysis","volume":"22","author":"Xie","year":"2022","journal-title":"Proteomics"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/nmeth.1322","article-title":"Universal sample preparation method for proteome analysis","volume":"6","author":"Zougman","year":"2009","journal-title":"Nat. Methods"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.aca.2019.08.032","article-title":"Filter Aided Sample Preparation\u2014A tutorial","volume":"1090","year":"2019","journal-title":"Anal. Chim. Acta"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/978-1-4939-6747-6_2","article-title":"Improving Proteome Coverage and Sample Recovery with Enhanced FASP (eFASP) for Quantitative Proteomic Experiments","volume":"1550","author":"Erde","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/nmeth.2834","article-title":"Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells","volume":"11","author":"Kulak","year":"2014","journal-title":"Nat. Methods"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1021\/acs.jproteome.0c00890","article-title":"Simple and Efficient Microsolid-Phase Extraction Tip-Based Sample Preparation Workflow to Enable Sensitive Proteomic Profiling of Limited Samples (200 to 10,000 Cells)","volume":"20","author":"Kostas","year":"2021","journal-title":"J. Proteome Res."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/s41596-018-0082-x","article-title":"Single-pot, solid-phase-enhanced sample preparation for proteomics experiments","volume":"14","author":"Hughes","year":"2019","journal-title":"Nat. Protoc."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1021\/acs.jproteome.9b00217","article-title":"Universal Solid-Phase Protein Preparation (USP3) for Bottom-up and Top-down Proteomics","volume":"18","author":"Dagley","year":"2019","journal-title":"J. Proteome Res."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1038\/s41596-022-00727-1","article-title":"High-throughput proteomic sample preparation using pressure cycling technology","volume":"17","author":"Cai","year":"2022","journal-title":"Nat. Protoc."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1021\/acs.jproteome.8b00197","article-title":"Surfactant and Chaotropic Agent Assisted Sequential Extraction\/On-Pellet Digestion (SCAD) for Enhanced Proteomics","volume":"17","author":"Ma","year":"2018","journal-title":"J. Proteome Res."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1074\/mcp.TIR119.001616","article-title":"Sample Preparation by Easy Extraction and Digestion (SPEED)\u2014A Universal, Rapid, and Detergent-free Protocol for Proteomics Based on Acid Extraction","volume":"19","author":"Doellinger","year":"2020","journal-title":"Mol. Cell. Proteom."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"100196","DOI":"10.1016\/j.xpro.2020.100196","article-title":"Protocol for the Bottom-Up Proteomic Analysis of Mouse Spleen","volume":"1","author":"Dowling","year":"2020","journal-title":"STAR Protoc."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ab.2017.11.022","article-title":"Proteomic profiling of large myofibrillar proteins from dried and long-term stored polyacrylamide gels","volume":"543","author":"Murphy","year":"2018","journal-title":"Anal. Biochem."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jchromb.2019.01.031","article-title":"Beneficial effects of Coomassie staining on proteomic analysis employing PAGE separation followed with whole-gel slicing, in-gel digestion and quantitative LC-MS\/MS","volume":"1110\u20131111","author":"Jin","year":"2019","journal-title":"J. Chromatogr. B Analyt. Technol. Biomed. Life Sci."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1021\/acs.jproteome.2c00180","article-title":"1DE-MS Profiling for Proteoform-Correlated Proteomic Analysis, by Combining SDS-PAGE, Whole-Gel Slicing, Quantitative LC-MS\/MS, and Reconstruction of Gel Distributions of Several Thousands of Proteins","volume":"21","author":"Chen","year":"2022","journal-title":"J. Proteome Res."},{"key":"ref_100","doi-asserted-by":"crossref","unstructured":"Dowling, P., Zweyer, M., Swandulla, D., and Ohlendieck, K. (2019). Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics. Proteomes, 7.","DOI":"10.3390\/proteomes7020025"},{"key":"ref_101","doi-asserted-by":"crossref","unstructured":"Zhan, X., Li, B., Zhan, X., Schl\u00fcter, H., Jungblut, P.R., and Coorssen, J.R. (2019). Innovating the Concept and Practice of Two-Dimensional Gel Electrophoresis in the Analysis of Proteomes at the Proteoform Level. Proteomes, 7.","DOI":"10.3390\/proteomes7040036"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1002\/elps.202200257","article-title":"Quantitative assessment confirms deep proteome analysis by integrative top-down proteomics","volume":"44","author":"Carbonara","year":"2023","journal-title":"Electrophoresis"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/prca.201400119","article-title":"State of the art of 2D DIGE","volume":"9","author":"Arentz","year":"2015","journal-title":"Proteom. Clin. Appl."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/978-1-4939-8793-1_20","article-title":"Two-Dimensional Difference Gel Electrophoresis","volume":"1855","author":"Blundon","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/978-1-0716-2831-7_11","article-title":"Comparative 3-Sample 2D-DIGE Analysis of Skeletal Muscles","volume":"2596","author":"Ohlendieck","year":"2023","journal-title":"Methods Mol. Biol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"M111.014647","DOI":"10.1074\/mcp.M111.014647","article-title":"The matrisome: In silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices","volume":"11","author":"Naba","year":"2012","journal-title":"Mol. Cell. Proteom."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1074\/mcp.M114.045260","article-title":"Quantification of extracellular matrix proteins from a rat lung scaffold to provide a molecular readout for tissue engineering","volume":"14","author":"Hill","year":"2015","journal-title":"Mol. Cell. Proteom."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"819","DOI":"10.15252\/msb.20156123","article-title":"Time- and compartment-resolved proteome profiling of the extracellular niche in lung injury and repair","volume":"11","author":"Schiller","year":"2015","journal-title":"Mol. Syst. Biol."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/s41592-019-0391-1","article-title":"A photocleavable surfactant for top-down proteomics","volume":"16","author":"Brown","year":"2019","journal-title":"Nat. Methods"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"15693","DOI":"10.1021\/acs.analchem.0c03104","article-title":"Photocleavable Surfactant-Enabled Extracellular Matrix Proteomics","volume":"92","author":"Knott","year":"2020","journal-title":"Anal. Chem."},{"key":"ref_111","first-page":"3675","article-title":"Decellularization of tissues and organs","volume":"27","author":"Gilbert","year":"2006","journal-title":"Biomaterials"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"14933","DOI":"10.1038\/s41598-019-49575-2","article-title":"The impact of decellularization methods on extracellular matrix derived hydrogels","volume":"9","author":"Ahearne","year":"2019","journal-title":"Sci. Rep."},{"key":"ref_113","doi-asserted-by":"crossref","unstructured":"Mendibil, U., Ruiz-Hernandez, R., Retegi-Carrion, S., Garcia-Urquia, N., Olalde-Graells, B., and Abarrategi, A. (2020). Tissue-Specific Decellularization Methods: Rationale and Strategies to Achieve Regenerative Compounds. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21155447"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1126\/science.1124619","article-title":"Mass spectrometry and protein analysis","volume":"312","author":"Domon","year":"2006","journal-title":"Science"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1021\/cr3003533","article-title":"Protein analysis by shotgun\/bottom-up proteomics","volume":"113","author":"Zhang","year":"2013","journal-title":"Chem. Rev."