{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T09:54:37Z","timestamp":1775814877162,"version":"3.50.1"},"reference-count":116,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004366","name":"Tabriz University of Medical Sciences","doi-asserted-by":"publisher","award":["68628"],"award-info":[{"award-number":["68628"]}],"id":[{"id":"10.13039\/501100004366","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biosensors"],"abstract":"<jats:p>Listeria monocytogenes (L.M.) is a gram-positive bacillus with wide distribution in the environment. This bacterium contaminates water sources and food products and can be transmitted to the human population. The infection caused by L.M. is called listeriosis and is common in pregnant women, immune-deficient patients, and older adults. Based on the released statistics, listeriosis has a high rate of hospitalization and mortality; thus, rapid and timely detection of food contamination and listeriosis cases is necessary. During the last few decades, biosensors have been used for the detection and monitoring of varied bacteria species. These devices are detection platforms with great sensitivity and low detection limits. Among different types of biosensors, electrochemical biosensors have a high capability to circumvent several drawbacks associated with the application of conventional laboratory techniques. In this review article, different electrochemical biosensor types used for the detection of listeriosis were discussed in terms of actuators, bioreceptors, specific working electrodes, and signal amplification. We hope that this review will facilitate researchers to access a complete and comprehensive template for pathogen detection based on the different formats of electrochemical biosensors.<\/jats:p>","DOI":"10.3390\/bios13020216","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T02:21:12Z","timestamp":1675304472000},"page":"216","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Electrochemical Biosensors as a Novel Platform in the Identification of Listeriosis Infection"],"prefix":"10.3390","volume":"13","author":[{"given":"Leila","family":"Mehrannia","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz 51666-14733, Iran"},{"name":"Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz 51666-14733, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2262-6453","authenticated-orcid":false,"given":"Balal","family":"Khalilzadeh","sequence":"additional","affiliation":[{"name":"Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz 51666-14733, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Rahbarghazi","sequence":"additional","affiliation":[{"name":"Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz 51666-14733, Iran"},{"name":"Department of Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz 51666-14733, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morteza","family":"Milani","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz 51666-14733, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gulsah","family":"Saydan Kanberoglu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science, Van Yuzuncu Yil University, Van 65080, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadi","family":"Yousefi","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Sciences, Khoy University of Medical Sciences, Khoy 58167-53464, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevin","family":"Erk","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, Ankara 06560, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.2147\/NDD.S64847","article-title":"Enzyme-based electrochemical biosensors for food safety: A review","volume":"2016","author":"Kumar","year":"2016","journal-title":"Nanobiosensors Dis. Diagn."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1007\/s00604-019-3966-8","article-title":"Recent progress in nanomaterial-based electrochemical biosensors for pathogenic bacteria","volume":"186","author":"Pourakbari","year":"2019","journal-title":"Microchim. Acta"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0168-1605(02)00232-5","article-title":"Emerging foodborne pathogens","volume":"78","author":"Tauxe","year":"2002","journal-title":"Int. J. Food Microbiol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Sidhu, R.K., Cavallaro, N.D., Pola, C.C., Danyluk, M.D., McLamore, E.S., and Gomes, C.L. (2020). Planar Interdigitated Aptasensor for Flow-Through Detection of Listeria spp. in Hydroponic Lettuce Growth Media. Sensors, 20.","DOI":"10.3390\/s20205773"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"101092","DOI":"10.1016\/j.nantod.2021.101092","article-title":"Point-of-care diagnostics for infectious diseases: From methods to devices","volume":"37","author":"Wang","year":"2021","journal-title":"Nano Today"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1109\/JMEMS.2005.845444","article-title":"Impedance microbiology-on-a-chip: Microfluidic bioprocessor for rapid detection of bacterial metabolism","volume":"14","author":"Morisette","year":"2005","journal-title":"J. Microelectromech. Syst."