{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:28:13Z","timestamp":1780878493391,"version":"3.54.1"},"reference-count":60,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomimetics"],"abstract":"<jats:p>Background: Tooth extraction is often accompanied by bone tissue loss. This systematic review aims to compare osteoplastic materials for socket preservation. Methods: This systematic review was carried out with the PRISMA statement. To identify relevant studies, a thorough literature search was executed in several databases, such as Medline, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials. The inclusion criteria were restricted to randomized controlled trials, and their methodological quality was evaluated with the Cochrane Risk of Bias tool (ROB 2). Results: Based on the predefined inclusion and exclusion criteria, nine randomized clinical trials published before 2024 were selected for analysis, all of them investigating the application of osteoplastic materials. Six studies performed xenogenic bone augmentation; one of them compared alloplastic and xenogenic materials; two studies described synthetic osteoplastic materials; and one described autogenic bone material. Conclusion: Socket augmentation with osteoplastic materials demonstrates effectiveness in preserving alveolar ridge dimensions and creating favorable conditions for further implant placement, though differences in clinical performance highlight the need for careful material selection.<\/jats:p>","DOI":"10.3390\/biomimetics10110722","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T03:44:39Z","timestamp":1761795879000},"page":"722","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparative Analysis of the Use of Osteoplastic Materials in Socket Augmentation: A Systematic Review"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6376-7802","authenticated-orcid":false,"given":"Diana","family":"Sologova","sequence":"first","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9699-8555","authenticated-orcid":false,"given":"Aida","family":"Kazaryan","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0585-4518","authenticated-orcid":false,"given":"Ilana","family":"Gor","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8526-7147","authenticated-orcid":false,"given":"Susanna","family":"Sologova","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, A. P. Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University (Sechenov University), avenue Vernadsky 96\/1, 119571 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2615-7167","authenticated-orcid":false,"given":"Elena","family":"Smolyarchuk","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, A. P. Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University (Sechenov University), avenue Vernadsky 96\/1, 119571 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4290-4396","authenticated-orcid":false,"given":"Ekaterina","family":"Grigorevskikh","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, A. P. Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University (Sechenov University), avenue Vernadsky 96\/1, 119571 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6298-4186","authenticated-orcid":false,"given":"George","family":"Anikin","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology and Propaedeutics of Internal Diseases, Sechenov University, B.Pirogovskaya 6\/1, 119435 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7357-2745","authenticated-orcid":false,"given":"Aida","family":"Mirzoeva","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4970-2671","authenticated-orcid":false,"given":"Khadi","family":"Albakova","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4337-4531","authenticated-orcid":false,"given":"Ekaterina","family":"Glazunova","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2071-4487","authenticated-orcid":false,"given":"Marina","family":"Skachkova","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3686-2385","authenticated-orcid":false,"given":"Pavel","family":"Petruk","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Department, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8-2 Trubetskaya Str., 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1546-5129","authenticated-orcid":false,"given":"Evgeny","family":"Presnyakov","sequence":"additional","affiliation":[{"name":"Russian