{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T03:34:45Z","timestamp":1773804885763,"version":"3.50.1"},"reference-count":82,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T00:00:00Z","timestamp":1691020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["22-24-20044"],"award-info":[{"award-number":["22-24-20044"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioTech"],"abstract":"<jats:p>Incorporating a variety of microalgae into wastewater treatment is considered an economically viable and environmentally sound strategy. The present work assessed the growth characteristics of Chlorella sorokiniana during cultivation in balanced synthetic media and domestic wastewater. Increasing the NH4+\u2013N concentration to 360 mg L\u22121 and adding extra PO43\u2212\u2013P and SO42\u2212\u2013S (up to 80 and 36 mg L\u22121, respectively) contributed to an increase in the total biomass levels (5.7\u20135.9 g L\u22121) during the cultivation of C. sorokiniana in synthetic media. Under these conditions, the maximum concentrations of chlorophylls and carotenoids were 180 \u00b1 7.5 and 26 \u00b1 1.4 mg L\u22121, respectively. Furthermore, when studying three types of domestic wastewaters, it was noted that only one wastewater contributed to the productive growth of C. sorokiniana, but all wastewaters stimulated an increased accumulation of protein. Finally, the alga, when growing in optimal unsterilized wastewater, showed a maximum specific growth rate of 0.73 day\u22121, a biomass productivity of 0.21 g L\u22121 day\u22121, and 100% NH4+\u2013N removal. These results demonstrate that the tested alga actively adapts to changes in the composition of the growth medium and accumulates high levels of protein in systems with poor-quality water.<\/jats:p>","DOI":"10.3390\/biotech12030053","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T11:23:03Z","timestamp":1691061783000},"page":"53","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Growth Efficiency of Chlorella sorokiniana in Synthetic Media and Unsterilized Domestic Wastewater"],"prefix":"10.3390","volume":"12","author":[{"given":"Svetlana S.","family":"Bulynina","sequence":"first","affiliation":[{"name":"Department of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, 420008 Kazan, Republic of Tatarstan, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elvira E.","family":"Ziganshina","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, 420008 Kazan, Republic of Tatarstan, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayrat M.","family":"Ziganshin","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, 420008 Kazan, Republic of Tatarstan, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.nbt.2020.11.011","article-title":"The role of microalgae in the bioeconomy","volume":"61","author":"Reis","year":"2021","journal-title":"New Biotechnol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1007\/s13205-022-03327-8","article-title":"Recent advances in the bio-application of microalgae-derived biochemical metabolites and development trends of photobioreactor-based culture systems","volume":"12","author":"Khaligh","year":"2022","journal-title":"3 Biotech"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"970028","DOI":"10.3389\/fmicb.2022.970028","article-title":"A review on biodiesel production from microalgae: Influencing parameters and recent advanced technologies","volume":"13","author":"Zhang","year":"2022","journal-title":"Front. 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