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s12161-017-0991-2","article-title":"A Minireview of the Methods for Listeria monocytogenes Detection","volume":"11","author":"Liu","year":"2018","journal-title":"Food Anal. Methods"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1039\/C7AN02039B","article-title":"Actuation of chitosan-aptamer nanobrush borders for pathogen sensing","volume":"143","author":"Hills","year":"2018","journal-title":"Analyst"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1080\/03067319.2019.1674502","article-title":"Evolving techniques for the detection of Listeria monocytogenes: Underlining the electrochemical approach","volume":"100","author":"Mishra","year":"2020","journal-title":"Int. J. Environ. Anal. Chem."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"113375","DOI":"10.1016\/j.bios.2021.113375","article-title":"A MoS2 platform and thionine-carbon nanodots for sensitive and selective detection of pathogens","volume":"189","author":"Sulleiro","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"9412","DOI":"10.1021\/ac502335g","article-title":"Potentiometric Aptasensing of Listeria monocytogenes Using Protamine as an Indicator","volume":"86","author":"Ding","year":"2014","journal-title":"Anal. Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.mimet.2005.10.007","article-title":"Detection of Listeria monocytogenes and the toxin listeriolysin O in food","volume":"64","author":"Churchill","year":"2006","journal-title":"J. Microbiol. Methods"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/s13052-018-0595-5","article-title":"Listeria monocytogenes meningitis in immunocompetent and healthy children: A case report and a review of the literature","volume":"44","author":"Castellazzi","year":"2018","journal-title":"Ital. J. Pediatr."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.3389\/fmicb.2019.02959","article-title":"Rapid and Specific Detection of Listeria monocytogenes With an Isothermal Amplification and Lateral Flow Strip Combined Method That Eliminates False-Positive Signals From Primer\u2013Dimers","volume":"10","author":"Wang","year":"2020","journal-title":"Front. Microbiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"121834","DOI":"10.1016\/j.jchromb.2019.121834","article-title":"Development of a duplex lateral flow dipstick test for the detection and differentiation of Listeria spp. and Listeria monocytogenes in meat products based on loop-mediated isothermal amplification","volume":"1139","author":"Ledlod","year":"2020","journal-title":"J. Chromatogr. B"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"012032","DOI":"10.1088\/1757-899X\/743\/1\/012032","article-title":"Aluminium Interdigitated Electrode Based Biosensor for Specific ssDNA Target Listeria Detection","volume":"743","author":"Jambek","year":"2020","journal-title":"IOP Conf. Ser. Mater. Sci. Eng."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"114980","DOI":"10.1016\/j.bios.2022.114980","article-title":"Electrochemical biosensors in exosome analysis; a short journey to the present and future trends in early-stage evaluation of cancers","volume":"222","author":"Dezhakam","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"116696","DOI":"10.1016\/j.trac.2022.116696","article-title":"Electrochemical biosensors for stem cell analysis; applications in diagnostics, differentiation and follow-up","volume":"156","author":"Nasrollahpour","year":"2022","journal-title":"TrAC Trends Anal. Chem."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"014601","DOI":"10.1149\/2754-2726\/ac5fb3","article-title":"A Smartphone Operated Electrochemical Reader and Actuator that Streamlines the Operation of Electrochemical Biosensors","volume":"1","author":"Scott","year":"2022","journal-title":"ECS Sens. Plus"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"107633","DOI":"10.1016\/j.bioelechem.2020.107633","article-title":"Gold nanostar-enhanced electrochemiluminescence immunosensor for highly sensitive detection of cancer stem cells using CD133 membrane biomarker","volume":"137","author":"Chenaghlou","year":"2021","journal-title":"Bioelectrochemistry"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00604-019-3882-y","article-title":"Electrochemiluminescence