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1146\/annurev-bioeng-061008-124934","article-title":"Proteomics by mass spectrometry: Approaches, advances, and applications","volume":"11","author":"Yates","year":"2009","journal-title":"Annu. Rev. Biomed. Eng."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"351","DOI":"10.12688\/f1000research.16987.1","article-title":"Recent technical advances in proteomics","volume":"8","author":"Yates","year":"2019","journal-title":"F1000Research"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/nmeth1088","article-title":"Analysis and validation of proteomic data generated by tandem mass spectrometry","volume":"4","author":"Nesvizhskii","year":"2007","journal-title":"Nat. Methods"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.2217\/fmb-2022-0067","article-title":"Matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry in the diagnosis of microorganisms","volume":"17","author":"Evangelista","year":"2022","journal-title":"Future Microbiol."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.copbio.2011.11.014","article-title":"Mass spectrometry-based proteomics for systems biology","volume":"23","author":"Selevsek","year":"2012","journal-title":"Curr. Opin. Biotechnol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"5293","DOI":"10.1021\/pr500880b","article-title":"Isobaric labeling-based relative quantification in shotgun proteomics","volume":"13","author":"Rauniyar","year":"2014","journal-title":"J. Proteome Res."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1039\/D2MO00077F","article-title":"Advances in stable isotope labeling: Dynamic labeling for spatial and temporal proteomic analysis","volume":"18","author":"Beller","year":"2022","journal-title":"Mol. Omics"},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.gpb.2021.08.012","article-title":"Quantitative Proteomics Using Isobaric Labeling: A Practical Guide","volume":"19","author":"Chen","year":"2021","journal-title":"Genom. Proteom. Bioinform."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jpba.2015.04.013","article-title":"Stable isotope labelling methods in mass spectrometry-based quantitative proteomics","volume":"113","author":"Chahrour","year":"2015","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1021\/acs.jafc.6b05835","article-title":"Proteome Analysis Using Isobaric Tags for Relative and Absolute Analysis Quantitation (iTRAQ) Reveals Alterations in Stress-Induced Dysfunctional Chicken Muscle","volume":"65","author":"Xing","year":"2017","journal-title":"J. Agric. Food Chem."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nature19949","article-title":"Mass-spectrometric exploration of proteome structure and function","volume":"537","author":"Aebersold","year":"2016","journal-title":"Nature"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"e1900029","DOI":"10.1002\/pmic.201900029","article-title":"Targeted and Untargeted Proteomics Approaches in Biomarker Development","volume":"20","author":"Sobsey","year":"2020","journal-title":"Proteomics"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.cels.2021.06.006","article-title":"Artificial intelligence for proteomics and biomarker discovery","volume":"12","author":"Mann","year":"2021","journal-title":"Cell Syst."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chroma.2017.10.043","article-title":"Data acquisition workflows in liquid chromatography coupled to high resolution mass spectrometry-based metabolomics: Where do we stand?","volume":"1526","author":"Fenaille","year":"2017","journal-title":"J. Chromatogr. A"},{"key":"ref_130","doi-asserted-by":"crossref","unstructured":"Kitata, R.B., Yang, J.C., and Chen, Y.J. (2022). Advances in data-independent acquisition mass spectrometry towards comprehensive digital proteome landscape. Mass Spectrom. Rev., e21781.","DOI":"10.1002\/mas.21781"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"e5531","DOI":"10.1002\/bmc.5531","article-title":"Is nontargeted data acquisition for target analysis (nDATA) in mass spectrometry a forward-thinking analytical approach?","volume":"37","author":"Abdollahi","year":"2023","journal-title":"Biomed. Chromatogr."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jprot.2018.02.026","article-title":"SWATH mass spectrometry as a tool for quantitative profiling of the matrisome","volume":"189","author":"Krasny","year":"2018","journal-title":"J. Proteom."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1038\/s41467-021-23217-6","article-title":"FKRP-dependent glycosylation of fibronectin regulates muscle pathology in muscular dystrophy","volume":"12","author":"Wood","year":"2021","journal-title":"Nat. Commun."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/978-1-4939-9164-8_14","article-title":"Development and Validation of Multiple Reaction Monitoring (MRM) Assays for Clinical Applications","volume":"1959","author":"Kontostathi","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"15215","DOI":"10.1021\/acs.analchem.2c01975","article-title":"Targeted N-Glycan Analysis with Parallel Reaction Monitoring Using a Quadrupole-Orbitrap Hybrid Mass Spectrometer","volume":"94","author":"Cho","year":"2022","journal-title":"Anal. Chem."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"104775","DOI":"10.1016\/j.jprot.2022.104775","article-title":"A targeted multiplex mass spectrometry method for quantitation of abundant matrix and cellular proteins in formalin-fixed paraffin embedded arterial tissue","volume":"272","author":"Thorsen","year":"2023","journal-title":"J. Proteom."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/978-1-4939-8695-8_11","article-title":"Absolute Protein Quantification Using AQUA-Calibrated 2D-PAGE","volume":"1841","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/mus.22094","article-title":"Structure and function of the skeletal muscle extracellular matrix","volume":"44","author":"Gillies","year":"2011","journal-title":"Muscle Nerve"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"111593","DOI":"10.1016\/j.jbiomech.2023.111593","article-title":"Structure-Function relationships in the skeletal muscle extracellular matrix","volume":"152","author":"Lieber","year":"2023","journal-title":"J. Biomech."},{"key":"ref_140","doi-asserted-by":"crossref","unstructured":"Carbonara, K., Andonovski, M., and Coorssen, J.R. (2021). Proteomes Are of Proteoforms: Embracing the Complexity. Proteomes, 9.","DOI":"10.3390\/proteomes9030038"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"e1800361","DOI":"10.1002\/pmic.201800361","article-title":"Identification and Quantification of Proteoforms by Mass Spectrometry","volume":"19","author":"Schaffer","year":"2019","journal-title":"Proteomics"},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/glycob\/cwx034","article-title":"Biological functions of fucose in mammals","volume":"27","author":"Schneider","year":"2017","journal-title":"Glycobiology"},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1021\/acs.jproteome.5b00767","article-title":"Comprehensive Characterization of Glycosylation and Hydroxylation of Basement Membrane Collagen IV by High-Resolution Mass Spectrometry","volume":"15","author":"Basak","year":"2016","journal-title":"J. Proteome Res."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1479-7364-6-6","article-title":"The human protein disulfide isomerase gene family","volume":"6","author":"Galligan","year":"2012","journal-title":"Hum. Genom."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.matbio.2019.04.002","article-title":"Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasion","volume":"82","author":"Stefanelli","year":"2019","journal-title":"Matrix Biol."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10974-019-09507-z","article-title":"Proteomic profiling of the mouse diaphragm and refined mass spectrometric analysis of the dystrophic phenotype","volume":"40","author":"Murphy","year":"2019","journal-title":"J. Muscle Res. Cell Motil."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/978-3-030-80614-9_4","article-title":"Basic Components of Connective Tissues and Extracellular Matrix: Fibronectin, Fibrinogen, Laminin, Elastin, Fibrillins, Fibulins, Matrilins, Tenascins and Thrombospondins","volume":"1348","author":"Halper","year":"2021","journal-title":"Adv. Exp. Med. Biol."