{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:27:44Z","timestamp":1791228464241,"version":"4.1.0"},"reference-count":40,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Chemsex is described as the use of certain drugs\u2014commonly methamphetamine, gamma-butyrolactone (GBL)\/gammahydroxybutyrate (GHB), and mephedrone\u2014before or during planned sexual activity primarily among men who have sex with men (MSM). Evidence shows that MSM who engage in chemsex are at increased risk of physical harm, such as sexually transmittable infections (STIs), and are more likely to experience mental health symptoms. To further assess this, we reviewed the recent literature to evaluate whether the psychological impact of chemsex behavior includes suicidal ideation and suicidal attempts. Pubmed\/MEDLINE was searched for articles reporting suicidal ideation and behavior among chemsex users with the terms \u201cchemsex\u201d, \u201csexualized drug use\u201d, \u201csuicide\u201d, and \u201cmental health\u201d. Twelve articles (three case reports and nine cross-sectional studies) were included in the final narrative review. Overall, we retrieved mixed results regarding the relationship between chemsex practice and suicidality outcomes. Considering the inhomogeneous nature of the studies, the findings indicate that suicidality could be an issue of concern among MSM in general but among chemsex users in particular. Possible risk factors for suicidality among chemsex participants may include adversities experienced due to one\u2019s sexual orientation and an increased risk for HIV and other STI infections and the resulting negative impact on mental well-being. These aspects warrant further investigations.<\/jats:p>","DOI":"10.3390\/brainsci13020174","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T02:35:55Z","timestamp":1674182155000},"page":"174","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Lethal Lust: Suicidal Behavior and Chemsex\u2014A Narrative Review of the Literature"],"prefix":"10.3390","volume":"13","author":[{"given":"Martina","family":"Strasser","sequence":"first","affiliation":[{"name":"Psychiatry and Psychotherapy, Faculty of Medicine, University of Augsburg, Geschwister-Sch\u00f6nert-Str. 1, 86156 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Halms","sequence":"additional","affiliation":[{"name":"Psychiatry and Psychotherapy, Faculty of Medicine, University of Augsburg, Geschwister-Sch\u00f6nert-Str. 1, 86156 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"R\u00fcther","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Ludwig-Maximilians-University Hospital Munich, 80336 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alkomiet","family":"Hasan","sequence":"additional","affiliation":[{"name":"Psychiatry and Psychotherapy, Faculty of Medicine, University of Augsburg, Geschwister-Sch\u00f6nert-Str. 1, 86156 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Gertzen","sequence":"additional","affiliation":[{"name":"Psychiatry and Psychotherapy, Faculty of Medicine, University of Augsburg, Geschwister-Sch\u00f6nert-Str. 1, 86156 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1136\/jfprhc-2016-101603","article-title":"A chemsex crucible: The context and the controversy","volume":"42","author":"Stuart","year":"2016","journal-title":"J. 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