{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:41:08Z","timestamp":1791528068188,"version":"4.3.4"},"reference-count":76,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T00:00:00Z","timestamp":1687132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>In everyday verbal communication, auditory speech perception is often disturbed by background noise. Especially in disadvantageous hearing conditions, additional visual articulatory information (e.g., lip movement) can positively contribute to speech comprehension. Patients with schizophrenia (SZs) demonstrate an aberrant ability to integrate visual and auditory sensory input during speech perception. Current findings about underlying neural mechanisms of this deficit are inconsistent. Particularly and despite the importance of early sensory processing in speech perception, very few studies have addressed these processes in SZs. Thus, in the present study, we examined 20 adult subjects with SZ and 21 healthy controls (HCs) while presenting audiovisual spoken words (disyllabic nouns) either superimposed by white noise (\u221212 dB signal-to-noise ratio) or not. In addition to behavioral data, event-related brain potentials (ERPs) were recorded. Our results demonstrate reduced speech comprehension for SZs compared to HCs under noisy conditions. Moreover, we found altered N1 amplitudes in SZ during speech perception, while P2 amplitudes and the N1-P2 complex were similar to HCs, indicating that there may be disturbances in multimodal speech perception at an early stage of processing, which may be due to deficits in auditory speech perception. Moreover, a positive relationship between fronto-central N1 amplitudes and the positive subscale of the Positive and Negative Syndrome Scale (PANSS) has been observed.<\/jats:p>","DOI":"10.3390\/brainsci13060970","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T02:26:56Z","timestamp":1687228016000},"page":"970","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Deficient Audiovisual Speech Perception in Schizophrenia: An ERP Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7585-9301","authenticated-orcid":false,"given":"Erfan","family":"Ghaneirad","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30635 Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellyn","family":"Saenger","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30635 Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor R.","family":"Szycik","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30635 Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"\u010cu\u0161","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30635 Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8339-8590","authenticated-orcid":false,"given":"Laura","family":"M\u00f6de","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30635 Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1716-6229","authenticated-orcid":false,"given":"Christopher","family":"Sinke","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30635 Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Wiswede","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of L\u00fcbeck, 23562 L\u00fcbeck, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Bleich","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30635 Hanover, Germany"},{"name":"Center for Systems Neuroscience, University of Veterinary Medicine, 30559 Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Borgolte","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30635 Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1001\/archpsyc.1991.01810270051007","article-title":"National Institute of Mental Health longitudinal study of chronic schizophrenia: Prognosis and predictors of outcome","volume":"48","author":"Breier","year":"1991","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1001\/archpsyc.1991.01810350018003","article-title":"Natural history of schizophrenia subtypes: II. Positive and negative symptoms and long-term course","volume":"48","author":"Fenton","year":"1991","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1162\/jocn.2007.19.12.1964","article-title":"Neural correlates of multisensory integration of ecologically valid audiovisual events","volume":"19","author":"Stekelenburg","year":"2007","journal-title":"J. Cogn. Neurosci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.schres.2004.01.010","article-title":"Brain activation patterns during a verbal fluency test\u2014A functional MRI study in healthy volunteers and patients with schizophrenia","volume":"70","author":"Weiss","year":"2004","journal-title":"Schizophr. Res."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/oxfordjournals.schbul.a033488","article-title":"Altered hemispheric functional dominance during word generation in negative schizophrenia","volume":"26","author":"Artiges","year":"2000","journal-title":"Schizophr. Bull."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.schres.2007.04.011","article-title":"Stability of functional language lateralization over time in schizophrenia patients","volume":"94","author":"Razafimandimby","year":"2007","journal-title":"Schizophr. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1038\/264746a0","article-title":"Hearing lips and seeing voices","volume":"264","author":"McGurk","year":"1976","journal-title":"Nature"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.neuropsychologia.2006.03.036","article-title":"Seeing voices: High-density electrical mapping and source-analysis of the multisensory mismatch negativity evoked during the McGurk illusion","volume":"45","author":"Molholm","year":"2007","journal-title":"Neuropsychologia"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1093\/cercor\/bhl024","article-title":"Do you see what I am saying? Exploring visual enhancement of speech comprehension in noisy environments","volume":"17","author":"Ross","year":"2007","journal-title":"Cereb. Cortex"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1121\/1.1288668","article-title":"The use of visible speech cues for improving auditory detection of spoken sentences","volume":"108","author":"Grant","year":"2000","journal-title":"J. Acoust. Soc. Am."