{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:37:01Z","timestamp":1779291421484,"version":"3.51.4"},"reference-count":33,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biosensors"],"abstract":"<jats:p>Occupational stress is a major challenge in modern societies, related with many health and economic implications. Its automatic detection in an office environment can be a key factor toward effective management, especially in the post-COVID era of changing working norms. The aim of this study is the design, development and validation of a multisensor system embedded in a computer mouse for the detection of office work stress. An experiment is described where photoplethysmography (PPG) and galvanic skin response (GSR) signals of 32 subjects were obtained during the execution of stress-inducing tasks that sought to simulate the stressors present in a computer-based office environment. Kalman and moving average filters were used to process the signals and appropriately formulated algorithms were applied to extract the features of pulse rate and skin conductance. The results found that the stressful periods of the experiment significantly increased the participants\u2019 reported stress levels while negatively affecting their cognitive performance. Statistical analysis showed that, in most cases, there was a highly significant statistical difference in the physiological parameters measured during the different periods of the experiment, without and with the presence of stressors. These results indicate that the proposed device can be part of an unobtrusive system for monitoring and detecting the stress levels of office workers.<\/jats:p>","DOI":"10.3390\/bios13010010","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T03:24:30Z","timestamp":1671679470000},"page":"10","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["A Multisensor System Embedded in a Computer Mouse for Occupational Stress Detection"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3200-284X","authenticated-orcid":false,"given":"Thelma","family":"Androutsou","sequence":"first","affiliation":[{"name":"Biomedical Engineering Laboratory, National Technical University of Athens, 15772 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2533-435X","authenticated-orcid":false,"given":"Spyridon","family":"Angelopoulos","sequence":"additional","affiliation":[{"name":"Laboratory of Electronic Sensors, National Technical University of Athens, 15772 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1895-6417","authenticated-orcid":false,"given":"Evangelos","family":"Hristoforou","sequence":"additional","affiliation":[{"name":"Laboratory of Electronic Sensors, National Technical University of Athens, 15772 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2600-9914","authenticated-orcid":false,"given":"George K.","family":"Matsopoulos","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Laboratory, National Technical University of Athens, 15772 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1205-9918","authenticated-orcid":false,"given":"Dimitrios D.","family":"Koutsouris","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Laboratory, National Technical University of Athens, 15772 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,22]]},"reference":[{"key":"ref_1","unstructured":"(2022, December 21). 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