{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T07:32:29Z","timestamp":1768721549754,"version":"3.49.0"},"reference-count":44,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T00:00:00Z","timestamp":1640476800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>The COVID-19 pandemic causes increased mental stress and decreased mobility, which may affect people with Parkinson\u2019s disease (PD). The study aimed to investigate the secondary impact of the COVID-19 pandemic on the level of activity, quality of life (QoL) and PD-related symptoms. The respondents completed an online survey in Polish in the period from December, 2020 to June, 2021. The questionnaire was completed by 47 participants aged 43 to 90 years (mean 72.1 \u00b1 1.3 years). A total of 94% reported reduced contact with family and friends. Over 90% remained active during the pandemic. However, 55% of people with PD showed subjectively lower level of activity then before the pandemic. Moreover, 36% of the respondents felt afraid to visit a doctor and reported problems with access to medication. Subjective QoL reduction was reported by 80%, and 83% declared worsening of PD symptoms. The post pandemic deterioration of motor symptoms in people with PD did not affect their QoL. However, the deterioration of contacts and feelings of isolation had a significant impact on the decline in quality of life (p = 0.022 and p = 0.009, respectively) and the presence of anxiety (p = 0.035 and p = 0.007, respectively). These results may indicate than greater importance of social and mental factors than fitness and health-related factors in the QoL self-assessment of the people with PD.<\/jats:p>","DOI":"10.3390\/brainsci12010026","type":"journal-article","created":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T01:00:54Z","timestamp":1640566854000},"page":"26","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Secondary Impact of COVID-19 Pandemic on People with Parkinson\u2019s Disease\u2014Results of a Polish Online Survey"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1658-9038","authenticated-orcid":false,"given":"Karolina","family":"Krzyszto\u0144","sequence":"first","affiliation":[{"name":"Department of Neurology, Faculty of Medical Sciences, Medical University of Warsaw, 01-809 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beata","family":"Miela\u0144czuk-Lubecka","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medical Sciences, Medical University of Warsaw, 01-809 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakub","family":"Stolarski","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medical Sciences, Medical University of Warsaw, 01-809 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Pozna\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Population Health Monitoring and Analysis, National Institute of Public Health NIH\u2013National Research Institute, 00-791 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"K\u0119pczy\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medical Sciences, Medical University of Warsaw, 01-809 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agata","family":"Zdrowowicz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medical Sciences, Medical University of Warsaw, 01-809 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izabela","family":"Domitrz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medical Sciences, Medical University of Warsaw, 01-809 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Kochanowski","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medical Sciences, Medical University of Warsaw, 01-809 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1007\/s13760-021-01732-z","article-title":"Lockdown effects on Parkinson\u2019s disease during COVID-19 pandemic: A pilot study","volume":"121","author":"Falla","year":"2021","journal-title":"Acta Neurol. Belg."},{"key":"ref_2","first-page":"204","article-title":"What can Parkinson\u2019s disease teach us about COVID-19?","volume":"54","author":"Tipton","year":"2020","journal-title":"Neurol. Neurochir. Pol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.3233\/JPD-202156","article-title":"Novel Outreach Program and Practical Strategies for Patients with Parkinsonism in the COVID-19 Pandemic","volume":"10","author":"Sennott","year":"2020","journal-title":"J. Parkinson\u2019s Dis."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1212\/WNL.0000000000009508","article-title":"On being a neurologist in Italy at the time of the COVID-19 outbreak","volume":"94","author":"Bersano","year":"2020","journal-title":"Neurology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/mdc3.12965","article-title":"Management of Advanced Therapies in Parkinson\u2019s Disease Patients in Times of Humanitarian Crisis: The COVID-19 Experience","volume":"7","author":"Fasano","year":"2020","journal-title":"Mov. Disord. Clin. Pract."},{"key":"ref_6","first-page":"2374373521997224","article-title":"Response to Telemedicine Visits from Patients with Parkinsonism During the COVID-19 Pandemic on Postvisit Surveys","volume":"8","author":"Deeb","year":"2021","journal-title":"J. Patient Exp."