{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T08:41:41Z","timestamp":1775378501987,"version":"3.50.1"},"reference-count":30,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T00:00:00Z","timestamp":1656547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Neurology of the Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n","award":["NER-0028-93-20-4"],"award-info":[{"award-number":["NER-0028-93-20-4"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background: Acute stroke care has greatly improved in recent decades. However, the increasing stroke mortality in low-to-middle income countries suggests that progress has not been reached completely by these populations. Here we present the analysis of the hospital phase of the first population-based stroke surveillance study. Methods: A daily hospital surveillance method was used to identify adult patients with acute stroke during 18 months in six hospitals. We abstracted data on demographics, vascular risk factors, neuroimaging-confirmed stroke types, and clinical data. Results: A total of 1361 adults with acute stroke were identified (mean age 69.2 years; 52% women) with transient ischemic attack (5.5%), acute ischemic stroke (68.6%), intracerebral hemorrhage (23.1%), cerebral venous thrombosis (0.2%), and undetermined stroke (2.6%). The main risk factors were hypertension (80.7%) and diabetes mellitus (47.6%). The usage rate of thrombolysis was 3.6%, in spite of the fact that 37.2% of acute ischemic stroke patients arrived in &lt;4.5 h. The 30-day case fatality rate was 32.6%, higher in hemorrhagic than ischemic stroke. Conclusion: We identified limitations in acute stroke care in the Mexico City, including neuroimaging availability and thrombolysis usage. The door-to-door phase will help to depict the acute stroke burden in Mexico.<\/jats:p>","DOI":"10.3390\/brainsci12070865","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T20:53:02Z","timestamp":1656622382000},"page":"865","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Acute Stroke Care in Mexico City: The Hospital Phase of a Stroke Surveillance Study"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2921-3096","authenticated-orcid":false,"given":"Emmanuel","family":"Aguilar-Salas","sequence":"first","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guadalupe","family":"Rodr\u00edguez-Aquino","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katya","family":"Garc\u00eda-Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalina","family":"Garfias-Guzm\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Hern\u00e1ndez-Camarillo","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3448-0789","authenticated-orcid":false,"given":"Nayeli","family":"Oropeza-Bustos","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rub\u00ed","family":"Arguelles-Castro","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ameyalli","family":"Mitre-Salazar","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Garc\u00eda-Torres","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital de Especialidades \u201cDr. Belisario Dom\u00ednguez\u201d, Mexico City 09930, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0774-8962","authenticated-orcid":false,"given":"Marco","family":"Reynoso-Marenco","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital General \u201cDr. Dar\u00edo Fern\u00e1ndez Fierro\u201d, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Mexico City 03900, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Morales-Andrade","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Hospital General \u201cDr. Dar\u00edo Fern\u00e1ndez Fierro\u201d, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Mexico City 03900, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Gervacio-Blanco","sequence":"additional","affiliation":[{"name":"Department of Emergencies, Hospital General \u201cDr. Dar\u00edo Fern\u00e1ndez Fierro\u201d, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Mexico City 03900, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edctor","family":"Garc\u00eda-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital General Tlahuac, Mexico City 13250, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Valiente-Herves","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital General de Zona 47, Instituto Mexicano del Seguro Social, Mexico City 09200, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0623-2008","authenticated-orcid":false,"given":"Manuel","family":"Mart\u00ednez-Marino","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital General de Zona 32, Instituto Mexicano del Seguro Social, Mexico City 04980, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Flores-Silva","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1142-295X","authenticated-orcid":false,"given":"Erwin","family":"Chiquete","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Cant\u00fa-Brito","sequence":"additional","affiliation":[{"name":"Department of Neurology and Psychiatry, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1161\/CIRCRESAHA.116.308413","article-title":"Global Burden of Stroke","volume":"120","author":"Feigin","year":"2017","journal-title":"Circ. Res."},{"key":"ref_2","first-page":"37","article-title":"Acute Stroke Registry Planning Experiences","volume":"45","author":"Shahraki","year":"2018","journal-title":"J. Regist. Manag."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1177\/1747493015607523","article-title":"National stroke registries for monitoring and improving the quality of hospital care: A systematic review","volume":"11","author":"Cadilhac","year":"2016","journal-title":"Int. J. Stroke"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1161\/STROKEAHA.109.577726","article-title":"Hospitalized Stroke Surveillance in the Community of Durango, M\u00e9xico. The Brain Attack Surveillance in Durango Study","volume":"41","author":"Majersik","year":"2010","journal-title":"Stroke"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1161\/STROKEAHA.110.592592","article-title":"Door-to-Door Capture of Incident and Prevalent Stroke Cases in Durango, Mexico The Brain Attack Surveillance in Durango Study","volume":"42","author":"Majersik","year":"2011","journal-title":"Stroke"},{"key":"ref_6","first-page":"224","article-title":"Factores de riesgo, causas y pron\u00f3stico de los tipos de enfermedad vascular cerebral en M\u00e9xico: Estudio RENAMEVASC","volume":"12","author":"Chiquete","year":"2011","journal-title":"Rev. Mex. Neurocienc."