Scientific Center of Surgery named after Academician B.V. Petrovsky, Scientific Research Institute of Human Morphology, Academician A.P. Avtsyna, 117418 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1287-264X","authenticated-orcid":false,"given":"Nasirzade","family":"Saba","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4388-8911","authenticated-orcid":false,"given":"Ekaterina","family":"Diachkova","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery of Borovskiy Institute of Dentistry, Sechenov University, Mojaiskii val 11, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Madi, M., Almindil, I., Alrassasi, M., Alramadan, D., Zakaria, O., and Alagl, A.S. (2023). Cone-Beam Computed Tomography and Histological Findings for Socket Preservation Techniques Using Different Grafting Materials: A Systematic Review. J. Funct. Biomater., 14.","DOI":"10.3390\/jfb14050282"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.5037\/jomr.2019.10102","article-title":"Alveolar Ridge Preservation after Tooth Extraction Using Different Bone Graft Materials and Autologous Platelet Concentrates: A Systematic Review","volume":"10","author":"Stumbras","year":"2019","journal-title":"J. Oral Maxillofac. Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.oooo.2024.07.003","article-title":"A Systematic Review and Meta-Analysis on the Use of Regenerative Graft Materials for Socket Preservation in Randomized Clinical Trials","volume":"138","author":"Alavi","year":"2024","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"de Carvalho Formiga, M., Dayube, U.R.C., Chiapetti, C.K., de Rossi Figueiredo, D., and Shibli, J.A. (2019). Socket Preservation Using a (Dense) PTFE Barrier with or without Xenograft Material: A Randomized Clinical Trial. Materials, 12.","DOI":"10.3390\/ma12182902"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"195S","DOI":"10.1177\/0022034513506713","article-title":"Ridge Alterations Post-Extraction in the Esthetic Zone: A 3D Analysis with CBCT","volume":"92","author":"Chappuis","year":"2013","journal-title":"J. Dent. Res."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Passarelli, P.C., Pagnoni, S., Piccirillo, G.B., Desantis, V., Benegiamo, M., Liguori, A., Papa, R., Papi, P., Pompa, G., and D\u2019Addona, A. (2020). Reasons for Tooth Extractions and Related Risk Factors in Adult Patients: A Cohort Study. Int. J. Environ. Res. Public Health, 17.","DOI":"10.3390\/ijerph17072575"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1600-0501.2011.02370.x","article-title":"Evidence-Based Knowledge on the Biology and Treatment of Extraction Sockets","volume":"23","author":"Simion","year":"2012","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"194","DOI":"10.5051\/jpis.2017.47.4.194","article-title":"Alveolar Socket Preservation with Demineralised Bovine Bone Mineral and a Collagen Matrix","volume":"47","author":"Maiorana","year":"2017","journal-title":"J. Periodontal Implant. Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.5037\/jomr.2019.10303","article-title":"Morphological Classification of Extraction Sockets and Clinical Decision Tree for Socket Preservation\/Augmentation after Tooth Extraction: A Systematic Review","volume":"10","author":"Juodzbalys","year":"2019","journal-title":"J. Oral Maxillofac. Res."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1563\/1548-1336(2001)027<0187:ESRFAR>2.3.CO;2","article-title":"Extraction Site Reconstruction for Alveolar Ridge Preservation. Part 1: Rationale and Materials Selection","volume":"27","author":"Bartee","year":"2001","journal-title":"J. Oral Implantol."},{"key":"ref_11","first-page":"CD010176","article-title":"Interventions for Replacing Missing Teeth: Alveolar Ridge Preservation Techniques for Dental Implant Site Development","volume":"4","author":"Atieh","year":"2021","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1034\/j.1600-051X.2003.00366.x","article-title":"Dynamics of Bone Tissue Formation in Tooth Extraction Sites. An Experimental Study in Dogs","volume":"30","author":"Cardaropoli","year":"2003","journal-title":"J. Clin. Periodontol."},{"key":"ref_13","first-page":"260","article-title":"Ridge Preservation Techniques for Implant Therapy","volume":"24","author":"Darby","year":"2009","journal-title":"Int. J. Oral Maxillofac. Implant."