{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T16:01:11Z","timestamp":1785600071338,"version":"3.56.0"},"reference-count":20,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T00:00:00Z","timestamp":1635379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Patients with severe hemiplegia along with knee instability require knee\u2013ankle\u2013foot orthoses (KAFOs) for gait training. However, in these patients, it is unclear which type of walking training is more effective to improve gait function. Providing alternate gait training (AGT) improves walking function in patients with spinal cord injury, but it is still unclear whether this is effective in hemiplegic stroke patients. In this study, we defined \u201cunified AGT\u201d as AGT performed with the same therapeutic concept by physiotherapists. We then investigated whether AGT improved gait function quicker than our traditional gait training in hemiplegic stroke patients. We enrolled 15 subjects with severe hemiplegia and knee instability who had undergone unified AGT using KAFOs with hinged oil dampers at the ankles, and 30 historical control (HC) subjects who had undergone traditional gait training. We used multiple comparison and survival analyses to analyze the differences in the functional independence measure (FIM) gait score changes between the two groups. The multiple comparison revealed a significant increase (p &lt; 0.05) in the FIM gait score compared with its initial score in the subjects with unified AGT. However, this improvement was not seen in the HC subjects. Additionally, the survival analysis of time taken to recover revealed a significant difference between the subjects with unified AGT and HC subjects (p &lt; 0.05). These findings suggest that unified AGT using a KAFO facilitates gait improvement in patients with severe hemiplegia and knee instability.<\/jats:p>","DOI":"10.3390\/brainsci11111430","type":"journal-article","created":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T23:50:28Z","timestamp":1635465028000},"page":"1430","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Impact of Alternate Gait Training Using Knee\u2013Ankle\u2013Foot Orthoses with Oil Damper Ankle Hinge in Patients with Subacute Severe Hemiplegia"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3632-3165","authenticated-orcid":false,"given":"Hiroaki","family":"Abe","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Fukushima Medical University School of Health Sciences, 10-6, Sakaemachi, Fukushima 960-8516, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazutaka","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Kita-Fukushima Medical Center, 23-1 Aza-higashi, Hakozaki, Date, Fukushima 960-0502, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Kita-Fukushima Medical Center, 23-1 Aza-higashi, Hakozaki, Date, Fukushima 960-0502, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Okanuka","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Kohnan Hospital, 4-20-1, Nagamachi-Minami, Taihaku-ku, Sendai 982-8523, Miyagi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhito","family":"Yonezawa","sequence":"additional","affiliation":[{"name":"Pacific Supply Co, Ltd., 1-12-1, Goryou, Daito, Osaka 574-0064, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Pacific Supply Co, Ltd., 1-12-1, Goryou, Daito, Osaka 574-0064, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.humov.2014.11.008","article-title":"The relative contribution of ankle moment and trailing limb angle to propulsive force during gait","volume":"39","author":"Hsiao","year":"2015","journal-title":"Hum. 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