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.09.008","article-title":"Implementation of a Stroke Registry Is Associated with an Improvement in Stroke Performance Measures in a Tertiary Hospital in Mexico","volume":"24","author":"Herrera","year":"2015","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1016\/j.jstrokecerebrovasdis.2019.04.002","article-title":"Survival After Ischemic and Hemorrhagic Stroke: A 4-Year Follow-Up at a Mexican Hospital","volume":"28","year":"2019","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_9","first-page":"641","article-title":"Manejo agudo y pron\u00f3stico a un a\u00f1o en pacientes mexicanos con un primer infarto cerebral: Resultados del estudio multic\u00e9ntrico PREMIER","volume":"51","author":"Chiquete","year":"2010","journal-title":"Rev. Neurol."},{"key":"ref_10","unstructured":"Stepwise Approach to Surveillance (Steps) (2020, June 23). World Health Organization. Available online: http:\/\/www.WHO.Int\/chp\/steps\/en\/."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1161\/STR.0b013e318296aeca","article-title":"An updated definition of stroke for the 21st century: A statement for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"44","author":"Sacco","year":"2013","journal-title":"Stroke"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1177\/2396987318808719","article-title":"Action Plan for Stroke in Europe 2018\u20132030","volume":"3","author":"Norrving","year":"2018","journal-title":"Eur. Stroke J."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Zhou, Y., Yan, S., Song, X., Gong, Y., Li, W., Wang, M., Yin, X., Hu, B., and Lu, Z. (2019). Intravenous thrombolytic therapy for acute ischemic stroke in Hubei, China: A survey of thrombolysis rate and barriers. BMC Neurol., 19.","DOI":"10.1186\/s12883-019-1418-z"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.jstrokecerebrovasdis.2017.09.025","article-title":"Public and Private Hospital Care Disparities of Ischemic Stroke in Mexico: Results from the Primer Registro Mexicano de Isquemia Cerebral (PREMIER) Study","volume":"27","year":"2018","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_15","first-page":"200","article-title":"Hospital arrival time and functional outcome after acute ischaemic stroke: Results from the PREMIER study","volume":"29","author":"Chiquete","year":"2014","journal-title":"Neurolog\u00eda"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1007\/s10072-020-04929-x","article-title":"Prediction of acute neurovascular syndromes with prehospital clinical features witnessed by bystanders","volume":"42","author":"Chiquete","year":"2021","journal-title":"Neurol. Sci."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"917","DOI":"10.21149\/11095","article-title":"Encuesta Nacional de Salud y Nutrici\u00f3n (Ensanut 2018): Metodolog\u00eda y perspectivas [National Health and Nutrition Survey 2018\u201319: Methodology and perspectives]","volume":"61","year":"2019","journal-title":"Salud Publica Mex."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1161\/STROKEAHA.118.024695","article-title":"Stroke Incidence and Case Fatality According to Rural or Urban Residence. Results From the French Brest Stroke Registry","volume":"50","author":"Grimaud","year":"2019","journal-title":"Stroke"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1161\/STROKEAHA.117.019524","article-title":"Stroke Incidence and Outcomes in Northeastern Greece The Evros Stroke Registry","volume":"49","author":"Tsivgoulis","year":"2018","journal-title":"Stroke"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Radisaukas, R., Tamosiunas, A., Kranciukaite-Butylkiniene, D., Milinaviciene, E., Malinauskiene, V., Bernotiene, G., Luksiene, D., Virviciute, D., and Ratenyte, D. (2019). Long-term survival after stroke in Lituania: Data from Kaunas population-based stroke registry. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0219392"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1159\/000165364","article-title":"Population-Based Stroke Survey in Mumbai, India: Incidence and 28-Day Case Fatality","volume":"31","author":"Dalal","year":"2008","journal-title":"Neuroepidemiology"},{"key":"ref_22","first-page":"181","article-title":"Incidence and impact of stroke during Hajj","volume":"22","author":"Almekhlafi","year":"2017","journal-title":"Neurosci. J."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1253\/circj.CJ-17-0177","article-title":"Incidence, management and short-term outcome of stroke in a general population of 1.4 million Japanese","volume":"81","author":"Takashima","year":"2017","journal-title":"Circ. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/j.jstrokecerebrovasdis.2017.11.030","article-title":"Epidemiology of Stroke in Costa Rica: A 7-Year Hospital-Based Acute Stroke Registry of 1319 Consecutive Patients","volume":"27","author":"Chiou","year":"2018","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1016\/S0140-6736(05)66779-7","article-title":"Incidence, 30-day case-fatality rate, and prognosis of stroke in Iquique, Chile: A 2-year community-based prospective study (PISCIS project)","volume":"365","author":"Lavados","year":"2005","journal-title":"Lancet"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1136\/jnnp.2009.172098","article-title":"Incidence of stroke subtypes, prognosis and prevalence of risk factors in Joinville, Brazil: A 2 year community based study","volume":"80","author":"Cabral","year":"2009","journal-title":"J. Neurol. Neurosurg. Psychiatry Psychiatry"},{"key":"ref_27","first-page":"S11","article-title":"Epidemiology of smoking in Europe","volume":"44","author":"Fernandez","year":"2002","journal-title":"Salud Publica Mex."},{"key":"ref_28","unstructured":"Organizaci\u00f3n Panamericana de la Salud (2018). Informe Sobre el Control del Tabaco en la Regi\u00f3n de las Am\u00e9ricas, 2018, OPS."},{"key":"ref_29","first-page":"100204","article-title":"Trends in the burden of stroke in Mexico: A national and subnational analysis of the global burden of disease 1990\u20132019","volume":"10","author":"Chiquete","year":"2022","journal-title":"Lancet Reg. Health-Am."},{"key":"ref_30","first-page":"51","article-title":"Hospital Arrival and Functional Outcome after Intracerebral Hemorrhage","volume":"74","author":"Chiquete","year":"2022","journal-title":"Rev. Investig. Cl\u00ednica"}],"container-title":["Brain Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3425\/12\/7\/865\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:41:04Z","timestamp":1760139664000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3425\/12\/7\/865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,30]]},"references-count":30,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,7]]}},"alternative-id":["brainsci12070865"],"URL":"https:\/\/doi.org\/10.3390\/brainsci12070865","relation":{},"ISSN":["2076-3425"],"issn-type":[{"value":"2076-3425","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,30]]}}}