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1121\/1.1907309","article-title":"Visual contribution to speech intelligibility in noise","volume":"26","author":"Sumby","year":"1954","journal-title":"J. Acoust. Soc. Am."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.neuron.2006.09.020","article-title":"Neural synchrony in brain disorders: Relevance for cognitive dysfunctions and pathophysiology","volume":"52","author":"Uhlhaas","year":"2006","journal-title":"Neuron"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.biopsych.2005.10.005","article-title":"Synaptic plasticity and dysconnection in schizophrenia","volume":"59","author":"Stephan","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"3128","DOI":"10.1016\/j.neuropsychologia.2010.06.028","article-title":"Reduced multisensory integration in patients with schizophrenia on a target detection task","volume":"48","author":"Williams","year":"2010","journal-title":"Neuropsychologia"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"100219","DOI":"10.1016\/j.scog.2021.100219","article-title":"A systematic review of the neural correlates of multisensory integration in schizophrenia","volume":"27","author":"Norgren","year":"2022","journal-title":"Schizophr. Res. Cogn."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"3178","DOI":"10.1016\/j.neuropsychologia.2011.07.017","article-title":"Unisensory processing and multisensory integration in schizophrenia: A high-density electrical mapping study","volume":"49","author":"Stone","year":"2011","journal-title":"Neuropsychologia"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.schres.2007.08.013","article-title":"Low time resolution in schizophrenia: Lengthened windows of simultaneity for visual, auditory and bimodal stimuli","volume":"97","author":"Foucher","year":"2007","journal-title":"Schizophr. Res."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.neuropsychologia.2012.07.002","article-title":"Temporal event structure and timing in schizophrenia: Preserved binding in a longer \u201cnow\u201d","volume":"51","author":"Martin","year":"2013","journal-title":"Neuropsychologia"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neubiorev.2017.12.013","article-title":"Multisensory temporal binding window in autism spectrum disorders and schizophrenia spectrum disorders: A systematic review and meta-analysis","volume":"86","author":"Zhou","year":"2018","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.3389\/fpsyg.2016.01896","article-title":"Beta\/gamma oscillations and event-related potentials indicate aberrant multisensory processing in schizophrenia","volume":"7","author":"Balz","year":"2016","journal-title":"Front. Psychol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0920-9964(01)00344-9","article-title":"Audio-visual integration in schizophrenia","volume":"59","author":"Vroomen","year":"2003","journal-title":"Schizophr. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.comppsych.2008.06.004","article-title":"Differences in audiovisual integration, as measured by McGurk phenomenon, among adult and adolescent patients with schizophrenia and age-matched healthy control groups","volume":"50","author":"Pearl","year":"2009","journal-title":"Compr. Psychiatry"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"565","DOI":"10.3389\/fnhum.2014.00565","article-title":"Eluding the illusion? Schizophrenia, dopamine and the McGurk effect","volume":"8","author":"White","year":"2014","journal-title":"Front. Hum. Neurosci."},{"key":"ref_24","first-page":"41","article-title":"Alpha-band oscillations reflect altered multisensory processing of the McGurk illusion in schizophrenia","volume":"10","author":"Keil","year":"2016","journal-title":"Front. Hum. Neurosci."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1002\/hbm.22015","article-title":"Neural integration of speech and gesture in schizophrenia: Evidence for differential processing of metaphoric gestures","volume":"34","author":"Straube","year":"2013","journal-title":"Hum. Brain Mapp."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.schres.2019.12.005","article-title":"Dynamic Causal Modelling suggests impaired effective connectivity in patients with schizophrenia spectrum disorders during gesture-speech integration","volume":"216","author":"Wroblewski","year":"2020","journal-title":"Schizophr. Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.neuroscience.2013.08.041","article-title":"Maladaptive connectivity of Broca\u2019s area in schizophrenia during audiovisual speech perception: An fMRI study","volume":"253","author":"Szycik","year":"2013","journal-title":"Neuroscience"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.schres.2009.03.003","article-title":"Audiovisual integration of speech is disturbed in schizophrenia: An fMRI study","volume":"110","author":"Szycik","year":"2009","journal-title":"Schizophr. Res."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1073\/pnas.0408949102","article-title":"Visual speech speeds up the neural processing of auditory speech","volume":"102","author":"Grant","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"14301","DOI":"10.1523\/JNEUROSCI.2875-08.2008","article-title":"Visual activation and audiovisual interactions in the auditory cortex during speech perception: Intracranial recordings in humans","volume":"28","author":"Besle","year":"2008","journal-title":"J. Neurosci."