{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:48:36Z","timestamp":1791863316491,"version":"4.3.4"},"reference-count":49,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T00:00:00Z","timestamp":1716249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Instituto de Salud Carlos III (Spain)","award":["FIS PI13\/02592"],"award-info":[{"award-number":["FIS PI13\/02592"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background: We aimed to study anxiety, depression and quality of life in smokers after stroke by sex. Methods: A longitudinal prospective study with a 24-month follow-up of acute stroke patients who were previously active smokers. Anxiety and depression were evaluated with the Hospital Anxiety and Depression scale, and quality of life was evaluated with the EQ-5D questionnaire. Results: One hundred and eighty patients participated (79.4% men); their mean age was 57.6 years. Anxiety was most prevalent at 3 months (18.9% in men and 40.5% in women) and depression at 12 months (17.9% in men and 27% in women). The worst perceived health occurred at 24 months (EQ-VAS 67.5 in men and 65.1 in women), which was associated with depression (p &lt; 0.001) and Rankin Scale was worse in men (p &lt; 0.001) and depression in women (p &lt; 0.001). Continued tobacco use was associated with worse perceived health at 3 months in men (p = 0.034) and at 12 months in both sexes. Predictor variables of worse perceived health at 24 months remaining at 3 and 12 months were tobacco use in men and neurological damage in women. Conclusion: Differences by sex are observed in the prevalence of anxiety and depression and associated factors and in the predictive factors of perceived health.<\/jats:p>","DOI":"10.3390\/brainsci14060521","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T08:54:28Z","timestamp":1716281668000},"page":"521","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Sex-Related Differences in Post-Stroke Anxiety, Depression and Quality of Life in a Cohort of Smokers"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7928-9112","authenticated-orcid":false,"given":"Rosa","family":"Su\u00f1er-Soler","sequence":"first","affiliation":[{"name":"Research Group Health and Health Care, Nursing Department, University of Girona, 17003 Girona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3754-4541","authenticated-orcid":false,"given":"Eduard","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Nursing Department, University of Vic, 08242 Manresa, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"Rodrigo-Gil","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dr. Josep Trueta University Hospital, 17007 Girona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4216-3604","authenticated-orcid":false,"given":"Silvia","family":"Font-Mayolas","sequence":"additional","affiliation":[{"name":"Quality of Life Research Institute, University of Girona, 17003 Girona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4765-0871","authenticated-orcid":false,"given":"Maria","family":"Gras","sequence":"additional","affiliation":[{"name":"Quality of Life Research Institute, University of Girona, 17003 Girona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikel","family":"Terce\u00f1o","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dr. Josep Trueta University Hospital, 17007 Girona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9450-8918","authenticated-orcid":false,"given":"Yolanda","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dr. Josep Trueta University Hospital, 17007 Girona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4478-7744","authenticated-orcid":false,"given":"Joaqu\u00edn","family":"Serena","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dr. Josep Trueta University Hospital, 17007 Girona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armand","family":"Grau-Mart\u00edn","sequence":"additional","affiliation":[{"name":"Hospital of Figueres, Fundaci\u00f3 Salut Empord\u00e0, 17600 Figueres, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1161\/CIRCRESAHA.116.308413","article-title":"Global Burden of Stroke","volume":"120","author":"Feigin","year":"2017","journal-title":"Circ. 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