methods using CdS quantum dots in aptamer-based thrombin biosensors: A comparative study","volume":"187","author":"Isildak","year":"2020","journal-title":"Microchim. Acta"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.ijbiomac.2019.05.061","article-title":"Development of a reliable microRNA based electrochemical genosensor for monitoring of miR-146a, as key regulatory agent of neurodegenerative disease","volume":"134","author":"Khalilzadeh","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"111916","DOI":"10.1016\/j.bios.2019.111916","article-title":"Design a highly specific sequence for electrochemical evaluation of meat adulteration in cooked sausages","volume":"150","author":"Mansouri","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12645-021-00082-y","article-title":"Ultrasensitive bioassaying of HER-2 protein for diagnosis of breast cancer using reduced graphene oxide\/chitosan as nanobiocompatible platform","volume":"12","author":"Nasrollahpour","year":"2021","journal-title":"Cancer Nanotechnol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"113023","DOI":"10.1016\/j.bios.2021.113023","article-title":"A highly sensitive electrochemiluminescence cytosensor for detection of SKBR-3 cells as metastatic breast cancer cell line: A constructive phase in early and precise diagnosis","volume":"178","author":"Nasrollahpour","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"3020","DOI":"10.1016\/j.ijbiomac.2020.10.191","article-title":"Multiplex bioassaying of cancer proteins and biomacromolecules: Nanotechnological, structural and technical perspectives","volume":"165","author":"Karimzadeh","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1021\/acs.analchem.1c03909","article-title":"Homogeneous Electrochemiluminescence in the Sensors Game: What Have We Learned from Past Experiments?","volume":"94","author":"Nasrollahpour","year":"2021","journal-title":"Anal. Chem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"112552","DOI":"10.1016\/j.bios.2020.112552","article-title":"Recent advances in developing biosensing based platforms for neonatal sepsis","volume":"169","author":"Balayan","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2012.12.004","article-title":"The enzyme thermistor\u2014A realistic biosensor concept. A critical review","volume":"766","author":"Yakovleva","year":"2013","journal-title":"Anal. Chim. Acta"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"113073","DOI":"10.1016\/j.bios.2021.113073","article-title":"An ultrasensitive CRISPR\/Cas12a based electrochemical biosensor for Listeria monocytogenes detection","volume":"179","author":"Li","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1002\/bio.1344","article-title":"Determination of deferiprone in urine and serum using a terbium-sensitized luminescence method","volume":"27","author":"Manzoori","year":"2012","journal-title":"Luminescence"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1080\/00032719.2022.2057525","article-title":"Electrodeposition of Cerium Oxide Nanoparticles on the Graphenized Carbon Ceramic Electrode (GCCE) for the Sensitive Determination of Isoprenaline in Human Serum by Differential Pulse Voltammetry (DPV)","volume":"55","author":"Shafaei","year":"2022","journal-title":"Anal. Lett."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"115834","DOI":"10.1016\/j.trac.2020.115834","article-title":"The role of nanomaterials on the cancer cells sensing based on folate receptor: Analytical approach","volume":"125","author":"Soleymani","year":"2020","journal-title":"TrAC Trends Anal. Chem."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Rozenblum, G.T., Pollitzer, I.G., and Radrizzani, M. (2019). Challenges in Electrochemical Aptasensors and Current Sensing Architectures Using Flat Gold Surfaces. Chemosensors, 7.","DOI":"10.3390\/chemosensors7040057"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Radhakrishnan, R., and Poltronieri, P. (2017). Label Free Biosensor Methods in Detection of Food Pathogens and Listeria monocytogenes. Preprints, 2017100094.","DOI":"10.20944\/preprints201710.0094.v1"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1021\/acssensors.6b00333","article-title":"Quantitative Label-Free Listeria Analysis Based On Aptamer Modified Nanoporous Sensor","volume":"1","author":"Zhou","year":"2016","journal-title":"ACS Sens."