{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:06:00Z","timestamp":1760148360021,"version":"build-2065373602"},"reference-count":42,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>(1) Background: panic attack is often regarded as a benign disorder with variable physical and psychological symptoms. (2) Case Presentation: We here report the case of a 22-year-old patient known for an episode of motor functional neurological disorder a year earlier who presented a panic attack with hyperventilation causing severe hypophosphatemia and rhabdomyolysis, as well as mild tetraparesis. Electrolyte disturbances quickly resolved after phosphate substitution and rehydration. However, clinical signs suggesting a relapse of a motor functional neurological disorder appeared (improved walking with dual tasks). Diagnostic workup, including brain and spinal magnetic resonance imaging, as well as electroneuromyography and genetic testing for hypokalemic periodic paralysis, was unremarkable. Tetraparesis, lack of endurance, and fatigue eventually improved after several months. (3) Conclusions: the present case report highlights the intertwined relationship between a psychiatric disorder, leading to hyperventilation and acute metabolic disturbances, and functional neurological manifestations.<\/jats:p>","DOI":"10.3390\/brainsci13050726","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T02:50:00Z","timestamp":1682563800000},"page":"726","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Panic Attack, Severe Hypophosphatemia and Rhabdomyolysis in the Setting of a Motor Functional Neurological Disorder"],"prefix":"10.3390","volume":"13","author":[{"given":"Thibault","family":"Schneider","sequence":"first","affiliation":[{"name":"Division of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, 1206 Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2858-2439","authenticated-orcid":false,"given":"Nicolas","family":"Broc","sequence":"additional","affiliation":[{"name":"Division of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, 1206 Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatrice","family":"Leemann","sequence":"additional","affiliation":[{"name":"Division of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, 1206 Geneva, Switzerland"},{"name":"Faculty of Medicine, University of Geneva, 1206 Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Schnider","sequence":"additional","affiliation":[{"name":"Division of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, 1206 Geneva, Switzerland"},{"name":"Faculty of Medicine, University of Geneva, 1206 Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5836-0792","authenticated-orcid":false,"given":"Nicolas","family":"Nicastro","sequence":"additional","affiliation":[{"name":"Division of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, 1206 Geneva, Switzerland"},{"name":"Faculty of Medicine, University of Geneva, 1206 Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/jamaneurol.2018.1264","article-title":"Current concepts in diagnosis and treatment of functional neurological disorders","volume":"75","author":"Espay","year":"2018","journal-title":"JAMA Neurol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"100489","DOI":"10.1016\/j.ebr.2021.100489","article-title":"A historical review of functional neurological disorder and comparison to contemporary models","volume":"16","author":"Raynor","year":"2021","journal-title":"Epilepsy Behav."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013). 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