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4161\/cam.22618","article-title":"Laminin-211 in skeletal muscle function","volume":"7","author":"Holmberg","year":"2013","journal-title":"Cell Adhes. Migr."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"154775","DOI":"10.1016\/j.metabol.2021.154775","article-title":"Laminins in metabolic tissues","volume":"120","author":"Goddi","year":"2021","journal-title":"Metabolism"},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.matbio.2016.08.008","article-title":"The role of laminins in the organization and function of neuromuscular junctions","volume":"57\u201358","author":"Rogers","year":"2017","journal-title":"Matrix Biol."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1002\/dneu.20953","article-title":"Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction","volume":"71","author":"Singhal","year":"2011","journal-title":"Dev. Neurobiol."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1242\/jcs.03453","article-title":"Collagens at a glance","volume":"120","author":"Kadler","year":"2007","journal-title":"J. Cell Sci."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ydbio.2015.01.002","article-title":"Hanging on for the ride: Adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and disease","volume":"401","author":"Goody","year":"2015","journal-title":"Dev. Biol."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.actbio.2015.11.009","article-title":"Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin","volume":"30","author":"Grefte","year":"2016","journal-title":"Acta Biomater."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1749-8104-3-24","article-title":"A synaptic nidogen: Developmental regulation and role of nidogen-2 at the neuromuscular junction","volume":"3","author":"Fox","year":"2008","journal-title":"Neural Dev."},{"key":"ref_156","first-page":"a004978","article-title":"The collagen family","volume":"3","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/978-3-030-80614-9_2","article-title":"Basic Structure, Physiology, and Biochemistry of Connective Tissues and Extracellular Matrix Collagens","volume":"1348","author":"Mienaltowski","year":"2021","journal-title":"Adv. Exp. Med. Biol."},{"key":"ref_158","first-page":"3525","article-title":"Collagen VI at a glance","volume":"128","author":"Cescon","year":"2015","journal-title":"J. Cell Sci."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s00401-018-1860-9","article-title":"Collagen VI is required for the structural and functional integrity of the neuromuscular junction","volume":"136","author":"Cescon","year":"2018","journal-title":"Acta Neuropathol."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s13036-022-00292-x","article-title":"Extracellular matrix dynamics: Tracking in biological systems and their implications","volume":"16","author":"Hu","year":"2022","journal-title":"J. Biol. Eng."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/00220345221138525","article-title":"Fibromodulin, a Multifunctional Matricellular Modulator","volume":"102","author":"Zheng","year":"2023","journal-title":"J. Dent. Res."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"e17589","DOI":"10.7554\/eLife.17589","article-title":"Thrombospondin expression in myofibers stabilizes muscle membranes","volume":"5","author":"Vanhoutte","year":"2016","journal-title":"Elife"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s12079-022-00674-2","article-title":"Periostin: An emerging activator of multiple signaling pathways","volume":"16","author":"Wang","year":"2022","journal-title":"J. Cell. Commun. Signal."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"C629","DOI":"10.1152\/ajpcell.00009.2019","article-title":"Integrin signaling: Linking mechanical stimulation to skeletal muscle hypertrophy","volume":"317","author":"Boppart","year":"2019","journal-title":"Am. J. Physiol.-Cell Physiol."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1038\/355696a0","article-title":"Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix","volume":"355","author":"Ervasti","year":"1992","journal-title":"Nature"},{"key":"ref_166","first-page":"1","article-title":"Towards an understanding of the dystrophin-glycoprotein complex: Linkage between the extracellular matrix and the membrane cytoskeleton in muscle fibers","volume":"69","author":"Ohlendieck","year":"1996","journal-title":"Eur. J. Cell Biol."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.csbj.2015.11.002","article-title":"The biochemical and mass spectrometric profiling of the dystrophin complexome from skeletal muscle","volume":"14","author":"Murphy","year":"2015","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"626","DOI":"10.2174\/1389203711209070644","article-title":"The multiple affinities of \u03b1-dystroglycan","volume":"14","author":"Sciandra","year":"2013","journal-title":"Curr. Protein Pept. Sci."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.tibtech.2007.04.002","article-title":"Dystroglycan: A possible mediator for reducing congenital muscular dystrophy?","volume":"25","author":"Sciandra","year":"2007","journal-title":"Trends Biotechnol."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1021\/acs.jproteome.0c00248","article-title":"Comparative Analysis of the Extracellular Matrix Proteome across the Myotendinous Junction","volume":"19","author":"Jacobson","year":"2020","journal-title":"J. Proteome Res."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.matbio.2020.10.004","article-title":"Collagen XII mediated cellular and extracellular mechanisms regulate establishment of tendon structure and function","volume":"95","author":"Izu","year":"2021","journal-title":"Matrix Biol."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"103836","DOI":"10.1016\/j.isci.2022.103836","article-title":"The proteomic profile of the human myotendinous junction","volume":"25","author":"Karlsen","year":"2022","journal-title":"iScience"},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1100\/tsw.2007.92","article-title":"Collagen structure of tendon relates to function","volume":"7","author":"Franchi","year":"2007","journal-title":"Sci. World J."},{"key":"ref_174","doi-asserted-by":"crossref","unstructured":"Croissant, C., Gounou, C., Bouvet, F., Tan, S., and Bouter, A. (2020). Annexin-A6 in Membrane Repair of Human Skeletal Muscle Cell: A Role in the Cap Subdomain. Cells, 9.","DOI":"10.3390\/cells9071742"},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Vidak, E., Javor\u0161ek, U., Vizovi\u0161ek, M., and Turk, B. (2019). Cysteine Cathepsins and their Extracellular Roles: Shaping the Microenvironment. Cells, 8.","DOI":"10.3390\/cells8030264"},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1093\/molbev\/msab081","article-title":"A Comprehensive Phylogenetic Analysis of the Serpin Superfamily","volume":"38","author":"Spence","year":"2021","journal-title":"Mol. Biol. Evol."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s13578-021-00579-4","article-title":"Extracellular matrix: An important regulator of cell functions and skeletal muscle development","volume":"11","author":"Zhang","year":"2021","journal-title":"Cell Biosci."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"D605","DOI":"10.1093\/nar\/gkaa1074","article-title":"The STRING database in 2021: Customizable protein-protein networks, and functional characterization of user-uploaded gene\/measurement sets","volume":"49","author":"Szklarczyk","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1146\/annurev-genom-090314-025003","article-title":"The Pathogenesis and Therapy of Muscular Dystrophies","volume":"16","author":"Guiraud","year":"2015","journal-title":"Annu. Rev. Genom. Hum. Genet."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/s13023-020-01430-8","article-title":"Global epidemiology of Duchenne muscular dystrophy: An updated systematic review and meta-analysis","volume":"15","author":"Crisafulli","year":"2020","journal-title":"Orphanet J. Rare Dis."