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"S1007","DOI":"10.4103\/jpbs.jpbs_1003_23","article-title":"Biphasic Calcium Phosphate in the Extraction Socket Preservation: A Systematic Review","volume":"16","author":"Mohanasatheesh","year":"2024","journal-title":"J. Pharm. Bioallied Sci."},{"key":"ref_15","first-page":"54","article-title":"Biodegradable Materials for Bone Defect Repair","volume":"7","author":"Wei","year":"2020","journal-title":"Mil. Med. Res."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Tang, G., Liu, Z., Liu, Y., Yu, J., Wang, X., Tan, Z., and Ye, X. (2021). Recent Trends in the Development of Bone Regenerative Biomaterials. Front. Cell Dev. Biol., 9.","DOI":"10.3389\/fcell.2021.665813"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s40729-023-00491-1","article-title":"Radiographic and Histological Evaluation of Bone Formation Induced by rhBMP-2-Incorporated Biomimetic Calcium Phosphate Material in Clinical Alveolar Sockets Preservation","volume":"9","author":"Sun","year":"2023","journal-title":"Int. J. Implant. Dent."},{"key":"ref_18","first-page":"465","article-title":"Utilization of D-PTFE Barriers for Post-Extraction Bone Regeneration in Preparation for Dental Implants","volume":"36","author":"Greenstein","year":"2015","journal-title":"Compend. Contin. Educ. Dent."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/clr.12170","article-title":"Ridge Preservation with the Use of Deproteinized Bovine Bone Mineral","volume":"25","author":"Lindhe","year":"2014","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_20","first-page":"70","article-title":"Alveolar Ridge Sockets Preservation with Bone Grafting\u2014Review","volume":"54","author":"Allegrini","year":"2008","journal-title":"Ann. Acad. Med. Stetin."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jobcr.2021.01.016","article-title":"Advanced Platelet-Rich Fibrin plus and Osseous Bone Graft for Socket Preservation and Ridge Augmentation\u2014A Randomized Control Clinical Trial","volume":"11","author":"Yewale","year":"2021","journal-title":"J. Oral Biol. Craniofac. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"419","DOI":"10.11607\/prd.5590","article-title":"Clinical Classification of Healing Complications and Management in Guided Bone Regeneration Procedures with a Nonresorbable D-PTFE Membrane","volume":"42","author":"Vroom","year":"2022","journal-title":"Int. J. Periodontics Restor. Dent."},{"key":"ref_23","first-page":"157","article-title":"Immediate implantation. Preservation of bone volume and osseous regeneration","volume":"10","author":"Werbitt","year":"1991","journal-title":"J. Parodontol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1080\/00016357.2018.1508743","article-title":"Validity of a Regenerative Procedure for a Minor Bone Defect with Immediate Implant Placement: A Systematic Review and Meta-Analysis","volume":"77","author":"Lee","year":"2019","journal-title":"Acta Odontol. Scand."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/jcpe.13058","article-title":"Bone Grafts: Which Is the Ideal Biomaterial?","volume":"46","author":"Haugen","year":"2019","journal-title":"J. Clin. Periodontol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"309","DOI":"10.25122\/jml-2021-0308","article-title":"The Need for Socket Preservation: A Systematic Review","volume":"15","author":"Alenazi","year":"2022","journal-title":"J. Med. Life"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Page, M.J., McKenzie, J.E., Bossuyt, P.M., Boutron, I., Hoffmann, T.C., Mulrow, C.D., Shamseer, L., Tetzlaff, J.M., Akl, E.A., and Brennan, S.E. (2021). The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews. PLOS Med., 18.","DOI":"10.1371\/journal.pmed.1003583"},{"key":"ref_28","unstructured":"(2020). PRISMA 2020 Check List, PRISMA."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"e588","DOI":"10.1093\/pubmed\/fdac036","article-title":"Strengthening Systematic Reviews in Public Health: Guidance in the Cochrane Handbook for Systematic Reviews of Interventions, 2nd Edition","volume":"44","author":"Cumpston","year":"2022","journal-title":"J. Public Health"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1111\/clr.12237","article-title":"A Randomized Controlled Clinical Trial to Evaluate a New Xenograft for Alveolar Socket Preservation","volume":"25","author":"Resende","year":"2014","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_31","first-page":"39","article-title":"Postextraction Socket Preservation Using Epithelial Connective Tissue Graft vs Porcine Collagen Matrix. 