{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:52:05Z","timestamp":1790236325318,"version":"4.1.0"},"reference-count":40,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T00:00:00Z","timestamp":1586822400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2018R1A2B6009591"],"award-info":[{"award-number":["2018R1A2B6009591"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002641","name":"Konkuk University","doi-asserted-by":"publisher","award":["2018"],"award-info":[{"award-number":["2018"]}],"id":[{"id":"10.13039\/501100002641","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biosensors"],"abstract":"<jats:p>The immunoglobulin E (IgE) level in serum is an important factor in the examination of allergy. Ferrocene (Fc)-modified self-assembled monolayers (SAMs) were placed on an indium tin oxide (ITO) electrode as a sensing layer for the detection of human IgE. The Fc moiety in the SAMs facilitated the electron transfer through the organic SAMs layer and electrocatalytic signal amplification. The electrochemical measurement was accomplished after the sandwich type immobilization of the receptor antibody, target human IgE, and enzyme conjugated secondary antibody. The enzyme product, p-aminophenol, was quantitatively analyzed by redox cycling via Fc. In addition, the electrochemical impedance spectroscopy (EIS) was investigated for the detection of IgE. The limit of detection (LOD), limit of quantification (LOQ), and dynamic range of the electrochemical sensor were 3 IU\/mL, 10 IU\/mL, and from 10 IU\/mL to 100 IU\/mL, respectively.<\/jats:p>","DOI":"10.3390\/bios10040038","type":"journal-article","created":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T04:01:46Z","timestamp":1586923306000},"page":"38","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Electrochemical Immunosensor for Human IgE Using Ferrocene Self-Assembled Monolayers Modified ITO Electrode"],"prefix":"10.3390","volume":"10","author":[{"given":"Myungsang","family":"Park","sequence":"first","affiliation":[{"name":"Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yesol","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Jun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Jun","family":"Oh","sequence":"additional","affiliation":[{"name":"Pioneering Research Center, LG Chem. Ltd., 30 Magokjungang 10-ro, Gangseo-gu, Seoul 07796, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Ki","family":"Ahn","sequence":"additional","affiliation":[{"name":"Pioneering Research Center, LG Chem. Ltd., 30 Magokjungang 10-ro, Gangseo-gu, Seoul 07796, Korea"},{"name":"Human Convergence Technology Group, Korea Institute of Industrial Technology (KITECH), 143 Hanggaul-ro, Sangnok-gu, Ansan 15588, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hun","family":"Park","sequence":"additional","affiliation":[{"name":"Pioneering Research Center, LG Chem. Ltd., 30 Magokjungang 10-ro, Gangseo-gu, Seoul 07796, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2212-4122","authenticated-orcid":false,"given":"Hang-Beum","family":"Shin","sequence":"additional","affiliation":[{"name":"Pioneering Research Center, LG Chem. Ltd., 30 Magokjungang 10-ro, Gangseo-gu, Seoul 07796, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong Jung","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.5858\/2000-124-1382-IE","article-title":"Immunoglobulin E Importance in Parasitic Infections and Hypersensitivity Responses","volume":"124","author":"Winter","year":"2000","journal-title":"Arch. Pathol. Lab. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/ACI.0b013e3283036a90","article-title":"Understanding the mechanisms of anaphylaxis","volume":"8","author":"Peavy","year":"2008","journal-title":"Curr. Opin. Allergy Clin. 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