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/humu.22758","article-title":"The TREAT-NMD DMD Global Database: Analysis of more than 7,000 Duchenne muscular dystrophy mutations","volume":"36","author":"Bladen","year":"2015","journal-title":"Hum. Mutat."},{"key":"ref_182","first-page":"587","article-title":"Early signs of gait deviation in Duchenne muscular dystrophy","volume":"47","author":"Doglio","year":"2011","journal-title":"Eur. J. Phys. Rehabil. Med."},{"key":"ref_183","doi-asserted-by":"crossref","unstructured":"Migliorelli, C., G\u00f3mez-Martinez, M., Sub\u00edas-Beltr\u00e1n, P., Claramunt-Molet, M., Idelsohn-Zielonka, S., Mas-Hurtado, E., Miralles, F., Montolio, M., Rosell\u00f3-Ruano, M., and Medina-Cantillo, J. (2023). Multidimensional Biomechanics-Based Score to Assess Disease Progression in Duchenne Muscular Dystrophy. Sensors, 23.","DOI":"10.3390\/s23020831"},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.gaitpost.2022.12.007","article-title":"Kinematic changes in gait in boys with Duchenne Muscular Dystrophy: Utility of the Gait Deviation Index, the Gait Profile Score and the Gait Variable Scores","volume":"100","author":"Sienko","year":"2023","journal-title":"Gait Posture"},{"key":"ref_185","doi-asserted-by":"crossref","unstructured":"Meyers, T.A., and Townsend, D. (2019). Cardiac Pathophysiology and the Future of Cardiac Therapies in Duchenne Muscular Dystrophy. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20174098"},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.nmd.2018.05.011","article-title":"Imaging the heart to detect cardiomyopathy in Duchenne muscular dystrophy: A review","volume":"28","author":"Power","year":"2018","journal-title":"Neuromuscul. Disord."},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.arbres.2021.01.015","article-title":"Non-Invasive Ventilation for Acute Respiratory Failure in Duchenne Muscular Dystrophy Patients","volume":"57","author":"Vianello","year":"2021","journal-title":"Arch. Bronconeumol."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S2213-2600(21)00581-6","article-title":"Cardiorespiratory management of Duchenne muscular dystrophy: Emerging therapies, neuromuscular genetics, and new clinical challenges","volume":"10","author":"Birnkrant","year":"2022","journal-title":"Lancet Respir. Med."},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1007\/s00198-022-06416-9","article-title":"Reduced bone mineral density in adolescents with Duchenne Muscular Dystrophy (DMD) and scoliosis","volume":"33","author":"Tsaknakis","year":"2022","journal-title":"Osteoporos. Int."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/mus.27464","article-title":"A population-based study of scoliosis among males diagnosed with a dystrophinopathy identified by the Muscular Dystrophy Surveillance, Tracking, and Research Network (MD STARnet)","volume":"65","author":"Conway","year":"2022","journal-title":"Muscle Nerve"},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1007\/s10072-018-3555-3","article-title":"Clinical management of Duchenne muscular dystrophy: The state of the art","volume":"39","author":"Messina","year":"2018","journal-title":"Neurol. Sci."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.neubiorev.2013.03.016","article-title":"Neuropsychological and neurobehavioral functioning in Duchenne muscular dystrophy: A review","volume":"37","author":"Snow","year":"2013","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_193","doi-asserted-by":"crossref","unstructured":"Chieffo, D.P.R., Moriconi, F., Pane, M., Lucibello, S., Ferraroli, E., Norcia, G., Ricci, M., Capasso, A., Cicala, G., and Buchignani, B. (2023). A Longitudinal Follow-Up Study of Intellectual Function in Duchenne Muscular Dystrophy over Age: Is It Really Stable?. J. Clin. Med., 12.","DOI":"10.3390\/jcm12020403"},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/dmcn.15481","article-title":"Global prevalence of intellectual developmental disorder in dystrophinopathies: A systematic review and meta-analysis","volume":"65","year":"2023","journal-title":"Dev. Med. Child Neurol."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S1474-4422(18)30024-3","article-title":"Diagnosis and management of Duchenne muscular dystrophy, part 1: Diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management","volume":"17","author":"Birnkrant","year":"2018","journal-title":"Lancet Neurol."},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S1474-4422(18)30025-5","article-title":"Diagnosis and management of Duchenne muscular dystrophy, part 2: Respiratory, cardiac, bone health, and orthopaedic management","volume":"17","author":"Birnkrant","year":"2018","journal-title":"Lancet Neurol."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S1474-4422(18)30026-7","article-title":"Diagnosis and management of Duchenne muscular dystrophy, part 3: Primary care, emergency management, psychosocial care, and transitions of care across the lifespan","volume":"17","author":"Birnkrant","year":"2018","journal-title":"Lancet Neurol."},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0092-8674(87)90504-6","article-title":"Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals","volume":"50","author":"Koenig","year":"1987","journal-title":"Cell"},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0888-7543(88)90091-2","article-title":"Further studies of gene deletions that cause Duchenne and Becker muscular dystrophies","volume":"2","author":"Forrest","year":"1988","journal-title":"Genomics"},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1093\/oxfordjournals.bmb.a072349","article-title":"Duchenne\/Becker muscular dystrophy: A short overview of the gene, the protein, and current diagnostics","volume":"45","author":"Kunkel","year":"1989","journal-title":"Br. Med. Bull."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/0092-8674(87)90579-4","article-title":"Dystrophin: The protein product of the Duchenne muscular dystrophy locus","volume":"51","author":"Hoffman","year":"1987","journal-title":"Cell"},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0896-6273(88)90191-2","article-title":"Cell and fiber-type distribution of dystrophin","volume":"1","author":"Hoffman","year":"1988","journal-title":"Neuron"},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/0092-8674(88)90065-7","article-title":"Duchenne muscular dystrophy: Deficiency of dystrophin at the muscle cell surface","volume":"54","author":"Bonilla","year":"1988","journal-title":"Cell"},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1212\/WNL.43.4.795","article-title":"Duchenne muscular dystrophy: Deficiency of dystrophin-associated proteins in the sarcolemma","volume":"43","author":"Ohlendieck","year":"1993","journal-title":"Neurology"},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"C241","DOI":"10.1152\/ajpcell.00173.2013","article-title":"Cellular mechanisms of tissue fibrosis. 4. Structural and functional consequences of skeletal muscle fibrosis","volume":"305","author":"Lieber","year":"2013","journal-title":"Am. J. Physiol.-Cell Physiol."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"23249","DOI":"10.18632\/oncotarget.4021","article-title":"Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy","volume":"6","author":"Levi","year":"2015","journal-title":"Oncotarget"},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.lfs.2015.12.015","article-title":"Anti-fibrotic effect of pirfenidone in muscle derived-fibroblasts from Duchenne muscular dystrophy patients","volume":"145","author":"Zanotti","year":"2016","journal-title":"Life Sci."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.2147\/DDDT.S110163","article-title":"Anti-inflammatory drugs for Duchenne muscular dystrophy: Focus on skeletal muscle-releasing factors","volume":"10","author":"Miyatake","year":"2016","journal-title":"Drug Des. Devel. Ther."