{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T16:31:02Z","timestamp":1782491462841,"version":"3.54.5"},"reference-count":59,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T00:00:00Z","timestamp":1674691200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22276069"],"award-info":[{"award-number":["22276069"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["ZR2021MB047"],"award-info":[{"award-number":["ZR2021MB047"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["22276069"],"award-info":[{"award-number":["22276069"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2021MB047"],"award-info":[{"award-number":["ZR2021MB047"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biosensors"],"abstract":"<jats:p>Hydrogen peroxide (H2O2) and glucose play a key role in many cellular signaling pathways. The efficient and accurate in situ detection of H2O2 released from living cells has attracted extensive research interests. Herein, a new porphyrin-based porous covalent organic framework (TAP-COF) was fabricated via one-step condensation of 1,6,7,12-tetrachloroperylene tetracarboxylic acid dianhydride and 5,10,15,20-tetrakis (4-aminophenyl)porphyrin iron(III). The obtained TAP-COF has high surface areas, abundant surface catalytic active sites, and highly effective electron transport due to its precisely controllable donor\u2013acceptor arrangement and 3D porous structure. Then, the new TAP-COF exhibited excellent peroxidase-like catalytic activity, which could effectively catalyze oxidation of the substrate 3,3\u2032,5,5\u2032-tetramethylbenzidine by H2O2 to produce a typical blue-colored reaction. On this basis, simple, rapid and selective colorimetric methods for in situ H2O2 detection were developed with the detection limit of 2.6 nM in the wide range of 0.01 to 200 \u03bcM. The colorimetric approach also could be used for in situ detection of H2O2 released from living MCF-7 cells. This portable sensor based on a COF nanozyme not only opens a new path for point-of-care testing, but also has potential applications in the field of cell biology and clinical diagnosis.<\/jats:p>","DOI":"10.3390\/bios13020188","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T01:27:58Z","timestamp":1674782878000},"page":"188","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Porphyrin-Based Covalent Organic Frameworks with Donor-Acceptor Structure for Enhanced Peroxidase-like Activity as a Colorimetric Biosensing Platform"],"prefix":"10.3390","volume":"13","author":[{"given":"Qian","family":"Wang","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Lv","sequence":"additional","affiliation":[{"name":"Jinan Agricultural Product Quality and Safety Center, Jinan 250316, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhao","family":"Chi","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujiao","family":"Bai","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqing","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6874-9013","authenticated-orcid":false,"given":"Peihua","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5043-0322","authenticated-orcid":false,"given":"Jinghua","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"17910","DOI":"10.1021\/jacs.1c06673","article-title":"Single Biomolecule Imaging by Electrochemiluminescence","volume":"143","author":"Liu","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"11994","DOI":"10.1021\/acs.analchem.9b02901","article-title":"Fe-N-C Single-Atom Nanozymes for the Intracellular Hydrogen Peroxide Detection","volume":"91","author":"Jiao","year":"2019","journal-title":"Anal. Chem."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.carbpol.2019.02.053","article-title":"Detection of Hydrogen Peroxide (H2O2) Using a Colorimetric Sensor Based on Cellulose Nanowhiskers and Silver Nanoparticles","volume":"212","author":"Teodoro","year":"2019","journal-title":"Carbohydr. Polym"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1007\/s41664-020-00124-1","article-title":"Electrochemiluminescence Sensor for Cancer Cell Detection Based on H2O2-Triggered Stimulus Response System","volume":"4","author":"Chen","year":"2020","journal-title":"J. Anal. Test."