{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:29:48Z","timestamp":1789140588751,"version":"build-2803163510"},"reference-count":43,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T00:00:00Z","timestamp":1661212800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Beijing\u2013Tianjin\u2013Hebei Project","award":["H2018206435"],"award-info":[{"award-number":["H2018206435"]}]},{"name":"Beijing\u2013Tianjin\u2013Hebei Project","award":["82101490"],"award-info":[{"award-number":["82101490"]}]},{"name":"National Natural Science Foundation of China","award":["H2018206435"],"award-info":[{"award-number":["H2018206435"]}]},{"name":"National Natural Science Foundation of China","award":["82101490"],"award-info":[{"award-number":["82101490"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Objective: Attachment and rumination were examined as the intermediary variables on post-traumatic stress disorder and medication compliance in stroke or TIA patients. Methods: A total of 300 participants with stroke or TIA from the Second Hospital of Hebei Province were selected. Patients accomplished NIHSS, ABCD2, ECR, RSQ, and RRS on admission. After 3 months, the PCL-C and MMAS were collected. Results: In the stroke or TIA patients, the incident of PTSD was 7.7%; PTSD scores were significantly associated with attachment anxiety (r = 0.225, p &lt; 0.01), symptom rumination (r = 0.197, p &lt; 0.01), and obsessive thinking (r = 0.187, p &lt; 0.01). After the Sobel test analysis and verification by the Baron and Kenny\u2019s stepwise approach we found that ruminant mediated the relationship between attachment anxiety and PTSD; obsessive thinking mediated the relationship between attachment anxiety and PTSD. Conclusions: The relationship between attachment anxiety and PTSD was positively predicted by rumination and obsessive thinking. Adult attachment style, rumination, and PTSD scores may not predict medication compliance.<\/jats:p>","DOI":"10.3390\/brainsci12091118","type":"journal-article","created":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T21:05:12Z","timestamp":1661288712000},"page":"1118","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Underlying Role of Rumination-Mediated Attachment Style Plays in PTSD after TIA and Stroke"],"prefix":"10.3390","volume":"12","author":[{"given":"Kaiping","family":"Zhou","sequence":"first","affiliation":[{"name":"Key Laboratory of Neurology of Hebei Province, Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang 050051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linjing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Peking University Third Hospital, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonggui","family":"Li","sequence":"additional","affiliation":[{"name":"School of Psychological and Cognitive Sciences, Peking University, Beijing 100191, China"},{"name":"Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6977-2653","authenticated-orcid":false,"given":"Weiping","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Neurology of Hebei Province, Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang 050051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1192\/bjpo.bp.115.001180","article-title":"The role of peri-traumatic stress and disruption distress in predicting post-traumatic stress disorder symptoms following exposure to a natural disaster","volume":"1","author":"Boden","year":"2015","journal-title":"BJPsych Open"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/jts.22129","article-title":"Posttraumatic Stress Disorder Symptoms, Intimate Partner Violence, and Relationship Functioning: A Meta-Analytic Review","volume":"29","author":"Birkley","year":"2016","journal-title":"J. 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