{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:33:45Z","timestamp":1787027625582,"version":"build-2736575974"},"reference-count":81,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T00:00:00Z","timestamp":1702339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research Foundation","award":["SRUG2203291031"],"award-info":[{"award-number":["SRUG2203291031"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomolecules"],"abstract":"<jats:p>Cordyline species have a long history in traditional medicine as a basis of treatment for various ailments such as a bloody cough, dysentery, and a high fever. There are about 26 accepted species names in this genus distributed worldwide, including C. fruticosa, C. autralis, C. stricta, C. cannifolia, and C. dracaenosides. This work presents a comprehensive review of the traditional uses of plants of the genus Cordylie and their chemical constituents and biological activities. A bibliographic search was conducted to identify available information on ethnobotany, ethnopharmacology, chemical composition, and biological activities. A total of 98 isolated compounds potentially responsible for most of the traditional medicinal applications have been reported from eight species of Cordyline and are characterised as flavonoid, spirostane, furostane, and cholestane glycosides. Some of these pure compounds, as well as extracts from some species of Cordyline, have exhibited noteworthy anti-oxidant, antiproliferative, antimicrobial, and hypolipidemic activities. Although many of these species have not yet been investigated phytochemically or pharmacologically, they remain a potential source of new bioactive compounds.<\/jats:p>","DOI":"10.3390\/biom13121783","type":"journal-article","created":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T09:15:33Z","timestamp":1702372533000},"page":"1783","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Ethnobotany, Phytochemistry, and Biological Activities of the Genus Cordyline"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6346-086X","authenticated-orcid":false,"given":"Romuald","family":"Tematio Fouedjou","sequence":"first","affiliation":[{"name":"Research Unit of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0854-5171","authenticated-orcid":false,"given":"Bienvenu","family":"Tsakem","sequence":"additional","affiliation":[{"name":"Research Unit of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Siwe-Noundou","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, P.O. Box 218, Pretoria 0208, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5090-1462","authenticated-orcid":false,"given":"Hervet P.","family":"Dongmo Fogang","sequence":"additional","affiliation":[{"name":"Department of Physiological Sciences and Biochemistry, Faculty of Medicine and Biomedical, Sciences, University of Garoua, Garoua P.O. Box 317, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aphalaine","family":"Tiombou Donkia","sequence":"additional","affiliation":[{"name":"Research Unit of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beaudelaire","family":"Kemvoufo Ponou","sequence":"additional","affiliation":[{"name":"Research Unit of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7289-3408","authenticated-orcid":false,"given":"Madan","family":"Poka","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, P.O. Box 218, Pretoria 0208, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick H.","family":"Demana","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, P.O. Box 218, Pretoria 0208, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2051-9091","authenticated-orcid":false,"given":"R\u00e9my B.","family":"Teponno","sequence":"additional","affiliation":[{"name":"Research Unit of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9on","family":"Azefack Tapondjou","sequence":"additional","affiliation":[{"name":"Research Unit of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,12]]},"reference":[{"key":"ref_1","unstructured":"Katzung, B.G., Masters, S.B., and Trevor, A.J. (1996). 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