{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:42:19Z","timestamp":1791830539328,"version":"4.3.4"},"reference-count":62,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970877"],"award-info":[{"award-number":["81970877"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["BK20200054"],"award-info":[{"award-number":["BK20200054"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["BE2019670"],"award-info":[{"award-number":["BE2019670"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Jiangsu Provincial Natural Science Foundation\u2014Outstanding Youth Foundation","award":["81970877"],"award-info":[{"award-number":["81970877"]}]},{"name":"Jiangsu Provincial Natural Science Foundation\u2014Outstanding Youth Foundation","award":["BK20200054"],"award-info":[{"award-number":["BK20200054"]}]},{"name":"Jiangsu Provincial Natural Science Foundation\u2014Outstanding Youth Foundation","award":["BE2019670"],"award-info":[{"award-number":["BE2019670"]}]},{"name":"Jiangsu Provincial Key Research and Development Program Special Funds","award":["81970877"],"award-info":[{"award-number":["81970877"]}]},{"name":"Jiangsu Provincial Key Research and Development Program Special Funds","award":["BK20200054"],"award-info":[{"award-number":["BK20200054"]}]},{"name":"Jiangsu Provincial Key Research and Development Program Special Funds","award":["BE2019670"],"award-info":[{"award-number":["BE2019670"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>The relative benefit of ipsilateral, contralateral, and bilateral repetitive transcranial magnetic stimulation (rTMS) for tinnitus treatment remains unclear, especially for patients with lateralized tinnitus. In this study, we compared outcomes after 10 sessions of 1-Hz rTMS at 110% of resting motor threshold over a two-week period. In total, 104 right-handed patients with lateralized subjective tinnitus were randomly divided into four groups according to rTMS treatment: Left (n = 29), Right (n = 23), Bilateral (n = 30), and Sham stimulation (n = 22). Outcomes included estimates of tinnitus severity, psychological state, and psychoacoustic measures. Patients with left- or right-sided tinnitus were similarly distributed across treatment groups. There were no significant changes in outcome measures for the Right or Sham treatment groups. For the Left and Bilateral groups, tinnitus severity was significantly lower after treatment (p &lt; 0.05). The reduction in tinnitus severity was largest for ipsilateral treatment in the Left group. The overall response rate was 56.1% for the Left group, 46.7% for the Bilateral group, 8.3% for the Right group, and 8.3% for the Sham group. For the Left and Bilateral groups, the response rate was larger for patients with left- than right-sided tinnitus. Changes in tinnitus severity were best predicted by changes in anxiety, depression, and the loudness of the tinnitus. The results suggests that rTMS on the left temporoparietal cortex is more effective for patients with left-sided than with right-sided tinnitus.<\/jats:p>","DOI":"10.3390\/brainsci12060733","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T11:05:02Z","timestamp":1654167902000},"page":"733","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Effect of Ipsilateral, Contralateral or Bilateral Repetitive Transcranial Magnetic Stimulation in Patients with Lateralized Tinnitus: A Placebo-Controlled Randomized Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Yi","family":"Li","sequence":"first","affiliation":[{"name":"Department of Ear, Nose, and Throat, Dushu Lake Hospital Affiliated of Soochow University, Suzhou 215000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Cong","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Ear, Nose, and Throat, The First Affiliated of Soochow University, Suzhou 215000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"John J.","family":"Galvin","sequence":"additional","affiliation":[{"name":"House Institute Foundation, Los Angeles, CA 90057, USA"},{"name":"University Hospital Center of Tours, 37000 Tours, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Sheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ear, Nose, and Throat, The First Affiliated of Soochow University, Suzhou 215000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duo-Duo","family":"Tao","sequence":"additional","affiliation":[{"name":"Department of Ear, Nose, and Throat, Shaanxi Provincial People\u2019s Hospital, Xi\u2019an 710068, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.3109\/15622975.2011.575178","article-title":"Tinnitus and depression","volume":"12","author":"Langguth","year":"2011","journal-title":"World J. Biol. Psychiatry"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/S1474-4422(13)70160-1","article-title":"Tinnitus: Causes and clinical management","volume":"12","author":"Langguth","year":"2013","journal-title":"Lancet Neurol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.drudis.2009.11.003","article-title":"Pharmacological approaches to the treatment of tinnitus","volume":"15","author":"Elgoyhen","year":"2010","journal-title":"Drug Discov. Today"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1016\/S0140-6736(12)60469-3","article-title":"Specialised treatment based on cognitive behaviour therapy versus usual care for tinnitus: A randomised controlled trial","volume":"379","author":"Cima","year":"2012","journal-title":"Lancet"},{"key":"ref_5","first-page":"CD006371","article-title":"Sound therapy (masking) in the management of tinnitus in adults","volume":"8","author":"Hobson","year":"2010","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1002\/lary.21825","article-title":"Systematic review and meta-analyses of randomized controlled trials examining tinnitus management","volume":"121","author":"Hoare","year":"2011","journal-title":"Laryngoscope"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/MAO.0b013e31827b4d46","article-title":"Repetitive transcranial magnetic stimulation as a treatment for chronic tinnitus: A critical review","volume":"34","author":"Theodoroff","year":"2013","journal-title":"Otol. Neurotol."