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However, the brain mechanisms by which these effective interventions in music impact state anxiety remain unknown. Methods: In this study, we selected music with clinical effects for therapy, and 62 subjects were included using the evoked anxiety paradigm. After evoking anxiety with a visual stimulus, all subjects were randomly divided into three groups (listening to happy music, neutral music and a blank stimulus), and EEG signals were acquired. Results: We found that different emotional types of music might have different mechanisms in state anxiety interventions. Neutral music had the effect of alleviating state anxiety. The brain mechanisms supported that neutral music ameliorating state anxiety was associated with decreased power spectral density of the occipital lobe and increased brain functional connectivity between the occipital lobe and frontal lobe. Happy music also had the effect of alleviating state anxiety, and the brain mechanism was associated with enhanced brain functional connectivity between the occipital lobe and right temporal lobe. Conclusions: This study may be important for a deep understanding of the mechanisms associated with state anxiety music interventions and may further contribute to future clinical treatment using nonpharmaceutical interventions.<\/jats:p>","DOI":"10.3390\/brainsci11101332","type":"journal-article","created":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T21:19:32Z","timestamp":1633900772000},"page":"1332","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["The Benefits of Music Listening for Induced State Anxiety: Behavioral and Physiological Evidence"],"prefix":"10.3390","volume":"11","author":[{"given":"Binxin","family":"Huang","sequence":"first","affiliation":[{"name":"The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu 611731, China"},{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoting","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Long","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Ding","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junce","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijia","family":"Guo","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Lu","sequence":"additional","affiliation":[{"name":"The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu 611731, China"},{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manxi","family":"He","sequence":"additional","affiliation":[{"name":"The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu 611731, China"},{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dezhong","family":"Yao","sequence":"additional","affiliation":[{"name":"The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China, Chengdu 611731, China"},{"name":"School of Life Science and Technology, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China"},{"name":"Research Unit of NeuroInformation, Chinese Academy of Medical Sciences, 2019RU035, Chengdu 611731, China"},{"name":"School of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/nrn1429","article-title":"The developmental origins of anxiety","volume":"5","author":"Gross","year":"2004","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/j.pain.0000000000001386","article-title":"Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain","volume":"160","author":"McLaughlin","year":"2019","journal-title":"Pain"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.nicl.2017.12.014","article-title":"The verbal nature of worry in generalized anxiety: Insights from the brain","volume":"17","author":"Makovac","year":"2018","journal-title":"NeuroImage Clin."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.5665\/sleep.2810","article-title":"A Systematic Review Assessing Bidirectionality between Sleep Disturbances, Anxiety, and Depression","volume":"36","author":"Alvaro","year":"2013","journal-title":"Sleep"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1037\/bul0000111","article-title":"Anxiety and depression as bidirectional risk factors for one another: A meta-analysis of longitudinal studies","volume":"143","author":"Jacobson","year":"2017","journal-title":"Psychol. Bull."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1037\/a0022935","article-title":"The Role of Defeat and Entrapment in Depression, Anxiety, and Suicide","volume":"137","author":"Taylor","year":"2011","journal-title":"Psychol. Bull."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1124\/pr.111.005611","article-title":"Integrating optogenetic and pharmacological approaches to study neural circuit function: Current applications and future directions","volume":"65","author":"Stuber","year":"2013","journal-title":"Pharmacol. Rev."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/BF01172650","article-title":"Anxiety reduction following exercise and meditation","volume":"2","author":"Bahrke","year":"1978","journal-title":"Cognit. Ther. Res."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1097\/01.chi.0000127589.57468.bf","article-title":"Cognitive-behavioral psychotherapy for anxiety and depressive disorders in children and adolescents: An evidence-based medicine review","volume":"43","author":"Compton","year":"2004","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Lin, C.-J., Chang, Y.-C., Chang, Y.-H., Hsiao, Y.-H., Lin, H.-H., Liu, S.-J., Chao, C.-A., Wang, H., and Yeh, T.