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1111\/j.1460-9568.2004.03670.x","article-title":"Bimodal speech: Early suppressive visual effects in human auditory cortex","volume":"20","author":"Besle","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.neuropsychologia.2013.11.011","article-title":"Electrophysiological evidence for speech-specific audiovisual integration","volume":"53","author":"Baart","year":"2014","journal-title":"Neuropsychologia"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.ijpsycho.2013.06.016","article-title":"Visual information constrains early and late stages of spoken-word recognition in sentence context","volume":"89","author":"Ikumi","year":"2013","journal-title":"Int. J. Psychophysiol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.schres.2013.04.038","article-title":"Deficient multisensory integration in schizophrenia: An event-related potential study","volume":"147","author":"Stekelenburg","year":"2013","journal-title":"Schizophr. Res."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"102909","DOI":"10.1016\/j.nicl.2021.102909","article-title":"Early evoked brain activity underlies auditory and audiovisual speech recognition deficits in schizophrenia","volume":"33","author":"Senkowski","year":"2022","journal-title":"NeuroImage Clin."},{"key":"ref_36","unstructured":"American Psychiatric Association (2000). Diagnostic and Statistical Manual of Mental Disorders (4th Ed text revision), American Psychiatric Association."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr. Bull."},{"key":"ref_38","unstructured":"Lehrl, S., Merz, J., Burkhard, G., and Fischer, S. (1999). Mehrfachwahl-Wortschatz-Intelligenztest, Straube. MWT-B."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.schres.2007.08.008","article-title":"Impaired multisensory processing in schizophrenia: Deficits in the visual enhancement of speech comprehension under noisy environmental conditions","volume":"97","author":"Ross","year":"2007","journal-title":"Schizophr. Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"108022","DOI":"10.1016\/j.neuropsychologia.2021.108022","article-title":"Enhanced attentional processing during speech perception in adult high-functioning autism spectrum disorder: An ERP-study","volume":"161","author":"Borgolte","year":"2021","journal-title":"Neuropsychologia"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3389\/fnhum.2014.00021","article-title":"N1 enhancement in synesthesia during visual and audio\u2013visual perception in semantic cross-modal conflict situations: An ERP study","volume":"8","author":"Sinke","year":"2014","journal-title":"Front. Hum. Neurosci."},{"key":"ref_42","unstructured":"Baayen, R.H., Piepenbrock, R., and Gulikers, L. (1995). The CELEX Lexical Database (CD-ROM), Linguistic Data Consortium, University of Pennsylvania."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.neuroscience.2013.05.007","article-title":"Correlation between audio\u2013visual enhancement of speech in different noise environments and SNR: A combined behavioral and electrophysiological study","volume":"247","author":"Liu","year":"2013","journal-title":"Neuroscience"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1111\/j.1469-8986.2011.01273.x","article-title":"Mass univariate analysis of event-related brain potentials\/fields I: A critical tutorial review","volume":"48","author":"Groppe","year":"2011","journal-title":"Psychophysiology"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/YCO.0000000000000595","article-title":"Anomalies in language as a biomarker for schizophrenia","volume":"33","author":"Brederoo","year":"2020","journal-title":"Curr. Opin. Psychiatry"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1176\/appi.ajp.158.7.1126","article-title":"Dysfunction of early-stage visual processing in schizophrenia","volume":"158","author":"Butler","year":"2001","journal-title":"Am. J. Psychiatry"},{"key":"ref_47","first-page":"317","article-title":"A review of impaired visual processing and the daily visual world in patients with schizophrenia","volume":"80","author":"Kogata","year":"2018","journal-title":"Nagoya J. Med. Sci."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"105098","DOI":"10.1016\/j.neubiorev.2023.105098","article-title":"Early auditory processing dysfunction in schizophrenia: Mechanisms and implications","volume":"148","author":"Kantrowitz","year":"2023","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1176\/ajp.156.3.393","article-title":"Selective speech perception alterations in schizophrenic patients reporting hallucinated \u201cvoices\u201d","volume":"156","author":"Hoffman","year":"1999","journal-title":"Am. J. Psychiatry"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0920-9964(97)00004-2","article-title":"Language processing and memory in ill and well siblings from multiplex families affected with schizophrenia","volume":"25","author":"Shedlack","year":"1997","journal-title":"Schizophr. Res."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.schres.2011.09.019","article-title":"Masking of speech in people with first-episode schizophrenia and people with chronic schizophrenia","volume":"134","author":"Wu","year":"2012","journal-title":"Schizophr. Res."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.0924-2708.2004.00071.x","article-title":"Abnormal speech perception in schizophrenia with auditory hallucinations","volume":"16","author":"Lee","year":"2004","journal-title":"Acta Neuropsychiatr."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/schbul\/23.2.255","article-title":"Anomalous cerebral asymmetry and language processing in schizophrenia","volume":"23","author":"DeLisi","year":"1997","journal-title":"Schizophr. Bull."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1093\/schbul\/sbp003","article-title":"Reductions in the N1 and P2 auditory event-related potentials in first-hospitalized and chronic schizophrenia","volume":"36","author":"Salisbury","year":"2010","journal-title":"Schizophr. Bull."