{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:28:27Z","timestamp":1788348507484,"version":"build-2803163510"},"reference-count":135,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T00:00:00Z","timestamp":1782604800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002767","name":"Hunan Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["2026JJ30007"],"award-info":[{"award-number":["2026JJ30007"]}],"id":[{"id":"10.13039\/501100002767","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002767","name":"Hunan Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["2023JJ40463"],"award-info":[{"award-number":["2023JJ40463"]}],"id":[{"id":"10.13039\/501100002767","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hunan Provincial Department of Education","award":["19A346"],"award-info":[{"award-number":["19A346"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biosensors"],"abstract":"<jats:p>The rapid and sensitive quantification of antibiotic residues in aquatic animals is crucial for ensuring food safety and protecting public health. Electrochemical (bio)sensors show great potential in this field due to their quick response time, low cost, and ease of miniaturization. This paper presents a systematic review of advances in the electrochemical detection of eight classes of antibiotics: fluoroquinolones, sulfonamides, amphenicols, tetracyclines, nitrofurans, macrolides, aminoglycosides, and \u03b2-lactams in aquatic animal samples. It covers four types of sensors: direct electrochemical sensors, immunosensors, aptasensors, and molecularly imprinted sensors. The review emphasizes the electrochemical behavior of the targets, interface design, recognition elements, signal amplification strategies, and validation using real samples. It also summarizes the sample pretreatment methods for different classes of antibiotics. Finally, the paper analyzes key challenges related to adaptability to complex matrices, consistency in sample preparation, and validation with real-world samples. Additionally, it proposes future directions for development in this field.<\/jats:p>","DOI":"10.3390\/bios16070359","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T05:49:33Z","timestamp":1782712173000},"page":"359","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Electrochemical (Bio)Sensors for Antibiotic Residue Detection in Aquatic Animal Products: A Review"],"prefix":"10.3390","volume":"16","author":[{"given":"Meiqing","family":"Yang","sequence":"first","affiliation":[{"name":"Hunan Provincial Key Laboratory for Molecular Immunity Technology of Aquatic Animal Diseases, College of Life and Environmental Science, Hunan University of Arts and Science, Changde 415000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuhe","family":"Hu","sequence":"additional","affiliation":[{"name":"Hunan Provincial Key Laboratory for Molecular Immunity Technology of Aquatic Animal Diseases, College of Life and Environmental Science, Hunan University of Arts and Science, Changde 415000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suiping","family":"Wang","sequence":"additional","affiliation":[{"name":"Hunan Provincial Key Laboratory for Molecular Immunity Technology of Aquatic Animal Diseases, College of Life and Environmental Science, Hunan University of Arts and Science, Changde 415000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haozi","family":"Lu","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Hunan Institute of Technology, Hengyang 421002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/s41586-021-03917-1","article-title":"Aquatic foods to nourish nations","volume":"598","author":"Golden","year":"2021","journal-title":"Nature"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"8026","DOI":"10.1038\/s41467-024-51965-8","article-title":"Globalization of wild capture and farmed aquatic foods","volume":"15","author":"Gephart","year":"2024","journal-title":"Nat. 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