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s40828-015-0016-y","article-title":"Voltammetric techniques of analysis: The essentials","volume":"1","author":"Scholz","year":"2015","journal-title":"ChemTexts"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"13600","DOI":"10.1021\/acs.analchem.8b03809","article-title":"Potentiometric Detection of Listeria monocytogenes via a Short Antimicrobial Peptide Pair-Based Sandwich Assay","volume":"90","author":"Lv","year":"2018","journal-title":"Anal. Chem."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jbiotec.2015.02.025","article-title":"Label-free impedimetric detection of Listeria monocytogenes based on poly-5-carboxy indole modified ssDNA probe","volume":"200","author":"Kashish","year":"2015","journal-title":"J. Biotechnol."},{"key":"ref_40","unstructured":"Luis Jes\u00fas, V.-G., and Ana Leticia, I. (2020). Biosensors, IntechOpen."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"121722","DOI":"10.1016\/j.talanta.2020.121722","article-title":"Recent improvements in enzyme-linked immunosorbent assays based on nanomaterials","volume":"223","author":"Zhao","year":"2021","journal-title":"Talanta"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.bios.2015.06.007","article-title":"A sensitive impedance biosensor based on immunomagnetic separation and urease catalysis for rapid detection of Listeria monocytogenes using an immobilization-free interdigitated array microelectrode","volume":"74","author":"Chen","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"ref_43","first-page":"49","article-title":"A Cell-Based Biosensor System for Listeria monocytogenes Detection in Food","volume":"60","author":"Hadjilouka","year":"2020","journal-title":"Proceedings"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"29302","DOI":"10.1039\/C7RA03778C","article-title":"Development of a pigment-based whole-cell biosensor for the analysis of environmental copper","volume":"7","author":"Chen","year":"2017","journal-title":"RSC Adv."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"120976","DOI":"10.1016\/j.talanta.2020.120976","article-title":"Electrochemical immunosensor towards invasion-associated protein p60: An alternative strategy for Listeria monocytogenes screening in food","volume":"216","author":"Silva","year":"2020","journal-title":"Talanta"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"3895920","DOI":"10.1155\/2016\/3895920","article-title":"A Novel and Disposable Enzyme-Labeled Amperometric Immunosensor Based on MWCNT Fibers for Listeria monocytogenes Detection","volume":"2016","author":"Lu","year":"2016","journal-title":"J. Nanomater."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0003-2670(02)01033-4","article-title":"Coupling conducting polymers and mediated electrochemical responses for the detection of Listeria","volume":"475","author":"Minett","year":"2003","journal-title":"Anal. Chim. Acta"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0956-5663(02)00214-2","article-title":"Demonstration of labeless detection of food pathogens using electrochemical redox probe and screen printed gold electrodes","volume":"18","author":"Susmel","year":"2003","journal-title":"Biosens. Bioelectron."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.foodcont.2016.09.003","article-title":"Efficient separation and quantitative detection of Listeria monocytogenes based on screen-printed interdigitated electrode, urease and magnetic nanoparticles","volume":"73","author":"Wang","year":"2017","journal-title":"Food Control"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.4315\/0362-028X.JFP-11-516","article-title":"Efficient separation and sensitive detection of Listeria monocytogenes using an impedance immunosensor based on magnetic nanoparticles, a microfluidic chip, and an interdigitated microelectrode","volume":"75","author":"Kanayeva","year":"2012","journal-title":"J. Food Prot."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Hadjilouka, A., Loizou, K., Apostolou, T., Dougiakis, L., Inglezakis, A., and Tsaltas, D. (2020). Newly developed system for the robust detection of Listeria monocytogenes based on a bioelectric cell biosensor. Biosensors, 10.","DOI":"10.3390\/bios10110178"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.snb.2013.09.041","article-title":"Rapid detection of Listeria monocytogenes in milk by self-assembled electrochemical immunosensor","volume":"190","author":"Cheng","year":"2014","journal-title":"Sens. Actuators B Chem."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.bios.2007.09.011","article-title":"The development of a \u2018labeless\u2019 immunosensor for the detection of Listeria monocytogenes cell surface protein, Internalin B","volume":"23","author":"Tully","year":"2008","journal-title":"Biosens. Bioelectron."