},{"key":"ref_209","doi-asserted-by":"crossref","unstructured":"March, J.T., Golshirazi, G., Cernisova, V., Carr, H., Leong, Y., Lu-Nguyen, N., and Popplewell, L.J. (2018). Targeting TGF\u03b2 Signaling to Address Fibrosis Using Antisense Oligonucleotides. Biomedicines, 6.","DOI":"10.3390\/biomedicines6030074"},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0959-437X(02)00309-X","article-title":"Muscular dystrophies involving the dystrophin-glycoprotein complex: An overview of current mouse models","volume":"12","author":"Durbeej","year":"2002","journal-title":"Curr. Opin. Genet. Dev."},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"635792","DOI":"10.1155\/2015\/635792","article-title":"Genetic Engineering of Dystroglycan in Animal Models of Muscular Dystrophy","volume":"2015","author":"Sciandra","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1177\/0192623317734823","article-title":"Duchenne and Becker Muscular Dystrophies: A Review of Animal Models, Clinical End Points, and Biomarker Quantification","volume":"45","author":"Wilson","year":"2017","journal-title":"Toxicol. Pathol."},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"dmm043562","DOI":"10.1242\/dmm.043562","article-title":"Mouse models for muscular dystrophies: An overview","volume":"13","author":"Lloyd","year":"2020","journal-title":"Dis. Models Mech."},{"key":"ref_214","doi-asserted-by":"crossref","unstructured":"Sztretye, M., Szab\u00f3, L., Dobrosi, N., Fodor, J., Szentesi, P., Alm\u00e1ssy, J., Magyar, Z.\u00c9., Dienes, B., and Csernoch, L. (2020). From Mice to Humans: An Overview of the Potentials and Limitations of Current Transgenic Mouse Models of Major Muscular Dystrophies and Congenital Myopathies. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21238935"},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/s11248-021-00278-3","article-title":"Animal models for researching approaches to therapy of Duchenne muscular dystrophy","volume":"30","author":"Zaynitdinova","year":"2021","journal-title":"Transgenic Res."},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41536-018-0045-4","article-title":"Humanizing the mdx mouse model of DMD: The long and the short of it","volume":"3","author":"Yucel","year":"2018","journal-title":"NPJ Regen. Med."},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"246195","DOI":"10.1155\/2014\/246195","article-title":"Proteomic profiling of the dystrophin-deficient mdx phenocopy of dystrophinopathy-associated cardiomyopathy","volume":"2014","author":"Holland","year":"2014","journal-title":"Biomed. Res. Int."},{"key":"ref_218","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1002\/pmic.201200578","article-title":"Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin","volume":"13","author":"Holland","year":"2013","journal-title":"Proteomics"},{"key":"ref_219","first-page":"1314","article-title":"Dystrophin-deficient large animal models: Translational research and exon skipping","volume":"7","author":"Yu","year":"2015","journal-title":"Am. J. Transl. Res."},{"key":"ref_220","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13395-017-0124-z","article-title":"The golden retriever model of Duchenne muscular dystrophy","volume":"7","author":"Kornegay","year":"2017","journal-title":"Skelet. Muscle"},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1089\/humc.2015.006","article-title":"Duchenne muscular dystrophy gene therapy in the canine model","volume":"26","author":"Duan","year":"2015","journal-title":"Hum. Gene Ther. Clin. Dev."},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.3727\/096368912X638919","article-title":"Alteration of cardiac progenitor cell potency in GRMD dogs","volume":"21","author":"Cassano","year":"2012","journal-title":"Cell Transpl."},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1002\/pmic.201600002","article-title":"Quantitative proteome profiling of dystrophic dog skeletal muscle reveals a stabilized muscular architecture and protection against oxidative stress after systemic delivery of MuStem cells","volume":"16","author":"Lardenois","year":"2016","journal-title":"Proteomics"},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"101516","DOI":"10.1016\/j.isci.2020.101516","article-title":"Progressive Proteome Changes in the Myocardium of a Pig Model for Duchenne Muscular Dystrophy","volume":"23","author":"Tamiyakul","year":"2020","journal-title":"iScience"},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1038\/s41591-019-0669-y","article-title":"Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy","volume":"25","author":"Regensburger","year":"2019","journal-title":"Nat. Med."},{"key":"ref_226","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/mus.24998","article-title":"Increased collagen cross-linking is a signature of dystrophin-deficient muscle","volume":"54","author":"Smith","year":"2016","journal-title":"Muscle Nerve"},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1002\/mus.880151008","article-title":"Differential expression of muscular dystrophy in diaphragm versus hindlimb muscles of mdx mice","volume":"15","author":"McCarter","year":"1992","journal-title":"Muscle Nerve"},{"key":"ref_228","doi-asserted-by":"crossref","unstructured":"Ritter, P., N\u00fcbler, S., Buttgereit, A., Smith, L.R., M\u00fchlberg, A., Bauer, J., Michael, M., Krei\u00df, L., Haug, M., and Barton, E. (2022). Myofibrillar Lattice Remodeling Is a Structural Cytoskeletal Predictor of Diaphragm Muscle Weakness in a Fibrotic mdx (mdx Cmah-\/-) Model. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms231810841"},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3390\/proteomes3030298","article-title":"Concurrent Label-Free Mass Spectrometric Analysis of Dystrophin Isoform Dp427 and the Myofibrosis Marker Collagen in Crude Extracts from mdx-4cv Skeletal Muscles","volume":"3","author":"Murphy","year":"2015","journal-title":"Proteomes"},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.jprot.2018.01.015","article-title":"Proteomic analysis of the sarcolemma-enriched fraction from dystrophic mdx-4cv skeletal muscle","volume":"191","author":"Murphy","year":"2019","journal-title":"J. Proteom."},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1242\/jcs.02857","article-title":"Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex","volume":"119","author":"Judge","year":"2006","journal-title":"J. Cell Sci."},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"24708","DOI":"10.1038\/srep24708","article-title":"Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation","volume":"6","author":"Arecco","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_233","first-page":"1","article-title":"Ambulatory Duchenne muscular dystrophy children: Cross-sectional correlation between function, quantitative muscle ultrasound and MRI","volume":"41","author":"Abdulhady","year":"2022","journal-title":"Acta Myol."},{"key":"ref_234","doi-asserted-by":"crossref","unstructured":"Peng, F., Xu, H., Song, Y., Xu, K., Li, S., Cai, X., Guo, Y., and Gong, L. (2022). Utilization of T1-Mapping for the pelvic and thigh muscles in Duchenne Muscular Dystrophy: A quantitative biomarker for disease involvement and correlation with clinical assessments. BMC Musculoskelet. Disord., 23.","DOI":"10.1186\/s12891-022-05640-y"},{"key":"ref_235","doi-asserted-by":"crossref","first-page":"e4691","DOI":"10.1002\/nbm.4691","article-title":"Baseline fat fraction is a strong predictor of disease progression in Becker muscular dystrophy","volume":"35","author":"Veeger","year":"2022","journal-title":"NMR Biomed."},{"key":"ref_236","doi-asserted-by":"crossref","first-page":"e2406","DOI":"10.1212\/WNL.0000000000201163","article-title":"Evaluating Genetic Modifiers of Duchenne Muscular Dystrophy Disease Progression Using Modeling and MRI","volume":"99","author":"Barnard","year":"2022","journal-title":"Neurology"},{"key":"ref_237","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/mus.25566","article-title":"A new method of genotyping MDX4CV mice by PCR-RFLP analysis","volume":"56","author":"Tichy","year":"2017","journal-title":"Muscle Nerve"},{"key":"ref_238","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/jgm.1265","article-title":"By-passing the nonsense mutation in the 4 CV mouse model of muscular dystrophy by induced exon skipping","volume":"11","author":"Mitrpant","year":"2009","journal-title":"J. Gene Med."