{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T11:21:33Z","timestamp":1787570493172,"version":"build-2736575974"},"reference-count":80,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biosensors"],"abstract":"<jats:p>Sulfathiazole (STH) pollution has been increasing, with a strong need for a sensitive and selective analysis method. In this paper, a three-component fluorescent sensing platform with Mn2+-doped ZnS quantum dots in a metal\u2013organic framework coated with a surface molecularly imprinted polymer (Mn-ZnS-MOF-MIP) for selective sensing of sulfathiazole is proposed. This synergistic sensor platform combines Mn-ZnS-insensitive emission, MOF-assisted analyte enrichment, and imprinting-based molecular recognition. The sensing platform displays a characteristic turn-off fluorescence with a dominant static quenching mechanism. Under optimal conditions, a broad sensing range with a low detection limit of 13.75 nM can be obtained. Outstanding selectivity among similar sulfonamides, biomolecules, and metal ions were achieved with high reproducibility, stability, and reusability. This sensing platform was shown to analyze sulfathiazole accurately in aqueous samples and blood serum with high recoveries, within the range of 90.00\u2013104.24%, compared to high-performance liquid chromatography methods.<\/jats:p>","DOI":"10.3390\/bios16090459","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T10:07:53Z","timestamp":1787566073000},"page":"459","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Triadic Mn\u2013ZnS\/MOF\/MIP Fluorescent Sensor for Highly Sensitive and Selective Sulfathiazole Detection"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9819-7929","authenticated-orcid":false,"given":"Fatih","family":"Pekdemir","sequence":"first","affiliation":[{"name":"Department of Chemistry, Faculty of Science, Zonguldak B\u00fclent Ecevit University, Zonguldak 67100, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130zzet","family":"Ko\u00e7ak","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Zonguldak B\u00fclent Ecevit University, Zonguldak 67800, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.etap.2014.11.007","article-title":"Sulfathiazole: Analytical methods for quantification in seawater and macroalgae","volume":"39","author":"Leston","year":"2015","journal-title":"Environ. 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