{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:36:13Z","timestamp":1784122573208,"version":"3.55.0"},"reference-count":46,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T00:00:00Z","timestamp":1646611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Introduction: Computation estimation is the ability to provide an approximate answer to a complex arithmetic problem without calculating it exactly. Despite its importance in daily life, the neuronal network underlying computation estimation is largely unknown. Methods: We looked at the neuronal correlates of two computational estimation strategies: approximated calculation and sense of magnitude (SOM)\u2013intuitive representation of magnitude, without calculation. During an fMRI scan, thirty-one college students judged whether the result of a two-digit multiplication problem was larger or smaller than a given reference number. In two different blocks, they were asked to use a specific strategy (AC or SOM). Results: The two strategies activated brain regions related to calculation, numerical cognition, decision-making, and working memory. AC more than SOM elicited activations in multiple, domain-specific brain regions in the parietal lobule, including the left SMG (BA 40), the bilateral superior parietal lobule (BA 7), and the right inferior parietal lobule (BA 7). The activation level of the IFG was positively correlated to individual accuracy, indicating that the IFG has an essential role in both strategies. Conclusions: These finding suggest that the analogic code of magnitude is more involved in the AC than the SOM strategy.<\/jats:p>","DOI":"10.3390\/brainsci12030357","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T10:21:16Z","timestamp":1646648476000},"page":"357","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Neural Correlates of Numerical Estimation: The Role of Strategy Use"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4343-4824","authenticated-orcid":false,"given":"Sarit","family":"Ashkenazi","sequence":"first","affiliation":[{"name":"Learning Disabilities, The Seymour Fox School of Education, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Refael","family":"Tikochinski","sequence":"additional","affiliation":[{"name":"Technion, Israel Institute of Technology, Haifa 3200003, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Ganor-Stern","sequence":"additional","affiliation":[{"name":"Achva Academic College, Shikmim 7980400, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1162\/089892999563689","article-title":"Differential contributions of the left and right inferior parietal lobules to number processing","volume":"11","author":"Chochon","year":"1999","journal-title":"J. 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