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.3233\/JPD-202411","article-title":"Global Perspective on Telemedicine for Parkinson\u2019s Disease","volume":"11","author":"Shalash","year":"2021","journal-title":"J. Parkinsons Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"627999","DOI":"10.3389\/fneur.2021.627999","article-title":"Effectiveness of Telerehabilitation on Motor Impairments, Non-motor Symptoms and Compliance in Patients with Parkinson\u2019s Disease: A Systematic Review","volume":"12","author":"Vellata","year":"2021","journal-title":"Front. Neurol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/S1474-4422(19)30285-6","article-title":"Effectiveness of home-based and remotely supervised aerobic exercise in Parkinson\u2019s disease: A double-blind, randomised controlled trial","volume":"18","author":"Kessels","year":"2019","journal-title":"Lancet Neurol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1002\/mds.25903","article-title":"The past, present, and future of telemedicine for Parkinson\u2019s disease","volume":"29","author":"Achey","year":"2014","journal-title":"Mov. Disord."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1002\/mds.28067","article-title":"Impact of the COVID-19 Pandemic on Parkinson\u2019s Disease and Movement Disorders","volume":"35","author":"Papa","year":"2020","journal-title":"Mov. Disord."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"105","DOI":"10.14802\/jmd.20042","article-title":"COVID-19: An Early Review of Its Global Impact and Considerations for Parkinson\u2019s Disease Patient Care","volume":"13","author":"Bhidayasiri","year":"2020","journal-title":"J. Mov. Disord."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3233\/JPD-202038","article-title":"The Impact of the COVID-19 Pandemic on Parkinson\u2019s Disease: Hidden Sorrows and Emerging Opportunities","volume":"10","author":"Helmich","year":"2020","journal-title":"J. Parkinson\u2019s Dis."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/MRR.0000000000000460","article-title":"Impact of the COVID-19 pandemic on physical activity, anxiety, and depression in patients with Parkinson\u2019s disease","volume":"44","author":"Balci","year":"2021","journal-title":"Int. J. Rehabil. Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3233\/JPD-202463","article-title":"COVID-19 and Parkinson\u2019s Disease: What Do We Know So Far?","volume":"11","author":"Artusi","year":"2021","journal-title":"J. Parkinson\u2019s Dis."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.parkreldis.2021.04.019","article-title":"Parkinson\u2019s disease may worsen outcomes from coronavirus disease 2019 (COVID-19) pneumonia in hospitalized patients: A systematic review, meta-analysis, and meta-regression","volume":"87","author":"Putri","year":"2021","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1002\/mds.28261","article-title":"Impact of Coronavirus Disease 2019 Pandemic on Parkinson\u2019s Disease: A Cross-Sectional Survey of 568 Spanish Patients","volume":"35","author":"Oreiro","year":"2020","journal-title":"Mov. Disord."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.3233\/JPD-202249","article-title":"The Effect of the COVID-19 Pandemic on People with Parkinson\u2019s Disease","volume":"10","author":"Brown","year":"2020","journal-title":"J. Parkinson\u2019s Dis."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/intqhc\/mzg031","article-title":"Good practice in the conduct and reporting of survey research","volume":"15","author":"Kelley","year":"2003","journal-title":"Int. J. Qual. Health Care"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.2196\/jmir.6.3.e34","article-title":"Improving the quality of Web surveys: The Checklist for Reporting Results of Internet E-Surveys (CHERRIES)","volume":"6","author":"Eysenbach","year":"2004","journal-title":"J. Med. Internet Res."},{"key":"ref_21","first-page":"1216568","article-title":"Influence of the COVID-19 Pandemic on Quality of Life of Patients with Parkinson\u2019s Disease","volume":"2020","author":"Guo","year":"2020","journal-title":"Parkinson\u2019s Dis."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1002\/mds.28116","article-title":"Incidence of Anxiety in Parkinson\u2019s Disease During the Coronavirus Disease (COVID-19) Pandemic","volume":"35","author":"Salari","year":"2020","journal-title":"Mov. Disord."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41531-020-00128-9","article-title":"Synergy of pandemics-social isolation is associated with worsened Parkinson severity and quality of life","volume":"6","author":"Subramanian","year":"2020","journal-title":"npj Parkinson\u2019s Dis."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Luis-Mart\u00ednez, R., Di Marco, R., Weis, L., Cianci, V., Pistonesi, F., Baba, A., Carecchio, M., Biundo, R., Tedesco, C., and Masiero, S. (2021). Impact of social and mobility restrictions in Parkinson\u2019s disease during COVID-19 lockdown. BMC Neurol., 21.","DOI":"10.1186\/s12883-021-02364-9"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1002\/mds.28293","article-title":"The Impact of COVID-19 on Access to Parkinson\u2019s Disease Medication","volume":"35","author":"Cheong","year":"2020","journal-title":"Mov. Disord."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1007\/s10072-020-04442-1","article-title":"Self-reported needs of patients with Parkinson\u2019s disease during COVID-19 emergency in Italy","volume":"41","author":"Schirinzi","year":"2020","journal-title":"Neurol. Sci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1002\/mds.28088","article-title":"Parkinson\u2019s Disease and COVID-19: Perceptions and Implications in Patients and Caregivers","volume":"35","author":"Prasad","year":"2020","journal-title":"Mov. Disord."