-L. (2019). Music Interventions for Anxiety in Pregnant Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J. Clin. Med., 8.","DOI":"10.3390\/jcm8111884"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1001\/jama.2013.5670","article-title":"Effects of Patient-Directed Music Intervention on Anxiety and Sedative Exposure in Critically Ill Patients Receiving Mechanical Ventilatory Support: A Randomized Clinical Trial","volume":"309","author":"Chlan","year":"2013","journal-title":"JAMA"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Bradt, J., Dileo, C., and Shim, M. (2013). Music interventions for preoperative anxiety. Cochrane Database Syst. Rev.","DOI":"10.1002\/14651858.CD006908.pub2"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/jmt\/17.1.2","article-title":"Degrees of familiar and affective music and their effects on state anxiety","volume":"17","author":"Riegler","year":"1980","journal-title":"J. Music Ther."},{"key":"ref_14","unstructured":"Hodges, D.A. (2008). Bodily responses to music. Oxford Handbook of Music Psychology, OUP."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.neuron.2013.06.016","article-title":"BLA to vHPC inputs modulate anxiety-related behaviors","volume":"79","author":"Beyeler","year":"2013","journal-title":"Neuron"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.neuron.2014.07.026","article-title":"Fear and Safety Engage Competing Patterns of Theta-Gamma Coupling in the Basolateral Amygdala","volume":"83","author":"Stujenske","year":"2014","journal-title":"Neuron"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jad.2018.05.078","article-title":"Abnormal early dynamic individual patterns of functional networks in low gamma band for depression recognition","volume":"238","author":"Bi","year":"2018","journal-title":"J. Affect. Disord."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/nrn4028","article-title":"Neuronal circuits for fear and anxiety-the missing link","volume":"16","author":"Apps","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1126\/science.2784226","article-title":"Neuroanatomical correlates of anticipatory anxiety","volume":"243","author":"Reiman","year":"1989","journal-title":"Science"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"6313","DOI":"10.1523\/JNEUROSCI.5369-06.2007","article-title":"Cerebral blood flow in immediate and sustained anxiety","volume":"27","author":"Hasler","year":"2007","journal-title":"J. Neurosci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000084165","article-title":"Relationship between disgust sensitivity, trait anxiety and brain activity during disgust induction","volume":"51","author":"Schienle","year":"2005","journal-title":"Neuropsychobiology"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/jnr.23926","article-title":"Gender differences in neural correlates of stress-induced anxiety","volume":"95","author":"Seo","year":"2017","journal-title":"J. Neurosci. Res."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.neuroimage.2005.05.053","article-title":"The rewards of music listening: Response and physiological connectivity of the mesolimbic system","volume":"28","author":"Menon","year":"2005","journal-title":"Neuroimage"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/hbm.20180","article-title":"Investigating emotion with music: An fMRI study","volume":"27","author":"Koelsch","year":"2006","journal-title":"Hum. Brain Mapp."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/ar.a.20316","article-title":"Structural and functional neural correlates of music perception","volume":"288","author":"Limb","year":"2006","journal-title":"Anat. Rec. Part A Discov. Mol. Cell. Evol. Biol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.cortex.2019.09.002","article-title":"Auditory deviance detection in the human insula: An intracranial EEG study","volume":"121","author":"Blenkmann","year":"2019","journal-title":"Cortex"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13229-020-00357-y","article-title":"Reduced auditory steady state responses in autism spectrum disorder","volume":"11","author":"Seymour","year":"2020","journal-title":"Mol. Autism"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1038\/npp.2016.17","article-title":"40 Hz auditory steady-state response is a pharmacodynamic biomarker for cortical NMDA receptors","volume":"41","author":"Sivarao","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"669172","DOI":"10.3389\/fneur.2021.669172","article-title":"Musical Hallucinations in Chronic Pain: The Anterior Cingulate Cortex Regulates Internally Generated Percepts","volume":"12","author":"Schmitgen","year":"2021","journal-title":"Front. Neurol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"e07404","DOI":"10.7554\/eLife.07404","article-title":"Acoustic shadows help gleaning bats find prey, but may be defeated by prey acoustic camouflage on rough surfaces","volume":"4","author":"Clare","year":"2015","journal-title":"Elife"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.neuron.2012.10.038","article-title":"Canonical Microcircuits for Predictive Coding","volume":"76","author":"Bastos","year":"2012","journal-title":"Neuron"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3389\/fnhum.2017.00606","article-title":"Dynamic reconfiguration of the supplementary motor area network during imagined music performance","volume":"11","author":"Tanaka","year":"2017","journal-title":"Front. Hum. Neurosci."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Orndorff-Plunkett, F., Singh, F., Arag\u00f3n, O.R., and Pineda, J.A. (2017). Assessing the effectiveness of neurofeedback training in the context of clinical and social neuroscience. Brain Sci., 7.","DOI":"10.3390\/brainsci7080095"},{"key":"ref_34","first-page":"70","article-title":"The International Affective Picture System (IAPS)","volume":"Volume 29","author":"Bradley","year":"2007","journal-title":"Handbook of Emotion Elicitation and Assessment"},{"key":"ref_35","first-page":"39","article-title":"International Affective Picture System (IAPS): Digitized Photographs, Instruction Manual and Affective Ratings","volume":"1","author":"Lang","year":"2005","journal-title":"Tech. Rep."