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"5278","DOI":"10.1021\/acs.analchem.6b04810","article-title":"A Fluorescent Probe for Hydrogen Peroxide in Vivo Based on the Modulation of Intramolecular Charge Transfer","volume":"89","author":"Chen","year":"2017","journal-title":"Anal. Chem."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"128886","DOI":"10.1016\/j.snb.2020.128886","article-title":"Bovine Serum Albumin Decorated Gold Nanoclusters: A Fluorescence-Based Nanoprobe for Detection of Intracellular Hydrogen Peroxide","volume":"327","author":"Jain","year":"2021","journal-title":"Sens. Actuators B"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"10173","DOI":"10.1002\/anie.201805162","article-title":"Tandem Payne\/Dakin Reaction: A New Strategy for Hydrogen Peroxide Detection and Molecular Imaging","volume":"57","author":"Ye","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"17836","DOI":"10.1021\/ja510421q","article-title":"Mitochondrial Induced and Self-Monitored Intrinsic Apoptosis by Antitumor Theranostic Prodrug: In Vivo Imaging and Precise Cancer Treatment","volume":"136","author":"Kumar","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.snb.2018.05.029","article-title":"\u201cOn\/Off\/On\u201d Hydrogen-Peroxide Sensor with Hemoglobin-Functionalized Carbon Dots","volume":"270","author":"Bhunia","year":"2018","journal-title":"Sens. Actuators B"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"128605","DOI":"10.1016\/j.jhazmat.2022.128605","article-title":"Ultra-Sensitive Detection of Hydrogen Peroxide and Levofloxacin Using a Dual-Functional Fluorescent Probe","volume":"432","author":"Shi","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/cnma.202100125","article-title":"Triphenylphosphonium-Derived Bright Green Fluorescent Carbon Dots for Mitochondrial Targeting and Rapid Selective Detection of Tetracycline","volume":"7","author":"Rajendran","year":"2021","journal-title":"ChemNanoMat"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"9864","DOI":"10.1021\/acs.analchem.7b01939","article-title":"Stainless Steel Electrode for Sensitive Luminol Electrochemiluminescent Detection of H2O2, Glucose, and Glucose Oxidase Activity","volume":"89","author":"Kitte","year":"2017","journal-title":"Anal. Chem."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.snb.2018.02.151","article-title":"FeNPs@Co3O4 Hollow Nanocages Hybrids as Effective Peroxidase Mimics for Glucose Biosensing","volume":"263","author":"Zhao","year":"2018","journal-title":"Sens. Actuators B"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"14081","DOI":"10.1039\/D2NJ02174A","article-title":"Citrate Capped Silver Nanoparticles as an Instantaneous Colorimetric Selective Sensor for Neomycin and Thiamine in Wastewater","volume":"46","author":"UshaVipinachandran","year":"2022","journal-title":"New J. Chem."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.snb.2018.05.108","article-title":"Colorimetric and Ultrasensitive Detection of H2O2 Based on Au\/Co3O4-CeOx Nanocomposites with Enhanced Peroxidase-Like Performance","volume":"271","author":"Liu","year":"2018","journal-title":"Sens. Actuators B"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"10636","DOI":"10.1021\/acs.analchem.2c00804","article-title":"A Dopamine-Enabled Universal Assay for Catalase and Catalase-Like Nanozymes","volume":"94","author":"Lin","year":"2022","journal-title":"Anal. Chem."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"22155","DOI":"10.1039\/C8NR07288D","article-title":"An Ultrathin Iron-Porphyrin Based Nanocapsule with High Peroxidase-Like Activity for Highly Sensitive Glucose Detection","volume":"10","author":"Fan","year":"2018","journal-title":"Nanoscale"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.bios.2015.03.026","article-title":"A Highly Sensitive Electrochemiluminescence Assay for Protein Kinase Based on Double-Quenching of Graphene Quantum Dots by G-quadruplex-Hemin and Gold Nanoparticles","volume":"70","author":"Liu","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"ref_19","first-page":"10870","article-title":"Porphyrin-Based Porous Organic Polymer as Peroxidase Mimics for Sulfide-Ion Colorimetric Sensing","volume":"8","author":"Li","year":"2020","journal-title":"ACS Sustain. Chem. Eng."