{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:53:59Z","timestamp":1787788439293,"version":"build-2784847793"},"reference-count":110,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,8,15]],"date-time":"2023-08-15T00:00:00Z","timestamp":1692057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background: This meta-analysis aimed to present data on the sella turcica (ST) morphology and variations. Furthermore, a detailed morphometric analysis of the ST was conducted. Methods: Major online databases such as PubMed, Scopus, Embase, Web of Science, and the Cochrane Library were searched through. The overall search process was conducted in three stages. Results: This meta-analysis was based on the results of 18,364 patients and demonstrates the most up-to-date and relevant data regarding the morphology of the ST in the available literature. Four classification methods of the ST shape can be distinguished, in which the most commonly occurring variants are the normal ST (55.56%), the U-shaped ST (73.58%), the circular type of ST (42.29%), and non-bridging ST (55.64%). The overall midpoint height of the ST was 6.59 mm (SE = 0.13). The overall length of the ST was 9.06 mm (SE = 0.15). The overall volume of the ST was 845.80 mm3 (SE = 288.92). Four main classification methods of ST morphology can be distinguished in the available literature. Various morphometric characteristics of the ST may be applied in clinical practice to evaluate its shape, dimensions, and normal or pathological variants.<\/jats:p>","DOI":"10.3390\/brainsci13081208","type":"journal-article","created":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T09:57:02Z","timestamp":1692179822000},"page":"1208","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Morphology of the Sella Turcica: A Meta-Analysis Based on the Results of 18,364 Patients"],"prefix":"10.3390","volume":"13","author":[{"given":"Tomasz","family":"Iskra","sequence":"first","affiliation":[{"name":"Department of Anatomy, Jagiellonian University Medical College Cracow, 33-332 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart\u0142omiej","family":"Stachera","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Jagiellonian University Medical College Cracow, 33-332 Krak\u00f3w, Poland"},{"name":"Youthoria\u2014Youth Research Organization, 33-332 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Mo\u017cd\u017ce\u0144","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Jagiellonian University Medical College Cracow, 33-332 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Murawska","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Jagiellonian University Medical College Cracow, 33-332 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2745-9471","authenticated-orcid":false,"given":"Patryk","family":"Ostrowski","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Jagiellonian University Medical College Cracow, 33-332 Krak\u00f3w, Poland"},{"name":"Youthoria\u2014Youth Research Organization, 33-332 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2080-165X","authenticated-orcid":false,"given":"Micha\u0142","family":"Bonczar","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Jagiellonian University Medical College Cracow, 33-332 Krak\u00f3w, Poland"},{"name":"Youthoria\u2014Youth Research Organization, 33-332 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iwona","family":"Gregorczyk-Maga","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Institute of Dentistry, Jagiellonian University Medical College, 31-155 Krakow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"Walocha","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Jagiellonian University Medical College Cracow, 33-332 Krak\u00f3w, Poland"},{"name":"Youthoria\u2014Youth Research Organization, 33-332 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2635-0776","authenticated-orcid":false,"given":"Mateusz","family":"Koziej","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Jagiellonian University Medical College Cracow, 33-332 Krak\u00f3w, Poland"},{"name":"Youthoria\u2014Youth Research Organization, 33-332 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3631-2295","authenticated-orcid":false,"given":"Grzegorz","family":"Wysiadecki","sequence":"additional","affiliation":[{"name":"Department of Normal and Clinical Anatomy, Chair of Anatomy and Histology, Medical University of Lodz, 90-752 \u0141\u00f3d\u017a, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8706-1927","authenticated-orcid":false,"given":"Krzysztof","family":"Balawender","sequence":"additional","affiliation":[{"name":"Department of Normal and Clinical Anatomy, Institute of Medical Sciences, Medical College, Rzeszow University, 35-315 Rzesz\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"\u017bytkowski","sequence":"additional","affiliation":[{"name":"Norbert Barlicki Memorial Teaching Hospital No. 1, Medical University of Lodz, 90-001 \u0141\u00f3d\u017a, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,15]]},"reference":[{"key":"ref_1","first-page":"46","article-title":"Cone beam computed tomography evaluation of variations in the sella turcica in a Turkish population","volume":"79","author":"Isman","year":"2020","journal-title":"Folia Morphol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2485\/jhtb.26.1","article-title":"3D CT Study of Morphological Shape and Size of Sella Turcica in Bangladeshi Population","volume":"26","author":"Islam","year":"2017","journal-title":"J. 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