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1080\/02699939508408966","article-title":"Emotion Elicitation using Films","volume":"9","author":"Gross","year":"1995","journal-title":"Cogn. Emot."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Jungkunz, V.G. (2016). The Silence of the Lambs, Sk\u00edfan.","DOI":"10.1515\/9781438459905-008"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1080\/02699930441000436","article-title":"Anxiety and disgust: Evidence for a unidirectional relationship","volume":"19","author":"Marzillier","year":"2005","journal-title":"Cogn. Emot."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.appet.2007.05.004","article-title":"Immediate effects of chocolate on experimentally induced mood states","volume":"49","author":"Macht","year":"2007","journal-title":"Appetite"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1037\/a0013283","article-title":"In the Mood to Get Over Yourself: Mood Affects Theory-of-Mind Use","volume":"8","author":"Converse","year":"2008","journal-title":"Emotion"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-13386-0","article-title":"Music induced happy mood suppresses the neural responses to other\u2019s pain: Evidences from an ERP study","volume":"7","author":"Cheng","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nn1081","article-title":"Swinging in the brain: Shared neural substrates for behaviors related to sequencing and music","volume":"6","author":"Janata","year":"2003","journal-title":"Nat. Neurosci."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1177\/0305735619849622","article-title":"Sad music depresses sad adolescents: A listener\u2019s profile","volume":"49","author":"Canale","year":"2021","journal-title":"Psychol. Music"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"3256","DOI":"10.1007\/s10803-020-04781-0","article-title":"Effects of Emotional Music on Facial Emotion Recognition in Children with Autism Spectrum Disorder (ASD)","volume":"51","author":"Wagener","year":"2021","journal-title":"J. Autism Dev. Disord."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1177\/1943862113482143","article-title":"On a Blue Note: Depressed Peoples\u2019 Reasons for Listening to Music","volume":"5","author":"Wilhelm","year":"2013","journal-title":"Music Med."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Spielberger, C.D. (2010). State-Trait Anxiety Inventory. Corsini Encycl. Psychol., 1.","DOI":"10.1002\/9780470479216.corpsy0943"},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Rammstedt, B., and John, O.P. (2017). Big Five Inventory. Encycl. Personal. Individ. Differ., 1\u20134.","DOI":"10.1007\/978-3-319-28099-8_445-1"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1037\/0022-3514.54.3.466","article-title":"Coping as a Mediator of Emotion","volume":"54","author":"Folkman","year":"1988","journal-title":"J. Pers. Soc. Psychol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1088\/0967-3334\/22\/4\/305","article-title":"A method to standardize a reference of scalp EEG recordings to a point at infinity","volume":"22","author":"Yao","year":"2001","journal-title":"Physiol. Meas."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"601","DOI":"10.3389\/fnins.2017.00601","article-title":"MATLAB toolboxes for reference electrode standardization technique (REST) of scalp EEG","volume":"11","author":"Dong","year":"2017","journal-title":"Front. Neurosci."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1109\/TAU.1967.1161901","article-title":"The Use of Fast Fourier Transform for the Estimation of Power Spectra: A Method Based on Time Averaging Over Short, Modified Periodograms","volume":"15","author":"Welch","year":"1967","journal-title":"IEEE Trans. Audio Electroacoust."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"22","DOI":"10.5455\/njppp.2016.6.0616008072016","article-title":"The effect of slow and fast musical tempo on post-exercise recovery on recovery period in young adults","volume":"7","author":"Rane","year":"2017","journal-title":"Natl. J. Physiol. Pharm. Pharmacol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/nyas.12620","article-title":"Functional MRI of music emotion processing in frontotemporal dementia","volume":"1337","author":"Agustus","year":"2015","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1093\/brain\/awp345","article-title":"The cognitive organization of music knowledge: A clinical analysis","volume":"133","author":"Omar","year":"2010","journal-title":"Brain"},{"key":"ref_55","first-page":"1843","article-title":"The Anterior Portion of the Bilateral Temporal Lobes Participates in Music Perception: A Positron Emission Tomography Study","volume":"24","author":"Satoh","year":"2003","journal-title":"Am. J. Neuroradiol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.neuroimage.2013.02.024","article-title":"Pathways to seeing music: Enhanced structural connectivity in colored-music synesthesia","volume":"74","author":"Zamm","year":"2013","journal-title":"Neuroimage"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1093\/cercor\/bht036","article-title":"Anxiety and performance: The disparate roles of prefrontal subregions under maintained psychological stress","volume":"24","author":"Takizawa","year":"2014","journal-title":"Cereb. Cortex"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.neuron.2010.12.034","article-title":"Fear-Conditioning Mechanisms Associated with Trait Vulnerability to Anxiety in Humans","volume":"69","author":"Indovina","year":"2011","journal-title":"Neuron"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/nn1366","article-title":"Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter","volume":"8","author":"Heinz","year":"2005","journal-title":"Nat. Neurosci."