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.snb.2017.05.069","article-title":"A Facile Strategy to Prepare Porphyrin Functionalized ZnS Nanoparticles and Their Peroxidase-Like Catalytic Activity for Colorimetric Sensor of Hydrogen Peroxide and Glucose","volume":"251","author":"Liu","year":"2017","journal-title":"Sens. Actuators B"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"8989","DOI":"10.1021\/acsami.9b20102","article-title":"Bacterial Detection and Elimination Using a Dual-Functional Porphyrin-Based Porous Organic Polymer with Peroxidase-Like and High Near-Infrared-Light-Enhanced Antibacterial Activity","volume":"12","author":"Li","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1002\/anie.201308896","article-title":"Highly Efficient Electrocatalysts for Oxygen Reduction Based on 2D Covalent Organic Polymers Complexed with Non-Precious Metals","volume":"53","author":"Xiang","year":"2014","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"127559","DOI":"10.1016\/j.cej.2020.127559","article-title":"In Situ Grown COFs on 3D Strutted Graphene Aerogel for Electrochemical Detection of NO Released from Living Cells","volume":"420","author":"Zhu","year":"2021","journal-title":"Chem. Eng. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"110864","DOI":"10.1016\/j.msec.2020.110864","article-title":"Iron-Porphyrin-Based Covalent-Organic Frameworks for Electrochemical Sensing H2O2 and pH","volume":"112","author":"Xie","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"21750","DOI":"10.1021\/acsami.2c04391","article-title":"Construction of Donor-Acceptor Heteroporous Covalent Organic Frameworks as Photoregulated Oxidase-Like Nanozymes for Sensing Signal Amplification","volume":"14","author":"Li","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/s41557-019-0327-5","article-title":"On-Water Surface Synthesis of Crystalline, Few-Layer Two-Dimensional Polymers Assisted by Surfactant Monolayers","volume":"11","author":"Liu","year":"2019","journal-title":"Nat. Chem."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"7104","DOI":"10.1021\/jacs.1c02145","article-title":"Two-Dimensional Covalent Organic Frameworks with Cobalt(II)-Phthalocyanine Sites for Efficient Electrocatalytic Carbon Dioxide Reduction","volume":"143","author":"Han","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"18552","DOI":"10.1039\/c1jm13082j","article-title":"The First Solution-Processable n-Type Phthalocyaninato Copper Semiconductor: Tuning the Semiconducting Nature Via Peripheral Electron-Withdrawing Octyloxycarbonyl Substituents","volume":"21","author":"Ma","year":"2011","journal-title":"J. Mater. Chem."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1021\/acs.chemmater.5b04947","article-title":"Interplaying Intrinsic and Extrinsic Proton Conductivities in Covalent Organic Frameworks","volume":"28","author":"Chandra","year":"2016","journal-title":"Chem. Mater."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"20397","DOI":"10.1021\/acsami.1c00335","article-title":"Porphyrin-Based Covalent Organic Framework Thin Films as Cathodic Materials for \u201cOn\u2013Off\u2013On\u201d Photoelectrochemical Sensing of Lead Ions","volume":"13","author":"Zhao","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.1016\/j.jcis.2021.11.034","article-title":"High-Activity Daisy-Like Zeolitic Imidazolate Framework-67\/Reduced Grapheme Oxide-Based Colorimetric Biosensor for Sensitive Detection of Hydrogen Peroxide","volume":"608","author":"Lu","year":"2022","journal-title":"J. Colloid Interface Sci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"3514","DOI":"10.1021\/acsami.6b15637","article-title":"Porphyrin-Based Porous Organic Frameworks as a Biomimetic Catalyst for Highly Efficient Colorimetric Immunoassay","volume":"9","author":"Deng","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.aca.2013.08.008","article-title":"Co3O4-Reduced Graphene Oxide Nanocomposite as an Effective Peroxidase Mimetic and Its Application in Visual Biosensing of Glucose","volume":"796","author":"Xie","year":"2013","journal-title":"Anal. Chim. Acta"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"4526","DOI":"10.1039\/c3an00560g","article-title":"A Nanosized Metal-Organic Framework of Fe-MIL-88NH2 as a Novel Peroxidase Mimic Used for Colorimetric Detection of Glucose","volume":"138","author":"Liu","year":"2013","journal-title":"Analyst"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"6695","DOI":"10.1039\/c1cc11943e","article-title":"Carbon Nanodots as Peroxidase Mimetics and Their Applications to Glucose Detection","volume":"47","author":"Shi","year":"2011","journal-title":"Chem. Commun."