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1021\/nl080366q","article-title":"TiO2 nanowire bundle microelectrode based impedance immunosensor for rapid and sensitive detection of Listeria monocytogenes","volume":"8","author":"Wang","year":"2008","journal-title":"Nano Lett."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1002\/elan.201300140","article-title":"Detection of Listeria monocytogenes by electrochemical impedance spectroscopy","volume":"25","author":"Radhakrishnan","year":"2013","journal-title":"Electroanalysis"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1049\/iet-nbt.2020.0091","article-title":"Development of magnetosomes-based biosensor for the detection of Listeria monocytogenes from food sample","volume":"14","author":"Sannigrahi","year":"2020","journal-title":"IET Nanobiotechnol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1089\/ind.2012.0033","article-title":"Gold Nanoparticle-Modified Carbon Electrode Biosensor for the Detection of Listeria monocytogenes","volume":"9","author":"Davis","year":"2013","journal-title":"Ind. Biotechnol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"5749","DOI":"10.1039\/c2an35988j","article-title":"A bacteriophage endolysin-based electrochemical impedance biosensor for the rapid detection of Listeria cells","volume":"137","author":"Tolba","year":"2012","journal-title":"Analyst"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"4916","DOI":"10.3390\/s19224916","article-title":"Review of Electrochemical DNA Biosensors for Detecting Food Borne Pathogens","volume":"19","author":"Wu","year":"2019","journal-title":"Sensors"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.bios.2013.06.033","article-title":"Synergizing nucleic acid aptamers with 1-dimensional nanostructures as label-free field-effect transistor biosensors","volume":"50","author":"Narducci","year":"2013","journal-title":"Biosens. Bioelectron."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/elsc.202100148","article-title":"Aptasensors versus immunosensors\u2014Which will prevail?","volume":"22","author":"Heuer","year":"2022","journal-title":"Eng. Life Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"11081","DOI":"10.1021\/acs.inorgchem.1c00952","article-title":"Reversible Structural Transformation of CuI\u2013TbIII Heterometallic MOFs with Highly Efficient Detection Capability toward Penicillin","volume":"60","author":"Xue","year":"2021","journal-title":"Inorg. Chem."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"113449","DOI":"10.1016\/j.ab.2019.113449","article-title":"Label-free lateral flow assay for Listeria monocytogenes by aptamer-gated release of signal molecules","volume":"587","author":"Tasbasi","year":"2019","journal-title":"Anal. Biochem."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"21413","DOI":"10.1038\/s41598-022-25753-7","article-title":"Rapid and label-free Listeria monocytogenes detection based on stimuli-responsive alginate-platinum thiomer nanobrushes","volume":"12","author":"Oliveira","year":"2022","journal-title":"Sci. Rep."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"107414","DOI":"10.1016\/j.microc.2022.107414","article-title":"A novel aptamer biosensor using ZnO-3DNGH for sensitive and selective detection of Listeria monocytogenes","volume":"179","author":"Chen","year":"2022","journal-title":"Microchem. J."},{"key":"ref_66","first-page":"28","article-title":"DNA Biosensors Techniques and Their Applications in Food Safety, Environmental Protection and Biomedical Research: A mini-review","volume":"3","author":"Vahideh","year":"2020","journal-title":"J. Cell Dev. Biol."},{"key":"ref_67","first-page":"353","article-title":"Electrochemical Genosensors: Definition and Fields of Application","volume":"3","year":"2017","journal-title":"Int. J. Biosens. Bioelectron."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.3390\/s8042118","article-title":"Application of DNA Hybridization Biosensor as a Screening Method for the Detection of Genetically Modified Food Components","volume":"8","author":"Tichoniuk","year":"2008","journal-title":"Sensors"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1039\/C5AY00167F","article-title":"Genosensor based on a nanostructured, platinum-modified glassy carbon electrode for Listeria detection","volume":"7","author":"Kashish","year":"2015","journal-title":"Anal. Methods"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"7708","DOI":"10.1021\/acs.analchem.0c00669","article-title":"Electrochemical Cloth-Based DNA Sensors (ECDSs): A New Class of Electrochemical Gene Sensors","volume":"92","author":"Jiang","year":"2020","journal-title":"Anal. Chem."