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-017-02416-0","article-title":"Network connectivity determines cortical thinning in early Parkinson\u2019s disease progression","volume":"9","author":"Yau","year":"2018","journal-title":"Nat. Commun."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1159\/000286961","article-title":"Hostility may explain the association between depressive mood and mortality: Evidence from the french gazel cohort study","volume":"79","author":"Lemogne","year":"2010","journal-title":"Psychother. Psychosom."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"4723","DOI":"10.1182\/blood-2011-04-348730","article-title":"Adverse psychological outcomes in long-term survivors of hematopoietic cell transplantation: A report from the bone marrow transplant survivor study (BMTSS)","volume":"118","author":"Sun","year":"2011","journal-title":"Blood"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e12231","DOI":"10.2196\/12231","article-title":"Designing a chatbot for a brief motivational interview on stress management: Qualitative case study","volume":"21","author":"Park","year":"2019","journal-title":"J. Med. Internet Res."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncomms7026","article-title":"A number-form area in the blind","volume":"6","author":"Abboud","year":"2015","journal-title":"Nat. Commun."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/S1053-8119(03)00401-4","article-title":"Cortical neurophysiology of anticipatory anxiety: An investigation utilizing steady state probe topography (SSPT)","volume":"20","author":"Gray","year":"2003","journal-title":"Neuroimage"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"eaaw4358","DOI":"10.1126\/sciadv.aaw4358","article-title":"Emotion schemas are embedded in the human visual system","volume":"5","author":"Kragel","year":"2019","journal-title":"Sci. Adv."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"e2013097118","DOI":"10.1073\/pnas.2013097118","article-title":"A synthesis of health benefits of natural sounds and their distribution in national parks","volume":"118","author":"Buxton","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1093\/cercor\/bhl041","article-title":"Emotion induction after direct intracerebral stimulations of human amygdala","volume":"17","author":"Lanteaume","year":"2007","journal-title":"Cereb. Cortex"},{"key":"ref_69","unstructured":"Murray, E.A., Izquierdo, A., and Malkova, L. (2009). Amygdala Function in Positive Reinforcement: Contributions from Studies of Nonhuman Primates, The Guilford Press."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1037\/0021-843X.106.3.376","article-title":"Patterns of regional brain activity differentiate types of anxiety","volume":"106","author":"Heller","year":"1997","journal-title":"J. Abnorm. Psychol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/s41593-017-0051-7","article-title":"Generalizable representations of pain, cognitive control, and negative emotion in medial frontal cortex","volume":"21","author":"Kragel","year":"2018","journal-title":"Nat. Neurosci."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.tins.2012.04.012","article-title":"Functional network dysfunction in anxiety and anxiety disorders","volume":"35","author":"Sylvester","year":"2012","journal-title":"Trends Neurosci."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"3665","DOI":"10.1016\/j.neuropsychologia.2010.07.022","article-title":"Association between amygdala response to emotional faces and social anxiety in autism spectrum disorders","volume":"48","author":"Kleinhans","year":"2010","journal-title":"Neuropsychologia"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"e52984","DOI":"10.7554\/eLife.52984","article-title":"Push-pull competition between bottom-up and top-down auditory attention to natural soundscapes","volume":"9","author":"Huang","year":"2020","journal-title":"Elife"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.biopsych.2013.10.006","article-title":"Amygdala subregional structure and intrinsic functional connectivity predicts individual differences in anxiety during early childhood","volume":"75","author":"Qin","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1126\/science.1179210","article-title":"Right hemisphere lateralization for emotion in the human brain: Interactions with cognition","volume":"190","author":"Schwartz","year":"1975","journal-title":"Science"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0926-6410(03)00059-4","article-title":"Left-lateralized fMRI activation in the temporal lobe of high repressive women during the identification of sad prosodies","volume":"16","author":"Sander","year":"2003","journal-title":"Cogn. Brain Res."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3389\/fnhum.2013.00160","article-title":"The role of automaticity and attention in neural processes underlying empathy for happiness, sadness, and anxiety","volume":"7","author":"Morelli","year":"2013","journal-title":"Front. Hum. Neurosci."}],"container-title":["Brain Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3425\/11\/10\/1332\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:10:49Z","timestamp":1760166649000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3425\/11\/10\/1332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,9]]},"references-count":78,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2021,10]]}},"alternative-id":["brainsci11101332"],"URL":"https:\/\/doi.org\/10.3390\/brainsci11101332","relation":{},"ISSN":["2076-3425"],"issn-type":[{"value":"2076-3425","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,9]]}}}