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.trac.2019.06.031","article-title":"Recent Progress In the Development of Small-Molecule Fluorescent Probes for the Detection of Hydrogen Peroxide","volume":"118","author":"Zheng","year":"2019","journal-title":"TrAC Trends Anal. Chem."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"3874","DOI":"10.1021\/acs.analchem.9b05343","article-title":"DNAzyme-Triggered Visual and Ratiometric Electrochemiluminescence Dual-Readout Assay for Pb(II) Based on an Assembled Paper Device","volume":"92","author":"Zhang","year":"2020","journal-title":"Anal. Chem."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"127203","DOI":"10.1016\/j.cej.2020.127203","article-title":"Real-Time Photoelectrochemical Quantification of Hydrogen Peroxide Produced by Living Cells","volume":"407","author":"Hu","year":"2021","journal-title":"Chem. Eng. J."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"3969","DOI":"10.1039\/c2nr12109c","article-title":"Graphene Oxide-Fe3O4 Magnetic Nanocomposites with Peroxidase-Like Activity for Colorimetric Detection of Glucose","volume":"4","author":"Dong","year":"2012","journal-title":"Nanoscale"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Zhu, D., Kong, H., Yang, G., He, P., Luan, X., Guo, L., and Wei, G. (2022). Peptide Nanosheet-Inspired Biomimetic Synthesis of CuS Nanoparticles on Ti3C2 Nanosheets for Electrochemical Biosensing of Hydrogen Peroxide. Biosensors, 13.","DOI":"10.3390\/bios13010014"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1021\/nn901742q","article-title":"Multifunction Oval-Shaped Gold-Nanoparticle-Based Selective Detection of Breast Cancer Cells Using Simple Colorimetric and Highly Sensitive Two-Photon Scattering Assay","volume":"4","author":"Lu","year":"2010","journal-title":"ACS Nano"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jcis.2020.06.001","article-title":"Electronic Coupling Between Molybdenum Disulfide and Gold Nanoparticles to Enhance the Peroxidase Activity for the Colorimetric Immunoassays of Hydrogen Peroxide and Cancer Cells","volume":"578","author":"Sun","year":"2020","journal-title":"J. Colloid Interface Sci."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1039\/C8NR08337A","article-title":"A Multifunctional Mesoporous Silica-Gold Nanocluster Hybrid Platform for Selective Breast Cancer Cell Detection Using a Catalytic Amplification-Based Colorimetric Assay","volume":"11","author":"Li","year":"2019","journal-title":"Nanoscale"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jechem.2020.09.039","article-title":"Enhanced Electrocatalytic Activity of Iron Amino Porphyrins Using a Flow Cell for Reduction of CO2 to CO","volume":"58","author":"Abdinejad","year":"2021","journal-title":"J. Energy Chem."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"8315","DOI":"10.1021\/jacs.9b02640","article-title":"Mechanism of Catalytic O2 Reduction by Iron Tetraphenylporphyrin","volume":"141","author":"Pegis","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1021\/jacs.6b10140","article-title":"Influence of Anion Delocalization on Electron Transfer in a Covalent Porphyrin Donor-Perylenediimide Dimer Acceptor System","volume":"139","author":"Hartnett","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"13415","DOI":"10.1021\/acsami.6b16423","article-title":"Highly Fluorescent Polyimide Covalent Organic Nanosheets as Sensing Probes for the Detection of 2,4,6-Trinitrophenol","volume":"9","author":"Zhang","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.snb.2018.08.097","article-title":"Porphyrin-Based