{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T12:14:45Z","timestamp":1790079285846,"version":"4.0.1"},"reference-count":52,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomimetics"],"abstract":"<jats:p>This in vitro study evaluated the shear bond strength (SBS) of resin cement to diabetic and non-diabetic dentin following immediate dentin sealing (IDS) or conventional bonding without IDS, under two cementation protocols: immediate cementation (IC) and one-week delayed cementation (DC) after provisionalization. From a biomimetic perspective, IDS represents a tissue-preserving adhesive approach aimed at maintaining a stable resin\u2013dentin interface; however, systemic conditions such as diabetes mellitus may alter the dentin substrate and affect adhesive performance. A total of 120 extracted human molars were divided into diabetic (n = 60) and non-diabetic (n = 60) groups, each further categorized by adhesive strategy (IDS or without IDS) and cementation protocol (IC or DC). IDS was performed using a three-step etch-and-rinse adhesive system, and cementation was completed with a dual-cure resin cement. Differences in SBS were observed between diabetic and non-diabetic dentin, adhesive strategies, and cementation protocols. Across all conditions, IDS-treated specimens exhibited higher bond strength than those without IDS, and DC resulted in lower SBS than IC in both adhesive strategies. In all subgroups, non-diabetic dentin showed greater SBS than diabetic dentin. The highest SBS was recorded in the non-diabetic IDS-IC group, whereas the lowest was observed in the diabetic without IDS\u2013DC group. Under the tested laboratory conditions, IDS-treated groups showed higher SBS than the corresponding groups without IDS, while the immediate cementation protocol resulted in higher SBS than the delayed cementation protocol.<\/jats:p>","DOI":"10.3390\/biomimetics11090671","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:09:35Z","timestamp":1790075375000},"page":"671","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Immediate Dentin Sealing on the Bond Strength of Resin Cement to Diabetic Dentin"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2478-8010","authenticated-orcid":false,"given":"Ay\u015fenur","family":"Altu\u011f Y\u0131ld\u0131r\u0131m","sequence":"first","affiliation":[{"name":"\u00c7ank\u0131r\u0131 Faculty of Dentistry, Karatekin University, Uluyaz\u0131 Campus, \u00c7ank\u0131r\u0131 18100, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"}]},{"given":"Beyza","family":"Arslanda\u015f Din\u00e7t\u00fcrk","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Gazi University, Bi\u015fkek Cd. (8. Cd.) 1. Sk. No: 8, Ankara 06490, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Cemile","family":"Kedici Alp","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Gazi University, Bi\u015fkek Cd. (8. Cd.) 1. Sk. No: 8, Ankara 06490, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e416","DOI":"10.4317\/jced.61328","article-title":"Influence of diabetes Mellitus and Universal Adhesive Application Mode on the bond strength of Composite Resin to Dentine","volume":"16","author":"Attia","year":"2024","journal-title":"J. Clin. Exp. Dent."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/j.joen.2020.07.025","article-title":"Effect of diabetes on tubular density and push-out bond strength of mineral trioxide aggregate to dentin","volume":"46","author":"Saghiri","year":"2020","journal-title":"J. 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