{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:11:10Z","timestamp":1760145070428,"version":"build-2065373602"},"reference-count":45,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T00:00:00Z","timestamp":1718582400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomimetics"],"abstract":"<jats:p>Background: Zeolite can release antimicrobial silver ions in a targeted and controlled manner for an extended time, selectively inhibiting the growth of pathogenic oral bacteria when added to dental materials. The objective of this study was to investigate the effect of the addition of zeolite to silver-reinforced glass ionomer cement on the release of silver ions over time. Methods: Five concentrations of silver\u2013zeolite (0%, 0.5%, 1%, 2%, 4% wt) were incorporated into silver-reinforced GIC in the form of 10 mm \u00d7 2 mm circular disks (n = 5). The disks were incubated in deionized water at 37 \u00b0C and ion release from the samples was measured at 1, 2, 7, and 30 days after immersion by inductively coupled atomic emission spectroscopy. Results: Incorporating silver\u2013zeolite increased silver ion release from silver-reinforced GIC disks compared to the control disks (p &lt; 0.05), while incorporating zeolite alone had no effect. Higher concentrations of added silver\u2013zeolite resulted in increased silver ion release. Sustained silver ion release was observed for up to 30 days. Conclusion: Adding silver\u2013zeolite to silver-reinforced GIC may enhance its extended antibacterial effect in the oral cavity.<\/jats:p>","DOI":"10.3390\/biomimetics9060365","type":"journal-article","created":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T06:29:43Z","timestamp":1718605783000},"page":"365","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Zeolite Incorporation on the Ion Release Properties of Silver-Reinforced Glass Ionomer Cement"],"prefix":"10.3390","volume":"9","author":[{"given":"Jessica","family":"Tan","sequence":"first","affiliation":[{"name":"School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9741-3113","authenticated-orcid":false,"given":"Jessica","family":"Hao","sequence":"additional","affiliation":[{"name":"School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5153-6206","authenticated-orcid":false,"given":"David","family":"Vann","sequence":"additional","affiliation":[{"name":"School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7706-6858","authenticated-orcid":false,"given":"Kre\u0161imir","family":"Paveli\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Juraj Dobrila University of Pula, 52100 Pula, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1213-4957","authenticated-orcid":false,"given":"Fusun","family":"Ozer","sequence":"additional","affiliation":[{"name":"School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Sidhu, S., and Nicholson, J. 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