Porous Organic Framework: An Efficient and Stable Peroxidase-Mimicking Nanozyme for Detection of H2O2 and Evaluation of Antioxidant","volume":"277","author":"Cui","year":"2018","journal-title":"Sens. Actuators, B"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1007\/s00604-015-1506-8","article-title":"A Cu2(OH)3Cl-CeO2 Nanocomposite with Peroxidase-Like Activity, and Its Application to the Determination of Hydrogen Peroxide, Glucose and Cholesterol","volume":"182","author":"Wang","year":"2015","journal-title":"Microchim. Acta"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.talanta.2015.11.023","article-title":"Graphene Oxide vs. Reduced Graphene Oxide as Carbon Support in Porphyrin Peroxidase Biomimetic Nanomaterials","volume":"148","author":"Socaci","year":"2016","journal-title":"Talanta"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"66963","DOI":"10.1039\/C6RA16619A","article-title":"Sphere-Like CoS with Nanostructures as Peroxidase Mimics for Colorimetric Determination of H2O2 and Mercury Ions","volume":"6","author":"Yang","year":"2016","journal-title":"RSC Adv."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.snb.2016.09.049","article-title":"One-Step Synthesis of Uniform Nanoparticles of Porphyrin Functionalized Ceria with Promising Peroxidase Mimetics for H2O2 and Glucose Colorimetric Detection","volume":"240","author":"Liu","year":"2017","journal-title":"Sens. Actuators, B"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"130104","DOI":"10.1016\/j.snb.2021.130104","article-title":"Rapid and Highly Sensitive Colorimetric Biosensor For the Detection of Glucose and Hydrogen Peroxide Based on Nanoporphyrin Combined with Bromine as a Peroxidase-Like Catalyst","volume":"343","author":"Chen","year":"2021","journal-title":"Sens. Actuators, B"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1016\/j.bios.2010.08.019","article-title":"Biomolecule-Stabilized Au Nanoclusters as a Fluorescence Probe for Sensitive Detection of Glucose","volume":"26","author":"Jin","year":"2011","journal-title":"Biosens. Bioelectron."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ab.2013.10.005","article-title":"A Mediator-Free Glucose Biosensor Based on Glucose Oxidase\/Chitosan\/Alpha-Zirconium Phosphate Ternary Biocomposite","volume":"445","author":"Liu","year":"2014","journal-title":"Anal. Biochem."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"111577","DOI":"10.1016\/j.bios.2019.111577","article-title":"One-Step Electrodeposition of AuNi Nanodendrite Arrays as Photoelectrochemical Biosensors for Glucose and Hydrogen Peroxide Detection","volume":"142","author":"Wang","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.1016\/j.bios.2011.01.044","article-title":"Nonenzymatic Amperometric Response of Glucose on A Nanoporous Gold Film Electrode Fabricated by A Rapid and Simple Electrochemical Method","volume":"26","author":"Xia","year":"2011","journal-title":"Biosens. Bioelectron."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"120302","DOI":"10.1016\/j.talanta.2019.120302","article-title":"Development of The Simultaneous Colorimetric Enzymatic Detection of Sucrose, Fructose and Glucose Using a Microfluidic Paper-based Analytical Device","volume":"207","author":"Aksorn","year":"2020","journal-title":"Talanta"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.bios.2016.08.026","article-title":"Size-Selective QD@MOF Core-Shell Nanocomposites for the Highly Sensitive Monitoring of Oxidase Activities","volume":"87","author":"Wang","year":"2017","journal-title":"Biosens. Bioelectron."}],"container-title":["Biosensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-6374\/13\/2\/188\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:16:13Z","timestamp":1760120173000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-6374\/13\/2\/188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,26]]},"references-count":59,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["bios13020188"],"URL":"https:\/\/doi.org\/10.3390\/bios13020188","relation":{},"ISSN":["2079-6374"],"issn-type":[{"value":"2079-6374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,26]]}}}