},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1093\/hmg\/ddl082","article-title":"A highly functional mini-dystrophin\/GFP fusion gene for cell and gene therapy studies of Duchenne muscular dystrophy","volume":"15","author":"Li","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"ref_240","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/mt.2009.253","article-title":"Dystrophin delivery to muscles of mdx mice using lentiviral vectors leads to myogenic progenitor targeting and stable gene expression","volume":"18","author":"Kimura","year":"2010","journal-title":"Mol. Ther."},{"key":"ref_241","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.ymthe.2019.01.002","article-title":"Development of Novel Micro-dystrophins with Enhanced Functionality","volume":"27","author":"Ramos","year":"2019","journal-title":"Mol. Ther."},{"key":"ref_242","doi-asserted-by":"crossref","unstructured":"Hersh, J., Condor Capcha, J.M., Iansen Irion, C., Lambert, G., Noguera, M., Singh, M., Kaur, A., Dikici, E., Jim\u00e9nez, J.J., and Shehadeh, L.A. (2021). Peptide-Functionalized Dendrimer Nanocarriers for Targeted Microdystrophin Gene Delivery. Pharmaceutics, 13.","DOI":"10.3390\/pharmaceutics13122159"},{"key":"ref_243","doi-asserted-by":"crossref","first-page":"304","DOI":"10.2174\/1566523223666230407091317","article-title":"Lentiviral micro-dystrophin gene treatment into late-stage mdx mice for Duchene Muscular Dystrophy disease","volume":"23","author":"Eren","year":"2023","journal-title":"Curr. Gene Ther."},{"key":"ref_244","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1093\/hmg\/ddn151","article-title":"Cell-lineage regulated myogenesis for dystrophin replacement: A novel therapeutic approach for treatment of muscular dystrophy","volume":"17","author":"Kimura","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"ref_245","doi-asserted-by":"crossref","first-page":"14025","DOI":"10.1038\/mtm.2014.25","article-title":"Engraftment potential of dermal fibroblasts following in vivo myogenic conversion in immunocompetent dystrophic skeletal muscle","volume":"1","author":"Muir","year":"2014","journal-title":"Mol. Ther. Methods Clin. Dev."},{"key":"ref_246","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ydbio.2014.08.035","article-title":"Extraocular muscle satellite cells are high performance myo-engines retaining efficient regenerative capacity in dystrophin deficiency","volume":"397","author":"Stuelsatz","year":"2015","journal-title":"Dev. Biol."},{"key":"ref_247","doi-asserted-by":"crossref","first-page":"14454","DOI":"10.1038\/ncomms14454","article-title":"Muscle-specific CRISPR\/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy","volume":"8","author":"Bengtsson","year":"2017","journal-title":"Nat. Commun."},{"key":"ref_248","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1038\/s41467-021-23996-y","article-title":"Efficient precise in vivo base editing in adult dystrophic mice","volume":"12","author":"Xu","year":"2021","journal-title":"Nat. Commun."},{"key":"ref_249","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1002\/elps.201800028","article-title":"Comparative gel-based proteomic analysis of chemically crosslinked complexes in dystrophic skeletal muscle","volume":"39","author":"Murphy","year":"2018","journal-title":"Electrophoresis"},{"key":"ref_250","doi-asserted-by":"crossref","first-page":"17","DOI":"10.12688\/hrbopenres.12846.1","article-title":"Chemical crosslinking analysis of \u03b2-dystroglycan in dystrophin-deficient skeletal muscle","volume":"1","author":"Murphy","year":"2018","journal-title":"HRB Open Res."},{"key":"ref_251","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.dib.2018.02.020","article-title":"Subproteomic profiling of sarcolemma from dystrophic mdx-4cv skeletal muscle","volume":"17","author":"Murphy","year":"2018","journal-title":"Data Brief."},{"key":"ref_252","doi-asserted-by":"crossref","unstructured":"Gargan, S., Dowling, P., Zweyer, M., Reimann, J., Henry, M., Meleady, P., Swandulla, D., and Ohlendieck, K. (2021). Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the mdx-4cv Model of Duchenne Muscular Dystrophy. Life, 11.","DOI":"10.3390\/life11070595"},{"key":"ref_253","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jprot.2016.03.011","article-title":"Proteomic analysis of dystrophin deficiency and associated changes in the aged mdx-4cv heart model of dystrophinopathy-related cardiomyopathy","volume":"145","author":"Murphy","year":"2016","journal-title":"J. Proteom."},{"key":"ref_254","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s12014-018-9212-2","article-title":"Proteomic profiling of liver tissue from the mdx-4cv mouse model of Duchenne muscular dystrophy","volume":"15","author":"Murphy","year":"2018","journal-title":"Clin. Proteom."},{"key":"ref_255","doi-asserted-by":"crossref","first-page":"151059","DOI":"10.1016\/j.ejcb.2019.151059","article-title":"Proteomic and cell biological profiling of the renal phenotype of the mdx-4cv mouse model of Duchenne muscular dystrophy","volume":"99","author":"Dowling","year":"2020","journal-title":"Eur. J. Cell Biol."},{"key":"ref_256","doi-asserted-by":"crossref","first-page":"105067","DOI":"10.1016\/j.dib.2019.105067","article-title":"Dataset on the mass spectrometry-based proteomic profiling of the kidney from wild type and the dystrophic mdx-4cv mouse model of X-linked muscular dystrophy","volume":"28","author":"Dowling","year":"2020","journal-title":"Data Brief."},{"key":"ref_257","doi-asserted-by":"crossref","first-page":"101500","DOI":"10.1016\/j.isci.2020.101500","article-title":"Proteome-wide Changes in the mdx-4cv Spleen due to Pathophysiological Cross Talk with Dystrophin-Deficient Skeletal Muscle","volume":"23","author":"Dowling","year":"2020","journal-title":"iScience"},{"key":"ref_258","first-page":"9627","article-title":"Proteomic profiling of the interface between the stomach wall and the pancreas in dystrophinopathy","volume":"31","author":"Dowling","year":"2021","journal-title":"Eur. J. Transl. Myol."},{"key":"ref_259","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12014-015-9099-0","article-title":"Label-free mass spectrometric analysis reveals complex changes in the brain proteome from the mdx-4cv mouse model of Duchenne muscular dystrophy","volume":"12","author":"Murphy","year":"2015","journal-title":"Clin. Proteom."},{"key":"ref_260","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.3892\/ijmm.2017.2952","article-title":"Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy","volume":"39","author":"Murphy","year":"2017","journal-title":"Int. J. Mol. Med."},{"key":"ref_261","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.dib.2018.10.082","article-title":"Dataset on the comparative proteomic profiling of mouse saliva and serum from wild type versus the dystrophic mdx-4cv mouse model of dystrophinopathy","volume":"21","author":"Murphy","year":"2018","journal-title":"Data Brief."},{"key":"ref_262","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1039\/C9MO00182D","article-title":"Identification of marker proteins of muscular dystrophy in the urine proteome from the mdx-4cv model of dystrophinopathy","volume":"16","author":"Gargan","year":"2020","journal-title":"Mol. Omics"},{"key":"ref_263","first-page":"100541","article-title":"Proteomic identification of elevated saliva kallikrein levels in the mdx-4cv mouse model of Duchenne muscular dystrophy","volume":"18","author":"Murphy","year":"2018","journal-title":"Biochem. Biophys. Rep."},{"key":"ref_264","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1016\/j.celrep.2018.10.067","article-title":"A Myogenic Double-Reporter Human Pluripotent Stem Cell Line Allows Prospective Isolation of Skeletal Muscle Progenitors","volume":"25","author":"Wu","year":"2018","journal-title":"Cell Rep."