},{"key":"ref_8","first-page":"238","article-title":"Efficacy of repetitive transcranial magnetic stimulation for the treatment of refractory chronic tinnitus: A randomized, placebo controlled study","volume":"31","author":"Anders","year":"2010","journal-title":"Neuroendocrinol. Lett."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.brs.2013.01.015","article-title":"The effect of rTMS on auditory processing in adults with chronic, bilateral tinnitus: A placebo-controlled pilot study","volume":"6","author":"Barwood","year":"2013","journal-title":"Brain Stimul."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1001\/jamaoto.2015.1219","article-title":"Repetitive transcranial magnetic stimulation treatment for chronic tinnitus: A randomized clinical trial","volume":"141","author":"Folmer","year":"2015","journal-title":"JAMA Otolaryngol. Head. Neck Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.clinph.2019.11.002","article-title":"Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014\u20132018)","volume":"131","author":"Lefaucheur","year":"2020","journal-title":"Clin. Neurophysiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/j.1468-1331.2009.02730.x","article-title":"Repetitive transcranial magnetic stimulation improve tinnitus in normal hearing patients: A double-blind controlled, clinical and neuroimaging outcome study","volume":"17","author":"Marcondes","year":"2010","journal-title":"Eur. J. Neurol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1111\/j.1468-1331.2010.02956.x","article-title":"Left temporal low-frequency rTMS for the treatment of tinnitus: Clinical predictors of treatment outcome\u2014a retrospective study","volume":"17","author":"Frank","year":"2010","journal-title":"Eur. J. Neurol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1111\/j.1468-1331.2010.02965.x","article-title":"Contralateral versus ipsilateral rTMS of temporoparietal cortex for the treatment of chronic unilateral tinnitus: Comparative study","volume":"17","author":"Khedr","year":"2010","journal-title":"Eur. J. Neurol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3109\/15368378.2013.801353","article-title":"Comparison of the outcomes of repetitive transcranial magnetic stimulation to the ipsilateral and contralateral auditory cortex in unilateral tinnitus","volume":"33","author":"Kim","year":"2014","journal-title":"Electromagn. Biol. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1136\/jnnp.2006.105007","article-title":"Effects of repetitive transcranial magnetic stimulation on chronic tinnitus: A randomised, crossover, double blind, placebo controlled study","volume":"78","author":"Rossi","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1007\/s00405-015-3642-5","article-title":"Therapeutic impact of repetitive transcranial magnetic stimulation (rTMS) on tinnitus: A systematic review and meta-analysis","volume":"273","author":"Soleimani","year":"2016","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1159\/000354977","article-title":"Bilateral low-frequency repetitive transcranial magnetic stimulation of the auditory cortex in tinnitus patients is not effective: A randomised controlled trial","volume":"18","author":"Hoekstra","year":"2013","journal-title":"Audiol. Neurootol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/j.brs.2017.08.001","article-title":"1-Hz rTMS in the treatment of tinnitus: A sham-controlled, randomized multicenter trial","volume":"10","author":"Landgrebe","year":"2017","journal-title":"Brain Stimul."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1080\/14992027.2017.1313461","article-title":"Electric field-navigated transcranial magnetic stimulation for chronic tinnitus: A randomized, placebo-controlled study","volume":"56","author":"Sahlsten","year":"2017","journal-title":"Int. J. Audiol."},{"key":"ref_21","first-page":"268","article-title":"The distribution of left and right handedness in Chinese people","volume":"3","author":"Li","year":"1983","journal-title":"Acta Psychol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.endeavour.2012.12.003","article-title":"Why are there (almost) no left-handers in China?","volume":"37","author":"Kushner","year":"2012","journal-title":"Endeavour"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S1808-8694(15)30835-1","article-title":"Correlation analysis of the visual-analogue scale and the Tinnitus Handicap Inventory in tinnitus patients","volume":"75","author":"Figueiredo","year":"2009","journal-title":"Braz. J. Otorhinolaringol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.brs.2012.07.002","article-title":"Frontal cortex TMS for tinnitus","volume":"6","author":"Song","year":"2013","journal-title":"Brain Stimul."