{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T06:36:37Z","timestamp":1788849397890,"version":"build-2803163510"},"reference-count":74,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T00:00:00Z","timestamp":1699056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006595","name":"Romanian Ministry of Education and Research, CNCS-UEFISCDI","doi-asserted-by":"publisher","award":["PN-III-P4-ID-PCE-2020-2591"],"award-info":[{"award-number":["PN-III-P4-ID-PCE-2020-2591"]}],"id":[{"id":"10.13039\/501100006595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006595","name":"Romanian Ministry of Education and Research, CNCS-UEFISCDI","doi-asserted-by":"publisher","award":["220235050"],"award-info":[{"award-number":["220235050"]}],"id":[{"id":"10.13039\/501100006595","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Program for Research of the National Association of Technical Universities\u2014GNAC ARUT 2023","award":["PN-III-P4-ID-PCE-2020-2591"],"award-info":[{"award-number":["PN-III-P4-ID-PCE-2020-2591"]}]},{"name":"National Program for Research of the National Association of Technical Universities\u2014GNAC ARUT 2023","award":["220235050"],"award-info":[{"award-number":["220235050"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomimetics"],"abstract":"<jats:p>Magnesium (Mg) alloys are adequate materials for orthopedic and maxilo-facial implants due to their biocompatibility, good mechanical properties closely related to the hard tissues, and processability. Their main drawbacks are the high-speed corrosion process and hydrogen release. In order to improve corrosion and mechanical properties, the Mg matrix can be strengthened through alloying elements with high temperature-dependent solubility materials. Rare earth elements (RE) contribute to mechanical properties and degradation improvement. Another possibility to reduce the corrosion rate of Mg-based alloys was demonstrated to be the different types of coatings (bioceramics, polymers, and composites) applied on their surface. The present investigation is related to the coating of two Mg-based alloys from the system Mg3Nd (Mg-Nd-Y-Zr-Zn) with polymeric-based composite coatings made from cellulose acetate (CA) combined with two fillers, respectively hydroxyapatite (HAp) and Mg particles. The main functions of the coatings are to reduce the biodegradation rate and to modify the surface properties in order to increase osteointegration. Firstly, the microstructural features of the experimental Mg3Nd alloys were revealed by optical microscopy and scanning electron microscopy (SEM) coupled with energy-dispersive spectroscopy. Apart from the surface morphology revealed by SEM, the roughness and wettability of all experimental samples were evaluated. The corrosion behavior of the uncoated and coated samples of both Mg3Nd alloys was investigated by immersion testing and electrochemical testing using Simulated Body Fluid as the medium. The complex in vitro research performed highlights that the composite coating based on CA with HAp particles exhibited the best protective effect for both Mg3Nd alloys.<\/jats:p>","DOI":"10.3390\/biomimetics8070526","type":"journal-article","created":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T14:51:01Z","timestamp":1699109461000},"page":"526","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys"],"prefix":"10.3390","volume":"8","author":[{"given":"Alexandru","family":"Streza","sequence":"first","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurora","family":"Antoniac","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2535-5698","authenticated-orcid":false,"given":"Veronica Manescu","family":"Manescu (Paltanea)","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"},{"name":"Faculty of Electrical Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2333-0099","authenticated-orcid":false,"given":"Robert","family":"Ciocoiu","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8991-7485","authenticated-orcid":false,"given":"Cosmin-Mihai","family":"Cotrut","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2723-6713","authenticated-orcid":false,"given":"Marian","family":"Miculescu","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6757-5616","authenticated-orcid":false,"given":"Florin","family":"Miculescu","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0112-3494","authenticated-orcid":false,"given":"Iulian","family":"Antoniac","sequence":"additional","affiliation":[{"name":"Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania"},{"name":"Academy of Romanian Scientists, 54 Splaiul Independentei Street, District 5, 050094 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0962-8083","authenticated-orcid":false,"given":"Marco","family":"Fosca","sequence":"additional","affiliation":[{"name":"Istituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100, 00133 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7953-1853","authenticated-orcid":false,"given":"Julietta V.","family":"Rau","sequence":"additional","affiliation":[{"name":"Istituto di Struttura della Materia, Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100, 00133 Rome, Italy"},{"name":"Department of Analytical, Physical and Colloid Chemistry, Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Trubetskaya Street 8, Build. 2, 119048 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horatiu","family":"Dura","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Lucian Blaga University of Sibiu, 2A Lucian Blaga Street, 550169 Sibiu, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jma.2021.05.012","article-title":"The Role and Significance of Magnesium in Modern Day Research-A Review","volume":"10","author":"Prasad","year":"2022","journal-title":"J. Magnes. Alloys"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Antoniac, I., Miculescu, M., M\u0103nescu, V., Stere, A., Quan, P.H., P\u0103lt\u00e2nea, G., Robu, A., and Earar, K. (2022). Magnesium-Based Alloys Used in Orthopedic Surgery. 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