{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:20:02Z","timestamp":1792189202375,"version":"4.4.0"},"reference-count":40,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2022,6,18]],"date-time":"2022-06-18T00:00:00Z","timestamp":1655510400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Italian Ministry of Health","doi-asserted-by":"publisher","award":["Ricerca Corrente"],"award-info":[{"award-number":["Ricerca Corrente"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Brain asymmetry is connected with motor performance, suggesting that hemiparetic patients have different gait patterns depending on the side of the lesion. This retrospective cohort study aims to further investigate the difference between right and left hemiplegia in order to assess whether the injured side can influence the patient\u2019s clinical characteristics concerning gait, thus providing insights for new personalized rehabilitation strategies. The data from 33 stroke patients (17 with left and 16 with right hemiplegia) were retrospectively compared with each other and with a control group composed of 20 unaffected age-matched individuals. The 3D gait analysis was used to assess kinematic data and spatio-temporal parameters. Compared to left hemiplegic patients, right hemiplegic patients showed worse spatio-temporal parameters (p &lt; 0.05) and better kinematic parameters (p &lt; 0.05). Both pathological groups were characterized by abnormal gait parameters in comparison with the control group (p &lt; 0.05). These findings show an association between the side of the lesion\u2014right or left\u2014and the different stroke patients\u2019 gait patterns: left hemiplegic patients show better spatio-temporal parameters, whereas right hemiplegic patients show better segmentary motor performances. Therefore, further studies may develop and assess new personalized rehabilitation strategies considering the injured hemisphere and brain asymmetry.<\/jats:p>","DOI":"10.3390\/brainsci12060798","type":"journal-article","created":{"date-parts":[[2022,6,18]],"date-time":"2022-06-18T09:51:11Z","timestamp":1655545871000},"page":"798","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Brain Asymmetry and Its Effects on Gait Strategies in Hemiplegic Patients: New Rehabilitative Conceptions"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9034-7101","authenticated-orcid":false,"given":"Luca","family":"Vismara","sequence":"first","affiliation":[{"name":"Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano, 28824 Verbania, Italy"},{"name":"Department of Neurosciences \u201cRita Levi Montalcini\u201d, University of Turin, 10126 Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6299-7254","authenticated-orcid":false,"given":"Veronica","family":"Cimolin","sequence":"additional","affiliation":[{"name":"Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano, 28824 Verbania, Italy"},{"name":"Department of Electronics, Information and Bioengineering, Politecnico di Milano, 20133 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9363-9190","authenticated-orcid":false,"given":"Francesca","family":"Buffone","sequence":"additional","affiliation":[{"name":"Principles and Practice of Clinical Research (PPCR), Harvard T.H. Chan School of Public Health\u2013ECPE, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Bigoni","sequence":"additional","affiliation":[{"name":"Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano, 28824 Verbania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Clerici","sequence":"additional","affiliation":[{"name":"Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano, 28824 Verbania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1983-8204","authenticated-orcid":false,"given":"Serena","family":"Cerfoglio","sequence":"additional","affiliation":[{"name":"Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano, 28824 Verbania, Italy"},{"name":"Department of Electronics, Information and Bioengineering, Politecnico di Milano, 20133 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2772-4837","authenticated-orcid":false,"given":"Manuela","family":"Galli","sequence":"additional","affiliation":[{"name":"Department of Electronics, Information and Bioengineering, Politecnico di Milano, 20133 Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9072-7454","authenticated-orcid":false,"given":"Alessandro","family":"Mauro","sequence":"additional","affiliation":[{"name":"Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano, 28824 Verbania, Italy"},{"name":"Department of Neurosciences \u201cRita Levi Montalcini\u201d, University of Turin, 10126 Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,18]]},"reference":[{"key":"ref_1","unstructured":"GBD 2019 Diseases and Injuries Collaborators (2020). 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