},{"key":"ref_25","first-page":"143","article-title":"Development of the tinnitus handicap inventory. Arch. Otolaryngol","volume":"122","author":"Newman","year":"1996","journal-title":"Head Neck Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1046\/j.1365-2273.2001.00490.x","article-title":"Guidelines for the grading of tinnitus severity: The results of a working group commissioned by the British Association of Otolaryngologists, Head and Neck Surgeons, 1999","volume":"26","author":"McCombe","year":"2001","journal-title":"Clin. Otolaryngol. Allied Sci."},{"key":"ref_27","first-page":"2331216518822198","article-title":"Neuronavigated versus non-navigated repetitive transcranial magnetic stimulation for chronic tinnitus: A randomized study","volume":"23","author":"Sahlsten","year":"2019","journal-title":"Trends Hear."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Yang, H., Cheng, G., Liang, Z., Deng, W., Huang, X., Gao, M., and Zheng, Y. (Ear Nose Throat J., 2021). Efficacy of repetitive transcranial magnetic stimulation (rTMS) for Tinnitus: A retrospective study, Ear Nose Throat J., Online ahead of print.","DOI":"10.1177\/01455613211016896"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr. Scand."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0013-4694(94)90029-9","article-title":"Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: Basic principles and procedures for routine clinical application. Report of an IFCN committee","volume":"91","author":"Rossini","year":"1994","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1080\/03655230600895317","article-title":"The impact of auditory cortex activity on characterizing and treating patients with chronic tinnitus\u2014First results from a PET study","volume":"556","author":"Langguth","year":"2006","journal-title":"Acta Otolaryngol. Suppl."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.heares.2012.02.010","article-title":"Gray matter in the brain: Differences associated with tinnitus and hearing loss","volume":"295","author":"Boyen","year":"2013","journal-title":"Hear Res."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/jnnp.2006.095612","article-title":"Moderate therapeutic efficacy of positron emission tomography-navigated repetitive transcranial magnetic stimulation for chronic tinnitus: A randomised, controlled pilot study","volume":"78","author":"Plewnia","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s00234-007-0231-3","article-title":"Lateralization of functional magnetic resonance imaging (fMRI) activation in the auditory pathway of patients with lateralized tinnitus","volume":"49","author":"Smits","year":"2007","journal-title":"Neuroradiology"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1097\/SCS.0000000000000782","article-title":"Effectiveness of transcranial magnetic stimulation application in treatment of tinnitus","volume":"25","author":"Yilmaz","year":"2014","journal-title":"J. Craniofac. Surg."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.anl.2015.09.004","article-title":"Combination of gaps in noise detection and visual analog scale for measuring tinnitus components in patients treated with repetitive transcranial magnetic stimulation","volume":"43","author":"Wang","year":"2016","journal-title":"Auris Nasus Larynx"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.heares.2017.10.017","article-title":"Glutamate is down- regulated and tinnitus loudness-levels decreased following rTMS over auditory cortex of the left hemisphere: A prospective randomized single-blinded sham-controlled cross-over study","volume":"358","author":"Cacace","year":"2018","journal-title":"Hear Res."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1001\/archoto.2011.3","article-title":"Low-frequency repetitive transcranial magnetic stimulation to the temporoparietal junction for tinnitus","volume":"137","author":"Piccirillo","year":"2011","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1212\/WNL.0b013e3182574ef9","article-title":"Treatment of chronic tinnitus with \u03b8 burst stimulation: A randomized controlled trial","volume":"78","author":"Plewnia","year":"2012","journal-title":"Neurology"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3109\/15622975.2012.708438","article-title":"Efficacy of different protocols of transcranial magnetic stimulation for the treatment of tinnitus: Pooled analysis of two randomized controlled studies","volume":"15","author":"Langguth","year":"2014","journal-title":"World J. Biol. Psychiatry"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1097\/01.mao.0000178146.91139.3c","article-title":"Transcranial magnetic stimulation for tinnitus: Influence of tinnitus duration on stimulation parameter choice and maximal tinnitus suppression","volume":"26","author":"Verstraeten","year":"2005","journal-title":"Otol. Neurotol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/0378-5955(94)90113-9","article-title":"Neurophysiological model of tinnitus: Dependence of the minimal masking level on treatment outcome","volume":"80","author":"Jastreboff","year":"1994","journal-title":"Hear Res."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"29","DOI":"10.5935\/0946-5448.20130005","article-title":"The relationship of perceived severity of tinnitus with depression, anxiety, hearing status, age and gender in individuals with tinnitus","volume":"18","author":"Udupi","year":"2013","journal-title":"Int. Tinnitus J."