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This article provides a concise overview of nanotechnology for cancer or cancer nanomedicine and its applications. In light of prevalent issues, such as inadequate precision in targeting initial chemotherapy drugs, susceptibility of nucleic acid drugs to degradation, gene delivery, and the occurrence of common immune-related adverse events during immunotherapy, we explore the potential integration of nanomedicine with these treatment approaches and illustrative examples and highlight the benefits that arise from the utilization of nanomedicine.<\/jats:p>","DOI":"10.3390\/biom15060802","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T12:27:09Z","timestamp":1748867229000},"page":"802","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Biological Nanocarriers in Cancer Therapy: Cutting Edge Innovations in Precision Drug Delivery"],"prefix":"10.3390","volume":"15","author":[{"given":"Ramesh","family":"Ganpisetti","sequence":"first","affiliation":[{"name":"Terasaki Institute of Biomedical Sciences, 21100 Erwin St, Woodland Hills, Los Angeles, CA 91367-3712, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7106-6871","authenticated-orcid":false,"given":"Sanjay","family":"Giridharan","sequence":"additional","affiliation":[{"name":"Arizona State University, 1151 S. 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