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2015.09.044","article-title":"Electrochemical genosensing of Salmonella, Listeria and Escherichia coli on silica magnetic particles","volume":"904","author":"Campoy","year":"2016","journal-title":"Anal. Chim. Acta"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"640163","DOI":"10.1155\/2013\/640163","article-title":"An internalin a probe-based genosensor for Listeria monocytogenes detection and differentiation","volume":"2013","author":"Bifulco","year":"2013","journal-title":"BioMed Res. Int."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Wu, L., Liu, Q., Wu, Z., and Lu, Z. (2008, January 16\u201318). Detection of hlyA Gene of Listeria monocytogenes with Electrochemical DNA Biosensor. Proceedings of the 2008 2nd International Conference on Bioinformatics and Biomedical Engineering, Shanghai, China.","DOI":"10.1109\/ICBBE.2008.95"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jelechem.2006.04.015","article-title":"Development of disposable low density screen-printed electrode arrays for simultaneous electrochemical measurements of the hybridisation reaction","volume":"593","author":"Laschi","year":"2006","journal-title":"J. Electroanal. Chem."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.electacta.2012.07.133","article-title":"Electrochemical DNA biosensor for the detection of Listeria monocytogenes with dendritic nanogold and electrochemical reduced graphene modified carbon ionic liquid electrode","volume":"85","author":"Sun","year":"2012","journal-title":"Electrochim. Acta"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jelechem.2017.10.049","article-title":"Electrochemical DNA biosensor based on gold nanoparticles and partially reduced graphene oxide modified electrode for the detection of Listeria monocytogenes hly gene sequence","volume":"806","author":"Niu","year":"2017","journal-title":"J. Electroanal. Chem."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/BF03245868","article-title":"Electrochemical DNA biosensor for the detection of Listeria monocytogenes using toluidine blue as a hybridization indicator","volume":"7","author":"Gao","year":"2010","journal-title":"J. Iran. Chem. Soc."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"4086","DOI":"10.20964\/2017.05.04","article-title":"Electrochemical DNA Sensor for hly gene of Listeria monocytogenes by three-dimensional graphene and gold nanocomposite modified electrode","volume":"12","author":"Yan","year":"2017","journal-title":"Int. J. Electrochem."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s13205-020-02315-0","article-title":"PlcA-based nanofabricated electrochemical DNA biosensor for the detection of Listeria monocytogenes in raw milk samples","volume":"10","author":"Saini","year":"2020","journal-title":"3 Biotech"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"2710","DOI":"10.1021\/ac0521100","article-title":"Redox polymer and probe DNA tethered to gold electrodes for enzyme-amplified amperometric detection of DNA hybridization","volume":"78","author":"Kavanagh","year":"2006","journal-title":"Anal. Chem."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1039\/C9AN01897B","article-title":"Ultrasensitive electrochemical DNA biosensor based on a tetrahedral structure and proximity-dependent surface hybridization","volume":"145","author":"Wang","year":"2020","journal-title":"Analyst"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"20180087","DOI":"10.1098\/rstb.2018.0087","article-title":"Origins and evolution of CRISPR-Cas systems","volume":"374","author":"Koonin","year":"2019","journal-title":"Philos. Trans. R. Soc. B"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.tplants.2019.09.006","article-title":"CRISPR\/Cas system: Recent advances and future prospects for genome editing","volume":"24","author":"Manghwar","year":"2019","journal-title":"Trends Plant Sci."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"513","DOI":"10.3389\/fphar.2019.00513","article-title":"Advantages and limitations of bacteriophages for the treatment of bacterial infections","volume":"10","author":"Principi","year":"2019","journal-title":"Front. Pharmacol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s12645-022-00113-2","article-title":"Early stage evaluation of colon cancer using tungsten disulfide quantum dots and bacteriophage nano-biocomposite as an efficient electrochemical platform","volume":"13","author":"Pourakbari","year":"2022","journal-title":"Cancer Nanotechnol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"067510","DOI":"10.1149\/1945-7111\/ac7a63","article-title":"Electrochemical Biosensor for Rapid Detection of Listeria monocytogenes","volume":"169","author":"Zolti","year":"2022","journal-title":"J. Electrochem. Soc."