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quest for effective gas sensors for breath analysis, magnetoelastic resonance-based gas sensors (MEGSs) are remarkable candidates. Thanks to their intrinsic contactless operation, they can be used as non-invasive and portable devices. However, traditional monitoring techniques are bound to slow detection, which hinders their application to fast bio-related reactions. Here we present a method for real-time monitoring of the resonance frequency, with a proof of concept for real-time monitoring of gaseous biomarkers based on resonance frequency. This method was validated with a MEGS based on a Metglass 2826 MB microribbon with a polyvinylpyrrolidone (PVP) nanofiber electrospun functionalization. The device provided a low-noise (RMS = 1.7 Hz), fast (&lt;2 min), and highly reproducible response to humidity (\u0394f = 46\u2013182 Hz for 17\u201395% RH), ammonia (\u0394f = 112 Hz for 40 ppm), and acetone (\u0394f = 44 Hz for 40 ppm). These analytes are highly important in biomedical applications, particularly ammonia and acetone, which are biomarkers related to diseases such as diabetes. Furthermore, the capability of distinguishing between breath and regular air was demonstrated with real breath measurements. The sensor also exhibited strong resistance to benzene, a common gaseous interferent in breath analysis.<\/jats:p>","DOI":"10.3390\/bios12100871","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T20:55:11Z","timestamp":1665694511000},"page":"871","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Real-Time Monitoring of Breath Biomarkers with A Magnetoelastic Contactless Gas Sensor: A Proof of Concept"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9002-8386","authenticated-orcid":false,"given":"Alvaro","family":"Pe\u00f1a","sequence":"first","affiliation":[{"name":"Instituto de Magnetismo Aplicado (IMA), Universidad Complutense de Madrid-Administrador de Infraestructuras Ferroviarias (UCM-ADIF), 28230 Las Rozas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9231-6691","authenticated-orcid":false,"given":"Juan Diego","family":"Aguilera","sequence":"additional","affiliation":[{"name":"Instituto de Magnetismo Aplicado (IMA), Universidad Complutense de Madrid-Administrador de Infraestructuras Ferroviarias (UCM-ADIF), 28230 Las Rozas, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3139-3778","authenticated-orcid":false,"given":"Daniel","family":"Matatagui","sequence":"additional","affiliation":[{"name":"Instituto de Magnetismo Aplicado (IMA), Universidad Complutense de Madrid-Administrador de Infraestructuras Ferroviarias (UCM-ADIF), 28230 Las Rozas, Spain"},{"name":"Departamento de F\u00edsica de Materiales, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain"},{"name":"Grupo de Tecnolog\u00eda de Sensores Avanzados (SENSAVAN), Instituto de Tecnolog\u00edas F\u00edsicas y de la Informaci\u00f3n (ITEFI), Consejo Superior de Investigaciones Cient\u00edficas (CSIC), 28006 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9456-8320","authenticated-orcid":false,"given":"Patricia","family":"de la Presa","sequence":"additional","affiliation":[{"name":"Instituto de Magnetismo Aplicado (IMA), Universidad Complutense de Madrid-Administrador de Infraestructuras Ferroviarias (UCM-ADIF), 28230 Las Rozas, Spain"},{"name":"Departamento de F\u00edsica de Materiales, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2554-3119","authenticated-orcid":false,"given":"Carmen","family":"Horrillo","sequence":"additional","affiliation":[{"name":"Grupo de Tecnolog\u00eda de Sensores Avanzados (SENSAVAN), Instituto de Tecnolog\u00edas F\u00edsicas y de la Informaci\u00f3n (ITEFI), Consejo Superior de Investigaciones Cient\u00edficas (CSIC), 28006 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7307-8859","authenticated-orcid":false,"given":"Antonio","family":"Hernando","sequence":"additional","affiliation":[{"name":"Instituto de Magnetismo Aplicado (IMA), Universidad Complutense de Madrid-Administrador de Infraestructuras Ferroviarias (UCM-ADIF), 28230 Las Rozas, Spain"},{"name":"Donostia International Physics Center, 20018 Donostia, Spain"},{"name":"Instituto Madrile\u00f1o de Estudios Avanzados (IMDEA) Nanociencia, 28049 Madrid, Spain"},{"name":"Departamento de Ingenier\u00eda, Universidad de Nebrija, 28015 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Mar\u00edn","sequence":"additional","affiliation":[{"name":"Instituto de Magnetismo Aplicado (IMA), Universidad Complutense de Madrid-Administrador de Infraestructuras Ferroviarias (UCM-ADIF), 28230 Las Rozas, Spain"},{"name":"Departamento de F\u00edsica de Materiales, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,13]]},"reference":[{"key":"ref_1","unstructured":"Theatkston, F. 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