{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:44:41Z","timestamp":1787496281784,"version":"build-2736575974"},"reference-count":53,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T00:00:00Z","timestamp":1672876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"DSR"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biosensors"],"abstract":"<jats:p>Herein, the detection of aspartic acid by doped Co3O4-ZnO nanorod materials was proposed using differential pulse voltammetry. The nano-composite metal oxide was synthesized by the wet precipitation method in basic media. Aspartic acid is a non-essential amino acid naturally synthesized in the body with lot of health significance, including as a biomarker for several health deficiencies. The synthesized composite Co3O4-ZnO nanorod was well-investigated by using FESEM, XRD, XPS, FTIR, UV\/vis., EIS, and CV. The synthesized composite exhibited a low limit of detection (0.03 \u00b5M, high sensitivity (0.0014 \u00b5A \u00b5M\u22121 cm\u22122) and wide linear range (0.05\u201350 \u00b5M) for aspartic acid. The substrate, the Co3O4-ZnO nanorod, enhanced the electro-catalytic oxidation of aspartic acid as a result of its catalytic and conductivity properties. The developed sensor based on Co3O4-ZnO has a repeatable, reproducible and stable current response for aspartic acid. Additionally, other electroactive compounds did not interfere with the sensor\u2019s current response. The suitability of the developed sensor for real sample analysis was also established. Therefore, this study proposed the potential use of Co3O4-ZnO nanorod material in healthcare management for the maintenance of human well-being.<\/jats:p>","DOI":"10.3390\/bios13010088","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T04:12:56Z","timestamp":1672891976000},"page":"88","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Sensitive and Rapid Detection of Aspartic Acid with Co3O4-ZnO Nanorods Using Differential Pulse Voltammetry"],"prefix":"10.3390","volume":"13","author":[{"given":"Sulaiman Y.","family":"Alfaifi","sequence":"first","affiliation":[{"name":"Chemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waheed Abiodun","family":"Adeosun","sequence":"additional","affiliation":[{"name":"Chemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia"},{"name":"Center of Excellence for Advanced Materials Research (CEAMR), King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7905-3209","authenticated-orcid":false,"given":"Abdullah M.","family":"Asiri","sequence":"additional","affiliation":[{"name":"Chemistry Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia"},{"name":"Center of Excellence for Advanced Materials Research (CEAMR), King Abdulaziz University, P.O. 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