},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Rajapaksha, A., Hashim, U., Natasha, N.Z., Uda, M.N., Vijayakumaran, T., and Fernando, C.A. (2017, January 23\u201325). Gold nano-particle based Al interdigitated electrode electrical biosensor for specific ssDNA target detection. Proceedings of the 2017 IEEE Regional Symposium on Micro and Nanoelectronics (RSM), Batu Ferringhi, Malaysia.","DOI":"10.1109\/RSM.2017.8069167"},{"key":"ref_88","first-page":"77","article-title":"Impedance biosensor for the rapid detection of Listeria spp. based on aptamer functionalized Pt-interdigitated microelectrodes array","volume":"9863","author":"Sidhu","year":"2016","journal-title":"SPIE"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1039\/D1AY01570B","article-title":"Applications of electrochemical biosensors based on functional antibody-modified screen-printed electrodes: A review","volume":"14","author":"Wang","year":"2022","journal-title":"Anal. Methods"},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"Bridier, A. (2019). Foodborne Bacterial Pathogens: Methods and Protocols, Springer.","DOI":"10.1007\/978-1-4939-9000-9"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.bios.2016.07.071","article-title":"Fast and sensitive detection of foodborne pathogen using electrochemical impedance analysis, urease catalysis and microfluidics","volume":"86","author":"Chen","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"113739","DOI":"10.1016\/j.bios.2021.113739","article-title":"Development of the DNA-based biosensors for high performance in detection of molecular biomarkers: More rapid, sensitive, and universal","volume":"197","author":"Wang","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s00339-014-8340-4","article-title":"Nano-and femtosecond UV laser pulses to immobilize biomolecules onto surfaces with preferential orientation","volume":"117","author":"Lettieri","year":"2014","journal-title":"Appl. Phys. A"},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Radhakrishnan, R., and Poltronieri, P. (2017). Fluorescence-Free Biosensor Methods in Detection of Food Pathogens with a Special Focus on Listeria monocytogenes. Biosensors, 7.","DOI":"10.20944\/preprints201710.0094.v1"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.bios.2009.09.020","article-title":"An enzyme-amplified amperometric DNA hybridisation assay using DNA immobilised in a carboxymethylated dextran film anchored to a graphite surface","volume":"25","author":"Hajdukiewicz","year":"2010","journal-title":"Biosens. Bioelectron."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"5073","DOI":"10.1109\/JSEN.2018.2828416","article-title":"Performance of carbon nano-scale allotropes in detecting midazolam and paracetamol in undiluted human serum","volume":"18","author":"Aliakbarinodehi","year":"2018","journal-title":"IEEE Sens. J."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"105123","DOI":"10.1016\/j.chemphyslip.2021.105123","article-title":"Preparation, physicochemical characterization, and anti-proliferative properties of Lawsone-loaded solid lipid nanoparticles","volume":"239","author":"Rasouliyan","year":"2021","journal-title":"Chem. Phys. Lipids"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"31065","DOI":"10.1016\/j.ceramint.2022.05.037","article-title":"Halloysite clay nanotube in regenerative medicine for tissue and wound healing","volume":"48","author":"Same","year":"2022","journal-title":"Ceram. Int."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1080\/10837450.2021.1963276","article-title":"Acriflavine-loaded solid lipid nanoparticles: Preparation, physicochemical characterization, and anti-proliferative properties","volume":"26","author":"Vandghanooni","year":"2021","journal-title":"Pharm. Dev. Technol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"108916","DOI":"10.1016\/j.foodcont.2022.108916","article-title":"Gold core @ platinum shell nanozyme-mediated magnetic relaxation switching DNA sensor for the detection of Listeria monocytogenes in chicken samples","volume":"137","author":"Wu","year":"2022","journal-title":"Food Control"},{"key":"ref_101","doi-asserted-by":"crossref","unstructured":"El Aamri, M., Yammouri, G., Mohammadi, H., Amine, A., and Korri-Youssoufi, H. (2020). Electrochemical biosensors for detection of microRNA as a cancer biomarker: Pros and cons. Biosensors, 10.","DOI":"10.3390\/bios10110186"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.snb.2018.08.132","article-title":"A novel AuNPs-doped COFs composite as electrochemical probe for chlorogenic acid detection with enhanced sensitivity and stability","volume":"276","author":"Zhang","year":"2018","journal-title":"Sens. Actuators B Chem."