{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T21:27:46Z","timestamp":1783718866911,"version":"3.55.0"},"reference-count":49,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T00:00:00Z","timestamp":1658102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>According to previous studies, mental status in 1-year COVID-19 survivors might range from 6\u201343%. Longer-term psychological consequences in recovered COVID-19 subjects are unknown, so we analyzed longer-term quality of life and mental status in recovered COVID-19 subjects at 2 years after infection. Among 144 recovered COVID-19 subjects in the Taizhou region, 73 and 45 completed face-to-face follow-ups at the first year and second year after infection, respectively, with a 61.7% follow-up rate. The questionnaire, which was administered at both follow-ups, included questions about quality of life, psychological health, and post-traumatic stress disorder (PTSD). The Mann-Whitney U test was used to the differences of each scale between the first and second year. Among the 45 people who completed both follow-up visits, the incidence of psychological problems was 4.4% (2\/45) in the first year, and no new psychological abnormalities were observed in the second year. Quality of life improved, while the General Health Questionnaire (GHQ-12) and Impact of Event Scale-Revised (IES-R) scores did not improve over time. The incidence of mental disorders was lower than those in previous studies. Multidisciplinary management for COVID-19 in this study hospital may have reduced the frequency to a certain extent. However, among those with mental health problems, such problems may exist for a long time, and long-term attention should be given to the psychological status of recovered COVID-19 subjects.<\/jats:p>","DOI":"10.3390\/brainsci12070939","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T11:32:23Z","timestamp":1658143943000},"page":"939","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Quality of Life and Mental Health Status in Recovered COVID-19 Subjects at Two Years after Infection in Taizhou, China: A Longitudinal Cohort Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Juan","family":"Pan","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital, Zhejiang University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufen","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Die","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haixin","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuotao","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao-Hsin","family":"Tung","sequence":"additional","affiliation":[{"name":"Evidence-Based Medicine Center, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Taizhou Hospital, Zhejiang University, Linhai 317000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Cheng, V.C.-C., Ip, J.D., Chu, A.W.-H., Tam, A.R., Chan, W.-M., Abdullah, S.M.U., Chan, B.P.-C., Wong, S.-C., Kwan, M.Y.-W., and Chua, G.T. 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