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.biopsych.2009.07.033","article-title":"Reduced early auditory evoked gamma-band response in patients with schizophrenia","volume":"67","author":"Leicht","year":"2010","journal-title":"Biol. Psychiatry"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.tics.2010.06.008","article-title":"The multifaceted interplay between attention and multisensory integration","volume":"14","author":"Talsma","year":"2010","journal-title":"Trends Cogn. Sci."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1162\/0898929054475172","article-title":"Selective attention and multisensory integration: Multiple phases of effects on the evoked brain activity","volume":"17","author":"Talsma","year":"2005","journal-title":"J. Cogn. Neurosci."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0301-0511(78)90002-9","article-title":"Event-related brain potentials and selective attention to acoustic and phonetic cues","volume":"6","author":"Hink","year":"1978","journal-title":"Biol. Psychol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1469-8986.1987.tb00311.x","article-title":"The N1 wave of the human electric and magnetic response to sound: A review and an analysis of the component structure","volume":"24","author":"Picton","year":"1987","journal-title":"Psychophysiology"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/schbul\/16.3.377","article-title":"Frontal lobes, basal ganglia, temporal lobes\u2014Three sites for schizophrenia?","volume":"16","author":"Buchsbaum","year":"1990","journal-title":"Schizophr. Bull."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1001\/archpsyc.1988.01800310013001","article-title":"Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia: III. A new cohort and evidence for a monoaminergic mechanism","volume":"45","author":"Weinberger","year":"1988","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1001\/archpsyc.1994.03950020048005","article-title":"Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia","volume":"51","author":"Saykin","year":"1994","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1192\/S0007125000296451","article-title":"Memory, knowledge and delusions","volume":"159","author":"McKenna","year":"1991","journal-title":"Br. J. Psychiatry"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.neures.2011.07.004","article-title":"Auditory N1 as a change-related automatic response","volume":"71","author":"Nishihara","year":"2011","journal-title":"Neurosci. Res."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/desc.12098","article-title":"Audio-visual speech perception: A developmental ERP investigation","volume":"17","author":"Knowland","year":"2014","journal-title":"Dev. Sci."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.neulet.2014.11.044","article-title":"Early processing of auditory lexical predictions revealed by ERPs","volume":"585","author":"Baart","year":"2015","journal-title":"Neurosci. Lett."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00406-010-0176-0","article-title":"The N1 auditory evoked potential component as an endophenotype for schizophrenia: High-density electrical mapping in clinically unaffected first-degree relatives, first-episode, and chronic schizophrenia patients","volume":"261","author":"Foxe","year":"2011","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1177\/1550059419868115","article-title":"Deficit effect sizes and correlations of auditory event-related potentials at first hospitalization in the schizophrenia spectrum","volume":"51","author":"Salisbury","year":"2020","journal-title":"Clin. EEG Neurosci."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0006-3223(91)90094-3","article-title":"Auditory event-related potentials and electrodermal activity in medicated and unmedicated schizophrenics","volume":"29","author":"Roth","year":"1991","journal-title":"Biol. Psychiatry"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1600-0447.1990.tb05480.x","article-title":"Influence of stimulation parameters on auditory stimulus processing in schizophrenia and major depression: An auditory evoked potential study","volume":"81","author":"Adler","year":"1990","journal-title":"Acta Psychiatr. Scand."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/schbul\/3.1.93","article-title":"The middle evoked response components and schizophrenia","volume":"3","author":"Buchsbaum","year":"1977","journal-title":"Schizophr. Bull."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1440-1819.1991.tb00506.x","article-title":"Abnormalities in event-related potentials, N100, P200, P300 and slow wave in schizophrenia","volume":"45","author":"Ogura","year":"1991","journal-title":"Psychiatry Clin. Neurosci."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1001\/archpsyc.1989.01810110077011","article-title":"P3 in schizophrenia is affected by stimulus modality, response requirements, medication status, and negative symptoms","volume":"46","author":"Pfefferbaum","year":"1989","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.biopsych.2006.04.015","article-title":"Inherited auditory-cortical dysfunction in twin pairs discordant for schizophrenia","volume":"60","author":"Ahveninen","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.schres.2008.04.038","article-title":"An auditory processing abnormality specific to liability for schizophrenia","volume":"103","author":"Force","year":"2008","journal-title":"Schizophr. Res."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"E90","DOI":"10.1503\/jpn.220149","article-title":"Dexamphetamine widens temporal and spatial binding windows in healthy participants","volume":"48","author":"Kassim","year":"2023","journal-title":"J. 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