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1111\/ene.14912","article-title":"Factors associated with COVID-19 in people with Parkinson\u2019s disease: A systematic review and meta-analysis","volume":"28","author":"Custodio","year":"2021","journal-title":"Eur. J. Neurol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.parkreldis.2020.09.003","article-title":"Impact of home confinement during COVID-19 pandemic on Parkinson\u2019s disease","volume":"80","author":"Kumar","year":"2020","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1002\/mdc3.13026","article-title":"Physical Activity Changes and Correlate Effects in Patients with Parkinson\u2019s Disease during COVID-19 Lockdown","volume":"7","author":"Schirinzi","year":"2020","journal-title":"Mov. Disord. Clin. Pract."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1002\/mds.28134","article-title":"Mental Health, Physical Activity, and Quality of Life in Parkinson\u2019s Disease During COVID-19 Pandemic","volume":"35","author":"Shalash","year":"2020","journal-title":"Mov. Disord."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/s41531-020-00153-8","article-title":"The impact of COVID-19 and social distancing on people with Parkinson\u2019s disease: A survey study","volume":"7","author":"Feeney","year":"2021","journal-title":"npj Parkinson\u2019s Dis."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.parkreldis.2020.09.034","article-title":"The changes of exercise pattern and clinical symptoms in patients with Parkinson\u2019s disease in the era of COVID-19 pandemic","volume":"80","author":"Song","year":"2020","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1007\/s00415-020-10002-6","article-title":"Prevalence and impact of COVID-19 in Parkinson\u2019s disease: Evidence from a multi-center survey in Tuscany region","volume":"268","author":"Francesconi","year":"2021","journal-title":"J. Neurol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"217","DOI":"10.4103\/aian.AIAN_1240_20","article-title":"The impact of COVID-19 pandemic on disease severity and quality of life in Parkinson\u2019s disease","volume":"24","author":"Saluja","year":"2021","journal-title":"Ann. Indian Acad. Neurol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1002\/mds.28766","article-title":"Effects of the Coronavirus Disease 2019 Pandemic on Motor Symptoms in Parkinson\u2019s Disease: An Observational Study","volume":"36","author":"Kainaga","year":"2021","journal-title":"Mov. Disord."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"121","DOI":"10.4103\/aian.AIAN_97_21","article-title":"Impact of COVID-19 Pandemic on Parkinson\u2019s Disease: A Tale of Fears and Sorrows!","volume":"24","author":"Kumar","year":"2021","journal-title":"Ann. Indian Acad. Neurol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.parkreldis.2020.08.012","article-title":"Predictors of COVID-19 outcome in Parkinson\u2019s disease","volume":"78","author":"Fasano","year":"2020","journal-title":"Parkinsonism Relat. Disord."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.3233\/JAD-210319","article-title":"Dementia and Parkinson\u2019s Disease: Risk Factors for 30-Day Mortality in Nursing Home Residents with COVID-19","volume":"84","author":"Rutten","year":"2021","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Xu, Y., Surface, M., Chan, A.K., Halpern, J., Vanegas-Arroyave, N., Ford, B., Feeney, M.P., Kwei, K.T., Katus, L.E., and Kuo, S.H. (2021). COVID-19 manifestations in people with Parkinson\u2019s disease: A USA cohort. J. Neurol., 1\u20137. [published online ahead of print, 4 September 2021].","DOI":"10.1007\/s00415-021-10784-3"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Sorbera, C., Brigand\u00ec, A., Cimino, V., Bonanno, L., Ciurleo, R., Bramanti, P., Di Lorenzo, G., and Marino, S. (2021). The impact of SARS-COV2 infection on people in residential care with Parkinson Disease or parkinsonisms: Clinical case series study. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0251313"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1002\/mds.28176","article-title":"COVID-19 in Parkinson\u2019s Disease Patients Living in Lombardy, Italy","volume":"35","author":"Fasano","year":"2020","journal-title":"Mov. Disord."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Yu, Y., Travaglio, M., Popovic, R., Leal, N.S., and Martins, L.M. (2021). Alzheimer\u2019s and Parkinson\u2019s Diseases Predict Different COVID-19 Outcomes: A UK Biobank Study. Geriatrics, 6.","DOI":"10.3390\/geriatrics6010010"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s11910-018-0834-6","article-title":"The Promise of Telemedicine for Movement Disorders: An Interdisciplinary Approach","volume":"18","author":"Browne","year":"2018","journal-title":"Curr. Neurol. Neurosci. Rep."}],"container-title":["Brain Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3425\/12\/1\/26\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:53:44Z","timestamp":1760169224000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3425\/12\/1\/26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,26]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1]]}},"alternative-id":["brainsci12010026"],"URL":"https:\/\/doi.org\/10.3390\/brainsci12010026","relation":{},"ISSN":["2076-3425"],"issn-type":[{"value":"2076-3425","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,26]]}}}