{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T11:44:23Z","timestamp":1771587863873,"version":"3.50.1"},"reference-count":49,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"SORNEST (Soci\u00e9t\u00e9 de R\u00e9adaptation du Nord-Est)","award":["Pierquin-Isch grant 2021"],"award-info":[{"award-number":["Pierquin-Isch grant 2021"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Unilateral spatial neglect (USN) rehabilitation requires the development of new methods that can be easily integrated into conventional practice. The aim of the HEMISTIM protocol is to assess immediate and long-term recovery induced by an innovative association of left-side neck-muscle vibration (NMV) and anodal transcranial Direct Current Stimulation (tDCS) on the ipsilesional posterior parietal cortex during occupational therapy sessions in patients with left USN. Participants will be randomly assigned to four groups: control, Left-NMV, Left-NMV + sham-tDCS or Left-NMV + anodal-tDCS. NMV and tDCS will be applied during the first 15 min of occupational therapy sessions, three days a week for three weeks. USN will be assessed at baseline, just at the end of the first experimental session, after the first and third weeks of the protocol and three weeks after its ending. Our primary outcome will be the evolution of the functional Catherine Bergego Scale score. Secondary outcome measures include five tests that investigate different neuropsychological aspects of USN. Left NMV, by activating multisensory integration neuronal networks, might enhance effects obtained by conventional therapy since post-effects were shown when it was combined with upper limb movements. We expect to reinforce lasting intermodal recalibration through LTP-like plasticity induced by anodal tDCS.<\/jats:p>","DOI":"10.3390\/brainsci13040678","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T01:39:05Z","timestamp":1681868345000},"page":"678","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Innovative Therapy Combining Neck Muscle Vibration and Transcranial Direct Current Stimulation in Association with Conventional Rehabilitation in Left Unilateral Spatial Neglect Patients: HEMISTIM Protocol for a Randomized Controlled Trial"],"prefix":"10.3390","volume":"13","author":[{"given":"Sarah","family":"Millot","sequence":"first","affiliation":[{"name":"UGECAM Nord-Est, Institut R\u00e9gional de M\u00e9decine Physique et de R\u00e9adaptation, Centre de M\u00e9decine Physique et de R\u00e9adaptation, Lay Saint-Christophe, France"},{"name":"Universit\u00e9 de Lorraine, DevAH, Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2213-4002","authenticated-orcid":false,"given":"Jean-Marie","family":"Beis","sequence":"additional","affiliation":[{"name":"UGECAM Nord-Est, Institut R\u00e9gional de M\u00e9decine Physique et de R\u00e9adaptation, Centre de M\u00e9decine Physique et de R\u00e9adaptation, Lay Saint-Christophe, France"},{"name":"Universit\u00e9 de Lorraine, DevAH, Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9650-434X","authenticated-orcid":false,"given":"Jonathan","family":"Pierret","sequence":"additional","affiliation":[{"name":"UGECAM Nord-Est, Institut R\u00e9gional de M\u00e9decine Physique et de R\u00e9adaptation, Centre de M\u00e9decine Physique et de R\u00e9adaptation, Lay Saint-Christophe, France"},{"name":"Universit\u00e9 de Lorraine, DevAH, Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Badin","sequence":"additional","affiliation":[{"name":"UGECAM Nord-Est, Institut R\u00e9gional de M\u00e9decine Physique et de R\u00e9adaptation, Centre de M\u00e9decine Physique et de R\u00e9adaptation, Lay Saint-Christophe, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verginia","family":"Sabau","sequence":"additional","affiliation":[{"name":"UGECAM PACA-Corse, Centre Helio Marin, Vallauris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Bensoussan","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, CNRS, INT, Marseille, France"},{"name":"UGECAM PACA, Institut Universitaire de R\u00e9adaptation de Valmante Sud, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Paysant","sequence":"additional","affiliation":[{"name":"UGECAM Nord-Est, Institut R\u00e9gional de M\u00e9decine Physique et de R\u00e9adaptation, Centre de M\u00e9decine Physique et de R\u00e9adaptation, Lay Saint-Christophe, France"},{"name":"Universit\u00e9 de Lorraine, DevAH, Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1746-5026","authenticated-orcid":false,"given":"Hadrien","family":"Ceyte","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, CNRS, ISM, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"101459","DOI":"10.1016\/j.rehab.2020.10.010","article-title":"Prevalence of spatial neglect post-stroke: A systematic review","volume":"64","author":"Esposito","year":"2021","journal-title":"Ann. 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