{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T03:37:52Z","timestamp":1771990672468,"version":"3.50.1"},"reference-count":21,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background: Endoscopic third ventriculostomy (ETV) is an effective treatment for hydrocephalus. The in-depth understanding of microanatomy is essential for accurate diagnosis, treatment and complications prevention. The aim of this study is to supplement the knowledge gap regarding the microanatomical metrics and correlations for which the literature includes only scarce mentions at best. Methods: This is a descriptive microanatomical study including 25 cadaver brains. Specimens from donors with neurological, psychiatric disorders or alcohol abuse were excluded. Surgical loops were used for harvesting. High-precision tools were employed to dissect and measure the anatomical landmarks under a surgical microscope. Each measurement was performed in three consecutive attempts and outliers were rejected. RStudio was used for statistical analysis. Distribution was evaluated employing the Shapiro\u2013Wilk test. Normally distributed values were presented as mean and standard deviation, and others as median and interquartile range. Results: The age of the donors was 61.72 (\u00b110.08) years. The distance from the anterior aspect of the foramen of Monro to the anterior margin of the mamillary body was 16.83 (\u00b11.04) mm, and to the posterior margin was 16.76 (\u00b11.9) mm. The distance from the anterior mamillary body margin to the infundibulum was 6.39 (\u00b11.9) mm, to the optic recess was 8.25 (\u00b11.84) mm, and to the apex of the vertebral artery was 5.05 (\u00b11.62) mm. The distance from the anterior commissure to the brain aqueduct was 22.46 (\u00b12.29) mm, and to the infundibulum was 13.93 (\u00b12.54) mm. The mamillary body diameter was 4.91 (\u00b10.34) mm in the anteroposterior and 4.21 (\u00b10.48) mm in the cranio-caudal plane. The intraventricular segment was protruding by 1.63 (\u00b10.46) mm. The diameter of the hypothalamus on the anterior margin of mamillary bodies was 1.37 (\u00b10.75) mm, of the Liliequist membrane was 0.19 (\u00b10.07) mm and of the lamina terminalis was 0.35 (\u00b10.32) mm. Conclusion: The presented microanatomical measurements and correlations are expected to contribute to the improvement of ETV safety.<\/jats:p>","DOI":"10.3390\/brainsci13040580","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T02:23:46Z","timestamp":1680143026000},"page":"580","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Microanatomic Morphometric Characteristics of the Third Ventricle Floor"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6580-5382","authenticated-orcid":false,"given":"Marios","family":"Theologou","sequence":"first","affiliation":[{"name":"Second Department of Neurosurgery, General Hospital of Thessaloniki Hippokratio, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Kouskouras","sequence":"additional","affiliation":[{"name":"Department of Radiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Natsis","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Surgical Anatomy, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiotis","family":"Varoutis","sequence":"additional","affiliation":[{"name":"Second Department of Neurosurgery, General Hospital of Thessaloniki Hippokratio, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleni","family":"Zaggelidou","sequence":"additional","affiliation":[{"name":"Forensic Medical Service of Thessaloniki, Ministry of Justice, 54634 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christos","family":"Tsonidis","sequence":"additional","affiliation":[{"name":"Second Department of Neurosurgery, General Hospital of Thessaloniki Hippokratio, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.wneu.2019.04.255","article-title":"Endoscopic Third Ventriculostomy versus Ventriculoperitoneal Shunt in Patients with Obstructive Hydrocephalus: Meta-Analysis of Randomized Controlled Trials","volume":"129","author":"Lu","year":"2019","journal-title":"World Neurosurg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3171\/2010.11.PEDS10296","article-title":"Use of the ETV Success Score to explain the variation in reported endoscopic third ventriculostomy success rates among published case series of childhood hydrocephalus","volume":"7","author":"Kulkarni","year":"2011","journal-title":"J. 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