{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:57:49Z","timestamp":1760237869215,"version":"build-2065373602"},"reference-count":13,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T00:00:00Z","timestamp":1653868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>We present a rare case of intracranial solitary plasmacytoma arising in brain parenchyma in the basal nuclei. Clinical management and autopsy results of the case are described. Background: Intracranial plasmacytomas arising from brain parenchyma are extremely rare, and data from the literature are limited. Primary intracranial plasmacytomas are rare because plasma cells are not found in the brain in normal conditions. Commonly, intracranial plasmacytoma is associated with multiple myeloma, which is why multiple myeloma must be ruled out to diagnose solitary intracranial plasmacytoma. Considering that solitary plasmacytoma and multiple myeloma have some histopathological similarities, it is important to differentiate them because their respective treatments and prognoses are different. Imaging features of primary extramedullary plasmacytoma are nonspecific but are compatible with solid tumors with invariable enhancement. Plasmacytoma was aggressive because it was not diagnosed after the first MRI, but 1.5 months later, MRI showed a large object. We present a rare case of intracranial solitary plasmacytoma arising in brain parenchyma in the basal nuclei.<\/jats:p>","DOI":"10.3390\/brainsci12060705","type":"journal-article","created":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T10:05:14Z","timestamp":1653905114000},"page":"705","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intracerebral Plasmacytoma in a Patient with HIV-1 Infection and SARS-CoV-2 Superinfection"],"prefix":"10.3390","volume":"12","author":[{"given":"Jurijs","family":"Nazarovs","sequence":"first","affiliation":[{"name":"Pathology Centre, Riga East Clinical University Hospital, Hipokr\u0101ta Street 2, LV-1038 R\u012bga, Latvia"},{"name":"Pathology Institute, Pauls Stradins Clinical University Hospital, Pilso\u0146u Street 13, LV-1002 R\u012bga, Latvia"},{"name":"Department of Pathology, Riga Stradins University, Dzirciema Street 16, LV-1007 R\u012bga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daira","family":"Lapse","sequence":"additional","affiliation":[{"name":"Pathology Centre, Riga East Clinical University Hospital, Hipokr\u0101ta Street 2, LV-1038 R\u012bga, Latvia"},{"name":"Pathology Institute, Pauls Stradins Clinical University Hospital, Pilso\u0146u Street 13, LV-1002 R\u012bga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunta","family":"St\u016bre","sequence":"additional","affiliation":[{"name":"Latvian Centre of Infectious Diseases, Riga East Clinical University Hospital, Linezera, LV-1002 R\u012bga, Latvia"},{"name":"Department of Infectious Diseases, Riga Stradins University, Dzirciema Street 16, LV-1007 R\u012bga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Solovei\u010dika","sequence":"additional","affiliation":[{"name":"Department of Laboratory, Riga East Clinical University Hospital, Hipokrata Street 2, LV-1038 R\u012bga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u012bga","family":"Jaunozolina","sequence":"additional","affiliation":[{"name":"Pathology Centre, Riga East Clinical University Hospital, Hipokr\u0101ta Street 2, LV-1038 R\u012bga, Latvia"},{"name":"Department of Radiology, Riga Stradins University, Dzirciema Street 16, LV-1007 R\u012bga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"El\u012bna","family":"Ozoli\u0146a","sequence":"additional","affiliation":[{"name":"Pathology Centre, Riga East Clinical University Hospital, Hipokr\u0101ta Street 2, LV-1038 R\u012bga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Lejniece","sequence":"additional","affiliation":[{"name":"Hematology and Chemotherapy Clinic, Riga East Clinical University Hospital, Hipokr\u0101ta Street 2, LV-1038 R\u012bga, Latvia"},{"name":"Department of Internal Diseases, Riga Stradins University, Dzirciema Street 16, LV-1007 R\u012bga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e350","DOI":"10.1200\/JCO.2012.43.0215","article-title":"Unusal case of solitary intraparenchymal brain plasmacytoma","volume":"30","author":"Ferrari","year":"2012","journal-title":"Am. Soc. Clin. Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"102","DOI":"10.4103\/1793-5482.143460","article-title":"Solitary dural plasmacytoma with parenchymal invasion","volume":"10","author":"Khalili","year":"2015","journal-title":"Asian J. Neurosurg."},{"key":"ref_3","unstructured":"Swerdlow, S.H., Campo, E., Harris, N.L., Jaffe, E.S., Pileri, S.A., Stein, H., and Thiele, J. (2017). WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, WHO Press. [4th ed.]."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/1746-1596-6-123","article-title":"Extraosseous (extramedullary) plasmacytomas: A clinicopathologic and immunophenotypic study of 32 Chinese cases","volume":"6","author":"Zuo","year":"2011","journal-title":"Diagn. 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Multiple Myeloma: A Quick Reflection on the Fast Progress, IntechOpen.","DOI":"10.5772\/56515"}],"container-title":["Brain Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3425\/12\/6\/705\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:21:58Z","timestamp":1760138518000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3425\/12\/6\/705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,30]]},"references-count":13,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,6]]}},"alternative-id":["brainsci12060705"],"URL":"https:\/\/doi.org\/10.3390\/brainsci12060705","relation":{},"ISSN":["2076-3425"],"issn-type":[{"type":"electronic","value":"2076-3425"}],"subject":[],"published":{"date-parts":[[2022,5,30]]}}}