{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:36:43Z","timestamp":1787027803729,"version":"build-2736575974"},"reference-count":60,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,7,29]],"date-time":"2023-07-29T00:00:00Z","timestamp":1690588800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Neurosurgery, Technical University of Munich, Germany, School of Medicine, Klinikum rechts der Isar"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>The neural representation of language can be identified cortically using navigated repetitive transcranial magnetic stimulation and subcortically using the fiber tracking of diffusion tensor imaging. We investigated how cortical locations of language and language-eloquent white matter pathways differ in 40 brain lesion patients speaking various languages. Error rates related to stimulations at single sites in the frontal and parietal lobe differed significantly between Balto-Slavic and Indo-European languages. Error rates related to stimulations at single sites in the temporal lobe differed significantly between bilingual individuals. No differences were found in the white matter language pathway volumes between Balto-Slavic and Indo-European languages nor between bilingual patients. These original and exploratory data indicate that the underlying subcortical structure might be similar across languages, with initially observed differences in the cortical location of language depending on the semantic processing, but these could not be confirmed using detailed statistical analyses pointing at a similar cortical and subcortical network.<\/jats:p>","DOI":"10.3390\/brainsci13081141","type":"journal-article","created":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T01:26:40Z","timestamp":1690766800000},"page":"1141","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cortical Location of Language Function May Differ between Languages While White Matter Pathways Are Similar in Brain Lesion Patients"],"prefix":"10.3390","volume":"13","author":[{"given":"Corinna","family":"Boerner","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"},{"name":"TUM-Neuroimaging Center, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"},{"name":"TUM-Neuroimaging Center, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6486-7955","authenticated-orcid":false,"given":"Bernhard","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4050-1531","authenticated-orcid":false,"given":"Sandro M.","family":"Krieg","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"},{"name":"TUM-Neuroimaging Center, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2065-6464","authenticated-orcid":false,"given":"Sebastian","family":"Ille","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"},{"name":"TUM-Neuroimaging Center, Klinikum rechts der Isar, School of Medicine, Technical University Munich, 81675 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3171\/2014.10.JNS132647","article-title":"Contemporary model of language organization: An overview for neurosurgeons","volume":"122","author":"Chang","year":"2015","journal-title":"J. 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