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.snb.2018.11.032","article-title":"Ratiometric electrochemical sensing and biosensing based on multiple redox-active state COFDHTA-TTA","volume":"281","author":"Xu","year":"2019","journal-title":"Sens. Actuators B Chem."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1016\/j.cclet.2021.02.042","article-title":"Artful union of a zirconium-porphyrin MOF\/GO composite for fabricating an aptamer-based electrochemical sensor with superb detecting performance","volume":"32","author":"Li","year":"2021","journal-title":"Chin. Chem. Lett."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"129144","DOI":"10.1016\/j.snb.2020.129144","article-title":"Crystal engineering of MOF@ COF core-shell composites for ultra-sensitively electrochemical detection","volume":"329","author":"Zhang","year":"2021","journal-title":"Sens. Actuators B Chem."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"122026","DOI":"10.1016\/j.talanta.2020.122026","article-title":"Nanomaterial application in bio\/sensors for the detection of infectious diseases","volume":"230","author":"Sheikhzadeh","year":"2021","journal-title":"Talanta"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.snb.2006.11.016","article-title":"Electrochemical nanobiosensors","volume":"123","author":"Pumera","year":"2007","journal-title":"Sens. Actuators B Chem."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1007\/s00604-019-3321-0","article-title":"Metal organic frameworks in electrochemical and optical sensing platforms: A review","volume":"186","author":"Anik","year":"2019","journal-title":"Microchim. Acta"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1080\/10408347.2018.1561243","article-title":"Carbon nanomaterial-based electrochemical biosensors for foodborne bacterial detection","volume":"49","author":"Muniandy","year":"2019","journal-title":"Crit. Rev. Anal. Chem."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"15328","DOI":"10.1039\/D0RA01068E","article-title":"Progress in the functional modification of graphene\/graphene oxide: A review","volume":"10","author":"Yu","year":"2020","journal-title":"RSC Adv."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"50166","DOI":"10.1039\/C7RA09878B","article-title":"Electrostatically driven scalable synthesis of mos 2\u2013graphene hybrid films assisted by hydrophobins","volume":"7","author":"Kaur","year":"2017","journal-title":"Rsc Adv."},{"key":"ref_112","first-page":"14","article-title":"Rapid detection of Listeria spp. using an internalin A aptasensor based on carbon-metal nanohybrid structures","volume":"9487","author":"Vanegas","year":"2015","journal-title":"SPIE"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1021\/acsfoodscitech.1c00124","article-title":"Enzyme-Free Multiplex Detection of Foodborne Pathogens Using Au Nanoparticles-Decorated Multiwalled Carbon Nanotubes","volume":"1","author":"Suganya","year":"2021","journal-title":"ACS Food Sci. Technol."},{"key":"ref_114","doi-asserted-by":"crossref","unstructured":"Mishra, A., Pilloton, R., Jain, S., Roy, S., Khanuja, M., Mathur, A., and Narang, J. (2022). Paper-Based Electrodes Conjugated with Tungsten Disulfide Nanostructure and Aptamer for Impedimetric Detection of Listeria monocytogenes. Biosensors, 12.","DOI":"10.3390\/bios12020088"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.aca.2020.07.078","article-title":"Development of a DNA-based biosensor for the fast and sensitive detection of ochratoxin A in urine","volume":"1133","author":"Santovito","year":"2020","journal-title":"Anal. Chim. Acta"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"7306","DOI":"10.4081\/mr.2017.7306","article-title":"Comparison between molecular methods (PCR vs LAMP) to detect Candida albicans in bronchoalveolar lavage samples of suspected tuberculosis patients","volume":"8","author":"Goodarzi","year":"2018","journal-title":"Microbiol. Res."}],"container-title":["Biosensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-6374\/13\/2\/216\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:21:22Z","timestamp":1760120482000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-6374\/13\/2\/216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,1]]},"references-count":116,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["bios13020216"],"URL":"https:\/\/doi.org\/10.3390\/bios13020216","relation":{},"ISSN":["2079-6374"],"issn-type":[{"value":"2079-6374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,1]]}}}