{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:48:56Z","timestamp":1762300136569,"version":"build-2065373602"},"reference-count":26,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,8,7]],"date-time":"2022-08-07T00:00:00Z","timestamp":1659830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Kangdong Sacred Heart Hospital Fund","award":["2020-16"],"award-info":[{"award-number":["2020-16"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background and Purpose: Recent population-based studies from the US and UK have identified an increase in the occurrence of Guillain\u2013Barr\u00e9 syndrome (GBS) following coronavirus disease 2019 (COVID-19) vaccination. However, the localized variant of GBS might be underestimated due to its rarity and atypical features. We aimed to identify and characterize bilateral facial weakness with distal paresthesia (BFWdp) as a GBS variant following COVID-19 vaccination. Materials and Methods: Relevant studies published during the COVID-19 pandemic were searched and identified in the MEDLINE, Embase, and other databases. Results: This review found that 18 BFWdp cases presented characteristics similar to previous BFWdp cases as defined in the literature: male dominance, frequent albuminocytological dissociation, and acute inflammatory demyelinating neuropathy pattern. In contrast, facial nerve enhancement on brain MRI and antiganglioside antibody positivity were often observed in BFWdp following COVID-19 vaccination. Conclusions: The mechanism of BFWdp following COVID-19 vaccination appears to be somewhat different from that of sporadic BFWdp. Neurological syndromes with rare incidence and difficulty in diagnosis should be considered adverse events of COVID-19 vaccination.<\/jats:p>","DOI":"10.3390\/brainsci12081046","type":"journal-article","created":{"date-parts":[[2022,8,7]],"date-time":"2022-08-07T21:03:50Z","timestamp":1659906230000},"page":"1046","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Bilateral Facial Weakness with Distal Paresthesia Following COVID-19 Vaccination: A Scoping Review for an Atypical Variant of Guillain\u2013Barr\u00e9 Syndrome"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9532-5769","authenticated-orcid":false,"given":"Yoo-Hwan","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology, Hallym University Sacred Heart Hospital, Anyang 14068, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3811-3479","authenticated-orcid":false,"given":"Jee-Eun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Ewha Womans University College of Medicine, Seoul 03760, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byeol-A","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dong-A University College of Medicine, Busan 49201, Korea"},{"name":"Peripheral Neuropathy Research Center, Dong-A University College of Medicine, Busan 49201, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong-Kuk","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dong-A University College of Medicine, Busan 49201, Korea"},{"name":"Peripheral Neuropathy Research Center, Dong-A University College of Medicine, Busan 49201, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4313-1786","authenticated-orcid":false,"given":"Jong-Seok","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kangdong Sacred Heart Hospital, Seoul 05355, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1038\/s41591-021-01556-7","article-title":"Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection","volume":"27","author":"Patone","year":"2021","journal-title":"Nat. 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