1-Year Results of a Randomised Controlled Trial","volume":"8","author":"Meloni","year":"2015","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1111\/cid.12516","article-title":"Randomized Clinical Trial for the Biological Evaluation of Two Nanostructured Biphasic Calcium Phosphate Biomaterials as a Bone Substitute","volume":"19","author":"Uzeda","year":"2017","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_33","first-page":"e5","article-title":"Extraction Socket Preservation Using Porcine-Derived Collagen Membrane Alone or Associated with Porcine-Derived Bone. Clinical Results of Randomized Controlled Study","volume":"8","author":"Guarnieri","year":"2017","journal-title":"J. Oral Maxillofac. Res."},{"key":"ref_34","first-page":"120","article-title":"Effortless Effort in Bone Regeneration: A Review","volume":"6","author":"Nazirkar","year":"2014","journal-title":"J. Int. Oral Health"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"92","DOI":"10.2174\/1874210600903010092","article-title":"Clinical and Histological Comparison of Extraction Socket Healing Following the Use of Autologous Platelet-Rich Fibrin Matrix (PRFM) to Ridge Preservation Procedures Employing Demineralized Freeze Dried Bone Allograft Material and Membrane","volume":"3","author":"Simon","year":"2009","journal-title":"Open Dent. J."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/j.1600-0501.2008.01525.x","article-title":"Effect of Platelet-Rich Plasma on Bone Regeneration in Dentistry: A Systematic Review","volume":"19","author":"Plachokova","year":"2008","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1902\/jop.2011.110237","article-title":"Extraction Socket Preservation Graft before Implant Placement with Calcium Sulfate Hemihydrate and Platelet-Rich Plasma: A Clinical and Histomorphometric Study in Humans","volume":"83","author":"Kutkut","year":"2012","journal-title":"J. Periodontol."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Yao, C., Pripatnanont, P., Zhang, J., and Suttapreyasri, S. (2024). Performance of a Multiphase Bioactive Socket Plug with a Barrier Function for Alveolar Ridge Preservation. Biomed. Mater., 19.","DOI":"10.1088\/1748-605X\/ad5ba7"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"e08796","DOI":"10.1016\/j.heliyon.2022.e08796","article-title":"Scaffolds of Bioactive Glass (Bioglass\u00ae) Combined with Recombinant Human Bone Morphogenetic Protein -9 (rhBMP-9) for Tooth Extraction Site Preservation","volume":"8","author":"Shi","year":"2022","journal-title":"Heliyon"},{"key":"ref_40","first-page":"1199","article-title":"Immediate Loading of Maxillary Prostheses Using Flapless Surgery, Implant Placement in Predetermined Positions, and Prefabricated Provisional Restorations. Part 2: A Retrospective 10-Year Clinical Study","volume":"27","author":"Rocci","year":"2012","journal-title":"Int. J. Oral Maxillofac. Implant."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"245","DOI":"10.5005\/jp-journals-10024-3247","article-title":"Techniques for Extraction Socket Regeneration for Alveolar Ridge Preservation","volume":"23","author":"Jafer","year":"2022","journal-title":"J. Contemp. Dent. Pract."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1046\/j.0905-7161.2003.00952.x","article-title":"Efficacy of Bovine Bone Mineral for Alveolar Augmentation: A Human Histologic Study","volume":"14","author":"Norton","year":"2003","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"435","DOI":"10.5125\/jkaoms.2020.46.6.435","article-title":"Extraction Socket Preservation","volume":"46","author":"Kim","year":"2020","journal-title":"J. Korean Assoc. Oral Maxillofac. Surg."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1600-0501.2007.01407.x","article-title":"Ridge Augmentation by Applying Bioresorbable Membranes and Deproteinized Bovine Bone Mineral: A Report of Twelve Consecutive Cases","volume":"19","author":"Jung","year":"2008","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jormas.2020.10.009","article-title":"Clinical Performance of Alveolar Ridge Augmentation with Xenogeneic Bone Block Grafts versus Autogenous Bone Block Grafts. A Systematic Review","volume":"122","author":"Brinkmann","year":"2021","journal-title":"J. Stomatol. Oral Maxillofac. Surg."