{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:03:47Z","timestamp":1760144627496,"version":"build-2065373602"},"reference-count":61,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"LSVT Global (LSVT Global Student Grants (LSVT-SG)"},{"name":"Chaire de Recherche sur les Aphasies Primaires Progressives\u2013Fondation de la Famille Lemaire"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Primary progressive apraxia of speech (PPAOS) is a neurodegenerative syndrome characterized by the progressive and initially isolated or predominant onset of difficulties in the planning\/programming of movements necessary for speech production and can be accompanied by dysarthria. To date, no study has used an evidence-based treatment to address phonation control in patients with PPAOS. The aim of this study was to evaluate the feasibility and efficacy of LSVT LOUD\u00ae as a treatment for phonatory control in speakers with PPAOS. Three speakers with PPAOS received LSVT LOUD\u00ae therapy, and changes in phonatory control, voice quality and prosody were measured immediately, and one, four and eight weeks after the end of the treatment. Overall, the results suggest that the treatment is feasible and could improve voice quality, intensity, and control in some patients with PPAOS. The generalization of the results is also discussed.<\/jats:p>","DOI":"10.3390\/brainsci14050417","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T10:18:36Z","timestamp":1713953916000},"page":"417","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of LSVT LOUD\u00ae on Phonatory Control and Voice Quality in Patients with Primary Progressive Apraxia of Speech: Case Studies"],"prefix":"10.3390","volume":"14","author":[{"given":"Yee Nam Candice","family":"Choi","sequence":"first","affiliation":[{"name":"School of Communication Sciences and Disorders, McGill University, Montr\u00e9al, QC H3A 0G4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0152-0908","authenticated-orcid":false,"given":"Vincent","family":"Martel-Sauvageau","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine, Universit\u00e9 Laval, Qu\u00e9bec, QC G1V 0A6, Canada"},{"name":"CIRRIS\u2014Centre Interdisciplinaire de Recherche en R\u00e9adaptation et Int\u00e9gration Sociale, Qu\u00e9bec, QC G1M 2S8, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myriam","family":"Breton","sequence":"additional","affiliation":[{"name":"CIRRIS\u2014Centre Interdisciplinaire de Recherche en R\u00e9adaptation et Int\u00e9gration Sociale, Qu\u00e9bec, QC G1M 2S8, Canada"},{"name":"CHU de Qu\u00e9bec-Universit\u00e9 Laval, Qu\u00e9bec, QC G1V 0A6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7476-9782","authenticated-orcid":false,"given":"Monica","family":"Lavoie","sequence":"additional","affiliation":[{"name":"Clinique Interdisciplinaire de M\u00e9moire, H\u00f4pital de l\u2019Enfant-J\u00e9sus, Qu\u00e9bec, QC G1J 1Z4, Canada"},{"name":"Chaire de Recherche sur les Aphasies Primaires Progressives\u2014Fondation de la Famille Lemaire, Universit\u00e9 Laval, Qu\u00e9bec, QC G1V 0A6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Robert","family":"Laforce","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine, Universit\u00e9 Laval, Qu\u00e9bec, QC G1V 0A6, Canada"},{"name":"Clinique Interdisciplinaire de M\u00e9moire, H\u00f4pital de l\u2019Enfant-J\u00e9sus, Qu\u00e9bec, QC G1J 1Z4, Canada"},{"name":"Chaire de Recherche sur les Aphasies Primaires Progressives\u2014Fondation de la Famille Lemaire, Universit\u00e9 Laval, Qu\u00e9bec, QC G1V 0A6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liziane","family":"Bouvier","sequence":"additional","affiliation":[{"name":"School of Communication Sciences and Disorders, McGill University, Montr\u00e9al, QC H3A 0G4, Canada"},{"name":"CRIR\u2014Centre for Interdisciplinary Research in Rehabilitation, Montr\u00e9al, QC H3S 1M9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1080\/02687030600597358","article-title":"Apraxia of Speech in Degenerative Neurologic Disease","volume":"20","author":"Duffy","year":"2006","journal-title":"Aphasiology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/1460-6984.12606","article-title":"Progressive Apraxia of Speech in Quebec French-Speakers: A Case Series","volume":"56","author":"Bouvier","year":"2021","journal-title":"Int. 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