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Primary allergic respiratory and skin diseases were taken into consideration, and possible biomarkers of oxidative stress related to sex differences in the onset and development of atopic diseases were analyzed. Understanding how these variables interact with each other, and evaluating the possible common targets, lays the foundation for the development of tailored therapies with an eye to precision medicine.<\/jats:p>","DOI":"10.3390\/biom15101461","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T12:17:02Z","timestamp":1760617022000},"page":"1461","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sex Differences in Oxidative Stress Concerning Allergic Diseases"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-8055-5892","authenticated-orcid":false,"given":"Mattia","family":"Cristallo","sequence":"first","affiliation":[{"name":"Department of Precision and Regenerative Medicine and Ionian Area, Regional Reference Center for Allergic and Immunological Diseases, University of Bari Aldo Moro, 70124 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5062-3076","authenticated-orcid":false,"given":"Fabiana","family":"Furci","sequence":"additional","affiliation":[{"name":"Provincial Healthcare Unit, Section of Allergy, 89900 Vibo Valentia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5436-1501","authenticated-orcid":false,"given":"Marco","family":"Casciaro","sequence":"additional","affiliation":[{"name":"Unit and School of Allergy and Clinical Immunology, Department of Medical Sciences,  University Hospital of Messina, Via Consolare Valeria 1, 98125 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastiano","family":"Gangemi","sequence":"additional","affiliation":[{"name":"Operative Unit and School of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria 1, 98125 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eustachio","family":"Nettis","sequence":"additional","affiliation":[{"name":"Department of Precision and Regenerative Medicine and Ionian Area, Regional Reference Center for Allergic and Immunological Diseases, University of Bari Aldo Moro, 70124 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12940-025-01175-6","article-title":"Sex Differences in the Impact of Extreme Heat on Cardiovascular Disease Outcomes: A Systematic Review and Meta-Analysis","volume":"24","author":"Zhou","year":"2025","journal-title":"Environ. 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