{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:18:05Z","timestamp":1791357485273,"version":"4.3.1"},"reference-count":21,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,24]],"date-time":"2022-12-24T00:00:00Z","timestamp":1671840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Narcolepsy type 1 (NT1), a central disorder of hypersomnolence, is associated with mood, anxiety or hyperactivity mental disorders. Association with psychotic episode or schizophrenia is rare and could be the source of diagnostic and therapeutic difficulties. Their frequency in the national narcolepsy database has not been systematically studied. The aim of the presented study was to calculate the frequency of NT1 patients diagnosed with psychosis and\/or schizophrenia, to identify clinical characteristics of these cases, and to look for narcoleptic and psychotic symptoms during re-evaluation years later. We identified three (4%) cases diagnosed with a psychotic episode in the course of NT1. They were diagnosed with NT1 by age \u226418 years. In the re-evaluation (mean follow-up 9.8 years), we identified one case with a dual diagnosis of NT1 and schizophrenia; two cases were diagnosed with a solitary psychotic episode in the course of NT1. NT1 patients diagnosed in the age \u226418 years are at higher risk of psychotic episode, and this may be related to higher vulnerability during the ongoing neurodevelopmental period. Comorbid schizophrenia with NT1 in the Slovakian Narcolepsy Database was within the prevalence expected in the general population. The solitary psychotic episode in the course of NT1 did not reduce the possibility of subsequent symptomatic treatment afterwards.<\/jats:p>","DOI":"10.3390\/brainsci13010043","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T04:45:54Z","timestamp":1672116354000},"page":"43","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Psychotic Episode and Schizophrenia in Slovakian Narcolepsy Database"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7746-3797","authenticated-orcid":false,"given":"Eva","family":"Feketeov\u00e1","sequence":"first","affiliation":[{"name":"Department of Neurology, Faculty of Medicine, University of P.J. \u0160af\u00e1rik and University Hospital of L. Pasteur, Trieda SNP 1, 04011 Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2938-6675","authenticated-orcid":false,"given":"Jozef","family":"Draga\u0161ek","sequence":"additional","affiliation":[{"name":"1st Department of Psychiatry, Faculty of Medicine, University of P.J. \u0160af\u00e1rik and University Hospital of L. Pasteur, Trieda SNP 1, 04011 Ko\u0161ice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katar\u00edna","family":"Klobu\u010dn\u00edkov\u00e1","sequence":"additional","affiliation":[{"name":"1st Department of Neurology, Faculty of Medicine, Comenius University and University Hospital in Bratislava, Mickiewiczova 13, 81369 Bratislava, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5813-3039","authenticated-orcid":false,"given":"Peter","family":"\u010eurd\u00edk","sequence":"additional","affiliation":[{"name":"Clinic of Children and Adolescents, Jessenius Faculty of Medicine, Comenius University in Bratislava and University Hospital in Martin, Kollarova 2, 03659 Martin, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"\u010carnakovi\u010d","sequence":"additional","affiliation":[{"name":"1st Department of Psychiatry, Faculty of Medicine, University of P.J. \u0160af\u00e1rik and University Hospital of L. 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