{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:15:06Z","timestamp":1760148906744,"version":"build-2065373602"},"reference-count":45,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T00:00:00Z","timestamp":1687132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Fapesp","doi-asserted-by":"publisher","award":["2017\/25046-4","301068\/2018-6","001"],"award-info":[{"award-number":["2017\/25046-4","301068\/2018-6","001"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","award":["2017\/25046-4","301068\/2018-6","001"],"award-info":[{"award-number":["2017\/25046-4","301068\/2018-6","001"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","award":["2017\/25046-4","301068\/2018-6","001"],"award-info":[{"award-number":["2017\/25046-4","301068\/2018-6","001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Recent studies involving guinea pigs have shown that noise can damage the synapses between the inner hair cells and spiral ganglion neurons, even with normal hearing thresholds\u2014which makes it important to investigate this kind of impairment in humans. The aim was to investigate, with multiple audiological assessments, the auditory function of normal hearing workers exposed to occupational noise. Altogether, 60 workers were assessed (30 in the noise-exposure group [NEG], who were exposed to occupational noise, and 30 in the control group [CG], who were not exposed to occupational noise); the workers were matched according to age. The following procedures were used: complete audiological assessment; speech recognition threshold in noise (SRTN); speech in noise (SN) in an acoustic field; gaps-in-noise (GIN); transient evoked otoacoustic emissions (TEOAE) and inhibitory effect of the efferent auditory pathway; auditory brainstem response (ABR); and long-latency auditory evoked potentials (LLAEP). No significant difference was found between the groups in SRTN. In SN, the NEG performed worse than the CG in signal-to-noise ratio (SNR) 0 (p-value 0.023). In GIN, the NEG had a significantly lower percentage of correct answers (p-value 0.042). In TEOAE, the NEG had smaller amplitude values bilaterally (RE p-value 0.048; LE p-value 0.045) and a smaller inhibitory effect of the efferent pathway (p-value 0.009). In ABR, the NEG had greater latencies of wave V (p-value 0.017) and interpeak intervals III-V and I-V in the LE (respective p-values: 0.005 and 0.04). In LLAEP, the NEG had a smaller P3 amplitude bilaterally (RE p-value 0.001; LE p-value 0.002). The NEG performed worse than the CG in most of the assessments, suggesting that the auditory function in individuals exposed to occupational noise is impaired, even with normal audiometric thresholds.<\/jats:p>","DOI":"10.3390\/brainsci13060968","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T02:26:56Z","timestamp":1687228016000},"page":"968","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of Subtle Auditory Impairments with Multiple Audiological Assessments in Normal Hearing Workers Exposed to Occupational Noise"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7164-8942","authenticated-orcid":false,"given":"Alessandra Giannella","family":"Samelli","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Speech-Language-Hearing Sciences, and Occupational Therapy, Medical School (FMUSP), University of S\u00e3o Paulo, S\u00e3o Paulo 05360-160, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9087-323X","authenticated-orcid":false,"given":"Clayton Henrique","family":"Rocha","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Speech-Language-Hearing Sciences, and Occupational Therapy, Medical School (FMUSP), University of S\u00e3o Paulo, S\u00e3o Paulo 05360-160, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Keiko","family":"Kamita","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Speech-Language-Hearing Sciences, and Occupational Therapy, Medical School (FMUSP), University of S\u00e3o Paulo, S\u00e3o Paulo 05360-160, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Elisa Pereira","family":"Lopes","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Speech-Language-Hearing Sciences, and Occupational Therapy, Medical School (FMUSP), University of S\u00e3o Paulo, S\u00e3o Paulo 05360-160, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila Quintiliano","family":"Andrade","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Speech-Language-Hearing Sciences, and Occupational Therapy, Medical School (FMUSP), University of S\u00e3o Paulo, S\u00e3o Paulo 05360-160, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla Gentile","family":"Matas","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Speech-Language-Hearing Sciences, and Occupational Therapy, Medical School (FMUSP), University of S\u00e3o Paulo, S\u00e3o Paulo 05360-160, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Moore, B.C.J. 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