},{"key":"ref_46","first-page":"S219","article-title":"Augmentation Procedures Using Bone Substitute Materials or Autogenous Bone\u2014A Systematic Review and Meta-Analysis","volume":"7","author":"Schiegnitz","year":"2014","journal-title":"Eur. J. Oral Implantol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"e251","DOI":"10.1111\/cid.12191","article-title":"Fresh Frozen versus Autogenous Iliac Bone for the Rehabilitation of the Extremely Atrophic Maxilla with Onlay Grafts and Endosseous Implants: Preliminary Results of a Prospective Comparative Study","volume":"17","author":"Chiapasco","year":"2015","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1016\/j.joms.2010.12.004","article-title":"Volume Changes of Grafted Autogenous Bone in Sinus Augmentation Procedure","volume":"69","author":"Sbordone","year":"2011","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Fukuba, S., Okada, M., Nohara, K., and Iwata, T. (2021). Alloplastic Bone Substitutes for Periodontal and Bone Regeneration in Dentistry: Current Status and Prospects. Materials, 14.","DOI":"10.3390\/ma14051096"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1111\/clr.13380","article-title":"Comparison of Allogeneic and Autogenous Bone Grafts for Augmentation of Alveolar Ridge Defects-A 12-Month Retrospective Radiographic Evaluation","volume":"29","author":"Kloss","year":"2018","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1016\/j.joms.2015.06.151","article-title":"Bone Augmented With Allograft Onlays for Implant Placement Could Be Comparable With Native Bone","volume":"73","author":"Torres","year":"2015","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.prosdent.2014.12.009","article-title":"Clinical and Histologic Outcomes of Socket Grafting after Flapless Tooth Extraction: A Systematic Review of Randomized Controlled Clinical Trials","volume":"113","author":"Jambhekar","year":"2015","journal-title":"J. Prosthet. Dent."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"236231","DOI":"10.1155\/2012\/236231","article-title":"An Osteoconductive, Osteoinductive, and Osteogenic Tissue-Engineered Product for Trauma and Orthopaedic Surgery: How Far Are We?","volume":"2012","author":"Khan","year":"2012","journal-title":"Stem Cells Int."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.cobme.2019.02.004","article-title":"Key Terminology in Biomaterials and Biocompatibility","volume":"10","author":"Kolahreez","year":"2019","journal-title":"Curr. Opin. Biomed. Eng."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"269","DOI":"10.11607\/prd.4444","article-title":"Socket Preservation Following Extraction of Molars with Severe Periodontitis","volume":"41","author":"Wei","year":"2021","journal-title":"Int. J. Periodontics Restor. Dent."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"64","DOI":"10.2174\/1389201018666161223152607","article-title":"Molecular, Cellular and Pharmaceutical Aspects of Filling Biomaterials During the Management of Extraction Sockets","volume":"18","author":"Alfonsi","year":"2017","journal-title":"Curr. Pharm. Biotechnol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/prd.12518","article-title":"Bone Regeneration in Implant Dentistry: Which Are the Factors Affecting the Clinical Outcome?","volume":"93","author":"Donos","year":"2023","journal-title":"Periodontology 2000"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.jdent.2012.01.010","article-title":"In Vivo Monitoring of the Bone Healing Process around Different Titanium Alloy Implant Surfaces Placed into Fresh Extraction Sockets","volume":"40","author":"Colombo","year":"2012","journal-title":"J. Dent."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Schorn, L., Sine, A., Berr, K., Handschel, J., Depprich, R., K\u00fcbler, N.R., Sproll, C., Rana, M., and Lommen, J. (2022). Influence of Xenogeneic and Alloplastic Carriers for Bone Augmentation on Human Unrestricted Somatic Stem Cells. Materials, 15.","DOI":"10.3390\/ma15144779"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.joms.2022.10.008","article-title":"Comparative Effects of Different Materials on Alveolar Preservation","volume":"81","author":"Rodrigues","year":"2023","journal-title":"J. Oral Maxillofac. 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