},{"key":"ref_265","doi-asserted-by":"crossref","first-page":"6555","DOI":"10.1038\/s41598-018-24959-y","article-title":"Premyogenic progenitors derived from human pluripotent stem cells expand in floating culture and differentiate into transplantable myogenic progenitors","volume":"8","author":"Narita","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_266","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1002\/stem.1402","article-title":"A new immuno-, dystrophin-deficient model, the NSG-mdx(4Cv) mouse, provides evidence for functional improvement following allogeneic satellite cell transplantation","volume":"31","author":"Arpke","year":"2013","journal-title":"Stem Cells"},{"key":"ref_267","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1186\/s13287-021-02594-1","article-title":"Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR)","volume":"12","author":"Elhussieny","year":"2021","journal-title":"Stem Cell Res. Ther."},{"key":"ref_268","doi-asserted-by":"crossref","first-page":"13120","DOI":"10.1073\/pnas.1615340113","article-title":"Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy","volume":"113","author":"Chang","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_269","doi-asserted-by":"crossref","unstructured":"Ziemba, M., Barkhouse, M., Uaesoontrachoon, K., Giri, M., Hathout, Y., Dang, U.J., Gordish-Dressman, H., Nagaraju, K., and Hoffman, E.P. (2021). Biomarker-focused multi-drug combination therapy and repurposing trial in mdx mice. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0246507"},{"key":"ref_270","doi-asserted-by":"crossref","first-page":"950651","DOI":"10.3389\/fphar.2022.950651","article-title":"Drug development progress in Duchenne muscular dystrophy","volume":"13","author":"Deng","year":"2022","journal-title":"Front. Pharmacol."},{"key":"ref_271","doi-asserted-by":"crossref","unstructured":"Eser, G., and Topalo\u011flu, H. (2022). Current Outline of Exon Skipping Trials in Duchenne Muscular Dystrophy. Genes, 13.","DOI":"10.3390\/genes13071241"},{"key":"ref_272","doi-asserted-by":"crossref","first-page":"833833","DOI":"10.3389\/fbioe.2022.833833","article-title":"A Decade of Progress in Gene Targeted Therapeutic Strategies in Duchenne Muscular Dystrophy: A Systematic Review","volume":"10","author":"Sulaiman","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"ref_273","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1089\/hum.2023.053","article-title":"Crispr-Editing Therapy For Duchenne Muscular Dystrophy","volume":"34","author":"Chemello","year":"2023","journal-title":"Hum. Gene Ther."},{"key":"ref_274","doi-asserted-by":"crossref","first-page":"175675","DOI":"10.1016\/j.ejphar.2023.175675","article-title":"Duchenne muscular dystrophy: Current treatment and emerging exon skipping and gene therapy approach","volume":"947","author":"Patterson","year":"2023","journal-title":"Eur. J. Pharmacol."},{"key":"ref_275","doi-asserted-by":"crossref","unstructured":"Heydemann, A., Bieganski, G., Wachowiak, J., Czarnota, J., Niezgoda, A., Siemionow, K., Ziemiecka, A., Sikorska, M.H., Bozyk, K., and Tullius, S.G. (2023). Dystrophin Expressing Chimeric (DEC) Cell Therapy for Duchenne Muscular Dystrophy: A First-in-Human Study with Minimum 6 Months Follow-up. Stem Cell Rev. Rep.","DOI":"10.1007\/s12015-023-10530-4"},{"key":"ref_276","doi-asserted-by":"crossref","first-page":"2752","DOI":"10.1007\/s00415-019-09481-z","article-title":"Imaging respiratory muscle quality and function in Duchenne muscular dystrophy","volume":"266","author":"Barnard","year":"2019","journal-title":"J. Neurol."},{"key":"ref_277","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.4187\/respcare.07131","article-title":"Impact of Mechanical Ventilation Methods on the Life Perception of Subjects With Duchenne Muscular Dystrophy: French Cross-Sectional Survey","volume":"65","author":"Stalens","year":"2020","journal-title":"Respir. Care"},{"key":"ref_278","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1002\/ppul.25261","article-title":"A systematic review of pharmacologic therapies for the cardiomyopathy of Duchenne muscular dystrophy","volume":"56","author":"Kipke","year":"2021","journal-title":"Pediatr. Pulmonol."},{"key":"ref_279","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.nmd.2019.02.002","article-title":"Respiratory and upper limb function as outcome measures in ambulant and non-ambulant subjects with Duchenne muscular dystrophy: A prospective multicentre study","volume":"29","author":"Ricotti","year":"2019","journal-title":"Neuromuscul. Disord."},{"key":"ref_280","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3233\/JND-180326","article-title":"Echographic Assessment of Diaphragmatic Function in Duchenne Muscular Dystrophy from Childhood to Adulthood","volume":"6","author":"Fayssoil","year":"2019","journal-title":"J. Neuromuscul. Dis."},{"key":"ref_281","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1016\/j.ajpath.2011.07.009","article-title":"mdx(\u2075cv) mice manifest more severe muscle dysfunction and diaphragm force deficits than do mdx Mice","volume":"179","author":"Beastrom","year":"2011","journal-title":"Am. J. Pathol."},{"key":"ref_282","doi-asserted-by":"crossref","first-page":"11317","DOI":"10.3390\/molecules200611317","article-title":"Comparative Label-Free Mass Spectrometric Analysis of Mildly versus Severely Affected mdx Mouse Skeletal Muscles Identifies Annexin, Lamin, and Vimentin as Universal Dystrophic Markers","volume":"20","author":"Holland","year":"2015","journal-title":"Molecules"},{"key":"ref_283","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s10974-017-9478-4","article-title":"Proteomic profiling of the dystrophin complex and membrane fraction from dystrophic mdx muscle reveals decreases in the cytolinker desmoglein and increases in the extracellular matrix stabilizers biglycan and fibronectin","volume":"38","author":"Murphy","year":"2017","journal-title":"J. Muscle Res. Cell Motil."},{"key":"ref_284","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1002\/pmic.201400471","article-title":"Label-free mass spectrometric analysis of the mdx-4cv diaphragm identifies the matricellular protein periostin as a potential factor involved in dystrophinopathy-related fibrosis","volume":"15","author":"Holland","year":"2015","journal-title":"Proteomics"},{"key":"ref_285","doi-asserted-by":"crossref","unstructured":"Dalton, C.J., and Lemmon, C.A. (2021). Fibronectin: Molecular Structure, Fibrillar Structure and Mechanochemical Signaling. Cells, 10.","DOI":"10.20944\/preprints202108.0010.v1"},{"key":"ref_286","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/prca.201300072","article-title":"Fibronectin is a serum biomarker for Duchenne muscular dystrophy","volume":"8","author":"Hiller","year":"2014","journal-title":"Proteom. Clin. Appl."},{"key":"ref_287","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3892\/ijmm.2012.1006","article-title":"Proteomics reveals drastic increase of extracellular matrix proteins collagen and dermatopontin in the aged mdx diaphragm model of Duchenne muscular dystrophy","volume":"30","author":"Carberry","year":"2012","journal-title":"Int. J. Mol. Med."},{"key":"ref_288","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/03008200600846564","article-title":"Dermatopontin, a novel player in the biology of the extracellular matrix","volume":"47","author":"Okamoto","year":"2006","journal-title":"Connect. Tissue Res."},{"key":"ref_289","doi-asserted-by":"crossref","first-page":"14861","DOI":"10.1074\/jbc.M110.179762","article-title":"Dermatopontin interacts with fibronectin, promotes fibronectin fibril formation, and enhances cell adhesion","volume":"286","author":"Kato","year":"2011","journal-title":"J. Biol. Chem."