{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:12:36Z","timestamp":1760145156098,"version":"build-2065373602"},"reference-count":126,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T00:00:00Z","timestamp":1719705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomolecules"],"abstract":"<jats:p>With the rise in longevity within the population, medicine continues to encounter fresh hurdles necessitating prompt actions, among which are those associated with hip joint aging. Age-related arthropathies encompass damage to bones\u2019 articulating extremities and their supporting structures, such as articular cartilage, and alterations in the quantity and quality of synovial fluid. This study aims to summarize the biomolecular methods of hip joint evaluation focused on its vascularization, using data correlated with biomolecular research on other joints and tissues, in order to reach an objective opinion of the study prospects in this field. Following a retrospective study on most modern biomolecular research methods on the synovium, the capsule, and the articular cartilage of the hip joint, we have hereby concretized certain future research directions in this field that will improve the qualitative and morphofunctional management of the hip joint at an advanced age, even within population categories at risk of developing various degenerative joint pathologies.<\/jats:p>","DOI":"10.3390\/biom14070784","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T12:58:42Z","timestamp":1719925122000},"page":"784","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Advances in Molecular Research on Hip Joint Impingement\u2014A Vascular Perspective"],"prefix":"10.3390","volume":"14","author":[{"given":"Riana Maria","family":"Huzum","sequence":"first","affiliation":[{"name":"Department of Radiology, Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 400347 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marius Valeriu","family":"H\u00eenganu","sequence":"additional","affiliation":[{"name":"Department of Morpho-Functional Sciences I, Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 400347 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bogdan","family":"Huzum","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology, Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 400347 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9856-6496","authenticated-orcid":false,"given":"Delia","family":"H\u00eenganu","sequence":"additional","affiliation":[{"name":"Department of Morpho-Functional Sciences I, Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 400347 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/s13075-022-02859-x","article-title":"Senescence in osteoarthritis: From mechanism to potential treatment","volume":"24","author":"Liu","year":"2022","journal-title":"Arthritis Res. Ther."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1177\/0022034520906793","article-title":"Extracellular Vesicles of Stem Cells to Prevent BRONJ","volume":"99","author":"Watanabe","year":"2020","journal-title":"J. Dent. 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