{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T01:15:22Z","timestamp":1775178922879,"version":"3.50.1"},"reference-count":67,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T00:00:00Z","timestamp":1585872000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Balancing is a complex task requiring the integration of visual, somatosensory and vestibular inputs. The vestibular system is linked to the hippocampus, a brain structure crucial for spatial orientation. Here we tested the immediate and sustained effects of a one-month-long slackline training program on balancing and orientation abilities as well as on brain volumes in young adults without any prior experience in that skill. On the corrected level, we could not find any interaction effects for brain volumes, but the effect sizes were small to medium. A subsequent within-training-group analysis revealed volumetric increments within the somatosensory cortex and decrements within posterior insula, cerebellum and putamen remained stable over time. No significant interaction effects were observed on the clinical balance and the spatial orientation task two months after the training period (follow-up). We interpret these findings as a shift away from processes crucial for automatized motor output towards processes related to voluntarily controlled movements. The decrease in insular volume in the training group we propose to result from multisensory interaction of the vestibular with the visual and somatosensory systems. The discrepancy between sustained effects in the brain of the training group on the one hand and transient benefits in function on the other may indicate that for the latter to be retained a longer-term practice is required.<\/jats:p>","DOI":"10.3390\/brainsci10040210","type":"journal-article","created":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T05:05:13Z","timestamp":1586149513000},"page":"210","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Which Effects on Neuroanatomy and Path-Integration Survive? Results of a Randomized Controlled Study on Intensive Balance Training"],"prefix":"10.3390","volume":"10","author":[{"given":"Milos","family":"Dordevic","sequence":"first","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany"},{"name":"Center for Behavioral Brain Sciences (CBBS), 39106 Magdeburg, Germany"},{"name":"Neurology Clinic, Otto von Guericke University, 39120 Magdeburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Taubert","sequence":"additional","affiliation":[{"name":"Center for Behavioral Brain Sciences (CBBS), 39106 Magdeburg, Germany"},{"name":"Chair for Training Science \u201cCognition and Motion\u201d, Department Sports Science, Otto von Guericke University, 39104 Magdeburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Riemer","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany"},{"name":"Center for Behavioral Brain Sciences (CBBS), 39106 Magdeburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8513-7043","authenticated-orcid":false,"given":"J\u00f6rn","family":"Kaufmann","sequence":"additional","affiliation":[{"name":"Neurology Clinic, Otto von Guericke University, 39120 Magdeburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"H\u00f6kelmann","sequence":"additional","affiliation":[{"name":"Chair for Training Science \u201cCognition and Motion\u201d, Department Sports Science, Otto von Guericke University, 39104 Magdeburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5483-6423","authenticated-orcid":false,"given":"Notger G.","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany"},{"name":"Center for Behavioral Brain Sciences (CBBS), 39106 Magdeburg, Germany"},{"name":"Neurology Clinic, Otto von Guericke University, 39120 Magdeburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"11670","DOI":"10.1523\/JNEUROSCI.2567-10.2010","article-title":"Dynamic Properties of Human Brain Structure: Learning-Related Changes in Cortical Areas and Associated Fiber Connections","volume":"30","author":"Taubert","year":"2010","journal-title":"J. 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