},{"key":"ref_290","doi-asserted-by":"crossref","first-page":"16385","DOI":"10.1038\/s41598-020-73315-6","article-title":"Cellular senescence-mediated exacerbation of Duchenne muscular dystrophy","volume":"10","author":"Sugihara","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_291","doi-asserted-by":"crossref","unstructured":"Signorelli, M., Tsonaka, R., Aartsma-Rus, A., and Spitali, P. (2023). Multiomic characterization of disease progression in mice lacking dystrophin. PLoS ONE, 18.","DOI":"10.1371\/journal.pone.0283869"},{"key":"ref_292","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/jcsm.12527","article-title":"Comparative proteomic analyses of Duchenne muscular dystrophy and Becker muscular dystrophy muscles: Changes contributing to preserve muscle function in Becker muscular dystrophy patients","volume":"11","author":"Capitanio","year":"2020","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_293","doi-asserted-by":"crossref","unstructured":"Capitanio, D., Moriggi, M., Barbacini, P., Torretta, E., Moroni, I., Blasevich, F., Morandi, L., Mora, M., and Gelfi, C. (2020). Molecular fingerprint of BMD patients lacking a portion in the rod domain of dystrophin. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23052624"},{"key":"ref_294","doi-asserted-by":"crossref","first-page":"4610","DOI":"10.1002\/pmic.200600082","article-title":"Proteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP","volume":"6","author":"Doran","year":"2006","journal-title":"Proteomics"},{"key":"ref_295","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1021\/pr2001385","article-title":"Quantitative proteomic analysis of dystrophic dog muscle","volume":"10","author":"Guevel","year":"2011","journal-title":"J. Proteome Res."},{"key":"ref_296","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1074\/mcp.M112.023127","article-title":"Identification of disease specific pathways using in vivo SILAC proteomics in dystrophin deficient mdx mouse","volume":"12","author":"Rayavarapu","year":"2013","journal-title":"Mol. Cell. Proteom."},{"key":"ref_297","doi-asserted-by":"crossref","first-page":"33362","DOI":"10.1038\/srep33362","article-title":"Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy","volume":"6","author":"Kemter","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_298","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1074\/mcp.RA120.002345","article-title":"Mutation-independent proteomic signatures of pathological progression in murine models of Duchenne muscular dystrophy","volume":"19","author":"Johansson","year":"2020","journal-title":"Mol. Cell. Proteom."},{"key":"ref_299","doi-asserted-by":"crossref","first-page":"680","DOI":"10.2174\/13892037113146660083","article-title":"Proteomics of the dystrophin-glycoprotein complex and dystrophinopathy","volume":"14","author":"Holland","year":"2013","journal-title":"Curr. Protein Pept. Sci."},{"key":"ref_300","doi-asserted-by":"crossref","first-page":"1700071","DOI":"10.1002\/prca.201700071","article-title":"Mass spectrometry-based protein analysis to unravel the tissue pathophysiology in Duchenne muscular dystrophy","volume":"12","author":"Carr","year":"2018","journal-title":"Proteom. Clin. Appl."},{"key":"ref_301","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1080\/14789450.2020.1773806","article-title":"Duchenne Muscular Dystrophy: Recent advances in protein biomarkers and the clinical application","volume":"17","year":"2020","journal-title":"Expert Rev. Proteom."},{"key":"ref_302","doi-asserted-by":"crossref","unstructured":"Gawlik, K.I. (2018). At the Crossroads of Clinical and Preclinical Research for Muscular Dystrophy\u2014Are We Closer to Effective Treatment for Patients?. Int. J. Mol. Sci., 19.","DOI":"10.3390\/ijms19051490"},{"key":"ref_303","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1080\/14737159.2019.1648214","article-title":"Emerging proteomic biomarkers of X-linked muscular dystrophy","volume":"19","author":"Dowling","year":"2019","journal-title":"Expert Rev. Mol. Diagn."},{"key":"ref_304","doi-asserted-by":"crossref","first-page":"dmm043638","DOI":"10.1242\/dmm.043638","article-title":"Biomarkers for Duchenne muscular dystrophy: Myonecrosis, inflammation and oxidative stress","volume":"13","author":"Grounds","year":"2020","journal-title":"Dis. Model Mech."},{"key":"ref_305","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/jcb.21224","article-title":"Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues","volume":"101","author":"Norris","year":"2007","journal-title":"J. Cell. Biochem."},{"key":"ref_306","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.gene.2014.10.014","article-title":"Periostin is temporally expressed as an extracellular matrix component in skeletal muscle regeneration and differentiation","volume":"553","author":"Ozdemir","year":"2014","journal-title":"Gene"},{"key":"ref_307","doi-asserted-by":"crossref","unstructured":"Ito, N., Miyagoe-Suzuki, Y., Takeda, S., and Kudo, A. (2021). Periostin Is Required for the Maintenance of Muscle Fibers during Muscle Regeneration. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22073627"},{"key":"ref_308","doi-asserted-by":"crossref","first-page":"10978","DOI":"10.1073\/pnas.1204708109","article-title":"Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-\u03b2 pathway","volume":"109","author":"Lorts","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_309","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1083\/jcb.201512022","article-title":"An actin-dependent annexin complex mediates plasma membrane repair in muscle","volume":"213","author":"Demonbreun","year":"2016","journal-title":"J. Cell Biol."},{"key":"ref_310","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1093\/hmg\/ddx065","article-title":"Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle","volume":"26","author":"Defour","year":"2017","journal-title":"Hum. Mol. Genet."},{"key":"ref_311","doi-asserted-by":"crossref","unstructured":"Bittel, D.C., Chandra, G., Tirunagri, L.M.S., Deora, A.B., Medikayala, S., Scheffer, L., Defour, A., and Jaiswal, J.K. (2020). Annexin A2 Mediates Dysferlin Accumulation and Muscle Cell Membrane Repair. Cells, 9.","DOI":"10.3390\/cells9091919"},{"key":"ref_312","doi-asserted-by":"crossref","first-page":"50466","DOI":"10.1074\/jbc.M307247200","article-title":"Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing","volume":"278","author":"Lennon","year":"2003","journal-title":"J. Biol. Chem."},{"key":"ref_313","doi-asserted-by":"crossref","unstructured":"Croissant, C., Carmeille, R., Br\u00e9vart, C., and Bouter, A. (2021). Annexins and Membrane Repair Dysfunctions in Muscular Dystrophies. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22105276"},{"key":"ref_314","doi-asserted-by":"crossref","unstructured":"Croissant, C., Gounou, C., Bouvet, F., Tan, S., and Bouter, A. (2022). Trafficking of Annexins during Membrane Repair in Human Skeletal Muscle Cells. Membranes, 12.","DOI":"10.3390\/membranes12020153"},{"key":"ref_315","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/nrm3902","article-title":"Extracellular matrix assembly: A multiscale deconstruction","volume":"15","author":"Mouw","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"ref_316","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3389\/fphys.2020.00253","article-title":"Skeletal Muscle Extracellular Matrix\u2014What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review","volume":"11","author":"Csapo","year":"2020","journal-title":"Front. Physiol."},{"key":"ref_317","doi-asserted-by":"crossref","first-page":"C763","DOI":"10.1152\/ajpcell.00200.2022","article-title":"A glitch in the matrix: The pivotal role for extracellular matrix remodeling during muscle hypertrophy","volume":"323","author":"Brightwell","year":"2022","journal-title":"Am. J. Physiol.-Cell Physiol."}],"container-title":["Biomolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2218-273X\/13\/7\/1108\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:11:26Z","timestamp":1760127086000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2218-273X\/13\/7\/1108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,12]]},"references-count":317,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,7]]}},"alternative-id":["biom13071108"],"URL":"https:\/\/doi.org\/10.3390\/biom13071108","relation":{},"ISSN":["2218-273X"],"issn-type":[{"value":"2218-273X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,12]]}}}