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1093\/cercor\/bhj070","article-title":"Structural brain changes in tinnitus","volume":"16","author":"Rauschecker","year":"2006","journal-title":"Cereb. Cortex"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1162\/jocn.2006.18.5.766","article-title":"Where and when the anterior cingulate cortex modulates attentional response: Combined fMRI and ERP evidence","volume":"18","author":"Menon","year":"2006","journal-title":"J. Cogn. Neurosci."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neubiorev.2019.04.008","article-title":"Prediction and perception: Insights for (and from) tinnitus","volume":"102","author":"Hullfish","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1037\/1040-3590.10.2.176","article-title":"Psychometric properties of the 42-item and 21-item versions of the Depression Anxiety Stress Scales in clinical groups and community a sample","volume":"10","author":"Antony","year":"1998","journal-title":"Psychol. Assess."},{"key":"ref_48","first-page":"97","article-title":"Determining the internal and external reliability of Depression, Anxiety and Stress Scales (DASS-21) in assessing psychological symptoms among patients with tinnitus","volume":"16","author":"Husain","year":"2018","journal-title":"NeuroQuantology"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"899","DOI":"10.3109\/14992027.2015.1054041","article-title":"Electric field navigated transcranial magnetic stimulation for chronic tinnitus: A pilot study","volume":"54","author":"Sahlsten","year":"2015","journal-title":"Int. J. Audiol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1177\/019459988409200617","article-title":"The perceived severity of tinnitus. Some observations concerning a large population of tinnitus clinic patients","volume":"92","author":"Meikle","year":"1984","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1067\/mhn.2001.114673","article-title":"Chronic tinnitus as phantom auditory pain. Otolaryngol","volume":"124","author":"Folmer","year":"2001","journal-title":"Head Neck Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1044\/1092-4388(2005\/084)","article-title":"General review of tinnitus: Prevalence, mechanisms, effects, and management","volume":"48","author":"Henry","year":"2005","journal-title":"J. Speech Lang. Hear Res."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/MAO.0000000000002070","article-title":"Relationship between tinnitus loudness measure by visual analogue scale and psychoacoustic matching of tinnitus loudness","volume":"40","author":"Gos","year":"2019","journal-title":"Otol. Neurotol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/108471389900400102","article-title":"Evaluation and selection of maskers and other devices used in the treatment of tinnitus and hyperacusis","volume":"4","author":"Sandlin","year":"1999","journal-title":"Trends Amplif."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1159\/000106482","article-title":"When tinnitus loudness and annoyance are discrepant: Audiological characteristics and psychological profile","volume":"12","author":"Hiller","year":"2007","journal-title":"Audiol. Neurootol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1017\/S1755146300090053","article-title":"Characteristics of tinnitus and related observations in over 1800 tinnitus clinic patients","volume":"9","author":"Meikle","year":"1984","journal-title":"J. Laryngol. Otol. Suppl."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1001\/archotol.132.12.1323","article-title":"Factors influencing tinnitus loudness and annoyance","volume":"132","author":"Hiller","year":"2006","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0194-5998(99)70123-3","article-title":"Tinnitus severity, loudness, and depression","volume":"121","author":"Folmer","year":"1999","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.heares.2012.03.010","article-title":"Laterality, frequency and replication of rTMS treatment for chronic tinnitus: Pilot studies and a review of maintenance treatment","volume":"295","author":"Mennemeier","year":"2013","journal-title":"Hear Res."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.neucli.2010.01.006","article-title":"Navigated transcranial magnetic stimulation","volume":"40","author":"Ruohonen","year":"2010","journal-title":"Neurophysiol. Clin."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.neuroimage.2008.09.040","article-title":"Comparison of navigated and non-navigated transcranial magnetic stimulation for motor cortex mapping, motor threshold and motor evoked potentials","volume":"44","author":"Julkunen","year":"2009","journal-title":"Neuroimage"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1080\/00016489.2017.1316870","article-title":"Comparison of treatment outcomes between 10 and 20 EEG electrode location system-guided and neuronavigation-guided repetitive transcranial magnetic stimulation in chronic tinnitus patients and target localization in the Asian brain","volume":"137","author":"Noh","year":"2010","journal-title":"Acta Oto-Laryngol."}],"container-title":["Brain Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3425\/12\/6\/733\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:24:02Z","timestamp":1760138642000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3425\/12\/6\/733"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,2]]},"references-count":62,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2022,6]]}},"alternative-id":["brainsci12060733"],"URL":"https:\/\/doi.org\/10.3390\/brainsci12060733","relation":{},"ISSN":["2076-3425"],"issn-type":[{"value":"2076-3425","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,2]]}}}